Vaccines and the future of human immunology

Immunity

Volumn 33, Issue 4, 2010, Pages 441-450

  Germain, Ronald N ^a,b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; INFLUENZA VACCINE; MONOCLONAL ANTIBODY; PNEUMOCOCCUS VACCINE; POLIOMYELITIS VACCINE; VACCINE;

ACHIEVEMENT; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; AUTOIMMUNITY; B LYMPHOCYTE; COOPERATION; DATA BASE; DISEASE MARKER; HISTORY OF MEDICINE; HUMAN; IMMUNOLOGY; INFECTION; INFLAMMATION; INFLUENZA; MEDICAL RESEARCH; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE SUBPOPULATION; VACCINATION; VIRUS LIKE AGENT;

ALLERGY AND IMMUNOLOGY; HUMANS; IMMUNE SYSTEM; VACCINES;

EID: 77958479678     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2010.09.014     Document Type: Review

References (89)

1. Ahmed R., Gray D. Immunological memory and protective immunity: Understanding their relation. Science 1996, 272:54-60.
2. Al-Muhsen S., Casanova J.L. The genetic heterogeneity of mendelian susceptibility to mycobacterial diseases. J. Allergy Clin. Immunol. 2008, 122:1043-1051. quiz 1052-1043.
3. Alcaïs A., Abel L., Casanova J.L. Human genetics of infectious diseases: Between proof of principle and paradigm. J. Clin. Invest. 2009, 119:2506-2514.
4. Anderson N.L., Anderson N.G., Pearson T.W., Borchers C.H., Paulovich A.G., Patterson S.D., Gillette M., Aebersold R., Carr S.A. A human proteome detection and quantitation project. Mol. Cell. Proteomics 2009, 8:883-886.
5. Aruffo A., Seed B. Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc. Natl. Acad. Sci. USA 1987, 84:8573-8577.
6. Bandura D.R., Baranov V.I., Ornatsky O.I., Antonov A., Kinach R., Lou X., Pavlov S., Vorobiev S., Dick J.E., Tanner S.D. Mass cytometry: Technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry. Anal. Chem. 2009, 81:6813-6822.
7. Barber D.L., Wherry E.J., Masopust D., Zhu B., Allison J.P., Sharpe A.H., Freeman G.J., Ahmed R. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006, 439:682-687.
8. Bendelac A., Rivera M.N., Park S.H., Roark J.H. Mouse CD1-specific NK1 T cells: Development, specificity, and function. Annu. Rev. Immunol. 1997, 15:535-562.
9. Bernasconi N.L., Traggiai E., Lanzavecchia A. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 2002, 298:2199-2202.
10. Bevan M.J., Fink P.J. The influence of thymus H-2 antigens on the specificity of maturing killer and helper cells. Immunol. Rev. 1978, 42:3-19.
11. Bustamante J., Boisson-Dupuis S., Jouanguy E., Picard C., Puel A., Abel L., Casanova J.L. Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases. Curr. Opin. Immunol. 2008, 20:39-48.
12. Casanova J.L., Fieschi C., Zhang S.Y., Abel L. Revisiting human primary immunodeficiencies. J. Intern. Med. 2008, 264:115-127.
13. Chen K., Cerutti A. Vaccination strategies to promote mucosal antibody responses. Immunity 2010, 33:479-491. this issue.
14. Chandran A., Watt J.P., Santosham M. Prevention of Haemophilus influenzae type b disease: Past success and future challenges. Expert Rev. Vaccines 2005, 4:819-827.
15. Chattopadhyay P.K., Hogerkorp C.M., Roederer M. A chromatic explosion: The development and future of multiparameter flow cytometry. Immunology 2008, 125:441-449.
16. Chaussabel D., Quinn C., Shen J., Patel P., Glaser C., Baldwin N., Stichweh D., Blankenship D., Li L., Munagala I., et al. A modular analysis framework for blood genomics studies: Application to systemic lupus erythematosus. Immunity 2008, 29:150-164.
17. Choudhary C., Mann M. Decoding signalling networks by mass spectrometry-based proteomics. Nat. Rev. Mol. Cell Biol. 2010, 11:427-439.
18. Chun H.J., Lenardo M.J. Autoimmune lymphoproliferative syndrome: Types I, II and beyond. Adv. Exp. Med. Biol. 2001, 490:49-57.
19. Coffman R.L., Sher A., Seder R.A. Vaccine adjuvants: Putting innate immunity to work. Immunity 2010, 33:492-503. this issue.
20. Davis M.M. A prescription for human immunology. Immunity 2008, 29:835-838.
21. Ehl S., Klenerman P., Aichele P., Hengartner H., Zinkernagel R.M. A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro. Eur. J. Immunol. 1997, 27:3404-3413.
22. Fiore A.E., Bridges C.B., Cox N.J. Seasonal influenza vaccines. Curr. Top. Microbiol. Immunol. 2009, 333:43-82.
23. Fontenot J.D., Gavin M.A., Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 2003, 4:330-336.
24. Forsell M.N., Schief W.R., Wyatt R.T. Immunogenicity of HIV-1 envelope glycoprotein oligomers. Curr Opin HIV AIDS 2009, 4:380-387.
25. Freeman J.D., Warren R.L., Webb J.R., Nelson B.H., Holt R.A. Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing. Genome Res. 2009, 19:1817-1824.
26. Gaucher D., Therrien R., Kettaf N., Angermann B.R., Boucher G., Filali-Mouhim A., Moser J.M., Mehta R.S., Drake D.R., Castro E., et al. Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. J. Exp. Med. 2008, 205:3119-3131.
27. Germain R.N. The art of the probable: System control in the adaptive immune system. Science 2001, 293:240-245.
28. Gillison M.L., Chaturvedi A.K., Lowy D.R. HPV prophylactic vaccines and the potential prevention of noncervical cancers in both men and women. Cancer 2008, 113(10, Suppl):3036-3046.
29. Good M.F., Doolan D.L. Malaria vaccine design: Immunological considerations. Immunity 2010, 33:555-566. this issue.
30. Grice E.A., Kong H.H., Conlan S., Deming C.B., Davis J., Young A.C., Bouffard G.G., Blakesley R.W., Murray P.R., Green E.D., et al. Topographical and temporal diversity of the human skin microbiome. Science 2009, 324:1190-1192. NISC Comparative Sequencing Program.
31. Gross C.P., Sepkowitz K.A. The myth of the medical breakthrough: Smallpox, vaccination, and Jenner reconsidered. Int. J. Infect. Dis. 1998, 3:54-60.
32. Gstaiger M., Aebersold R. Applying mass spectrometry-based proteomics to genetics, genomics and network biology. Nat. Rev. Genet. 2009, 10:617-627.
33. Hadrup S.R., Bakker A.H., Shu C.J., Andersen R.S., van Veluw J., Hombrink P., Castermans E., Thor Straten P., Blank C., Haanen J.B., et al. Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers. Nat. Methods 2009, 6:520-526.
34. Hamady M., Knight R. Microbial community profiling for human microbiome projects: Tools, techniques, and challenges. Genome Res. 2009, 19:1141-1152.
35. Henderson D.A. Lessons from the eradication campaigns. Vaccine 1999, 17(Suppl 3):S53-S55.
36. Hori S., Nomura T., Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299:1057-1061.
37. Imboden J.B., Weiss A., Stobo J.D. The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium. J. Immunol. 1985, 134:663-665.
38. Kaufmann S.H.E. Future vaccination strategies against tuberculosis: Thinking outside the box. Immunity 2010, 33:567-577. this issue.
39. Kennedy R.B., Ovsyannikova I.G., Jacobson R.M., Poland G.A. The immunology of smallpox vaccines. Curr. Opin. Immunol. 2009, 21:314-320.
40. Kwong P.D., Wilson I.A. HIV-1 and influenza antibodies: Seeing antigens in new ways. Nat. Immunol. 2009, 10:573-578.
41. Lander E.S., Linton L.M., Birren B., Nusbaum C., Zody M.C., Baldwin J., Devon K., Dewar K., Doyle M., FitzHugh W., et al. Initial sequencing and analysis of the human genome. Nature 2001, 409:860-921. International Human Genome Sequencing Consortium.
42. Lettre G., Rioux J.D. Autoimmune diseases: Insights from genome-wide association studies. Hum. Mol. Genet. 2008, 17(R2):R116-R121.
43. Letvin N.L. Progress toward an HIV vaccine. Annu. Rev. Med. 2005, 56:213-223.
44. Levy J.A. The search for the CD8+ cell anti-HIV factor (CAF). Trends Immunol. 2003, 24:628-632.
45. Li Q., Skinner P.J., Ha S.J., Duan L., Mattila T.L., Hage A., White C., Barber D.L., O'Mara L., Southern P.J., et al. Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science 2009, 323:1726-1729.
46. Liu M.A. Immunologic basis of vaccine vectors. Immunity 2010, 33:504-515. this issue.
47. McElrath M.J., Haynes B.F. Induction of immunity to human immunodeficiency virus type-1 by vaccination. Immunity 2010, 33:542-554. this issue.
48. Mestas J., Hughes C.C. Of mice and not men: Differences between mouse and human immunology. J. Immunol. 2004, 172:2731-2738.
49. Migueles S.A., Osborne C.M., Royce C., Compton A.A., Joshi R.P., Weeks K.A., Rood J.E., Berkley A.M., Sacha J.B., Cogliano-Shutta N.A., et al. Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control. Immunity 2008, 29:1009-1021.
50. Miller J.F. Lymphocyte interactions in antibody responses. Int. Rev. Cytol. 1972, 33:77-130.
51. Milner J.D., Brenchley J.M., Laurence A., Freeman A.F., Hill B.J., Elias K.M., Kanno Y., Spalding C., Elloumi H.Z., Paulson M.L., et al. Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature 2008, 452:773-776.
52. Moskophidis D., Lechner F., Pircher H., Zinkernagel R.M. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 1993, 362:758-761.
53. Newell E.W., Klein L.O., Yu W., Davis M.M. Simultaneous detection of many T-cell specificities using combinatorial tetramer staining. Nat. Methods 2009, 6:497-499.
54. Palucka K., Banchereau J., Mellman I. Designing vaccines based on biology of human dendritic cell subsets. Immunity 2010, 33:464-478. this issue.
55. Picard C., von Bernuth H., Ku C.L., Yang K., Puel A., Casanova J.L. Inherited human IRAK-4 deficiency: An update. Immunol. Res. 2007, 38:347-352.
56. Plotkin S.A. Vaccines: The fourth century. Clin. Vaccine Immunol. 2009, 16:1709-1719.
57. Prince G.A., Hemming V.G., Horswood R.L., Chanock R.M. Immunoprophylaxis and immunotherapy of respiratory syncytial virus infection in the cotton rat. Virus Res. 1985, 3:193-206.
58. Prince G.A., Horswood R.L., Chanock R.M. Quantitative aspects of passive immunity to respiratory syncytial virus infection in infant cotton rats. J. Virol. 1985, 55:517-520.
59. Prince G.A., Horswood R.L., Koenig D.W., Chanock R.M. Antigenic analysis of a putative new strain of respiratory syncytial virus. J. Infect. Dis. 1985, 151:634-637.
60. Pulendran B., Li S., Nakaya H.I. Systems vaccinology. Immunity 2010, 33:516-529. this issue.
61. Querec T.D., Akondy R.S., Lee E.K., Cao W., Nakaya H.I., Teuwen D., Pirani A., Gernert K., Deng J., Marzolf B., et al. Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat. Immunol. 2009, 10:116-125.
62. Ragoussis J. Genotyping technologies for genetic research. Annu. Rev. Genomics Hum. Genet. 2009, 10:117-133.
63. Rappuoli R. Conjugates and reverse vaccinology to eliminate bacterial meningitis. Vaccine 2001, 19:2319-2322.
64. Ravanfar P., Satyaprakash A., Creed R., Mendoza N. Existing antiviral vaccines. Dermatol. Ther. 2009, 22:110-128.
65. Reinherz E.L., Schlossman S.F. The differentiation and function of human T lymphocytes. Cell 1980, 19:821-827.
66. Reinherz E.L., Schlossman S.F. The characterization and function of human immunoregulatory T lymphocyte subsets. Pharmacol. Rev. 1982, 34:17-22.
67. Rerks-Ngarm S., Pitisuttithum P., Nitayaphan S., Kaewkungwal J., Chiu J., Paris R., Premsri N., Namwat C., de Souza M., Adams E., et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 2009, 361:2209-2220. MOPH-TAVEG Investigators.
68. Sallusto F., Lenig D., Förster R., Lipp M., Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999, 401:708-712.
69. Sallusto F., Mackay C.R., Lanzavecchia A. The role of chemokine receptors in primary, effector, and memory immune responses. Annu. Rev. Immunol. 2000, 18:593-620.
70. Schief W.R., Ban Y.E., Stamatatos L. Challenges for structure-based HIV vaccine design. Curr Opin HIV AIDS 2009, 4:431-440.
71. Schiess R., Wollscheid B., Aebersold R. Targeted proteomic strategy for clinical biomarker discovery. Mol. Oncol. 2009, 3:33-44.
72. Schulz K.R., Danna E.A., Krutzik P.O., Nolan G.P. Single-cell phospho-protein analysis by flow cytometry. Curr. Protoc. Immunol. 2007, Chapter 8:8-17.
73. Seder R.A., Ahmed R. Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat. Immunol. 2003, 4:835-842.
74. Seed B., Aruffo A. Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc. Natl. Acad. Sci. USA 1987, 84:3365-3369.
75. Sette A.,, Rappuoli R. Reverse vaccinology: Developing vaccines in the era of genomics. Immunity 2010, 33:530-541. this issue.
76. Sieberts S.K., Schadt E.E. Moving toward a system genetics view of disease. Mamm. Genome 2007, 18:389-401.
77. Silverstein A.M. The History of Immunology. Fundamental Immunology 1999, 19-35. Lippincott-Raven, Philadelphia. 4th Edition. W.E. Paul (Ed.).
78. Steinman R.M., Cohn Z.A. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med. 1973, 137:1142-1162.
79. Su H., Bidère N., Zheng L., Cubre A., Sakai K., Dale J., Salmena L., Hakem R., Straus S., Lenardo M. Requirement for caspase-8 in NF-kappaB activation by antigen receptor. Science 2005, 307:1465-1468.
80. Tiller T., Tsuiji M., Yurasov S., Velinzon K., Nussenzweig M.C., Wardemann H. Autoreactivity in human IgG+ memory B cells. Immunity 2007, 26:205-213.
81. Trimble C.L., Frazer I.H. Development of therapeutic HPV vaccines. Lancet Oncol. 2009, 10:975-980.
82. Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., et al. The sequence of the human genome. Science 2001, 291:1304-1351.
83. Wardemann H., Nussenzweig M.C. B-cell self-tolerance in humans. Adv. Immunol. 2007, 95:83-110.
84. Webster D.P., Farrar J., Rowland-Jones S. Progress towards a dengue vaccine. Lancet Infect. Dis. 2009, 9:678-687.
85. Weiss A., Imboden J., Shoback D., Stobo J. Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proc. Natl. Acad. Sci. USA 1984, 81:4169-4173.
86. Weiss A., Irving B.A., Tan L.K., Koretzky G.A. Signal transduction by the T cell antigen receptor. Semin. Immunol. 1991, 3:313-324.
87. Zinkernagel R.M. Thymus and lymphohemopoietic cells: Their role in T cell maturation in selection of T cells' H-2-restriction-specificity and in H-2 linked Ir gene control. Immunol. Rev. 1978, 42:224-270.
88. Zinkernagel R.M., Doherty P.C. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature 1974, 248:701-702.
89. zur Hausen H. Papillomaviruses in the causation of human cancers - a brief historical account. Virology 2009, 384:260-265.