-
1
-
-
0019423856
-
Sequence and organization of the human mitochondrial genome
-
Anderson S, Bankier AT, Barrell BG, de Bruijn MH, et al., 1981., Sequence and organization of the human mitochondrial genome., Nature, 290: 457-65.
-
(1981)
Nature
, vol.290
, pp. 457-465
-
-
Anderson, S.1
Bankier, A.T.2
Barrell, B.G.3
de Bruijn, M.H.4
-
2
-
-
0014070709
-
On the origin of mitosing cells
-
Sagan L., 1967., On the origin of mitosing cells., J Theor Biol, 14: 255-74.
-
(1967)
J Theor Biol
, vol.14
, pp. 255-274
-
-
Sagan, L.1
-
3
-
-
3343021928
-
Nerve growth factor signaling regulates motility and docking of axonal mitochondria
-
Chada SR, Hollenbeck PJ., 2004., Nerve growth factor signaling regulates motility and docking of axonal mitochondria., Curr Biol, 14: 1272-6.
-
(2004)
Curr Biol
, vol.14
, pp. 1272-1276
-
-
Chada, S.R.1
Hollenbeck, P.J.2
-
4
-
-
0037933255
-
Mitochondrial movement and positioning in axons: the role of growth factor signaling
-
Chada SR, Hollenbeck PJ., 2003., Mitochondrial movement and positioning in axons: the role of growth factor signaling., J Exp Biol, 206: 1985-92.
-
(2003)
J Exp Biol
, vol.206
, pp. 1985-1992
-
-
Chada, S.R.1
Hollenbeck, P.J.2
-
5
-
-
33644552417
-
Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
-
Yu T, Robotham JL, Yoon Y., 2006., Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology., Proc Natl Acad Sci USA, 103: 2653-8.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2653-2658
-
-
Yu, T.1
Robotham, J.L.2
Yoon, Y.3
-
6
-
-
77955509429
-
Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes
-
Makino A, Scott BT, Dillmann WH., 2010., Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes., Diabetologia, 53: 1783-94.
-
(2010)
Diabetologia
, vol.53
, pp. 1783-1794
-
-
Makino, A.1
Scott, B.T.2
Dillmann, W.H.3
-
7
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig G, Elorza A, Molina AJ, Mohamed H, et al., 2008., Fission and selective fusion govern mitochondrial segregation and elimination by autophagy., EMBO J, 27: 433-46.
-
(2008)
EMBO J
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
-
8
-
-
0032547845
-
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p
-
Hermann GJ, Thatcher JW, Mills JP, Hales KG, et al., 1998., Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p., J Cell Biol, 143: 359-73.
-
(1998)
J Cell Biol
, vol.143
, pp. 359-373
-
-
Hermann, G.J.1
Thatcher, J.W.2
Mills, J.P.3
Hales, K.G.4
-
9
-
-
0032493625
-
Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochonrdia in Saccharomyces cerevisiae
-
Rapaport D, Brunner M, Neupert W, Westerman B., 1998., Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochonrdia in Saccharomyces cerevisiae., J Biol Chem, 273: 20150-5.
-
(1998)
J Biol Chem
, vol.273
, pp. 20150-20155
-
-
Rapaport, D.1
Brunner, M.2
Neupert, W.3
Westerman, B.4
-
10
-
-
1542380494
-
Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission
-
Harder Z, Zunino R, McBride H., 2004., Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission., Curr Biol, 14: 340-5.
-
(2004)
Curr Biol
, vol.14
, pp. 340-345
-
-
Harder, Z.1
Zunino, R.2
McBride, H.3
-
11
-
-
34848840991
-
Reversible phosphorylation of Drp1 by cyclic AMPdependent protein kinase and calcineurin regulates mitochondrial fission and cell death
-
Cribbs JT, Strack S., 2007., Reversible phosphorylation of Drp1 by cyclic AMPdependent protein kinase and calcineurin regulates mitochondrial fission and cell death., EMBO Rep, 8: 939-44.
-
(2007)
EMBO Rep
, vol.8
, pp. 939-944
-
-
Cribbs, J.T.1
Strack, S.2
-
12
-
-
34347398050
-
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
-
Karbowski M, Neutzner A, Youle RJ., 2007., The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division., J Cell Biol, 178: 71-84.
-
(2007)
J Cell Biol
, vol.178
, pp. 71-84
-
-
Karbowski, M.1
Neutzner, A.2
Youle, R.J.3
-
13
-
-
64249133725
-
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury
-
Cho DH, Nakamura T, Fang J, Cieplak P, et al., 2009., S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury., Science, 324: 102-5.
-
(2009)
Science
, vol.324
, pp. 102-105
-
-
Cho, D.H.1
Nakamura, T.2
Fang, J.3
Cieplak, P.4
-
14
-
-
77955431941
-
S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease
-
Bossy B, Petrilli A, Klinglmayr E, Chen J, et al., 2010., S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease., J Alzheimers Dis, 20: S513-26.
-
(2010)
J Alzheimers Dis
, vol.20
-
-
Bossy, B.1
Petrilli, A.2
Klinglmayr, E.3
Chen, J.4
-
15
-
-
0035421320
-
Propagation of the apoptotic signal by mitochondrial waves
-
Pacher P, Hajnoczky G., 2001., Propagation of the apoptotic signal by mitochondrial waves., EMBO J, 20: 4107-21.
-
(2001)
EMBO J
, vol.20
, pp. 4107-4121
-
-
Pacher, P.1
Hajnoczky, G.2
-
17
-
-
33845656956
-
Mitochondrial retrograde signaling
-
Liu Z, Butow RA., 2006., Mitochondrial retrograde signaling., Annu Rev Genet, 40: 159-85.
-
(2006)
Annu Rev Genet
, vol.40
, pp. 159-185
-
-
Liu, Z.1
Butow, R.A.2
-
18
-
-
2442490089
-
Self-regulated cleavage of the mitochondrial intramembrane-cleaving protease PARL yields Pbeta, a nuclear-targeted peptide
-
Sik A, Passer BJ, Koonin EV, Pellegrini L., 2004., Self-regulated cleavage of the mitochondrial intramembrane-cleaving protease PARL yields Pbeta, a nuclear-targeted peptide., J Biol Chem, 279: 15323-9.
-
(2004)
J Biol Chem
, vol.279
, pp. 15323-15329
-
-
Sik, A.1
Passer, B.J.2
Koonin, E.V.3
Pellegrini, L.4
-
19
-
-
77955284487
-
Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL
-
Civitarese AE, MacLean PS, Carling S, Kerr-Bayles L, et al., 2010., Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL., Cell Metab, 11: 412-26.
-
(2010)
Cell Metab
, vol.11
, pp. 412-426
-
-
Civitarese, A.E.1
MacLean, P.S.2
Carling, S.3
Kerr-Bayles, L.4
-
20
-
-
38349023008
-
Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers
-
Neuspiel M, Schauss AC, Braschi E, Zunino R, et al., 2008., Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers., Curr Biol, 18: 102-8.
-
(2008)
Curr Biol
, vol.18
, pp. 102-108
-
-
Neuspiel, M.1
Schauss, A.C.2
Braschi, E.3
Zunino, R.4
-
21
-
-
67949111205
-
Mitochondrial vesicles: an ancient process providing new links to peroxisomes
-
Andrade-Navarro MA, Sanchez-Pulido L, McBride HM., 2009., Mitochondrial vesicles: an ancient process providing new links to peroxisomes., Curr Opin Cell Biol, 21: 560-7.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 560-567
-
-
Andrade-Navarro, M.A.1
Sanchez-Pulido, L.2
McBride, H.M.3
-
22
-
-
77955276502
-
Organellar vs cellular control of mitochondrial dynamics
-
Hyde BB, Twig G, Shirihai OS., 2010., Organellar vs cellular control of mitochondrial dynamics., Semin Cell Dev Biol, 21: 575-81.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 575-581
-
-
Hyde, B.B.1
Twig, G.2
Shirihai, O.S.3
-
23
-
-
0037455575
-
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
-
Chen H, Detmer SA, Ewald AJ, Griffin EE, et al., 2003., Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development., J Cell Biol, 160: 189-200.
-
(2003)
J Cell Biol
, vol.160
, pp. 189-200
-
-
Chen, H.1
Detmer, S.A.2
Ewald, A.J.3
Griffin, E.E.4
-
24
-
-
68249087424
-
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
-
Ishihara N, Nomura M, Jofuku A, Kato H, et al., 2009., Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice., Nat Cell Biol, 11: 958-66.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 958-966
-
-
Ishihara, N.1
Nomura, M.2
Jofuku, A.3
Kato, H.4
-
25
-
-
70349944660
-
The dynaminrelated GTPase Drp1 is required for embryonic and brain development in mice
-
Wakabayashi J, Zhang Z, Wakabayashi N, Tamura Y, et al., 2009., The dynaminrelated GTPase Drp1 is required for embryonic and brain development in mice., J Cell Biol, 186: 805-16.
-
(2009)
J Cell Biol
, vol.186
, pp. 805-816
-
-
Wakabayashi, J.1
Zhang, Z.2
Wakabayashi, N.3
Tamura, Y.4
-
26
-
-
56349103980
-
The molecular mechanism of mitochondrial fusion
-
Hoppins S, Nunnari J., 2009., The molecular mechanism of mitochondrial fusion., Biochim Biophys Acta, 1793: 20-6.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 20-26
-
-
Hoppins, S.1
Nunnari, J.2
-
27
-
-
34547601410
-
Mitochondrial fusion protects against neurodegeneration in the cerebellum
-
Chen H, McCaffery JM, Chan DC., 2007., Mitochondrial fusion protects against neurodegeneration in the cerebellum., Cell, 130: 548-62.
-
(2007)
Cell
, vol.130
, pp. 548-562
-
-
Chen, H.1
McCaffery, J.M.2
Chan, D.C.3
-
28
-
-
77951737783
-
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
-
Chen H, Vermulst M, Wang YE, Chomyn A, et al., 2010., Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations., Cell, 141: 280-9.
-
(2010)
Cell
, vol.141
, pp. 280-289
-
-
Chen, H.1
Vermulst, M.2
Wang, Y.E.3
Chomyn, A.4
-
29
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
de Brito OM, Scorrano L., 2008., Mitofusin 2 tethers endoplasmic reticulum to mitochondria., Nature, 456: 605-10.
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
de Brito, O.M.1
Scorrano, L.2
-
30
-
-
76149140917
-
Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1
-
Ehses S, Raschke I, Mancuso G, Bernacchia A, et al., 2009., Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1., J Cell Biol, 187: 1023-36.
-
(2009)
J Cell Biol
, vol.187
, pp. 1023-1036
-
-
Ehses, S.1
Raschke, I.2
Mancuso, G.3
Bernacchia, A.4
-
31
-
-
76149093590
-
Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells
-
Head B, Griparic L, Amiri M, Gandre-Babbe S, et al., 2009., Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells., J Cell Biol, 187: 959-66.
-
(2009)
J Cell Biol
, vol.187
, pp. 959-966
-
-
Head, B.1
Griparic, L.2
Amiri, M.3
Gandre-Babbe, S.4
-
32
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza C, Zhou C, Huang Y, Cui M, et al., 2010., PINK1-dependent recruitment of Parkin to mitochondria in mitophagy., Proc Natl Acad Sci USA, 107: 378-83.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
-
33
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S, Holmstrom KM, Skujat D, Fiesel FC, et al., 2010., PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1., Nat Cell Biol, 12: 119-31.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
-
34
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate parkin
-
Narendra DP, Jin SM, Tanaka A, Suen DF, et al., 2010., PINK1 is selectively stabilized on impaired mitochondria to activate parkin., PLoS Biol, 8: e1000298.
-
(2010)
PLoS Biol
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
-
35
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda N, Sato S, Shiba K, Okatsu K, et al., 2010., PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy., J Cell Biol, 189: 211-21.
-
(2010)
J Cell Biol
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
-
36
-
-
77953877676
-
A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease
-
Chu CT., 2010., A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease., Hum Mol Genet, 19: R28-37.
-
(2010)
Hum Mol Genet
, vol.19
-
-
Chu, C.T.1
-
37
-
-
77955844260
-
The mitochondrial fusionpromoting factor mitofusin is a substrate of the PINK1/parkin pathway
-
Poole AC, Thomas RE, Yu S, Vincow ES, et al., 2010., The mitochondrial fusionpromoting factor mitofusin is a substrate of the PINK1/parkin pathway., PLoS One, 5: e10054.
-
(2010)
PLoS One
, vol.5
-
-
Poole, A.C.1
Thomas, R.E.2
Yu, S.3
Vincow, E.S.4
-
38
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
Ziviani E, Tao RN, Whitworth AJ., 2010., Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin., Proc Natl Acad Sci USA, 107: 5018-23.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
39
-
-
67650348459
-
Frequency and selectivity of mitochondrial fusion are key to its quality maintenance function
-
Mouli PK, Twig G, Shirihai OS., 2009., Frequency and selectivity of mitochondrial fusion are key to its quality maintenance function., Biophys J, 96: 3509-18.
-
(2009)
Biophys J
, vol.96
, pp. 3509-3518
-
-
Mouli, P.K.1
Twig, G.2
Shirihai, O.S.3
-
40
-
-
34249689057
-
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
-
Taguchi N, Ishihara N, Jofuku A, Oka T, et al., 2007., Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission., J Biol Chem, 282: 11521-9.
-
(2007)
J Biol Chem
, vol.282
, pp. 11521-11529
-
-
Taguchi, N.1
Ishihara, N.2
Jofuku, A.3
Oka, T.4
-
41
-
-
67650534951
-
Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis
-
Zunino R, Braschi E, Xu L, McBride HM., 2009., Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis., J Biol Chem, 284: 17783-95.
-
(2009)
J Biol Chem
, vol.284
, pp. 17783-17795
-
-
Zunino, R.1
Braschi, E.2
Xu, L.3
McBride, H.M.4
-
42
-
-
0035487808
-
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
-
Frank S, Gaume B, Bergmann-Leitner ES, Leitner WW, et al., 2001., The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis., Dev Cell, 1: 515-25.
-
(2001)
Dev Cell
, vol.1
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
-
43
-
-
45349094984
-
Mitochondrial dynamics and apoptosis
-
Suen DF, Norris KL, Youle RJ., 2008., Mitochondrial dynamics and apoptosis., Genes Dev, 22: 1577-90.
-
(2008)
Genes Dev
, vol.22
, pp. 1577-1590
-
-
Suen, D.F.1
Norris, K.L.2
Youle, R.J.3
-
44
-
-
67749089562
-
A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase
-
Mitra K, Wunder C, Roysam B, Lin G, et al., 2009., A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase., Proc Natl Acad Sci USA, 106: 11960-5.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11960-11965
-
-
Mitra, K.1
Wunder, C.2
Roysam, B.3
Lin, G.4
-
45
-
-
67049089786
-
SLP-2 is required for stress-induced mitochondrial hyperfusion
-
Tondera D, Grandemange S, Jourdain A, Karbowski M, et al., 2009., SLP-2 is required for stress-induced mitochondrial hyperfusion., EMBO J, 28: 1589-600.
-
(2009)
EMBO J
, vol.28
, pp. 1589-1600
-
-
Tondera, D.1
Grandemange, S.2
Jourdain, A.3
Karbowski, M.4
-
46
-
-
0036242518
-
Cell cycle dependent morphology changes and associated mitochondrial DNA redistribution in mitochondria of human cell lines
-
Margineantu DH, Gregory Cox, W, Sundell L, Sherwood SW, et al., 2002., Cell cycle dependent morphology changes and associated mitochondrial DNA redistribution in mitochondria of human cell lines., Mitochondrion, 1: 425-35.
-
(2002)
Mitochondrion
, vol.1
, pp. 425-435
-
-
Margineantu, D.H.1
Gregory Cox, W.2
Sundell, L.3
Sherwood, S.W.4
-
47
-
-
36049043184
-
Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38
-
Bai X, Ma D, Liu A, Shen X, et al., 2007., Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38., Science, 318: 977-80.
-
(2007)
Science
, vol.318
, pp. 977-980
-
-
Bai, X.1
Ma, D.2
Liu, A.3
Shen, X.4
-
48
-
-
36749081539
-
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex
-
Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, et al., 2007., mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex., Nature, 450: 736-40.
-
(2007)
Nature
, vol.450
, pp. 736-740
-
-
Cunningham, J.T.1
Rodgers, J.T.2
Arlow, D.H.3
Vazquez, F.4
-
49
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen C, Liu Y, Liu R, Ikenoue T, et al., 2008., TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species., J Exp Med, 205: 2397-408.
-
(2008)
J Exp Med
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
-
50
-
-
72449133773
-
Diabetes regulates mitochondrial biogenesis and fission in mouse neurons
-
Edwards JL, Quattrini A, Lentz SI, Figueroa-Romero C, et al., 2010., Diabetes regulates mitochondrial biogenesis and fission in mouse neurons., Diabetologia, 53: 160-9.
-
(2010)
Diabetologia
, vol.53
, pp. 160-169
-
-
Edwards, J.L.1
Quattrini, A.2
Lentz, S.I.3
Figueroa-Romero, C.4
-
51
-
-
77949568291
-
Mitochondrial dysfunction is induced by high levels of glucose and free fatty acids in 3T3-L1 adipocytes
-
Gao CL, Zhu C, Zhao YP, Chen XH, et al., 2010., Mitochondrial dysfunction is induced by high levels of glucose and free fatty acids in 3T3-L1 adipocytes., Mol Cell Endocrinol, 320: 25-33.
-
(2010)
Mol Cell Endocrinol
, vol.320
, pp. 25-33
-
-
Gao, C.L.1
Zhu, C.2
Zhao, Y.P.3
Chen, X.H.4
-
52
-
-
77952236126
-
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury
-
Ong SB, Subrayan S, Lim SY, Yellon DM, et al., 2010., Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury., Circulation, 121: 2012-22.
-
(2010)
Circulation
, vol.121
, pp. 2012-2022
-
-
Ong, S.B.1
Subrayan, S.2
Lim, S.Y.3
Yellon, D.M.4
-
54
-
-
34248182897
-
Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death
-
Wasiak S, Zunino R, McBride HM., 2007., Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death., J Cell Biol, 177: 439-50.
-
(2007)
J Cell Biol
, vol.177
, pp. 439-450
-
-
Wasiak, S.1
Zunino, R.2
McBride, H.M.3
-
55
-
-
77957851365
-
Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin
-
May 21. [Epub ahead of print]
-
Cereghetti GM, Costa V, Scorrano L., 2010., Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin., Cell Death Differ, May 21. [Epub ahead of print]
-
(2010)
Cell Death Differ
-
-
Cereghetti, G.M.1
Costa, V.2
Scorrano, L.3
-
56
-
-
57349160257
-
Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
-
Cereghetti GM, Stangherlin A, Martins de Brito O, Chang CR, et al., 2008., Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria., Proc Natl Acad Sci USA, 105: 15803-8.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15803-15808
-
-
Cereghetti, G.M.1
Stangherlin, A.2
Martins de Brito, O.3
Chang, C.R.4
-
57
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole AC, Thomas RE, Andrews LA, McBride HM, et al., 2008., The PINK1/Parkin pathway regulates mitochondrial morphology., Proc Natl Acad Sci USA, 105: 1638-43.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
-
58
-
-
77951235489
-
Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1
-
Cui M, Tang X, Christian WV, Yoon Y, et al., 2010., Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1., J Biol Chem, 285: 11740-52.
-
(2010)
J Biol Chem
, vol.285
, pp. 11740-11752
-
-
Cui, M.1
Tang, X.2
Christian, W.V.3
Yoon, Y.4
-
59
-
-
0036007116
-
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis
-
Scorrano L, Ashiya M, Buttle K, Weiler S, et al., 2002., A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis., Dev Cell, 2: 55-67.
-
(2002)
Dev Cell
, vol.2
, pp. 55-67
-
-
Scorrano, L.1
Ashiya, M.2
Buttle, K.3
Weiler, S.4
-
60
-
-
33745699393
-
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion
-
Frezza C, Cipolat S, Martins de Brito O, Micaroni M, et al., 2006., OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion., Cell, 126: 177-89.
-
(2006)
Cell
, vol.126
, pp. 177-189
-
-
Frezza, C.1
Cipolat, S.2
Martins de Brito, O.3
Micaroni, M.4
-
61
-
-
77951211107
-
The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis
-
Siskind LJ, Mullen TD, Romero Rosales K, Clarke CJ, et al., 2010., The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis., J Biol Chem, 285: 11818-26.
-
(2010)
J Biol Chem
, vol.285
, pp. 11818-11826
-
-
Siskind, L.J.1
Mullen, T.D.2
Romero Rosales, K.3
Clarke, C.J.4
-
62
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
Muchmore SW, Sattler M, Liang H, Meadows RP, et al., 1996., X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death., Nature, 381: 335-41.
-
(1996)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
Meadows, R.P.4
-
63
-
-
14044251695
-
Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution
-
Kroemer G., 1997., Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution., Cell Death Differ, 4: 443-56.
-
(1997)
Cell Death Differ
, vol.4
, pp. 443-456
-
-
Kroemer, G.1
-
64
-
-
0028963606
-
Programmed cell death in bacterial populations
-
Yarmolinsky MB., 1995., Programmed cell death in bacterial populations., Science, 267: 836-7.
-
(1995)
Science
, vol.267
, pp. 836-837
-
-
Yarmolinsky, M.B.1
-
65
-
-
77952566949
-
Mechanisms, regulation and consequences of protein SUMOylation
-
Wilkinson KA, Henley JM., 2010., Mechanisms, regulation and consequences of protein SUMOylation., Biochem J, 428: 133-45.
-
(2010)
Biochem J
, vol.428
, pp. 133-145
-
-
Wilkinson, K.A.1
Henley, J.M.2
-
66
-
-
0033615965
-
Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins
-
Johnson ES, Blobel G., 1999., Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins., J Cell Biol, 147: 981-94.
-
(1999)
J Cell Biol
, vol.147
, pp. 981-994
-
-
Johnson, E.S.1
Blobel, G.2
-
67
-
-
0035929279
-
An E3-like factor that promotes SUMO conjugation to the yeast septins
-
Johnson ES, Gupta AA., 2001., An E3-like factor that promotes SUMO conjugation to the yeast septins., Cell, 106: 735-44.
-
(2001)
Cell
, vol.106
, pp. 735-744
-
-
Johnson, E.S.1
Gupta, A.A.2
-
68
-
-
34247103108
-
The role of karyopherins in the regulated sumoylation of septins
-
Makhnevych T, Ptak C, Lusk CP, Aitchison JD, et al., 2007., The role of karyopherins in the regulated sumoylation of septins., J Cell Biol, 177: 39-49.
-
(2007)
J Cell Biol
, vol.177
, pp. 39-49
-
-
Makhnevych, T.1
Ptak, C.2
Lusk, C.P.3
Aitchison, J.D.4
-
69
-
-
34248225298
-
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function
-
Zunino R, Schauss A, Rippstein P, Andrade-Navarro M, et al., 2007., The SUMO protease SENP5 is required to maintain mitochondrial morphology and function., J Cell Sci, 120: 1178-88.
-
(2007)
J Cell Sci
, vol.120
, pp. 1178-1188
-
-
Zunino, R.1
Schauss, A.2
Rippstein, P.3
Andrade-Navarro, M.4
-
70
-
-
67650076601
-
MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission
-
Braschi E, Zunino R, McBride HM., 2009., MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission., EMBO Rep, 10: 748-54.
-
(2009)
EMBO Rep
, vol.10
, pp. 748-754
-
-
Braschi, E.1
Zunino, R.2
McBride, H.M.3
-
71
-
-
44949231368
-
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling
-
Li W, Bengtson MH, Ulbrich A, Matsuda A, et al., 2008., Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling., PLoS ONE, 3: e1487.
-
(2008)
PLoS ONE
, vol.3
-
-
Li, W.1
Bengtson, M.H.2
Ulbrich, A.3
Matsuda, A.4
-
72
-
-
51049095678
-
GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth
-
Zhang B, Huang J, Li HL, Liu T, et al., 2008., GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth., Cell Res, 18: 900-10.
-
(2008)
Cell Res
, vol.18
, pp. 900-910
-
-
Zhang, B.1
Huang, J.2
Li, H.L.3
Liu, T.4
-
73
-
-
34250204271
-
The machines that divide and fuse mitochondria
-
Hoppins S, Lackner L, Nunnari J., 2007., The machines that divide and fuse mitochondria., Annu Rev Biochem, 76: 751-80.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 751-780
-
-
Hoppins, S.1
Lackner, L.2
Nunnari, J.3
-
74
-
-
70350543964
-
SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle
-
Figueroa-Romero C, Iniguez-Lluhi JA, Stadler J, Chang CR, et al., 2009., SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle., FASEB J, 23: 3917-27.
-
(2009)
FASEB J
, vol.23
, pp. 3917-3927
-
-
Figueroa-Romero, C.1
Iniguez-Lluhi, J.A.2
Stadler, J.3
Chang, C.R.4
-
75
-
-
34547611925
-
Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology
-
Chang CR, Blackstone C., 2007., Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology., J Biol Chem, 282: 21583-7.
-
(2007)
J Biol Chem
, vol.282
, pp. 21583-21587
-
-
Chang, C.R.1
Blackstone, C.2
-
76
-
-
49749118684
-
CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology
-
Han XJ, Lu YF, Li SA, Kaitsuka T, et al., 2008., CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology., J Cell Biol, 182: 573-85.
-
(2008)
J Cell Biol
, vol.182
, pp. 573-585
-
-
Han, X.J.1
Lu, Y.F.2
Li, S.A.3
Kaitsuka, T.4
-
77
-
-
33749253910
-
MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology
-
Nakamura N, Kimura Y, Tokuda M, Honda S, et al., 2006., MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology., EMBO Rep, 7: 1019-22.
-
(2006)
EMBO Rep
, vol.7
, pp. 1019-1022
-
-
Nakamura, N.1
Kimura, Y.2
Tokuda, M.3
Honda, S.4
-
78
-
-
33747613595
-
A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics
-
Yonashiro R, Ishido S, Kyo S, Fukuda T, et al., 2006., A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics., EMBO J, 25: 3618-26.
-
(2006)
EMBO J
, vol.25
, pp. 3618-3626
-
-
Yonashiro, R.1
Ishido, S.2
Kyo, S.3
Fukuda, T.4
-
79
-
-
76649142385
-
Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1
-
Park YY, Lee S, Karbowski M, Neutzner A, et al., 2010., Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1., J Cell Sci, 123: 619-26.
-
(2010)
J Cell Sci
, vol.123
, pp. 619-626
-
-
Park, Y.Y.1
Lee, S.2
Karbowski, M.3
Neutzner, A.4
-
80
-
-
48749116067
-
Ubiquitin-proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion
-
Cohen MM, Leboucher GP, Livnat-Levanon N, Glickman MH, et al., 2008., Ubiquitin-proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion., Mol Biol Cell, 19: 2457-64.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2457-2464
-
-
Cohen, M.M.1
Leboucher, G.P.2
Livnat-Levanon, N.3
Glickman, M.H.4
-
81
-
-
21444442598
-
Instability of the mitofusin Fzo1 regulates mitochondrial morphology during the mating response of the yeast Saccharomyces cerevisiae
-
Neutzner A, Youle RJ., 2005., Instability of the mitofusin Fzo1 regulates mitochondrial morphology during the mating response of the yeast Saccharomyces cerevisiae., J Biol Chem, 280: 18598-603.
-
(2005)
J Biol Chem
, vol.280
, pp. 18598-18603
-
-
Neutzner, A.1
Youle, R.J.2
-
82
-
-
73949125579
-
A mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover
-
Amiott EA, Cohen MM, Saint-Georges Y, Weissman AM, et al., 2009., A mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover., Mol Biol Cell, 20: 5026-35.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 5026-5035
-
-
Amiott, E.A.1
Cohen, M.M.2
Saint-Georges, Y.3
Weissman, A.M.4
-
83
-
-
77951096150
-
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
-
Chen H, Chan DC., 2009., Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases., Hum Mol Genet, 18: R169-76.
-
(2009)
Hum Mol Genet
, vol.18
-
-
Chen, H.1
Chan, D.C.2
-
84
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
-
Wang X, Su B, Lee HG, Li X, et al., 2009., Impaired balance of mitochondrial fission and fusion in Alzheimer's disease., J Neurosci, 29: 9090-103.
-
(2009)
J Neurosci
, vol.29
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
Li, X.4
-
85
-
-
0033032999
-
Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia
-
Schapira AHV., 1999., Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia., Biochem Biophys Acta, 1410: 159-70.
-
(1999)
Biochem Biophys Acta
, vol.1410
, pp. 159-170
-
-
Schapira, A.H.V.1
-
86
-
-
58949099388
-
Effects of overexpression of huntingtin proteins on mitochondrial integrity
-
Wang H, Lim PJ, Karbowski M, Monteiro MJ., 2009., Effects of overexpression of huntingtin proteins on mitochondrial integrity., Hum Mol Genet, 18: 737-52.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 737-752
-
-
Wang, H.1
Lim, P.J.2
Karbowski, M.3
Monteiro, M.J.4
-
87
-
-
76749098103
-
Parkinson's disease: mitochondrial damage control
-
Abeliovich A., 2010., Parkinson's disease: mitochondrial damage control., Nature, 463: 744-5.
-
(2010)
Nature
, vol.463
, pp. 744-745
-
-
Abeliovich, A.1
-
88
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, et al., 2005., Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus., Nature, 437: 1167-72.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
-
89
-
-
27144440523
-
IPS-1, an adaptor triggering RIGI- and Mda5-mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S, Coban C, et al., 2005., IPS-1, an adaptor triggering RIGI- and Mda5-mediated type I interferon induction., Nat Immunol, 6: 981-8.
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
-
90
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu LG, Wang YY, Han KJ, Li LY, et al., 2005., VISA is an adapter protein required for virus-triggered IFN-beta signaling., Mol Cell, 19: 727-40.
-
(2005)
Mol Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
-
91
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ., 2005., Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3., Cell, 122: 669-82.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
92
-
-
77952885088
-
The role of mitochondria in the mammalian antiviral defense system
-
Scott I., 2010., The role of mitochondria in the mammalian antiviral defense system., Mitochondrion, 10: 316-20.
-
(2010)
Mitochondrion
, vol.10
, pp. 316-320
-
-
Scott, I.1
-
93
-
-
75949098312
-
Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway
-
Castanier C, Garcin D, Vazquez A, Arnoult D., 2010., Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway., EMBO Rep, 11: 133-8.
-
(2010)
EMBO Rep
, vol.11
, pp. 133-138
-
-
Castanier, C.1
Garcin, D.2
Vazquez, A.3
Arnoult, D.4
-
94
-
-
70350468688
-
Mitofusin 2 inhibits mitochondrial antiviral signaling
-
Yasukawa K, Oshiumi H, Takeda M, Ishihara N, et al., 2009., Mitofusin 2 inhibits mitochondrial antiviral signaling., Sci Signal, 2: ra47.
-
(2009)
Sci Signal
, vol.2
-
-
Yasukawa, K.1
Oshiumi, H.2
Takeda, M.3
Ishihara, N.4
-
95
-
-
77953153023
-
The mitochondrion - a Trojan horse that kicks off inflammation?
-
Manfredi AA, Rovere-Querini P., 2010., The mitochondrion - a Trojan horse that kicks off inflammation?, N Engl J Med, 362: 2132-4.
-
(2010)
N Engl J Med
, vol.362
, pp. 2132-2134
-
-
Manfredi, A.A.1
Rovere-Querini, P.2
-
96
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Zhang Q, Raoof M, Chen Y, Sumi Y, et al., 2010., Circulating mitochondrial DAMPs cause inflammatory responses to injury., Nature, 464: 104-7.
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
Sumi, Y.4
|