Self-regulated Cleavage of the Mitochondrial Intramembrane-cleaving Protease PARL Yields Pβ, a Nuclear-targeted Peptide

Journal of Biological Chemistry

Volumn 279, Issue 15, 2004, Pages 15323-15329

  Sík, Attila ^a,b   Passer, Brent J ^c   Koonin, Eugene V ^d   Pellegrini, Luca ^a,b  

^a CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

^c Molecular Engines Laboratories   (France)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; BIOLOGICAL MEMBRANES; PROTEINS; YEAST;

PRECURSOR PROTEINS; REGULATED INTRAMEMBRANE PROTEOLYSIS (RIP);

BIOCHEMISTRY;

P BETA PEPTIDE; PEPTIDE; PRESENILIN ASSOCIATED RHOMBOID LIKE PROTEIN; PROTEIN; PROTEIN PRECURSOR; PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CYTOSOL; DNA CLEAVAGE; ENZYME ACTIVITY; ENZYME REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MOLECULAR DYNAMICS; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; REGULATED INTRAMEMBRANE PROTEOLYSIS; SIGNAL TRANSDUCTION; TARGET CELL;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL NUCLEUS; COS CELLS; CYTOSOL; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; METALLOPROTEASES; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PEPTIDES; PRECIPITIN TESTS; PRESENILIN-1; PROTEIN STRUCTURE, TERTIARY; RATS; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

MAMMALIA; VERTEBRATA;

EID: 2442490089     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313756200     Document Type: Article

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