Structural analysis of a highly glycosylated and unliganded gp120-based antigen using mass spectrometry

Biochemistry

Volumn 49, Issue 42, 2010, Pages 9032-9045

  Wang, Liwen ^a   Qin, Yali ^b   Ilchenko, Serguei ^a   Bohon, Jen ^a,c   Shi, Wuxian ^a,c   Cho, Michael W ^b   Takamoto, Keiji ^d   Chance, Mark R ^a,c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; CELL MEMBRANES; DISEASES; ESTERIFICATION; GLYCOSYLATION; MASS SPECTROMETRY; STRUCTURAL ANALYSIS; SUGAR (SUCROSE); VIRUSES;

CELL RECEPTORS; CORECEPTOR BINDING; CRYSTALLOGRAPHIC STRUCTURE; ENVELOPE PROTEINS; FOOTPRINTING; GLYCOPEPTIDES; GLYCOSYLATED; HOMOLOGY MODELS; HYDROXYL RADICALS; IMMUNOGENICITY; LOOP STRUCTURE; MASS SPECTROMETRY ANALYSIS; OUTER DOMAIN; PROTEIN FOOTPRINTING; PROTEIN STRUCTURES; SIDE CHAIN RESIDUES; SIDE CHAINS; STRUCTURAL CHARACTERIZATION; SUGAR MOIETY; T CELLS;

CRYSTAL STRUCTURE;

GLYCOPROTEIN GP 120; MANNOSE; GP120 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; HIV ENVELOPE PROTEIN GP120 (305-321); HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; IMMUNOGLOBULIN G; LIGAND; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; ELECTRON CAPTURE DETECTION; GLYCOSYLATION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DROSOPHILA; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SURFACE PLASMON RESONANCE; TANDEM MASS SPECTROMETRY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; DROSOPHILA; GLYCOSYLATION; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; IMMUNOGLOBULIN G; IN VITRO TECHNIQUES; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE; TANDEM MASS SPECTROMETRY;

EID: 77958096976     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1011332     Document Type: Article

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