Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways

Journal of Virology

Volumn 84, Issue 21, 2010, Pages 11350-11358

  Melchjorsen, Jesper ^a   Rintahaka, Johanna ^b   Søby, Stine ^a   Horan, Kristy A ^c   Poltajainen, Alina ^b   Østergaard, Lars ^a   Paludan, Søren R ^c   Matikainen, Sampsa ^b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; INTERFERON; NEUTRALIZING ANTIBODY; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; PATTERN RECOGNITION RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; IFIH1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VISA PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSFECTION; HERPES SIMPLEX; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; INNATE IMMUNITY; MACROPHAGE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; VIRUS ACTIVATION; VIRUS ENTRY; VIRUS REPLICATION; BIOSYNTHESIS; CELL CULTURE; IMMUNOLOGY; METABOLISM; SIMPLEXVIRUS; VIROLOGY;

MUS; SIMPLEXVIRUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELLS, CULTURED; CYTOKINES; DEAD-BOX RNA HELICASES; HUMANS; IMMUNITY, INNATE; INTERFERONS; MACROPHAGES; RNA POLYMERASE III; SIGNAL TRANSDUCTION; SIMPLEXVIRUS;

EID: 77957958023     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01106-10     Document Type: Article

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