Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-κB and IRF-3

Journal of General Virology

Volumn 87, Issue 5, 2006, Pages 1099-1108

  Melchjorsen, Jesper ^a,b   Sirén, Jukka ^a   Julkunen, Ilkka ^a   Paludan, Søren R ^b   Matikainen, Sampsa ^a  

^a National Public Institute   (Finland)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMEDIATE EARLY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFECTED CELL PROTEIN 27; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 28; INTERLEUKIN 29; MESSENGER RNA; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS; ULTRAVIOLET RADIATION; VIRUS INACTIVATION; VIRUS REPLICATION; VIRUS RESISTANCE; WILD TYPE;

CYTOKINES; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HERPESVIRUS 1, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERFERON REGULATORY FACTOR-3; INTERFERON-ALPHA; INTERLEUKINS; MACROPHAGES; MUTATION; NF-KAPPA B; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; UBIQUITIN-PROTEIN LIGASES; VIRAL INTERFERENCE; VIRUS REPLICATION;

HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 33646131843     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.81541-0     Document Type: Article

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