A single-nucleotide variation in a p53-binding site affects nutrient-sensitive human SIRT1 expression

Human Molecular Genetics

Volumn 19, Issue 21, 2010, Pages 4123-4133

  Naqvi, Asma ^a   Hoffman, Timothy A ^a   DeRicco, Jeremy ^a   Kumar, Ajay ^a   Kim, Cuk Seong ^a   Jung, Saet Byel ^a   Yamamori, Tohru ^a,e   Kim, Young Rae ^a   Mehdi, Fardeen ^a   Kumar, Santosh ^a   Rankinen, Tuomo ^d   Ravussin, Eric ^d   Irani, Kaikobad ^a,b,c  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^e HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; SIRTUIN 1;

ADULT; ARTICLE; CALORIC RESTRICTION; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; ENERGY EXPENDITURE; EXON; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; GENE DISRUPTION; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MALE; METABOLIC REGULATION; NUTRIENT AVAILABILITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

BINDING SITES; BINDING, COMPETITIVE; CALORIC RESTRICTION; CELL LINE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; SIRTUIN 1; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

MAMMALIA;

EID: 77957881240     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq331     Document Type: Article

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