Androgen Receptor Interacts with the Positive Elongation Factor P-TEFb and Enhances the Efficiency of Transcriptional Elongation

Journal of Biological Chemistry

Volumn 276, Issue 13, 2001, Pages 9978-9984

  Lee, Dong Kun ^a   Duan, Hai Ou ^a   Chang, Chawnshang ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; GENES; HORMONES; RNA; TUMORS;

TRANSCRIPTIONAL ELONGATION;

BIOCHEMISTRY;

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; ANDROGEN RECEPTOR; CYCLIN DEPENDENT KINASE; ELONGATION FACTOR; POSITIVE ELONGATION FACTOR B; POSITIVE ELONGATION FACTOR P; PROSTATE SPECIFIC ANTIGEN; RNA POLYMERASE II; UNCLASSIFIED DRUG; CDK9 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE 9; ENZYME INHIBITOR; LIGAND; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR II; TRANSCRIPTION FACTOR IIH;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME SUBUNIT; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; TRANSACTIVATION; TRANSCRIPTION REGULATION; BIOLOGICAL MODEL; CELL CULTURE; CELL LINE; CELL NUCLEUS; GENETICS; MALE; METABOLISM; MUTATION; PROSTATE TUMOR; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS;

CELL LINE; CELL NUCLEUS; CYCLIN-DEPENDENT KINASE 9; CYCLIN-DEPENDENT KINASES; DICHLORORIBOFURANOSYLBENZIMIDAZOLE; ENZYME INHIBITORS; HUMANS; LIGANDS; MALE; MODELS, BIOLOGICAL; MUTATION; PLASMIDS; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PRECIPITIN TESTS; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANDROGEN; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR TFIIH; TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, TFII; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035971078     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M002285200     Document Type: Article

References (38)

1. Roeder, R. G. (1996) Trends Biochem. Sci. 21, 327-335
2. Goodrich, J. A., and Tjian, R. (1994) Cell 77, 145-156
3. Svejstrup, J. Q., Vichi, P., and Egly, J.-M. (1996) Trends Biochem. Sci. 21, 3346-3350
4. Conaway, J. W., Shilatifard, A., Dvir, A., and Conaway, R. C. (2000) Trends Biochem. Sci. 25, 375-380
5. Beato, M., and Sanchez-Pacheco, A. (1996) Endocr. Rev. 17, 587-609
6. Robyr, D., Wolffe, A. P., and Wahli, W. (2000) Mol. Endocrinol. 14, 329-347
7. Glass, C. K., Rose, D. W., and Rosenfeld, M. G. (1997) Curr. Opin. Cell Biol. 9, 222-232
8. Blau, J., Xia, H., McCracken, S., O'Hare, P., Greenblatt, J., and Bently, D. (1996) Mol. Cll. Biol. 16, 2044-2055
9. Chang, C., Kokontis, J., and Liao, S. T. (1988) Science 240, 324-326
10. Evans, R. M. (1988) Science 240, 889-895
11. Brzozowski, A. M., Pike, A. C. W., Dauter, Z., Hubbard, R. E., Bonn, T., Engstrom, O., Ohman, L., Greene, G. L., Gustafsson, J.-A., and Carlquist, M. (1997) Nature 389, 753-757
12. Williams, S. P., and Sigler, P. B. (1998) Nature 393, 392-396
13. Yeh, S., Miyamoto, H., Nishimura, N., Kang, H., Ludlow, J., Hsiao, P., Wang, C., and Chang, C. (1998) Biochem. Biophys. Res. Commun. 248, 361-357
14. Kang, H. Y., Yeh, S., Fugimoto, N., and Chang, C. (1999) J. Biol. Chem. 274, 8570-8576
15. Fugimoto, N., Yeh, S., Kang, H. Y., Inui, S., Chang, H.-C., Mizokami, A., and Chang, C. (1999) J. Biol. Chem. 274, 8316-8321
16. Hsiao, P.-W., and Chang, C. (1999) J. Biol. Chem. 274, 22373-22379
17. Hsiao, P.-W., Lin, D.-L., Nakao, R., and Chang, C. (1999) J. Biol. Chem. 274, 20229-20234
18. Perlmann, T., and Evans, R. M. (1997) Cell 90, 319-327
19. McEwan, I. J., and Gustafsson, J.-A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 8485-8490
20. Lee, D. K., Duan, H. O., and Chang, C. (2000) J. Biol. Chem. 275, 9308-9313
21. Hadzic, E., Desai-Yajnik, V., Helmer, E., Guo, S., Wu, S., Koudinova, N., Casanova, J., Raaka, B. M., and Samuels, H. H. (1995) Mol. Cell. Biol. 15, 4507-4515
22. Blanco, J., Wang, I., Tsai, S., Tsai, M., O'Malley, B., Jurutka, P., Haussler, M., and Ozato, K. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 1535-1539
23. Malik, S., and Karathanasis, S. K. (1996) Mol. Cell. Biol. 16, 1824-1831
24. Marshall, N. F., and Price, D. H. (1995) J. Biol. Chem. 270, 12335-12338
25. Mancebo, H. S. Y., Lee, G., Flygare, J., Tomassini, J., Luu, P., Zhu, Y., Peng, J., Blau, C., Hazuda, D., Price, D., and Flores, O. (1997) Genes Dev. 11, 2633-2644
26. Yamaguchi, Y., Takgi, T., Wada, T., Yano, K., Furuya, A., Sugimoto, S., Hasegawa, J., and Handa, H. (1999) Cell 97, 41-51
27. Andrews, N. C., and Faller, D. V. (1991) Nucleic Acids Res. 19, 2499
28. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (eds) (1987) Current Protocols in Molecular Biology, Vol. 1, p. 4.10, Wiley Interscience, Cambridge, MA
29. Murphy, S., Yoon, J.-B., Gerster, T., and Roeder, R. G. (1992) Mol. Cell. Biol. 12, 3247-3261
30. Dahmus, M. E. (1996) J. Biol. Chem. 271, 19009-19012
31. Yankulov, K. Y., Panders, M., McCraken, S., Bouchard, D., and Bentley, D. L. (1996) Mol. Cell. Biol. 16, 3291-3299
32. Zhu, Y., Pe'ery, T., Peng, J., Ramaathan, Y., Mashall, N., Marshall, T., Amendt, B., Mathews, M., and Price, D. H. (1997) Genes Dev. 11, 2622-2632
33. Zandomeni, R., and Weinmann, R. (1984) J. Biol. Chem. 259, 14804-14811
34. Fraser, N. W., Sehgal, P. B., and Darnell, J. E. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 2571-2575
35. Tamm, I., and Kikuchi, T. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 5750-5754
36. Uptain, S. M., Kane, C. M., and Chamberlin, M. J. (1997) Annu. Rev. Biochem. 66, 117-172
37. Kelly, J. J., and Wilderman, A. G. (1991) Nucleic Acids Res. 19, 6799-6804
38. Lu, S., Jenster, G., and Epner, D. E. (2000) Mol. Endocrinol. 14, 753-760