Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells

FEBS Letters

Volumn 582, Issue 29, 2008, Pages 4053-4058

  Urano, Emiko ^a,b   Kariya, Yumi ^a   Futahashi, Yuko ^a   Ichikawa, Reiko ^a   Hamatake, Makiko ^a   Fukazawa, Hidesuke ^a   Morikawa, Yuko ^b   Yoshida, Takeshi ^c   Koyanagi, Yoshio ^c   Yamamoto, Naoki ^a   Komano, Jun ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Brd4; cDNA library; HIV 1 replication; Host factor; P TEFb complex; Tat dependent LTR transcription

Indexed keywords

BROMODOMAIN CONTAINING PROTEIN 4; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; COMPLEX FORMATION; CONTROLLED STUDY; DNA LIBRARY; DNA SCREENING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; T LYMPHOCYTE; VIRUS REPLICATION;

BIOLOGICAL ASSAY; CELL LINE; GENE LIBRARY; GENES, REPORTER; HIV INFECTIONS; HIV-1; HUMANS; JURKAT CELLS; LUCIFERASES; NUCLEAR PROTEINS; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN STRUCTURE, TERTIARY; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 56649100549     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.10.047     Document Type: Article

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