메뉴 건너뛰기




Volumn 5, Issue 8, 2010, Pages

Loss of hepatocyte-nuclear-factor-1α impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiation

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; S6 KINASE; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE;

EID: 77957879997     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012378     Document Type: Article
Times cited : (27)

References (43)
  • 1
    • 33646182727 scopus 로고    scopus 로고
    • Organizing cell renewal in the intestine: Stem cells, signals and combinatorial control
    • Crosnier C, Stamataki D, Lewis J (2006) Organizing cell renewal in the intestine: stem cells, signals and combinatorial control. Nat Rev Genet 7: 349-359.
    • (2006) Nat Rev Genet , vol.7 , pp. 349-359
    • Crosnier, C.1    Stamataki, D.2    Lewis, J.3
  • 2
    • 39749092525 scopus 로고    scopus 로고
    • Current view: Intestinal stem cells and signaling
    • Scoville DH, Sato T, He XC, Li L (2008) Current view: intestinal stem cells and signaling. Gastroenterology 134: 849-864.
    • (2008) Gastroenterology , vol.134 , pp. 849-864
    • Scoville, D.H.1    Sato, T.2    He, X.C.3    Li, L.4
  • 3
    • 0002971492 scopus 로고
    • Intestinal Development and Differentiation
    • In: Rustgi AK, ed., Diagnosis, and Therapy Philadelphia: Lippincott-Raven Publishers
    • Traber PG, Wu GD (1995) Intestinal Development and Differentiation. In: Rustgi AK, ed. Gastrointestinal Cancers: Biology, Diagnosis, and Therapy Philadelphia: Lippincott-Raven Publishers. pp 21-43.
    • (1995) Gastrointestinal Cancers: Biology , pp. 21-43
    • Traber, P.G.1    Wu, G.D.2
  • 6
    • 64549114508 scopus 로고    scopus 로고
    • Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2
    • Gao N, White P, Kaestner KH (2009) Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev Cell 16: 588-599.
    • (2009) Dev Cell , vol.16 , pp. 588-599
    • Gao, N.1    White, P.2    Kaestner, K.H.3
  • 7
    • 67650021574 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4{alpha} contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation
    • Babeu JP, Darsigny M, Lussier CR, Boudreau F (2009) Hepatocyte nuclear factor 4{alpha} contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation. Am J Physiol Gastrointest Liver Physiol 297: G124-134.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.297
    • Babeu, J.P.1    Darsigny, M.2    Lussier, C.R.3    Boudreau, F.4
  • 9
    • 77951222415 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium
    • D'Angelo A, Bluteau O, Garcia-Gonzalez MA, Gresh L, Doyen A, et al. (2010) Hepatocyte nuclear factor 1alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium. Development 137: 1573-1582.
    • (2010) Development , vol.137 , pp. 1573-1582
    • D'angelo, A.1    Bluteau, O.2    Garcia-Gonzalez, M.A.3    Gresh, L.4    Doyen, A.5
  • 10
    • 33645893199 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo
    • Bosse T, van Wering HM, Gielen M, Dowling LN, Fialkovich JJ, et al. (2006) Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo. Am J Physiol Gastrointest Liver Physiol 290: G1016-1024.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Bosse, T.1    van Wering, H.M.2    Gielen, M.3    Dowling, L.N.4    Fialkovich, J.J.5
  • 11
    • 0025253275 scopus 로고
    • HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF
    • Baumhueter S, Mendel DB, Conley PB, Kuo CJ, Turk C, et al. (1990) HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF. Genes Dev 4: 372-379.
    • (1990) Genes Dev , vol.4 , pp. 372-379
    • Baumhueter, S.1    Mendel, D.B.2    Conley, P.B.3    Kuo, C.J.4    Turk, C.5
  • 12
    • 0025949056 scopus 로고
    • Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse
    • Blumenfeld M, Maury M, Chouard T, Yaniv M, Condamine H (1991) Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse. Development 113: 589-599.
    • (1991) Development , vol.113 , pp. 589-599
    • Blumenfeld, M.1    Maury, M.2    Chouard, T.3    Yaniv, M.4    Condamine, H.5
  • 13
    • 0030031453 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome
    • Pontoglio M, Barra J, Hadchouel M, Doyen A, Kress C, et al. (1996) Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome. Cell 84: 575-585.
    • (1996) Cell , vol.84 , pp. 575-585
    • Pontoglio, M.1    Barra, J.2    Hadchouel, M.3    Doyen, A.4    Kress, C.5
  • 14
    • 0031944313 scopus 로고    scopus 로고
    • Laron dwarfism and non-insulindependent diabetes mellitus in the Hnf-1alpha knockout mouse
    • Lee YH, Sauer B, Gonzalez FJ (1998) Laron dwarfism and non-insulindependent diabetes mellitus in the Hnf-1alpha knockout mouse. Mol Cell Biol 18: 3059-3068.
    • (1998) Mol Cell Biol , vol.18 , pp. 3059-3068
    • Lee, Y.H.1    Sauer, B.2    Gonzalez, F.J.3
  • 15
    • 18144452590 scopus 로고    scopus 로고
    • Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice
    • Pontoglio M, Sreenan S, Roe M, Pugh W, Ostrega D, et al. (1998) Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. J Clin Invest 101: 2215-2222.
    • (1998) J Clin Invest , vol.101 , pp. 2215-2222
    • Pontoglio, M.1    Sreenan, S.2    Roe, M.3    Pugh, W.4    Ostrega, D.5
  • 16
    • 0037200071 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene
    • Boudreau F, Rings EH, van Wering HM, Kim RK, Swain GP, et al. (2002) Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene. J Biol Chem 277: 31909-31917.
    • (2002) J Biol Chem , vol.277 , pp. 31909-31917
    • Boudreau, F.1    Rings, E.H.2    van Wering, H.M.3    Kim, R.K.4    Swain, G.P.5
  • 18
    • 33846600427 scopus 로고    scopus 로고
    • PTEN-deficient intestinal stem cells initiate intestinal polyposis
    • He XC, Yin T, Grindley JC, Tian Q, Sato T, et al. (2007) PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet 39: 189-198.
    • (2007) Nat Genet , vol.39 , pp. 189-198
    • He, X.C.1    Yin, T.2    Grindley, J.C.3    Tian, Q.4    Sato, T.5
  • 19
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/betacatenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho EH, Zhang T, Domon C, Joo CK, Freund JN, et al. (2002) Wnt/betacatenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 22: 1172-1183.
    • (2002) Mol Cell Biol , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5
  • 20
    • 35548974423 scopus 로고    scopus 로고
    • Identification of stem cells in small intestine and colon by marker gene Lgr5
    • Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, et al. (2007) Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449: 1003-1007.
    • (2007) Nature , vol.449 , pp. 1003-1007
    • Barker, N.1    van Es, J.H.2    Kuipers, J.3    Kujala, P.4    van den Born, M.5
  • 21
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S, Loewith R, Hall MN (2006) TOR signaling in growth and metabolism. Cell 124: 471-484.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 23
    • 38349056675 scopus 로고    scopus 로고
    • Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling
    • DeYoung MP, Horak P, Sofer A, Sgroi D, Ellisen LW (2008) Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling. Genes Dev 22: 239-251.
    • (2008) Genes Dev , vol.22 , pp. 239-251
    • Deyoung, M.P.1    Horak, P.2    Sofer, A.3    Sgroi, D.4    Ellisen, L.W.5
  • 25
    • 33845996593 scopus 로고    scopus 로고
    • Transcriptional regulation of the glucose-6-phosphatase gene by cAMP/vasoactive intestinal peptide in the intestine. Role of HNF4alpha, CREM, HNF1alpha, and C/EBPalpha
    • Gautier-Stein A, Zitoun C, Lalli E, Mithieux G, Rajas F (2006) Transcriptional regulation of the glucose-6-phosphatase gene by cAMP/vasoactive intestinal peptide in the intestine. Role of HNF4alpha, CREM, HNF1alpha, and C/EBPalpha. J Biol Chem 281: 31268-31278.
    • (2006) J Biol Chem , vol.281 , pp. 31268-31278
    • Gautier-Stein, A.1    Zitoun, C.2    Lalli, E.3    Mithieux, G.4    Rajas, F.5
  • 26
    • 0035896576 scopus 로고    scopus 로고
    • A molecular link between the common phenotypes of type 1 glycogen storage disease and HNF1alpha-null mice
    • Hiraiwa H, Pan CJ, Lin B, Akiyama TE, Gonzalez FJ, et al. (2001) A molecular link between the common phenotypes of type 1 glycogen storage disease and HNF1alpha-null mice. J Biol Chem 276: 7963-7967.
    • (2001) J Biol Chem , vol.276 , pp. 7963-7967
    • Hiraiwa, H.1    Pan, C.J.2    Lin, B.3    Akiyama, T.E.4    Gonzalez, F.J.5
  • 27
    • 0021854656 scopus 로고
    • Whole population cell kinetics and postnatal development of the mouse intestinal epithelium
    • Cheng H, Bjerknes M (1985) Whole population cell kinetics and postnatal development of the mouse intestinal epithelium. Anat Rec 211: 420-426.
    • (1985) Anat Rec , vol.211 , pp. 420-426
    • Cheng, H.1    Bjerknes, M.2
  • 28
    • 51649126752 scopus 로고    scopus 로고
    • Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice
    • Fujishita T, Aoki K, Lane HA, Aoki M, Taketo MM (2008) Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice. Proc Natl Acad Sci U S A 105: 13544-13549.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13544-13549
    • Fujishita, T.1    Aoki, K.2    Lane, H.A.3    Aoki, M.4    Taketo, M.M.5
  • 29
    • 67649380840 scopus 로고    scopus 로고
    • Epithelial phosphatase and tensin homolog regulates intestinal architecture and secretory cell commitment and acts as a modifier gene in neoplasia
    • Langlois MJ, Roy SA, Auclair BA, Jones C, Boudreau F, et al. (2009) Epithelial phosphatase and tensin homolog regulates intestinal architecture and secretory cell commitment and acts as a modifier gene in neoplasia. Faseb J 23: 1835-1844.
    • (2009) Faseb J , vol.23 , pp. 1835-1844
    • Langlois, M.J.1    Roy, S.A.2    Auclair, B.A.3    Jones, C.4    Boudreau, F.5
  • 30
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano A, Pandolfi PP (2000) The multiple roles of PTEN in tumor suppression. Cell 100: 387-390.
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Cristofano, A.1    Pandolfi, P.P.2
  • 31
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki K, Zhu T, Guan KL (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell 115: 577-590.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 33
    • 34547576923 scopus 로고    scopus 로고
    • Genetic control of single lumen formation in the zebrafish gut
    • Bagnat M, Cheung ID, Mostov KE, Stainier DY (2007) Genetic control of single lumen formation in the zebrafish gut. Nat Cell Biol 9: 954-960.
    • (2007) Nat Cell Biol , vol.9 , pp. 954-960
    • Bagnat, M.1    Cheung, I.D.2    Mostov, K.E.3    Stainier, D.Y.4
  • 34
    • 0035072875 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism
    • Shih DQ, Bussen M, Sehayek E, Ananthanarayanan M, Shneider BL, et al. (2001) Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism. Nat Genet 27: 375-382.
    • (2001) Nat Genet , vol.27 , pp. 375-382
    • Shih, D.Q.1    Bussen, M.2    Sehayek, E.3    Ananthanarayanan, M.4    Shneider, B.L.5
  • 35
    • 56249135538 scopus 로고    scopus 로고
    • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
    • Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, et al. (2008) A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 456: 259-263.
    • (2008) Nature , vol.456 , pp. 259-263
    • Cadwell, K.1    Liu, J.Y.2    Brown, S.L.3    Miyoshi, H.4    Loh, J.5
  • 36
    • 56249090667 scopus 로고    scopus 로고
    • Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
    • Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, et al. (2008) Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 456: 264-268.
    • (2008) Nature , vol.456 , pp. 264-268
    • Saitoh, T.1    Fujita, N.2    Jang, M.H.3    Uematsu, S.4    Yang, B.G.5
  • 37
    • 0029913505 scopus 로고    scopus 로고
    • Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole
    • Scott SV, Hefner-Gravink A, Morano KA, Noda T, Ohsumi Y, et al. (1996) Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole. Proc Natl Acad Sci U S A 93: 12304-12308.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12304-12308
    • Scott, S.V.1    Hefner-Gravink, A.2    Morano, K.A.3    Noda, T.4    Ohsumi, Y.5
  • 38
    • 0034683568 scopus 로고    scopus 로고
    • Tormediated induction of autophagy via an Apg1 protein kinase complex
    • Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, et al. (2000) Tormediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150: 1507-1513.
    • (2000) J Cell Biol , vol.150 , pp. 1507-1513
    • Kamada, Y.1    Funakoshi, T.2    Shintani, T.3    Nagano, K.4    Ohsumi, M.5
  • 39
    • 70449585192 scopus 로고    scopus 로고
    • Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice
    • Darsigny M, Babeu JP, Dupuis AA, Furth EE, Seidman EG, et al. (2009) Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice. PLoS One 4: e7609.
    • (2009) PLoS One , vol.e7609 , pp. 4
    • Darsigny, M.1    Babeu, J.P.2    Dupuis, A.A.3    Furth, E.E.4    Seidman, E.G.5
  • 41
    • 0035699287 scopus 로고    scopus 로고
    • Characterization of variability in largescale gene expression data: Implications for study design
    • Novak JP, Sladek R, Hudson TJ (2002) Characterization of variability in largescale gene expression data: implications for study design. Genomics 79: 104-113.
    • (2002) Genomics , vol.79 , pp. 104-113
    • Novak, J.P.1    Sladek, R.2    Hudson, T.J.3
  • 42
    • 36949011597 scopus 로고    scopus 로고
    • Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia
    • Boudreau F, Lussier CR, Mongrain S, Darsigny M, Drouin JL, et al. (2007) Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia. Faseb J.
    • (2007) Faseb J
    • Boudreau, F.1    Lussier, C.R.2    Mongrain, S.3    Darsigny, M.4    Drouin, J.L.5
  • 43
    • 24044524492 scopus 로고    scopus 로고
    • Cdk2-dependent phosphorylation of homeobox transcription factor CDX2 regulates its nuclear translocation and proteasome-mediated degradation in human intestinal epithelial cells
    • Boulanger J, Vezina A, Mongrain S, Boudreau F, Perreault N, et al. (2005) Cdk2-dependent phosphorylation of homeobox transcription factor CDX2 regulates its nuclear translocation and proteasome-mediated degradation in human intestinal epithelial cells. J Biol Chem 280: 18095-18107.
    • (2005) J Biol Chem , vol.280 , pp. 18095-18107
    • Boulanger, J.1    Vezina, A.2    Mongrain, S.3    Boudreau, F.4    Perreault, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.