Excitotoxicity through Ca2+-permeable AMPA receptors requires Ca2+-dependent JNK activation

Neurobiology of Disease

Volumn 40, Issue 3, 2010, Pages 645-655

  Vieira, M ^a,b   Fernandes, J ^a,b   Burgeiro, A ^a   Thomas, G M ^c   Huganir, R L ^c   Duarte, C B ^a,d   Carvalho, A L ^a,d   Santos, A E ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

AMPA receptors; AP 1 transcription factor; Calcium channels; Cell death; Excitotoxicity; JNK; Transient global ischemia

Indexed keywords

AMPA RECEPTOR; BINDING PROTEIN; CALCIUM ION; GLUTAMATE RECEPTOR 4; JNK INTERACTING PROTEIN 1; KAINIC ACID; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR STIMULATING AGENT; CALCIUM; MAPK8IP1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL DEATH; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; EXCITOTOXICITY; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; ANIMAL; DRUG EFFECT; GENETIC TRANSFECTION; IMMUNOPRECIPITATION; METABOLISM; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WISTAR RAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, WESTERN; CALCIUM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; EXCITATORY AMINO ACID AGONISTS; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; KAINIC ACID; MALE; MAP KINASE KINASE 4; RATS; RATS, WISTAR; RECEPTORS, AMPA; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 77957795389     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.08.008     Document Type: Article

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