A proteomic analysis of the mechanism of action of naphthoimidazoles in Trypanosoma cruzi epimastigotes in vitro

Journal of Proteomics

Volumn 73, Issue 12, 2010, Pages 2306-2315

  Menna Barreto, Rubem F S ^a   Beghini, Daniela G ^a   Ferreira, André T S ^a   Pinto, Antônio V ^b   De Castro, Solange L ^a   Perales, Jonas ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

lapachone; Chagas' disease; Mass spectrometry; Naphthoimidazoles; Proteomics; Trypanosoma cruzi

Indexed keywords

ANTITRYPANOSOMAL AGENT; CHAPERONE; ERGOSTEROL; IMIDAZOLE DERIVATIVE; NAPHTHOIMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; DRUG MECHANISM; DRUG SYNTHESIS; EPIMASTIGOTE; HOMEOSTASIS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN METABOLISM; PROTEOMICS; TRYPANOSOMA CRUZI;

ANIMALS; CHAGAS DISEASE; DOWN-REGULATION; IMIDAZOLES; NAPHTHOQUINONES; PROTOZOAN PROTEINS; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

PROTOZOA; TRYPANOSOMA CRUZI;

EID: 77957753786     PISSN: 18743919     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jprot.2010.07.002     Document Type: Article

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