Anti-sera raised in rabbits against crotoxin and phospholipase A 2 from Crotalus durissus cascavella venom neutralize the neurotoxicity of the venom and crotoxin

Toxicon

Volumn 44, Issue 2, 2004, Pages 141-148

  Beghini, Daniela G ^a   Hernandez Oliveira, Saraguaci ^a   Rodrigues Simioni, Léa ^a   Novello, José Camilo ^a   Hyslop, Stephen ^a   Marangoni, Sérgio ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Anti serum; Crotapotin; Crotoxin; Neuromuscular blockade; Neutralization; Phospholipase A2

Indexed keywords

ANTISERUM; CROTOXIN; PHOSPHOLIPASE A2; SNAKE VENOM;

ARTICLE; CHICKEN; DIAPHRAGM; DILUTION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR FUNCTION; NEUROTOXICITY; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; ANIMALS; ANTIVENINS; CHICKENS; CROTALID VENOMS; CROTOXIN; MICE; MUSCLE CONTRACTION; MUSCLE, SKELETAL; NEUROMUSCULAR JUNCTION; NEUROTOXINS; PHOSPHOLIPASES A; RABBITS;

CROTALUS; CROTALUS DURISSUS; CROTALUS DURISSUS TERRIFICUS; ORYCTOLAGUS CUNICULUS;

EID: 3042708770     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2004.05.011     Document Type: Article

References (33)

1. Azevedo-Marques M.M., Cupo P., Coimbra T.M., Hering S.E., Rossi M.A., Laure C.J. Myonecrosis, myoglobinuria and acute renal failure induced by South-American rattlesnake (Crotalus durissus terrificus) envenomation in Brazil. Toxicon. 23:1982;631-636
2. 2 from Crotalus durissus cascavella rattlesnake (maracambóia) venom. J. Protein Chem. 19:2000;603-607
3. Bon C., Changeux J.P., Jeng T.W., Fraenkel-Conrat H. Postsynaptic effects of crotoxin and of its isolated subunits. Eur. J. Biochem. 99:1979;471-481
4. 2 and the crotoxin complex. Toxicon. 14:1976;221-233
5. Bülbring E. Observation on the isolated phrenic nerve diaphragm preparation of the rat. Br. J. Pharmacol. 1:1946;38-61
6. 2 isolated from Crotalus durissus sp. in the rat dorsal skin: a role for mast cells and sensory C-fibers. Toxicon. 41:2003;823-829
7. Chavez-Olórtegui C., Silva Lopes C., Drumond Cordeiro F., Granier C., Diniz C.R. An enzyme linked immunosorbent assay (ELISA) that discriminates between Bothrops atrox and Lachesis muta muta venoms. Toxicon. 31:1993;417-425
8. 2 neurotoxin, crotoxin, by non-precipitating antibodies (Fab). FEBS Lett. 244:1989;167-173
9. 2 neurotoxin, crotoxin, with monoclonal antibodies. Mol. Immunol. 29:1992;871-882
10. 2 neurotoxin, crotoxin, neutralizes its toxicity. J. Biol. Chem. 379:1998;899-906
11. 2 injection in mice induces immunity against the lethal effects of Crotalus durissus terrificus venom. Toxicon. 26:1988;207-213
12. Faure G., Harvey A.L., Thomson E., Saliou B., Radvani F., Bon C. Comparison of crotoxin isoforms reveals that stability of the complex plays a major role in its pharmacological action. Eur. J. Biochem. 214:1993;491-496
13. Freitas T.V., Fortes-Dias C.L., Diniz C.R. Protection against the lethal effects of Crotalus durissus terrificus (South American rattlesnake) venom in animals immunized with crotoxin. Toxicon. 28:1990;1491-1496
14. Ginsborg B.L., Warriner J. The isolated chick biventer cervicis nerve muscle preparation. Br. J. Pharmacol. 15:1960;410-411
15. Hendon R.A., Fraenkel-Conrat H. Biological roles of the two components of crotoxin. Proc. Natl Acad. Sci. USA. 68:1971;1560-1563
16. Jeng T.W., Hendon R.A., Fraenkel-Conrat H. Search for relationship among the hemolytic, phospholipolytic and neurotoxic activities of snake venoms. Proc. Natl Acad. Sci. USA. 75:1978;600-604
17. Landucci E.C., Condino-Neto A., Perez A.C., Hyslop S., Corrado A.P., Novello J.C., Marangoni S., Oliveira B., Antunes E., De Nucci G. Crotoxin induces aggregation of human washed platelets. Toxicon. 32:1994;217-226
18. Lomonte B., Gutiérrez J.M., Moreno E., Cerdas L. Antibody neutralization of a myotoxin from the venom of Bothrops asper (terciopelo). Toxicon. 25:1987;443-449
19. Marlas G. Purification and preliminary structure of a potent platelet aggregating glycoprotein isolated from the venom of Crotalus durissus cascavella. Toxicon. 20:1982;289-290
20. Marlas G. Isolation and characterization of the alpha and beta subunits of the platelet-activating glycoprotein from the venom of Crotalus durissus cascavella. Biochimie. 67:1985;1232-1239
21. Marlas G., Bon C. Relationship between the pharmacological action of crotoxin and its phospholipase activity. Eur. J. Biochem. 125:1982;157-165
22. Marlas G., Joseph D., Huet C. I-isolation and electron microscope studies of a potent platelet-aggregating glycoprotein from the venom of Crotalus durissus cascavella. Biochimie. 65:1983;405-416
23. Marlas G., Joseph D., Huet C. Subunit structure of a potent platelet-activating glycoprotein isolated from the venom of Crotalus durissus cascavella. Biochimie. 65:1983;619-628
24. Martins A.M., Monteiro H.S., Júnior E.O., Menezes D.B., Fonteles M.C. Effects of Crotalus durissus cascavella venom in the isolated rat kidney. Toxicon. 36:1998;1441-1450
25. Martins A.M., Toyama M.H., Havt A., Novello J.C., Marangoni S., Fonteles M.C., Monteiro H.S. Determination of Crotalus durissus cascavella venom components that induce renal toxicity in isolated rat kidneys. Toxicon. 40:2002;1165-1171
26. 2 and cyclooxygenase. Pharmacol. Toxicol. 92:2003;14-20
27. Oliveira D.G., Toyama M.H., Martins A.M., Havt A., Nobre A.C., Marangoni S., Câmara P.R., Antunes E., de Nucci G., Beliam L.O., Fonteles M.C., Monteiro H.S. Structural and biological characterization of a crotapotin isoform isolated from Crotalus durissus cascavella venom. Toxicon. 42:2003;53-62
28. Oshima-Franco Y., Hyslop S., Prado-Franceschi J., Cruz-Höfling M.A., Rodrigues-Simioni L. Neutralizing capacity of antisera raised in horses and rabbits against Crotalus durissus terrificus (South American rattlesnake) venom and its main toxin, crotoxin. Toxicon. 37:1999;1341-1457
29. Ouchterlony O. Antigen-antibody reactions in gels. Acta Path. Microbiol. Scand. 26:1949;507-515
30. Rosenfeld G. Symptomatology, pathology and treatment of snake bites in South America. Bücherl W., Buckley E.E. Venomous Animals and their Venoms. vol. 2:1971;345-384 Academic Press, New York
31. Santoro M.L., Sousa-e-Silva M.C.C., Gonçalvez L.R.C., Almeida-Santos S.M., Cardoso D.F., Laporta-Ferreira I.L., Saiki M., Peres C.A., Sano-Martins I.S. Comparison of the biological activities in venoms from three subspecies of the South American rattlesnake (Crotalus durissus terrificus, C. durissus cascavella and C. durissus collilineatus). Comp. Biochem. Physiol. Part C. 122:1999;61-73
32. Slotta K.H., Fraenkel-Conrat H.L. Schlangengifte, III: Mitteilung Reiningung und Krystallization des Klapperschangengiftes. Ber. Dich. Chem. Ges. 71:1938;1076-1081
33. Vital Brazil O. Pharmacology of crystalline crotoxin. II. Neuromuscular blocking action. Mem. Inst. Butantan. 33:1966;981-992