Effect of a β-lapachone-derived naphthoimidazole on Trypanosoma cruzi: Identification of target organelles

Journal of Antimicrobial Chemotherapy

Volumn 56, Issue 6, 2005, Pages 1034-1041

  Menna Barreto, Rubem F S ^a   Henriques Pons, Andrea ^a   Pinto, Antônio V ^b   Morgado Diaz, José A ^c   Soares, Maurilio J ^a   De Castro, Solange L ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

Chemotherapy; Naphthoquinones; Parasites; T. cruzi

Indexed keywords

ACRIDINE ORANGE; BENZALDEHYDE; BETA LAPACHONE; DIMETHYL SULFOXIDE; IMIDAZOLE DERIVATIVE; NAPHTHOIMIDAZOLE; NAPHTHOQUINONE; POLYPHOSPHATE; RHODAMINE 123; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL ENERGY; CELL NUCLEUS; CELL ORGANELLE; CHROMATIN CONDENSATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ELECTRON MICROSCOPY; EMBRYO; ENZYME INHIBITION; EPIMASTIGOTE; FLOW CYTOMETRY; HEART MUSCLE CELL; MACROPHAGE; MITOCHONDRION; MOUSE; NONHUMAN; TABEBUIA; TARGET CELL; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

ACRIDINE ORANGE; ANIMALS; BENZALDEHYDES; CELLS, CULTURED; CHROMATIN; CYTOPLASMIC GRANULES; IMIDAZOLES; MACROPHAGES, PERITONEAL; MICE; MICROSCOPY, ELECTRON; MITOCHONDRIA; MYOCYTES, CARDIAC; NAPHTHOQUINONES; ORGANELLES; RHODAMINE 123; SUCCINATE CYTOCHROME C OXIDOREDUCTASE; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 29444438029     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dki403     Document Type: Article

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