Na+-ATPase and protein kinase C are targets to 1-O-hexadecylphosphocoline (miltefosine) in Trypanosoma cruzi

Archives of Biochemistry and Biophysics

Volumn 481, Issue 1, 2009, Pages 65-71

  Saraiva, Victor Barbosa ^a   Wengert, Mira ^a   Gomes Quintana, Elaine ^a   Heise, Norton ^a   Caruso Neves, Celso ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Chagas disease; Ether lipid analogue; Na+ ATPase; Parasite growth inhibition; PKC; Trypanosoma cruzi

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM ION; EGTAZIC ACID; FUROSEMIDE; MEMBRANE PHOSPHOLIPID; MILTEFOSINE; PROTEIN KINASE C;

ARTICLE; CHAGAS DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; EPIMASTIGOTE; GROWTH INHIBITION; NONHUMAN; PARASITE; PRIORITY JOURNAL; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS;

ANIMALS; CALCIUM; CELL MEMBRANE; FUROSEMIDE; HYDROGEN-ION CONCENTRATION; KINETICS; PHOSPHORYLCHOLINE; PROTEIN KINASE C; SODIUM-POTASSIUM-EXCHANGING ATPASE; SWINE; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 57649089364     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2008.10.018     Document Type: Article

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