Label-free screening of drug-protein interactions by time-resolved Fourier transform infrared spectroscopic assays exemplified by Ras interactions

Applied Spectroscopy

Volumn 64, Issue 9, 2010, Pages 967-972

  Rötting, Carsten ^a   Suveyzdis, Yan ^a   Bojja, Ravi S ^a   Metzler Nolte, Nils ^a   Gerwert, Klaus ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Anticancer activity; FT IR spectroscopy; GTPase; High throughput; Label free; Metal macrocycles; Protein interactions; Screening; Time resolved Fourier transform infrared spectroscopy

Indexed keywords

DISEASES; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROLYSIS; MOLECULES; SCREENING; SIGNAL TRANSDUCTION; SPACECRAFT INSTRUMENTS; THROUGHPUT;

ANTICANCER ACTIVITIES; FTIR SPECTROSCOPY; GTPASE; HIGH THROUGHPUT; LABEL FREE; MACROCYCLES; PROTEIN INTERACTION; TIME-RESOLVED FOURIER TRANSFORM INFRARED SPECTROSCOPIES;

PROTEINS;

EID: 77957686511     PISSN: 00037028     EISSN: None     Source Type: Journal    
DOI: 10.1366/000370210792434341     Document Type: Article

References (40)

1. C. Kötting and K. Gerwert, Chem Phys Chem 6, 881 (2005).
2. K. Gerwert, B. Hess, J. Soppa, and D. Oesterhelt, Proc. Nat. Acad. Sci. U. S. A. 86, 4943 (1989).
3. J. Downward, Nat. Rev. Cancer 3, 11 (2003).
4. K. Wennerberg, K. L. Rossman, and C. J. Der, J. Cell. Sci. 118, 843 (2005).
5. J. L. Bos, H. Rehmann, and A. Wittinghofer, Cell 129, 865 (2007).
6. C. Herrmann, Curr. Opin. Struct. Biol. 13, 122 (2003).
7. K. Scheffzek, M. R. Ahmadian, W. Kabsch, L. Wiesmuller, A. Lautwein, F. Schmitz, and A. Wittinghofer, Science (Washington, D. C.) 277, 333 (1997).
8. I. R. Vetter and A. Wittinghofer, Science (Washington, D. C.) 294, 1299 (2001).
9. M. Spoerner, C. Herrmann, I. R. Vetter, H. R. Kalbitzer, and A. Wittinghofer, Proc. Nat. Acad. Sci. U. S. A. 98, 4944 (2001).
10. C. Kotting, M. Blessenohl, Y. Suveyzdis, R. Goody, A. Wittinghofer, and K. Gerwert, Proc. Nat. Acad. Sci. U. S. A. 103, 13911 (2006).
11. C. Kötting, A. Kallenbach, Y. Suveyzdis, A. Wittinghofer, and K. Gerwert, Proc. Nat. Acad. Sci. U. S. A. 105, 6260 (2008).
12. C. Kötting, A. Kallenbach, Y. Suveyzdis, C. Eichholz, and K. Gerwert, Chem Bio Chem 8, 781 (2007).
13. S. Schubbert, K. Shannon, and G. Bollag, Nat. Rev. Cancer 7, 295 (2007).
14. M. R. Ahmadian, Brit. J. Haematol. 116, 511 (2002).
15. D. Strumberg and S. Seeber, Onkologie 28, 101 (2005).
16. A. Wittinghofer and H. Waldmann, Angew. Chem. Int. Ed. Engl. 39, 4192 (2000).
17. H. te Heesen, A. M. Schlitter, and J. Schlitter, J. Mol. Graph. 25, 671 (2007).
18. J. Kato-Stankiewicz, I. Hakimi, G. Zhi, J. Zhang, I. Serebriiskii, L. Guo, H. Edamatsu, H. Koide, S. Menon, R. Eckl, S. Sakamuri, Y. C. Lu, Q. Z. Chen, S. Agarwal, W. R. Baumbach, E. A. Golemis, F. Tamanoi, and V. Khazak, Proc. Nat. Acad. Sci. U. S. A. 99, 14398 (2002).
19. M. Spoemer, T. Graf, B. Koenig, and H. R. Kalbitzer, Biochem. Biophys. Res. Commun. 334, 709 (2005).
20. J. Tucker, G. Sczakiel, J. Feuerstein, J. John, R. S. Goody, and A. Wittinghofer, EM BO J. 5, 1351 (1986).
21. M. R. Ahmadian, U. Hoffmann, R. S. Goody, and A. Wittinghofer, Biochemistry 36, 4535 (1997).
22. P. P. Chakrabarti, O. Daumke, Y. Suveyzdis, C. Kotting, K. Gerwert, and A. Wittinghofer, J. Mol. Biol. 367, 983 (2007).
23. C. Herrmann, G. A. Martin, and A. Wittinghofer, J. Biol. Chem. 270, 2901 (1995).
24. J. Walker, G. P. Reid, J. A. McCray, and D. R. Trentham, J. Am. Chem. Soc. 110, 7170 (1988).
25. C.-H. Park and R. S. Givens, J. Am. Chem. Soc. 119, 2453 (1997).
26. S. I. Kirin, P. Dubon, T. Weyhermuller, E. Bill, and N. Metzler-Nolte, Inorg. Chem. 44, 5405 (2005).
27. S. I. Kirin, F. Noor, N. Metzler-Nolte, and W. Mier, J. Chem. Educ. 84, 108 (2007).
28. N. Metzler-Nolte, Chimia 61, 736 (2007).
29. F. Noor, R. Kinscherf, G. A. Bonaterra, S. Walczak, S. Wolfl, and N. Metzler-Nolte, Chem Bio Chem 10, 493 (2009).
30. J. John, R. Sohmen, J. Feuerstein, R. Linke, A. Wittinghofer, and R. S. Goody, Biochemistry 29, 6058 (1990).
31. V. Cepus, A. J. Scheidig, R. S. Goody, and K. Gerwert, Biochemistry 37, 10263 (1998).
32. K. Gerwert, G. Souvignier, and B. Hess, Proc. Nat. Acad. Sci. U. S. A. 87, 9774 (1990).
33. B. Hessling, G. Souvignier, and K. Gerwert, Biophys. J. 65, 1929 (1993).
34. C. Kotting and K. Gerwert, Chem. Phys. 307, 227 (2004).
35. A. J. Scheidig, S. M. Franken, J. E. Corrie, G. P. Reid, A. Wittinghofer, E. F. Pai, and R. S. Goody, J. Mol. Biol. 253, 132 (1995).
36. C. Allin and K. Gerwert, Biochemistry 40, 3037 (2001).
37. B. Warscheid, S. Brucker, A. Kallenbach, H. E. Meyer, K. Gerwert, and C. Kötting, Vib. Spectrosc. 48, 28 (2008).
38. M. Saleem, S. Kaur, M. H. Kweon, V. M. Adhami, F. Afaq, and H. Mukhtar, Carcinogenesis 26, 1956 (2005).
39. H. te Heesen, K. Gerwert, and J. Schlitter, FEBS Lett. 581, 5677 (2007).
40. B. Sot, C. Kotting, D. Deaconsescu, Y. Suveyzdis, K. Gerwert, and A. Wittinghofer, EMBO J. 29, 1205 (2010).