Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the β-phosphate

Biochemistry

Volumn 37, Issue 28, 1998, Pages 10263-10271

  Cepus, V ^a   Scheidig, A J ^b   Goody, R S ^b   Gerwert, K ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; PROTEIN P21;

ARTICLE; CHEMICAL BOND; ENZYME MECHANISM; INFRARED SPECTROSCOPY; ONCOGENE RAS; PHOTOLYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REACTION ANALYSIS; STRUCTURE ANALYSIS;

CRYSTALLOGRAPHY, X-RAY; GTP PHOSPHOHYDROLASES; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMANS; MAGNESIUM; MOLECULAR STRUCTURE; PHOSPHATES; PHOTOLYSIS; PROTO-ONCOGENE PROTEINS P21(RAS); SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THIONUCLEOTIDES;

EID: 0032516479     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi973183j     Document Type: Article

References (45)

1. McCormick, F. (1993) Nature 363, 15-16.
2. Li, N., Batzer, A., Yajnik, V., Skolnik, E., Chardin, P., Bar-Sagi, D., Margolis, B., and Schlessinger, J. (1993) Nature 363, 85-88.
3. Wiesmüller, L., and Wittinghofer, F. (1994) Cell. Signalling 6, 247-267.
4. John, J., Schlichting, I., Schiltz, E., Rösch, P., and Wittinghofer, A. (1989) J. Am. Chem. Soc. 264, 13086-13092.
5. Bourne, H. R., Sanders, D. W., and McCormick, F. (1990) Nature 348, 125-132.
6. Lowy, D. R., and Willumsen, B. M. (1993) Annu. Rev. Biochem. 62, 851-891.
7. Gideon, P., John, J., Frech, M., Lautwein, A., Clark, R., Scheffler, J. E., and Wittinghofer, A. (1992) Mol. Cell. Biol. 12, 2050-2056.
8. Der, D., Finkel, T., and Cooper, G. M. (1986) Cell 44, 167-176.
9. Barbacid, M. (1987) Annu. Rev. Biochem. 56, 779-827.
10. Levitzki, A. (1994) Eur. J. Biochem. 226, 1-13.
11. Pai, E. F., Kabsch, W., Krengel, U., Holmes, K. C., John, J., and Wittinghofer, A. (1989) Nature 341, 209-214.
12. Pai, E. F., Krengel, U., Petsko, G. A., Goody, R. S., Kabsch, W., and Wittinghofer, A. (1990) EMBO J. 9, 2351-2359.
13. Wittinghofer, A., and Pai, E. F. (1991) Trends Biochem. Sci. 16, 382-386.
14. Frech, M., Darden, T. A., Pedersen, L. G., Foley, C. K., Charifson, P. S., Anderson, M. W., and Wittinghofer, A. (1994) Biochemistry 33, 3237-3244.
15. Chung, H.-H., Benson, D. R., and Schultz, P. G. (1991) Science 259, 806-809.
16. Schweins, T., Geyer, M., Scheffzek, K., Warshel, A., Kalbitzer, H. R., and Wittinghofer, A. (1995) Nat. Struct. Biol. 2, 36-44.
17. Scheffzek, K., Ahmadian, M. R., Kabsch, W., Wiesmüller, L., Lautwein, A., Schmitz, F., and Wittinghofer, A. (1997) Science 277, 333-338.
18. Rittinger, K., Walker, P. A., Eccleston, J. F., Smerdon, S. J., and Gamblin, S. J. (1997) Nature 389, 758-762.
19. Sondek, J., Lambright, D. G., Noel, J. P., Hamm, H. E., and Sigler, P. B. (1994) Nature 372, 276-279.
20. Coleman, D. E., Berghuis, A. M., Lee, E., Linder, M. E., Gilman, A. G., and Sprang, S. R. (1994) Science 265, 1405-1412.
21. Maegley, K. A., Admiraal, S. J., and Herschlag, D. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 8160-8166.
22. Gerwert, K. (1993) Biochim. Biophys. Acta 1101, 147-153.
23. Gerwert, K., Souvignier, G., and Hess, B. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 9774-9778.
24. Brudler, R., de Groot, H. J. M., van Liemt, W. B. S., Steggerda, W. F., Esmeijer, R., Gast, P., Hoff, A. J., Lugtenburg, J., Gerwert, K. (1994) EMBO J. 13, 5523-5530.
25. Gerwert, K., Cepus, V., Scheidig, A., and Goody, R. S. (1994) in Time-Resolved Vibrational Spectroscope VI (Lau, A., Siebert, F., and Werncke, W., Eds.) pp 185-187, Springer-Verlag, Berlin, Heidelberg.
26. Schlichting, I., Rapp, G., John, J., Wittinghofer, A., Pai, E. F., and Goody, R. S. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 7687-7690.
27. Schlichting, I., Almo, S. C., Rapp, G., Wilson, K., Petratos, K., Lentfer, A., Wittinghofer, A., Kabsch, W., Pai, E. F., Petsko, G. A., and Goody, R. S. (1990) Nature 345, 309-315.
28. Walker, J., Reid, G. P., McCray, J. A., and Trentham, D. R. (1988) J. Am. Chem. Soc. 110, 7170-7177.
29. Kalbitzer, H. R., Feuerstein, J., Goody, R. S., and Wittinghofer, A. (1990) Eur. J. Biochem. 188, 355-359.
30. John, J., Sohmen, R., Feuerstein, J., Linke, R., Wittinghofer, A., and Goody, R. S. (1990) Biochemistry 29, 6058-6065.
31. Gerwert, K, Souvignier, G., and Hess, B. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 9774-9778.
32. Hessling, B., Herbst, J., Rammelsberg, R., and Gerwert, K. (1997) Biophys. J. 73, 2071-2080.
33. Cepus, V., Allin, C., Ulbrich, C., Troullier, A., and Gerwert, K. (1998) in Methods in Enzymology, Vol. 291 (Mariott, G., Ed.) pp 223-245, Academic Press, San Diego.
34. Barth, A., Hauser, K., Mäntele, W., Corrie, J. E. T., and Trentham, D. R. (1995) J. Am. Chem. Soc. 117, 10311-10316.
35. Colthup, N. B., Daly, L. H., and Wiberley, S. E. (1990) Introduction to Infrared and Roman Spectroscopy, Academic Press, San Diego. Inc.
36. Scheidig, A. J., Franken, S. M., Corrie, J. E. T., Reid, G. P., Wittinghofer, A., Pai, E. F., and Goody, R. S. (1995) J. Mol. Biol. 253, 132-150.
37. Krengel, U., Schlichting, I., Scherer, A., Schumann, R., Frech, M., John, J., Kabsch, W., Pai, E. F., and Wittinghofer, A. (1990) Cell 62, 539-548.
38. Schweins, T., Geyer, M., Kalbitzer, H. R., Wittinghofer, A., and Warshel, A. (1996) Biochemistry 35, 14225-14231.
39. Chapman, A. C., and Thirlwell, L. E. (1964) Spectrochim. Acta 20, 937-947.
40. Takeuchi, H., Murata, H., and Harada, I. (1988) J. Am. Chem. Soc. 110, 392-397.
41. Milburn, M. V., Tong, L., de Vos, A. M., Brünger, A., Yamaizumi, Z., Nishimura, S., and Kim, S.-H. (1990) Science 247, 939-945.
42. Farrar, C. T., Halkides, C. J., and Singel, D. J. (1997) Structure 5, 1055-1066.
43. Feuerstein, J., Kalbitzer, H. R., John, J., Goody, R. S., and Wittinghofer, A. (1987) Eur. J. Biochem. 162, 49-55.
44. Tong, L., de Vos, A. M., Milburn, M. V., and Kim, S.-H. (1991) J. Mol. Biol. 217, 503-516.
45. le Coutre, J., Tittor, J., Oesterhelt, D., and Gerwert, K. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 4962-4966.