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Volumn 177, Issue 4, 2010, Pages 1834-1847

Peroxisome proliferator-activated receptor δ regulates inflammation via NF-κB signaling in polymicrobial sepsis

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; TUMOR NECROSIS FACTOR ALPHA;

EID: 77957348621     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.091010     Document Type: Article
Times cited : (70)

References (42)
  • 1
    • 34250890817 scopus 로고    scopus 로고
    • Pathophysiology of sepsis
    • Remick DG: Pathophysiology of sepsis. Am J Pathol 2007, 170:1435-1444
    • (2007) Am J Pathol , vol.170 , pp. 1435-1444
    • Remick, D.G.1
  • 2
    • 0033975869 scopus 로고    scopus 로고
    • Innate immune recognition: Mechanisms and pathways
    • Medzhitov R, Janeway C Jr: Innate immune recognition: mechanisms and pathways. Immunol Rev 2000, 173:89-97
    • (2000) Immunol Rev , vol.173 , pp. 89-97
    • Medzhitov, R.1    Janeway Jr., C.2
  • 3
    • 0032217267 scopus 로고    scopus 로고
    • IκB-NF-κB structures: At the interface of inflammation control
    • Baeuerle PA: IκB-NF-κB structures: at the interface of inflammation control. Cell 1998, 11:729-731
    • (1998) Cell , vol.11 , pp. 729-731
    • Baeuerle, P.A.1
  • 4
    • 0037247748 scopus 로고    scopus 로고
    • Nuclear factor-κB as a therapeutic target in critical care medicine
    • Zingarelli B, Sheehan M, Wong HR: Nuclear factor-κB as a therapeutic target in critical care medicine. Crit Care Med 2003, 31:S105-S111
    • (2003) Crit Care Med , vol.31
    • Zingarelli, B.1    Sheehan, M.2    Wong, H.R.3
  • 5
    • 33846623798 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets
    • Brown JD, Plutzky J: Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets. Circulation 2007, 115:518-533
    • (2007) Circulation , vol.115 , pp. 518-533
    • Brown, J.D.1    Plutzky, J.2
  • 6
    • 68449095060 scopus 로고    scopus 로고
    • PPARδ in humans: Genetic and pharmacological evidence for a significant metabolic function
    • Karpe F, Ehrenborg EE: PPARδ in humans: genetic and pharmacological evidence for a significant metabolic function. Curr Opin Lipidol 2009, 20:333-336
    • (2009) Curr Opin Lipidol , vol.20 , pp. 333-336
    • Karpe, F.1    Ehrenborg, E.E.2
  • 10
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity
    • Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM: Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity. Cell 2003, 113:159-170
    • (2003) Cell , vol.113 , pp. 159-170
    • Wang, Y.X.1    Lee, C.H.2    Tiep, S.3    Yu, R.T.4    Ham, J.5    Kang, H.6    Evans, R.M.7
  • 11
    • 33644652740 scopus 로고    scopus 로고
    • Involvement of PPAR nuclear receptors in tissue injury and wound repair
    • Michalik L, Wahli W: Involvement of PPAR nuclear receptors in tissue injury and wound repair. J Clin Invest 2006, 116:598-606
    • (2006) J Clin Invest , vol.116 , pp. 598-606
    • Michalik, L.1    Wahli, W.2
  • 14
    • 33744519163 scopus 로고    scopus 로고
    • PPARδ modulates lipopolysaccharide-induced TNFα inflammation signaling in cultured cardiomyocytes
    • Ding G, Cheng L, Qin Q, Frontin S, Yang Q: PPARδ modulates lipopolysaccharide-induced TNFα inflammation signaling in cultured cardiomyocytes. J Mol Cell Cardiol 2006, 40:821-828
    • (2006) J Mol Cell Cardiol , vol.40 , pp. 821-828
    • Ding, G.1    Cheng, L.2    Qin, Q.3    Frontin, S.4    Yang, Q.5
  • 16
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • Dent AL, Shaffer AL, Yu X, Allman D, Staudt LM: Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 1997, 276:589-592
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 17
    • 0346366979 scopus 로고    scopus 로고
    • 12,14-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways
    • 12,14-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways. J Immunol 2003, 171:6827-6837
    • (2003) J Immunol , vol.171 , pp. 6827-6837
    • Zingarelli, B.1    Sheehan, M.2    Hake, P.W.3    O'Connor, M.4    Denenberg, A.5    Cook, J.A.6
  • 19
    • 0032032469 scopus 로고    scopus 로고
    • Sulfasalazine: A potent and specific inhibitor of nuclear factor kappa B
    • Wahl C, Liptay S, Adler G, Schmid RM: Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J Clin Invest 1998, 101:1163-1174
    • (1998) J Clin Invest , vol.101 , pp. 1163-1174
    • Wahl, C.1    Liptay, S.2    Adler, G.3    Schmid, R.M.4
  • 20
    • 33845905763 scopus 로고    scopus 로고
    • The disconnect between animal models of sepsis and human sepsis
    • Rittirsch D, Hoesel LM, Ward PA: The disconnect between animal models of sepsis and human sepsis. J Leukoc Biol 2007, 81:137-143
    • (2007) J Leukoc Biol , vol.81 , pp. 137-143
    • Rittirsch, D.1    Hoesel, L.M.2    Ward, P.A.3
  • 22
    • 0033625677 scopus 로고    scopus 로고
    • Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator- activated receptor β(δ)
    • Peters JM, Lee SS, Li W, War JM, Gavrilova O, Everett C, Reitman ML, Hudson LD, Gonzalez FJ: Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator- activated receptor β(δ). Mol Cell Biol 2000, 20:5119-5128
    • (2000) Mol Cell Biol , vol.20 , pp. 5119-5128
    • Peters, J.M.1    Lee, S.S.2    Li, W.3    War, J.M.4    Gavrilova, O.5    Everett, C.6    Reitman, M.L.7    Hudson, L.D.8    Gonzalez, F.J.9
  • 23
    • 0030771852 scopus 로고    scopus 로고
    • DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. Importance of the 5′-flanking region
    • Juge-Aubry C, Pernin A, Favez T, Burger AG, Wahli W, Meier CA, Desvergne B: DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. Importance of the 5′-flanking region. J Biol Chem 1997, 272:25252-25259
    • (1997) J Biol Chem , vol.272 , pp. 25252-25259
    • Juge-Aubry, C.1    Pernin, A.2    Favez, T.3    Burger, A.G.4    Wahli, W.5    Meier, C.A.6    Desvergne, B.7
  • 24
    • 0025789094 scopus 로고
    • Enhancers and transcription factors controlling the inducibility of the tumor necrosis factor-α promoter in primary macrophages
    • Drouet C, Shakhov AN, Jongeneel CV: Enhancers and transcription factors controlling the inducibility of the tumor necrosis factor-α promoter in primary macrophages. J Immunol 1991, 147:1694-1700
    • (1991) J Immunol , vol.147 , pp. 1694-1700
    • Drouet, C.1    Shakhov, A.N.2    Jongeneel, C.V.3
  • 25
    • 33846174641 scopus 로고    scopus 로고
    • Tumor necrosis factor and interleukin 1 decrease RXRα. PPARα, PPARγ, LXRα, and the coactivators SRC-1, PGC-1α, and PGC-1β in liver cells
    • Kim MS, Sweeney TR, Shigenaga JK, Chui LG, Moser A, Grunfeld C, Feingold KR: Tumor necrosis factor and interleukin 1 decrease RXRα. PPARα, PPARγ, LXRα, and the coactivators SRC-1, PGC-1α, and PGC-1β in liver cells. Metabolism 2007, 256:267-279
    • (2007) Metabolism , vol.256 , pp. 267-279
    • Kim, M.S.1    Sweeney, T.R.2    Shigenaga, J.K.3    Chui, L.G.4    Moser, A.5    Grunfeld, C.6    Feingold, K.R.7
  • 26
    • 0942287345 scopus 로고    scopus 로고
    • Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response
    • Feingold K, Kim MS, Shigenaga J, Moser A, Grunfeld C: Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response. Am J Physiol Endocrinol Metab 2004, 286:E201-E207
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Feingold, K.1    Kim, M.S.2    Shigenaga, J.3    Moser, A.4    Grunfeld, C.5
  • 27
    • 0037207510 scopus 로고    scopus 로고
    • TNFα downregulates PPARδ expression in oligodendrocyte progenitor cells: Implications for demyelinating diseases
    • Cimini A, Bernardo A, Cifone MG, Di Marzio L, Di Loreto S: TNFα downregulates PPARδ expression in oligodendrocyte progenitor cells: implications for demyelinating diseases. Glia 2003, 41:3-14
    • (2003) Glia , vol.41 , pp. 3-14
    • Cimini, A.1    Bernardo, A.2    Cifone, M.G.3    Di Marzio, L.4    Di Loreto, S.5
  • 31
    • 0038460253 scopus 로고    scopus 로고
    • PPARγ and PPARδ negatively regulate specific subsets of lipopolysaccharide and IFN-γ target genes in macrophages
    • Welch JS, Ricote M, Akiyama TE, Gonzalez FJ, Glass CK: PPARγ and PPARδ negatively regulate specific subsets of lipopolysaccharide and IFN-γ target genes in macrophages. Proc Natl Acad Sci USA 2003, 100:6712-6717
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 6712-6717
    • Welch, J.S.1    Ricote, M.2    Akiyama, T.E.3    Gonzalez, F.J.4    Glass, C.K.5
  • 32
    • 0042140583 scopus 로고    scopus 로고
    • Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis
    • Sheehan M, Wong HR, Hake PW, Zingarelli B: Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis. Crit Care Med 2003, 31:2263-2270
    • (2003) Crit Care Med , vol.31 , pp. 2263-2270
    • Sheehan, M.1    Wong, H.R.2    Hake, P.W.3    Zingarelli, B.4
  • 34
    • 0034113383 scopus 로고    scopus 로고
    • Increased nuclear factor κB activation in critically ill patients who die
    • Paterson RL, Galley HF, Dhillon JK, Webster NR: Increased nuclear factor κB activation in critically ill patients who die. Crit Care Med 2000, 28:1047-1051
    • (2000) Crit Care Med , vol.28 , pp. 1047-1051
    • Paterson, R.L.1    Galley, H.F.2    Dhillon, J.K.3    Webster, N.R.4
  • 36
    • 0037022592 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor δ, an integrator of transcriptional repression and nuclear receptor signaling
    • Shi Y, Hon M, Evans RM: The peroxisome proliferator-activated receptor δ, an integrator of transcriptional repression and nuclear receptor signaling. Proc Natl Acad Sci USA 2002, 99:2613-2618
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2613-2618
    • Shi, Y.1    Hon, M.2    Evans, R.M.3
  • 37
  • 38
    • 0030858764 scopus 로고    scopus 로고
    • Lipopolysaccharide induction of the tumor necrosis factor-α promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-κB transcription factors
    • Yao J, Mackman N, Edgington TS, Fan ST: Lipopolysaccharide induction of the tumor necrosis factor-α promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-κB transcription factors. J Biol Chem 1997, 272:17795-17801
    • (1997) J Biol Chem , vol.272 , pp. 17795-17801
    • Yao, J.1    Mackman, N.2    Edgington, T.S.3    Fan, S.T.4
  • 39
    • 36849000746 scopus 로고    scopus 로고
    • 2 expression by peroxisome proliferator-activated receptors (PPARs) in rat vascular smooth muscle cells: Cooperation between PPARβ and the proto-oncogene BCL-6
    • 2 expression by peroxisome proliferator-activated receptors (PPARs) in rat vascular smooth muscle cells: cooperation between PPARβ and the proto-oncogene BCL-6. Mol Cell Biol 2007, 27:8374-8387
    • (2007) Mol Cell Biol , vol.27 , pp. 8374-8387
    • Ravaux, L.1    Denoyelle, C.2    Monne, C.3    Limon, I.4    Raymondjean, M.5    El Hadri, K.6


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