Quantitative comparison of transient growth of Saccharomyces cerevisiae, Saccharomyces kluyveri, and Kluyveromyces lactis

Biotechnology and Bioengineering

Volumn 81, Issue 7, 2003, Pages 837-847

  Herwig, Christoph ^a   Von Stockar, Urs ^a  

^a EPFL   (Switzerland)

Author keywords

K. lactis; Metabolic regulations; S. cerevisiae; S. kluyveri; Transient experiments

Indexed keywords

ETHANOL; FERMENTATION; GLUCOSE; GROWTH KINETICS; METABOLISM;

TRANSIENT GROWTH;

YEAST;

CARBON; GLUCOSE;

ARTICLE; BIOMASS; BIOSYNTHESIS; CATABOLISM; CONTROLLED STUDY; DILUTION; ENERGY; FERMENTATION; FUNGAL STRAIN; FUNGUS GROWTH; KLUYVEROMYCES; METABOLISM; NONHUMAN; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES KLUYVERI; STEADY STATE;

ADAPTATION, PHYSIOLOGICAL; COMPUTER SIMULATION; GLUCOSE; KLUYVEROMYCES; METABOLISM; MODELS, BIOLOGICAL; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SPECIES SPECIFICITY;

KLUYVEROMYCES; KLUYVEROMYCES LACTIS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES KLUYVERI;

EID: 0037473190     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10529     Document Type: Article

References (32)

1. Alexander MA, Jeffries TW. 1990. Respiratory efficiency and metabolite partitioning as regulatory phenomena in yeasts. Enz Microb Tech 12: 2-19.
2. Bisson LF, Coons DM, Kruckeberg AL, Lewis DA. 1993. Yeast sugar transporters. Crit Rev Biochem Mol Biol 28:259-308.
3. Chen XJ, Clark-Walker GD. 2000. The petite mutation in yeasts. Int Rev Cytol 194:197-238.
4. Crabtree. 1929. Observations on the carbohydrate metabolism of tumours. Biochem J 23:536-545.
5. Duboc P, Cascao-Pereira LG, von Stockar U. 1998a. Identification and control of oxidative-metabolism in Saccharomyces cerevisiae during transient growth using calorimetric measurements. Biotechnol Bioeng 57:610-619.
6. Duboc P, von Stockar U, Villadsen J. 1998b. Simple generic model for dynamic experiments with S. cerevisiae in continuous culture: decoupling between anabolism and catabolism. Biotechnol Bioeng 60: 180-189.
7. Flikweert MT, Kuyper M, van Maris AJA, Kotter P, van Dijken JP, Pronk JT. 1999. Steady-state and transient-state analysis of growth and metabolite production in a Saccharomyces cerevisiae strain with reduced pyruvate-decarboxylase activity. Biotechnol Bioeng 66:42-50.
8. Gancedo JM. 1998. Yeast carbon catabolite repression. Microbiol Mol Biol Rev 62:334-361.
9. Herwig C, Marison IW, von Stockar U. 2001. On-line stoichiometry and identification of metabolic state in dynamic process conditions. Biotechnol Bioeng 75:345-354.
10. Kiers J, Zeeman AM, Luttik M, Thiele C, Castrillo JI, Steensma HY, van Dijken JP, Pronk JT. 1998. Regulation of alcoholic fermentation in batch and chemostat cultures of Kluyveromyces lactis CBS2359. Yeast 14:459-469.
11. Kuenzi MT, Fiechter A. 1972. Regulation of carbohydrate composition of Saccharomyces cerevisiae under growth limitation. Arch Mikrobiol 84:254-265.
12. Kurtzman CP, Robnett CJ. 1998. Identification and phylogeny of ascemycetous yeasts from analysis of nuclear large subunit (26S) ribosomal DNA partial sequences. Antonie van Leeuwenhoek 73:331-371.
13. Larsson C, Von Stockar U, Marison I, Gustafsson L. 1995. Metabolic uncoupling in Saccharomyces cerevisiae. Thermochim Acta 251: 99-110.
14. Moller K. 2001. Glucose metabolism in the Petite-negative yeast Saccharomyces kluyveri. Center for Process Biotechnology, Ph.D. thesis, DTU, Denmark.
15. Moller K, Olsson L, Piskur J. 2001. Ability of anaerobic growth is not sufficient for development of the petite phenotype in Saccharomyces kluyveri. J Bacteriol 183:2485-2489.
16. Nissen TL, et al. 1997. Flux distributions in anaerobic, glucose-limited continuous cultures of Saccharomyces cerevisiae. Microbiol UK 143: 203-218
17. Pronk JT, Steensma HY, van Dijken JP. 1996. Pyruvate metabolism in Saccharomyces cerevisiae. Yeast 12:1607-1633.
18. Rieger M, Käppeli O, Fiechter A. 1983. The role of limited respiration in the incomplete oxidation of glucose by Saccharomyces cerevisiae. J Gen Microbiol 129:653-661.
19. Schmidt K, et al. 1998. C13 tracer experiments and metabolite balancing for metabolic flux analysis: comparing two approaches. Biotechnol Bioeng 58:254-257.
20. Steensma HY. 1997. From pyruvate to acetyl-coenzyme A and oxaloacetate. In: Zimmermann FK, Entian KD, editors. Yeast sugar metabolism. Lancaster, UK: Technomic Publishing. p 45-65.
21. Stephanopoulos G, Aristidou A, Nielsen J. 1998. Metabolic engineering: principles and methodologies. New York: Academic Press.
22. Tempest DW, Neijssel OM. 1992. Physiological and energetic aspects of bacterial metabolite overproduction. FEMS Microbiol Lett 100: 169-176.
23. Thevelein JM, Hohmann S. 1995. Trehalose synthase: guard to the gate of glycolysis in yeast. TIBS 20:3-10.
24. van der Heijden RTJM, Romein B, Heijnen JJ, Hellinga C, Luyben KCAM. 1994. Linear constraint relations in biochemical reaction systems. II. Diagnosis and estimation of gross errors. Biotechnol Bioeng 43:11-20.
25. van Urk H, Postma E, Scheffers WA, van Dijken JP. 1989. Glucose transport in Crabtree-positive and Crabtree-negative yeasts. J Gen Microbiol 135:2399-2406.
26. van Urk H, Voll WSL, Scheffers WA, van Dijken JP. 1990. Transient-state analysis of metabolic fluxes in Crabtree-positive and Crabtree-negative yeasts. Appl Env. Microbiol 56:281-287.
27. Verduyn C, Postma E, Scheffers W, van Dijken JP. 1990. Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J Gen Microbiol 136:395-403.
28. Verduyn C, Postma E, Scheffers W, van Dijken JP. 1992. Effect of benzoic acid on metabolic fluxes in yeasts. Yeast 8:501-517.
29. Wang NS, Stephanopoulos G. 1983. Application of macroscopic balances to the identification of gross measurement errors. Biotechnol Bioeng 25:2177-2208.
30. Wesolowski-Louvel M, Breunig KD, Fukuhara H. 2001. Kluyveromyces lactis. In: Wolf K, editor. Nonconventional yeasts in biotechnology. Berlin-Heidelberg: Springer. p 139-202.
31. Zeeman AM. 2000. Pyruvate metabolism in the yeast Kluyveromyces lactis. Ph.D. thesis.
32. Zeeman AM, Kuyper M, Pronk JT, van Dijken JP, de Steensma HY. 2000. Regulation of pyruvate metabolism in chemostat cultures of Kluyveromyces lactis CBS 2359. Yeast 16:611-620.