메뉴 건너뛰기




Volumn 128, Issue 4, 2007, Pages 858-867

Improving the batch-to-batch reproducibility of microbial cultures during recombinant protein production by regulation of the total carbon dioxide production

Author keywords

PAT; Recombinant proteins; Reproducibility

Indexed keywords

BIOMASS; CARBON DIOXIDE; ESCHERICHIA COLI; FERMENTATION; GROWTH KINETICS; PHYSIOLOGY; PROTEINS;

EID: 33847337911     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2006.12.022     Document Type: Article
Times cited : (30)

References (13)
  • 1
    • 4644266893 scopus 로고    scopus 로고
    • PAT: taking process monitoring to next level
    • DePalma A. PAT: taking process monitoring to next level. Gen. Eng. News 24 9 (2004) 46-47
    • (2004) Gen. Eng. News , vol.24 , Issue.9 , pp. 46-47
    • DePalma, A.1
  • 2
    • 33847369498 scopus 로고    scopus 로고
    • FDA, 2004. Guidance for Industry: PAT-A Framework for Innovative Pharmaceutical Manufacturing & Quality Assurance, http://www.fda.gov/cvm/guidance/published.html.
  • 3
    • 33744784043 scopus 로고    scopus 로고
    • Application of model predictive control to cultivation processes for protein production with genetically modified bacteria
    • Pons M.N., and van Impe J.F.M. (Eds), IFAC/Elsevier ISBN 0 08 044251 X
    • Jenzsch M., Simutis R., and Lübbert A. Application of model predictive control to cultivation processes for protein production with genetically modified bacteria. In: Pons M.N., and van Impe J.F.M. (Eds). Computer Application in Biotechnology 2004 (CAB9) (2005), IFAC/Elsevier 511-516 ISBN 0 08 044251 X
    • (2005) Computer Application in Biotechnology 2004 (CAB9) , pp. 511-516
    • Jenzsch, M.1    Simutis, R.2    Lübbert, A.3
  • 4
    • 33645360262 scopus 로고    scopus 로고
    • Generic model control of the specific growth rate in recombinant Escherichia coli cultivations
    • Jenzsch M., Simutis R., and Lübbert A. Generic model control of the specific growth rate in recombinant Escherichia coli cultivations. J. Biotechnol. 122 4 (2006) 483-493
    • (2006) J. Biotechnol. , vol.122 , Issue.4 , pp. 483-493
    • Jenzsch, M.1    Simutis, R.2    Lübbert, A.3
  • 5
    • 33751269309 scopus 로고    scopus 로고
    • Improving the batch-to-batch reproducibility in microbial cultures during recombinant protein production by guiding the process along a predefined total biomass profile
    • Jenzsch M., Gnoth S., Kleinschmidt M., Simutis R., and Lübbert A. Improving the batch-to-batch reproducibility in microbial cultures during recombinant protein production by guiding the process along a predefined total biomass profile. Bioproc. Biosyst. Eng. 29 (2006) 315-321
    • (2006) Bioproc. Biosyst. Eng. , vol.29 , pp. 315-321
    • Jenzsch, M.1    Gnoth, S.2    Kleinschmidt, M.3    Simutis, R.4    Lübbert, A.5
  • 6
    • 33751290076 scopus 로고    scopus 로고
    • Open loop control of the biomass concentration within the growth phase of recombinant protein production processes
    • Jenzsch M., Gnoth S., Beck M., Kleinschmidt M., Simutis R., and Lübbert A. Open loop control of the biomass concentration within the growth phase of recombinant protein production processes. J. Biotechnol. 127 (2006) 84-94
    • (2006) J. Biotechnol. , vol.127 , pp. 84-94
    • Jenzsch, M.1    Gnoth, S.2    Beck, M.3    Kleinschmidt, M.4    Simutis, R.5    Lübbert, A.6
  • 7
    • 33645736967 scopus 로고    scopus 로고
    • Estimation of biomass concentrations in fermentation processes for recombinant protein production
    • Jenzsch M., Simutis R., Eisbrenner G., Stückrath I., and Lübbert A. Estimation of biomass concentrations in fermentation processes for recombinant protein production. Bioproc. Biosyst. Eng. 29 1 (2006) 19-27
    • (2006) Bioproc. Biosyst. Eng. , vol.29 , Issue.1 , pp. 19-27
    • Jenzsch, M.1    Simutis, R.2    Eisbrenner, G.3    Stückrath, I.4    Lübbert, A.5
  • 8
    • 85047678619 scopus 로고    scopus 로고
    • Automatic control of the specific growth rate in fed-batch cultivations processes based on exhaust gas analysis
    • Levisauskas D., Simutis R., Borvitz D., and Lübbert A. Automatic control of the specific growth rate in fed-batch cultivations processes based on exhaust gas analysis. Bioproc. Eng. (1996) 145-150
    • (1996) Bioproc. Eng. , pp. 145-150
    • Levisauskas, D.1    Simutis, R.2    Borvitz, D.3    Lübbert, A.4
  • 9
    • 0001010013 scopus 로고
    • A kinetic study of the lactic acid fermentation. Batch process at controlled pH
    • Luedeking R., and Piret E.L. A kinetic study of the lactic acid fermentation. Batch process at controlled pH. J. Biochem. Microbiol. Technol. Eng. 1 (1959) 393-412
    • (1959) J. Biochem. Microbiol. Technol. Eng. , vol.1 , pp. 393-412
    • Luedeking, R.1    Piret, E.L.2
  • 10
    • 0000488907 scopus 로고
    • Transient and steady state continuous fermentation. Theory and experiment
    • Luedeking R., and Piret E.L. Transient and steady state continuous fermentation. Theory and experiment. J. Biochem. Microbiol. Technol. Eng. 1 (1959) 431-459
    • (1959) J. Biochem. Microbiol. Technol. Eng. , vol.1 , pp. 431-459
    • Luedeking, R.1    Piret, E.L.2
  • 13
    • 0001769993 scopus 로고
    • Optimization and control in fed-batch bioreactors
    • Shioya S. Optimization and control in fed-batch bioreactors. Adv. Biochem. Eng. Biotechnol. 46 (1992) 111-142
    • (1992) Adv. Biochem. Eng. Biotechnol. , vol.46 , pp. 111-142
    • Shioya, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.