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Volumn 130, Issue 1, 2007, Pages 39-46

Sorbitol co-feeding reduces metabolic burden caused by the overexpression of a Rhizopus oryzae lipase in Pichia pastoris

Author keywords

Fed batch cultivation; Metabolic burden; Mixed substrate co feeding; Pichia pastoris; Rhizopus oryzae lipase; Sorbitol

Indexed keywords

ASSIMILATION CAPACITY; PHENOTYPES; PICHIA PASTORIS; RHIZOPUS ORYZAE LIPASES; SORBITOLS;

EID: 34247347868     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2007.02.025     Document Type: Article
Times cited : (79)

References (28)
  • 1
    • 0025168284 scopus 로고
    • Fermentation development of recombinant Pichia pastoris expressing the heterologous gene: bovine lysozyme
    • Brierley R.A., Bussineau C., Kosson R., Melton A., and Siegel R.S. Fermentation development of recombinant Pichia pastoris expressing the heterologous gene: bovine lysozyme. Ann. NY Acad. Sci. 589 (1990) 350-362
    • (1990) Ann. NY Acad. Sci. , vol.589 , pp. 350-362
    • Brierley, R.A.1    Bussineau, C.2    Kosson, R.3    Melton, A.4    Siegel, R.S.5
  • 2
    • 25144440587 scopus 로고    scopus 로고
    • Heterologous protein production of Rhizopus oryzae lipasa in Pichia pastoris using the alcohol oxidase and formaldehyde dehydrogenase promoters in batch and fed-batch cultures
    • Cos O., Resina D., Ferrer P., Montesinos J.L., and Valero F. Heterologous protein production of Rhizopus oryzae lipasa in Pichia pastoris using the alcohol oxidase and formaldehyde dehydrogenase promoters in batch and fed-batch cultures. Biochem. Eng. J. 26 (2005) 86-94
    • (2005) Biochem. Eng. J. , vol.26 , pp. 86-94
    • Cos, O.1    Resina, D.2    Ferrer, P.3    Montesinos, J.L.4    Valero, F.5
  • 3
    • 20044389443 scopus 로고    scopus 로고
    • Combined effect of the methanol utilization (Mut) phenotype and gene dosage on recombinant protein production in Pichia pastoris fed-batch cultures
    • Cos O., Serrano A., Montesinos J.L., Ferrer P., Cregg J.M., and Valero F. Combined effect of the methanol utilization (Mut) phenotype and gene dosage on recombinant protein production in Pichia pastoris fed-batch cultures. J. Biotechnol. 116 (2005) 321-335
    • (2005) J. Biotechnol. , vol.116 , pp. 321-335
    • Cos, O.1    Serrano, A.2    Montesinos, J.L.3    Ferrer, P.4    Cregg, J.M.5    Valero, F.6
  • 4
    • 33748425718 scopus 로고    scopus 로고
    • A simple model-based control for Pichia pastoris allows a more efficient heterologous protein production bioprocess
    • Cos O., Ramon R., Montesinos J.L., and Valero F. A simple model-based control for Pichia pastoris allows a more efficient heterologous protein production bioprocess. Biotechnol. Bioeng. 95 (2006) 145-154
    • (2006) Biotechnol. Bioeng. , vol.95 , pp. 145-154
    • Cos, O.1    Ramon, R.2    Montesinos, J.L.3    Valero, F.4
  • 5
    • 33748915125 scopus 로고    scopus 로고
    • Operational strategies, monitoring and control of heterologous protein production in the methylotrophic yeast Pichia pastoris under different promoters: a review
    • Cos O., Ramon R., Montesinos J.L., and Valero F. Operational strategies, monitoring and control of heterologous protein production in the methylotrophic yeast Pichia pastoris under different promoters: a review. Microbial Cell Factories 5 (2006) 17
    • (2006) Microbial Cell Factories , vol.5 , pp. 17
    • Cos, O.1    Ramon, R.2    Montesinos, J.L.3    Valero, F.4
  • 7
    • 33748414105 scopus 로고    scopus 로고
    • Recombinant protein production with Pichia pastoris in continuous fermentation-kinetic analysis of growth and product formation
    • Curvers S., Linnemann J., Klauser T., Wandrey C., and Takors R. Recombinant protein production with Pichia pastoris in continuous fermentation-kinetic analysis of growth and product formation. Eng. Life Sci. 28 (2002) 229-235
    • (2002) Eng. Life Sci. , vol.28 , pp. 229-235
    • Curvers, S.1    Linnemann, J.2    Klauser, T.3    Wandrey, C.4    Takors, R.5
  • 8
    • 0035807422 scopus 로고    scopus 로고
    • A Pichia pastoris fermentation process for producing high-levels of recombinant human cystatin-C
    • Files D., Ogawa M., Scaman C.H., and Baldwin S.A. A Pichia pastoris fermentation process for producing high-levels of recombinant human cystatin-C. Enzyme Microb. Technol. 29 (2001) 335-340
    • (2001) Enzyme Microb. Technol. , vol.29 , pp. 335-340
    • Files, D.1    Ogawa, M.2    Scaman, C.H.3    Baldwin, S.A.4
  • 10
    • 0035703883 scopus 로고    scopus 로고
    • Non-repressing carbon sources for alcohol oxidase (AOX1) promoter of Pichia pastoris
    • Inan M., and Meagher M.M. Non-repressing carbon sources for alcohol oxidase (AOX1) promoter of Pichia pastoris. J. Biosci. Bioeng. 92 (2001) 585-589
    • (2001) J. Biosci. Bioeng. , vol.92 , pp. 585-589
    • Inan, M.1    Meagher, M.M.2
  • 11
    • 0032416188 scopus 로고    scopus 로고
    • Effect of methanol concentration on the production of human beta(2)-glycoprotein I domain V by a recombinant Pichia pastoris: a simple system for the control of methanol concentration using a semiconductor gas sensor
    • Katakura Y., Zhang W.H., Zhuang G.Q., Omasa T., Kishimoto M., Goto W., and Suga K.I. Effect of methanol concentration on the production of human beta(2)-glycoprotein I domain V by a recombinant Pichia pastoris: a simple system for the control of methanol concentration using a semiconductor gas sensor. J. Ferm. Bioeng. 86 (1998) 482-487
    • (1998) J. Ferm. Bioeng. , vol.86 , pp. 482-487
    • Katakura, Y.1    Zhang, W.H.2    Zhuang, G.Q.3    Omasa, T.4    Kishimoto, M.5    Goto, W.6    Suga, K.I.7
  • 12
    • 0033955337 scopus 로고    scopus 로고
    • Heterologous protein expression in the methylotrophic yeast Pichia pastoris
    • Lin Cereghino J., and Cregg J.M. Heterologous protein expression in the methylotrophic yeast Pichia pastoris. FEMS Microbiol. Rev. 24 (2000) 45-66
    • (2000) FEMS Microbiol. Rev. , vol.24 , pp. 45-66
    • Lin Cereghino, J.1    Cregg, J.M.2
  • 13
    • 0030659014 scopus 로고    scopus 로고
    • Biosynthetic production of type II fish antifreezen protein fermentation by Pichia pastoris
    • Loewen M.C., Liu X., Davies P.L., and Daugulis A.J. Biosynthetic production of type II fish antifreezen protein fermentation by Pichia pastoris. Appl. Microbiol. Biotechnol. 48 (1997) 480-486
    • (1997) Appl. Microbiol. Biotechnol. , vol.48 , pp. 480-486
    • Loewen, M.C.1    Liu, X.2    Davies, P.L.3    Daugulis, A.J.4
  • 14
    • 17244363998 scopus 로고    scopus 로고
    • Heterologous protein production using the Pichia pastoris expression system
    • Macauley-Patrick S., Fazenda M.L., McNeil B., and Harvey L.M. Heterologous protein production using the Pichia pastoris expression system. Yeast 22 (2005) 249-270
    • (2005) Yeast , vol.22 , pp. 249-270
    • Macauley-Patrick, S.1    Fazenda, M.L.2    McNeil, B.3    Harvey, L.M.4
  • 16
    • 0035831305 scopus 로고    scopus 로고
    • Optimization of the high-level production of Rhizopus oryzae lipase in Pichia pastoris
    • Minning S., Serrano A., Ferrer P., Sola C., Schmid R.D., and Valero F. Optimization of the high-level production of Rhizopus oryzae lipase in Pichia pastoris. J. Biotechnol. 86 (2001) 59-70
    • (2001) J. Biotechnol. , vol.86 , pp. 59-70
    • Minning, S.1    Serrano, A.2    Ferrer, P.3    Sola, C.4    Schmid, R.D.5    Valero, F.6
  • 17
    • 21644447149 scopus 로고    scopus 로고
    • Improving the monitoring of methanol concentration during high cell density fermentation of Pichia pastoris
    • Ramon R., Feliu J.X., Cos O., Montesinos J.L., Berthet F.X., and Valero F. Improving the monitoring of methanol concentration during high cell density fermentation of Pichia pastoris. Biotechnol. Lett. 26 (2004) 1447-1452
    • (2004) Biotechnol. Lett. , vol.26 , pp. 1447-1452
    • Ramon, R.1    Feliu, J.X.2    Cos, O.3    Montesinos, J.L.4    Berthet, F.X.5    Valero, F.6
  • 18
    • 1842530437 scopus 로고    scopus 로고
    • Expression of a Rhizopus oryzae lipase in Pichia pastoris under control of the nitrogen source-regulated formaldehyde dehydrogenase promoter
    • Resina D., Serrano A., Valero F., and Ferrer P. Expression of a Rhizopus oryzae lipase in Pichia pastoris under control of the nitrogen source-regulated formaldehyde dehydrogenase promoter. J. Biotechnol. 109 (2004) 103-113
    • (2004) J. Biotechnol. , vol.109 , pp. 103-113
    • Resina, D.1    Serrano, A.2    Valero, F.3    Ferrer, P.4
  • 19
    • 24644465009 scopus 로고    scopus 로고
    • Developing high cell density fed-batch cultivation strategies for heterologous protein production in Pichia pastoris using the nitrogen source-regulated FLD1 promoter
    • Resina D., Cos O., Ferrer P., and Valero F. Developing high cell density fed-batch cultivation strategies for heterologous protein production in Pichia pastoris using the nitrogen source-regulated FLD1 promoter. Biotechnol. Bioeng. 91 (2005) 760-767
    • (2005) Biotechnol. Bioeng. , vol.91 , pp. 760-767
    • Resina, D.1    Cos, O.2    Ferrer, P.3    Valero, F.4
  • 21
    • 0031608474 scopus 로고    scopus 로고
    • High cell-density fermentation
    • Higgins D.R., and Cregg J.M. (Eds), Humana Press, Totowa, NJ
    • Stratton J., Chiruvolu V., and Meagher M.M. High cell-density fermentation. In: Higgins D.R., and Cregg J.M. (Eds). Methods in Molecular Biology vol. 103 (1998), Humana Press, Totowa, NJ 107-120
    • (1998) Methods in Molecular Biology , vol.103 , pp. 107-120
    • Stratton, J.1    Chiruvolu, V.2    Meagher, M.M.3
  • 22
    • 0032854877 scopus 로고    scopus 로고
    • Sorbitol as a non-repressing carbon source for fed-batch fermentation of recombinant Pichia pastoris
    • Thorpe E.D., d'Anjou M.C., and Daugulis A.J. Sorbitol as a non-repressing carbon source for fed-batch fermentation of recombinant Pichia pastoris. Biotechnol. Lett. 21 (1999) 669-672
    • (1999) Biotechnol. Lett. , vol.21 , pp. 669-672
    • Thorpe, E.D.1    d'Anjou, M.C.2    Daugulis, A.J.3
  • 23
    • 11144283607 scopus 로고    scopus 로고
    • Use of different carbon sources in cultivation of recombinant Pichia pastoris for angiostatin production
    • Xie J.L., Zhou Q.W., Pen D., Gan R.B., and Qin Y. Use of different carbon sources in cultivation of recombinant Pichia pastoris for angiostatin production. Enzyme Microb. Technol. 36 (2005) 210-216
    • (2005) Enzyme Microb. Technol. , vol.36 , pp. 210-216
    • Xie, J.L.1    Zhou, Q.W.2    Pen, D.3    Gan, R.B.4    Qin, Y.5
  • 24
    • 0000193228 scopus 로고    scopus 로고
    • Fermentation strategies for recombinant protein expression in the methylotrophic yeast Pichia pastoris
    • Zhang W., Inan M., and Meagher M.M. Fermentation strategies for recombinant protein expression in the methylotrophic yeast Pichia pastoris. Biotechnol. Bioproc. Eng. 5 (2000) 275-287
    • (2000) Biotechnol. Bioproc. Eng. , vol.5 , pp. 275-287
    • Zhang, W.1    Inan, M.2    Meagher, M.M.3
  • 25
    • 0034610097 scopus 로고    scopus 로고
    • Modeling Pichia pastoris growth on methanol and optimizing the production of a recombinant protein, the heavy-chain fragment C of botulinum neurotoxin, serotype A
    • Zhang W.H., Bevins M.A., Plantz B.A., Smith L.A., and Meagher M.M. Modeling Pichia pastoris growth on methanol and optimizing the production of a recombinant protein, the heavy-chain fragment C of botulinum neurotoxin, serotype A. Biotechnol. Bioeng. 70 (2000) 1-8
    • (2000) Biotechnol. Bioeng. , vol.70 , pp. 1-8
    • Zhang, W.H.1    Bevins, M.A.2    Plantz, B.A.3    Smith, L.A.4    Meagher, M.M.5
  • 27
    • 16344365158 scopus 로고    scopus 로고
    • Maximization of production of secreted recombinant proteins in Pichia pastoris fed-batch fermentation
    • Zhang W.H., Sinha J., Smith L.A., Inan M., and Meagher M.M. Maximization of production of secreted recombinant proteins in Pichia pastoris fed-batch fermentation. Biotechnol. Prog. 21 (2005) 386-393
    • (2005) Biotechnol. Prog. , vol.21 , pp. 386-393
    • Zhang, W.H.1    Sinha, J.2    Smith, L.A.3    Inan, M.4    Meagher, M.M.5
  • 28
    • 0036734202 scopus 로고    scopus 로고
    • Decrease of proteolytic degradation of recombinant hirudin produced by Pichia pastoris by controlling the specific growth rate
    • Zhou X.-S., and Zhang Y.-X. Decrease of proteolytic degradation of recombinant hirudin produced by Pichia pastoris by controlling the specific growth rate. Biotechnol. Lett. 24 (2002) 1449-1453
    • (2002) Biotechnol. Lett. , vol.24 , pp. 1449-1453
    • Zhou, X.-S.1    Zhang, Y.-X.2


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