Chrysotoxine, a novel bibenzyl compound, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-κB modulation

Neurochemistry International

Volumn 57, Issue 6, 2010, Pages 676-689

  Song, Ju Xian ^a   Shaw, Pang Chui ^b   Sze, Cho Wing ^a   Tong, Yao ^a   Yao, Xin Sheng ^c   Ng, Tzi Bun ^b   Zhang, Yan Bo ^a  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c JINAN UNIVERSITY   (China)

Author keywords

Apoptosis; Chrysotoxine; Mitochondrial dysfunctions; NF B; Parkinson's disease; Reactive oxygen species

Indexed keywords

BIBENZYL DERIVATIVE; CALCIUM ION; CASPASE 3; CHRYSOTOBIBENZYL; CHRYSOTOXINE; CREPIDATIN; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MOSCATILIN; NITRIC OXIDE; NOBILIN B; OXIDOPAMINE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL PROTECTION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NERVE DEGENERATION; NEUROBLASTOMA CELL; NEUROPROTECTION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN SECRETION; TUMOR CELL LINE; UPREGULATION;

EID: 77957021343     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2010.08.007     Document Type: Article

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