An ultrasound-responsive nano delivery system of tissue-type plasminogen activator for thrombolytic therapy

Journal of Controlled Release

Volumn 147, Issue 2, 2010, Pages 269-277

  Uesugi, Yoshiko ^a   Kawata, Hiroyuki ^b   Jo, Jun Ichiro ^a   Saito, Yoshihiko ^b   Tabata, Yasuhiko ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Gelatin; Polyethylene glycol; T PA; Thrombolytic therapy; Ultrasound

Indexed keywords

BIOLOGICAL ACTIVITIES; BLOOD CIRCULATION; BODY DISTRIBUTIONS; CATIONIZED; DELIVERY SYSTEMS; ETHYLENE DIAMINE; GELATIN; IN-VITRO; INTRAVENOUS ADMINISTRATION; NANO-DELIVERY SYSTEMS; NANO-SIZED; POLYETHYLENE GLYCOLS (PEG); RECANALIZATION; T-PA; THROMBOLYTIC; TISSUE-TYPE PLASMINOGEN ACTIVATOR; ULTRASOUND; ULTRASOUND IRRADIATION;

CARDIOVASCULAR SYSTEM; CELL CULTURE; DRUG THERAPY; DYES; IRRADIATION; POLYETHYLENE OXIDES; POLYETHYLENES; THERMOPLASTICS; ULTRASONIC TRANSMISSION; ULTRASONICS;

POLYETHYLENE GLYCOLS;

ETHYLENEDIAMINE; GELATIN; MACROGOL; MONTEPLASE; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CIRCULATION; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; EXPERIMENTAL MODEL; FEMALE; FIBRINOLYTIC THERAPY; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RECANALIZATION; THROMBOSIS; ULTRASOUND;

ANIMALS; CELL LINE; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DRUG CARRIERS; ETHYLENEDIAMINES; FIBRINOLYTIC AGENTS; FIBROBLASTS; GELATIN; MICE; NANOPARTICLES; POLYETHYLENE GLYCOLS; RABBITS; SURFACE PROPERTIES; THROMBOSIS; TISSUE DISTRIBUTION; TISSUE PLASMINOGEN ACTIVATOR; ULTRASONIC THERAPY;

EID: 77957020900     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.07.127     Document Type: Article

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