Identification and characterization of Harobin, a novel fibrino(geno)lytic serine protease from a sea snake (Lapemis hardwickii)

FEBS Letters

Volumn 581, Issue 16, 2007, Pages 2965-2973

  He, Junyun ^a   Chen, Shiyong ^a   Gu, Jun ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Antithrombosis; Defibrase; Fibrinogen; Hypertension; Sea snake; Serine protease

Indexed keywords

ANGIOTENSIN I; BATROXOBIN; BRADYKININ; CYSTEINE; FIBRINOGEN; HAROBIN; HEPARIN; KININOGEN; SERINE PROTEINASE; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOVENOUS SHUNT; ARTICLE; BACTERIOPHAGE; BLEEDING TIME; BLOOD CLOTTING TIME; BLOOD PRESSURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; ENZYME ACTIVITY; ENZYME STABILITY; FIBRINOGEN BLOOD LEVEL; FIBRINOLYSIS; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; RAT; THROMBOSIS; THROMBUS;

AMINO ACID SEQUENCE; ANGIOTENSIN I; ANIMALS; BASE SEQUENCE; BATROXOBIN; CLONING, MOLECULAR; FIBRINOLYTIC AGENTS; HYDROPHID VENOMS; HYDROPHIDAE; KININOGENS; MALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; TEMPERATURE;

HYDROPHIIDAE; LAPEMIS HARDWICKII; LONCHOCARPUS GLAUCIFOLIUS; MUS; PICHIA PASTORIS; RATTUS;

EID: 34250184500     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.05.047     Document Type: Article

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