Controlled release of hepatocyte growth factor from gelatin hydrogels based on hydrogel degradation

Journal of Drug Targeting

Volumn 9, Issue 6, 2001, Pages 461-471

  Ozeki, Makoto ^a   Ishi, Toshihiro ^a   Hirano, Yoshiaki ^a   Tabata, Yasuhiko ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Angiogenic effect; Controlled release; Gelatin hydrogel; HGF; Hydrogel degradation

Indexed keywords

GELATIN; GLUTARALDEHYDE; IODINE 125; SCATTER FACTOR; WATER;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; BIODEGRADABILITY; CAPILLARY; CHEMICAL INTERACTION; CONCENTRATION RESPONSE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CROSS LINKING; DOSE RESPONSE; DRUG ACTIVITY; DRUG DEGRADATION; DRUG EFFECT; DRUG RELEASE; HYDROGEL; IN VITRO STUDY; ISOTOPE LABELING; LEUKEMIA CELL LINE; MINK; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; RADIOIODINATION; SOLUBILITY; SUBCUTANEOUS TISSUE; TIME;

EID: 0035692862     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611860108998780     Document Type: Article

References (23)

1. "Identification and partial characterization of two classes of receptors for human hepatocyte growth factor on adult rat hepatocytes in primary culture"
2. 125I-containing acylating agent"
3. "Implantable biohybrid artificial organs"
4. "Calcium alginate beads as a slow-release system for delivering angiogenic molecules in vivo and in vitro"
5. "Controlled release of TGF-beta 1 from a biodegradable matrix for bone regeneration"
6. "Protein release from gelatin matrices"
7. "Interaction of hepatocyte growth factor with heparan sulfate"
8. "Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats"
9. "Evaluation of polylactic acid homopolymers as carriers for bone morphogenetic protein"
10. "Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor"
11. "Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor"
12. "Molecular cloning and expression of human hepatocyte growth factor"
13. "Hepatocyte growth factor/scatter factor has distinct classes of binding site in heparan sulfate from mammary cells"
14. "A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor"
15. "Heparin binding and oligomerization of hepatocyte growth factor/scatter factor isoforms. Heparan sulfate glycosaminoglycan requirement for Met binding and signaling"
16. "Vascularization effect of basic fibroblast growth factor released from gelatin hydrogels with different biodegradabilities"
17. "Bone regeneration by basic fibroblast growth factor complexed with biodegradable hydrogels"
18. "Biodegradation of hydrogel carrier incorporating fibroblast growth factor"
19. "Growth factors in the extracellular matrix"
20. "Reguration of cell growth and motility by hepatocyte growth factor and receptor expression in various cell species"
21. "Evidence for the identity of human scatter factor and human hepatocyte growth factor"
22. "Hepatocyte growth factor increase expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells"