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Volumn 40, Issue 2, 2010, Pages 164-175

The Involvement of Heat-Shock Proteins in the Pathogenesis of Autoimmune Arthritis: A Critical Appraisal

Author keywords

Animal models; Heat shock proteins; Immune response; Pathogenesis; Rheumatoid arthritis

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 10; HEAT SHOCK PROTEIN 22; HEAT SHOCK PROTEIN 32; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 47; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 65; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; HLA DR4 ANTIGEN; SNX 4414; SNX 7081; UNCLASSIFIED DRUG;

EID: 77957018293     PISSN: 00490172     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2009.10.002     Document Type: Review
Times cited : (30)

References (149)
  • 1
    • 19444364080 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • McGraw-Hill, New York (NY), D. Kasper, E. Braunwald, A. Fauci, S. Hauser, D. Longo, J. Jameson (Eds.)
    • Lipsky P.E. Rheumatoid arthritis. Harrison's Principles of Internal Medicine 2005, 1968-1977. McGraw-Hill, New York (NY). 16th edition. D. Kasper, E. Braunwald, A. Fauci, S. Hauser, D. Longo, J. Jameson (Eds.).
    • (2005) Harrison's Principles of Internal Medicine , pp. 1968-1977
    • Lipsky, P.E.1
  • 2
    • 0031968825 scopus 로고    scopus 로고
    • Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States
    • Lawrence R.C., Helmick C.G., Arnett F.C., Deyo R.A., Felson D.T., Giannini E.H., et al. Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum 1998, 41(5):778-799.
    • (1998) Arthritis Rheum , vol.41 , Issue.5 , pp. 778-799
    • Lawrence, R.C.1    Helmick, C.G.2    Arnett, F.C.3    Deyo, R.A.4    Felson, D.T.5    Giannini, E.H.6
  • 3
    • 0025304539 scopus 로고
    • Rheumatoid arthritis. Pathophysiology and implications for therapy
    • Harris E.D. Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med 1990, 322(18):1277-1289.
    • (1990) N Engl J Med , vol.322 , Issue.18 , pp. 1277-1289
    • Harris, E.D.1
  • 6
    • 0036512171 scopus 로고    scopus 로고
    • Roles of heat-shock proteins in innate and adaptive immunity
    • Srivastava P. Roles of heat-shock proteins in innate and adaptive immunity. Nat Rev Immunol 2002, 2(3):185-194.
    • (2002) Nat Rev Immunol , vol.2 , Issue.3 , pp. 185-194
    • Srivastava, P.1
  • 8
    • 0020684764 scopus 로고
    • Lines of T lymphocytes induce or vaccinate against autoimmune arthritis
    • Holoshitz J., Naparstek Y., Ben-Nun A., Cohen I.R. Lines of T lymphocytes induce or vaccinate against autoimmune arthritis. Science 1983, 219(4580):56-58.
    • (1983) Science , vol.219 , Issue.4580 , pp. 56-58
    • Holoshitz, J.1    Naparstek, Y.2    Ben-Nun, A.3    Cohen, I.R.4
  • 9
    • 0024285835 scopus 로고
    • Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis
    • van Eden W., Thole J.E., van der Zee R., Noordzij A., van Embden J.D., Hensen E.J., et al. Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis. Nature 1988, 331(6152):171-173.
    • (1988) Nature , vol.331 , Issue.6152 , pp. 171-173
    • van Eden, W.1    Thole, J.E.2    van der Zee, R.3    Noordzij, A.4    van Embden, J.D.5    Hensen, E.J.6
  • 10
    • 0037105543 scopus 로고    scopus 로고
    • Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60
    • Quintana F.J., Carmi P., Mor F., Cohen I.R. Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60. J Immunol 2002, 169(6):3422-3428.
    • (2002) J Immunol , vol.169 , Issue.6 , pp. 3422-3428
    • Quintana, F.J.1    Carmi, P.2    Mor, F.3    Cohen, I.R.4
  • 11
    • 0030956660 scopus 로고    scopus 로고
    • Diversification of T cell responses to carboxy-terminal determinants within the 65-kD heat-shock protein is involved in regulation of autoimmune arthritis
    • Moudgil K.D., Chang T.T., Eradat H., Chen A.M., Gupta R.S., Brahn E., et al. Diversification of T cell responses to carboxy-terminal determinants within the 65-kD heat-shock protein is involved in regulation of autoimmune arthritis. J Exp Med 1997, 185(7):1307-1316.
    • (1997) J Exp Med , vol.185 , Issue.7 , pp. 1307-1316
    • Moudgil, K.D.1    Chang, T.T.2    Eradat, H.3    Chen, A.M.4    Gupta, R.S.5    Brahn, E.6
  • 12
    • 0037097641 scopus 로고    scopus 로고
    • Resistance to adjuvant arthritis is due to protective antibodies against heat shock protein surface epitopes and the induction of IL-10 secretion
    • Ulmansky R., Cohen C.J., Szafer F., Moallem E., Fridlender Z.G., Kashi Y., et al. Resistance to adjuvant arthritis is due to protective antibodies against heat shock protein surface epitopes and the induction of IL-10 secretion. J Immunol 2002, 168(12):6463-6469.
    • (2002) J Immunol , vol.168 , Issue.12 , pp. 6463-6469
    • Ulmansky, R.1    Cohen, C.J.2    Szafer, F.3    Moallem, E.4    Fridlender, Z.G.5    Kashi, Y.6
  • 14
    • 0024378213 scopus 로고
    • Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein
    • van den Broek M.F., Hogervorst E.J., Van Bruggen M.C., Van Eden W., van der Zee R., van den Berg W.B. Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein. J Exp Med 1989, 170(2):449-466.
    • (1989) J Exp Med , vol.170 , Issue.2 , pp. 449-466
    • van den Broek, M.F.1    Hogervorst, E.J.2    Van Bruggen, M.C.3    Van Eden, W.4    van der Zee, R.5    van den Berg, W.B.6
  • 15
    • 21244492732 scopus 로고    scopus 로고
    • Heat shock protein 65-reactive T cells are involved in the pathogenesis of non-antigenic dimethyl dioctadecyl ammonium bromide-induced arthritis
    • Mia M.Y., Durai M., Kim H.R., Moudgil K.D. Heat shock protein 65-reactive T cells are involved in the pathogenesis of non-antigenic dimethyl dioctadecyl ammonium bromide-induced arthritis. J Immunol 2005, 175(1):219-227.
    • (2005) J Immunol , vol.175 , Issue.1 , pp. 219-227
    • Mia, M.Y.1    Durai, M.2    Kim, H.R.3    Moudgil, K.D.4
  • 16
    • 0034010390 scopus 로고    scopus 로고
    • The route of administration of an immunodominant peptide derived from heat-shock protein 65 dramatically affects disease outcome in pristane-induced arthritis
    • Francis J.N., Lamont A.G., Thompson S.J. The route of administration of an immunodominant peptide derived from heat-shock protein 65 dramatically affects disease outcome in pristane-induced arthritis. Immunology 2000, 99(3):338-344.
    • (2000) Immunology , vol.99 , Issue.3 , pp. 338-344
    • Francis, J.N.1    Lamont, A.G.2    Thompson, S.J.3
  • 17
    • 49949152455 scopus 로고    scopus 로고
    • Expression of heat shock protein receptors on fibroblast-like synovial cells derived from rheumatoid arthritis-affected joints
    • Hromadnikova I., Nguyen T.T., Zlacka D., Sedlackova L., Popelka S., Veigl D., et al. Expression of heat shock protein receptors on fibroblast-like synovial cells derived from rheumatoid arthritis-affected joints. Rheumatol Int 2008, 28(9):837-844.
    • (2008) Rheumatol Int , vol.28 , Issue.9 , pp. 837-844
    • Hromadnikova, I.1    Nguyen, T.T.2    Zlacka, D.3    Sedlackova, L.4    Popelka, S.5    Veigl, D.6
  • 18
    • 57349131655 scopus 로고    scopus 로고
    • Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis
    • Rice J.W., Veal J.M., Fadden R.P., Barabasz A.F., Partridge J.M., Barta T.E., et al. Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis. Arthritis Rheum 2008, 58(12):3765-3775.
    • (2008) Arthritis Rheum , vol.58 , Issue.12 , pp. 3765-3775
    • Rice, J.W.1    Veal, J.M.2    Fadden, R.P.3    Barabasz, A.F.4    Partridge, J.M.5    Barta, T.E.6
  • 19
    • 0031051988 scopus 로고    scopus 로고
    • Characteristics of synovial fluid effusion in collagen-induced arthritis (CIA) in the DA rat; a comparison of histology and antibody reactivities in an experimental chronic arthritis model and rheumatoid arthritis (RA)
    • Erlandsson Harris H., Liljestrom M., Klareskog L. Characteristics of synovial fluid effusion in collagen-induced arthritis (CIA) in the DA rat; a comparison of histology and antibody reactivities in an experimental chronic arthritis model and rheumatoid arthritis (RA). Clin Exp Immunol 1997, 107(3):480-484.
    • (1997) Clin Exp Immunol , vol.107 , Issue.3 , pp. 480-484
    • Erlandsson Harris, H.1    Liljestrom, M.2    Klareskog, L.3
  • 21
    • 33749679152 scopus 로고    scopus 로고
    • Frequency of anti-hsp60, -65 and -70 antibodies in sera of patients with juvenile idiopathic arthritis
    • Zlacka D., Vavrincova P., Hien Nguyen T.T., Hromadnikova I. Frequency of anti-hsp60, -65 and -70 antibodies in sera of patients with juvenile idiopathic arthritis. J Autoimmun 2006, 27(2):81-88.
    • (2006) J Autoimmun , vol.27 , Issue.2 , pp. 81-88
    • Zlacka, D.1    Vavrincova, P.2    Hien Nguyen, T.T.3    Hromadnikova, I.4
  • 22
    • 33750808902 scopus 로고    scopus 로고
    • Antibody responses to mycobacterial and self heat shock protein 65 in autoimmune arthritis: epitope specificity and implication in pathogenesis
    • Kim H.R., Kim E.Y., Cerny J., Moudgil K.D. Antibody responses to mycobacterial and self heat shock protein 65 in autoimmune arthritis: epitope specificity and implication in pathogenesis. J Immunol 2006, 177(10):6634-6641.
    • (2006) J Immunol , vol.177 , Issue.10 , pp. 6634-6641
    • Kim, H.R.1    Kim, E.Y.2    Cerny, J.3    Moudgil, K.D.4
  • 24
    • 0027175881 scopus 로고
    • Heat shock (stress) proteins and autoimmunity in rheumatic diseases
    • Schultz D.R., Arnold P.I. Heat shock (stress) proteins and autoimmunity in rheumatic diseases. Semin Arthritis Rheum 1993, 22(6):357-374.
    • (1993) Semin Arthritis Rheum , vol.22 , Issue.6 , pp. 357-374
    • Schultz, D.R.1    Arnold, P.I.2
  • 25
    • 84961016706 scopus 로고
    • Development of arthritis, periarthritis and periostitis in rats given adjuvants
    • Pearson C.M. Development of arthritis, periarthritis and periostitis in rats given adjuvants. Proc Soc Exp Biol Med 1956, 91(1):95-101.
    • (1956) Proc Soc Exp Biol Med , vol.91 , Issue.1 , pp. 95-101
    • Pearson, C.M.1
  • 26
    • 0023885154 scopus 로고
    • Streptococcal cell-wall-induced arthritis in rats: an overview
    • Wilder R.L. Streptococcal cell-wall-induced arthritis in rats: an overview. Int J Tissue React 1988, 10(1):1-5.
    • (1988) Int J Tissue React , vol.10 , Issue.1 , pp. 1-5
    • Wilder, R.L.1
  • 27
    • 0033711727 scopus 로고    scopus 로고
    • Suppression of streptococcal cell wall-induced arthritis by human chorionic gonadotropin
    • Song X.Y., Zeng L., Jin W., Pilo C.M., Frank M.E., Wahl S.M. Suppression of streptococcal cell wall-induced arthritis by human chorionic gonadotropin. Arthritis Rheum 2000, 43(9):2064-2072.
    • (2000) Arthritis Rheum , vol.43 , Issue.9 , pp. 2064-2072
    • Song, X.Y.1    Zeng, L.2    Jin, W.3    Pilo, C.M.4    Frank, M.E.5    Wahl, S.M.6
  • 28
    • 0032080572 scopus 로고    scopus 로고
    • An immunodominant epitope from mycobacterial 65-kDa heat shock protein protects against pristane-induced arthritis
    • Thompson S.J., Francis J.N., Siew L.K., Webb G.R., Jenner P.J., Colston M.J., et al. An immunodominant epitope from mycobacterial 65-kDa heat shock protein protects against pristane-induced arthritis. J Immunol 1998, 160(9):4628-4634.
    • (1998) J Immunol , vol.160 , Issue.9 , pp. 4628-4634
    • Thompson, S.J.1    Francis, J.N.2    Siew, L.K.3    Webb, G.R.4    Jenner, P.J.5    Colston, M.J.6
  • 29
    • 0030066630 scopus 로고    scopus 로고
    • A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis
    • Kingston A.E., Hicks C.A., Colston M.J., Billingham M.E. A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis. Clin Exp Immunol 1996, 103(1):77-82.
    • (1996) Clin Exp Immunol , vol.103 , Issue.1 , pp. 77-82
    • Kingston, A.E.1    Hicks, C.A.2    Colston, M.J.3    Billingham, M.E.4
  • 30
    • 0030953059 scopus 로고    scopus 로고
    • Peptide-induced nasal tolerance for a mycobacterial heat shock protein 60 T cell epitope in rats suppresses both adjuvant arthritis and nonmicrobially induced experimental arthritis
    • Prakken B.J., van der Zee R., Anderton S.M., van Kooten P.J., Kuis W., van Eden W. Peptide-induced nasal tolerance for a mycobacterial heat shock protein 60 T cell epitope in rats suppresses both adjuvant arthritis and nonmicrobially induced experimental arthritis. Proc Natl Acad Sci USA 1997, 94(7):3284-3289.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.7 , pp. 3284-3289
    • Prakken, B.J.1    van der Zee, R.2    Anderton, S.M.3    van Kooten, P.J.4    Kuis, W.5    van Eden, W.6
  • 31
    • 0034163391 scopus 로고    scopus 로고
    • A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-hsp70 homologue
    • Wendling U., Paul L., van der Zee R., Prakken B., Singh M., van Eden W. A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-hsp70 homologue. J Immunol 2000, 164(5):2711-2717.
    • (2000) J Immunol , vol.164 , Issue.5 , pp. 2711-2717
    • Wendling, U.1    Paul, L.2    van der Zee, R.3    Prakken, B.4    Singh, M.5    van Eden, W.6
  • 32
    • 8444238954 scopus 로고    scopus 로고
    • Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein
    • Quintana F.J., Carmi P., Mor F., Cohen I.R. Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein. Arthritis Rheum 2004, 50(11):3712-3720.
    • (2004) Arthritis Rheum , vol.50 , Issue.11 , pp. 3712-3720
    • Quintana, F.J.1    Carmi, P.2    Mor, F.3    Cohen, I.R.4
  • 33
    • 58249118715 scopus 로고    scopus 로고
    • Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-gamma, interleukin-17, and antibody responses
    • Satpute S.R., Rajaiah R., Polumuri S.K., Moudgil K.D. Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-gamma, interleukin-17, and antibody responses. Arthritis Rheum 2009, 60(1):103-113.
    • (2009) Arthritis Rheum , vol.60 , Issue.1 , pp. 103-113
    • Satpute, S.R.1    Rajaiah, R.2    Polumuri, S.K.3    Moudgil, K.D.4
  • 34
    • 0029937862 scopus 로고    scopus 로고
    • A synthetic 10-kD heat shock protein (hsp10) from Mycobacterium tuberculosis modulates adjuvant arthritis
    • Ragno S., Winrow V.R., Mascagni P., Lucietto P., Di Pierro F., Morris C.J., et al. A synthetic 10-kD heat shock protein (hsp10) from Mycobacterium tuberculosis modulates adjuvant arthritis. Clin Exp Immunol 1996, 103(3):384-390.
    • (1996) Clin Exp Immunol , vol.103 , Issue.3 , pp. 384-390
    • Ragno, S.1    Winrow, V.R.2    Mascagni, P.3    Lucietto, P.4    Di Pierro, F.5    Morris, C.J.6
  • 35
    • 0036175939 scopus 로고    scopus 로고
    • Preventive administration of Mycobacterium tuberculosis 10-kDa heat shock protein (hsp10) suppresses adjuvant arthritis in Lewis rats
    • Agnello D., Scanziani E., Di G.M., Leoni F., Modena D., Mascagni P., et al. Preventive administration of Mycobacterium tuberculosis 10-kDa heat shock protein (hsp10) suppresses adjuvant arthritis in Lewis rats. Int Immunopharmacol 2002, 2(4):463-474.
    • (2002) Int Immunopharmacol , vol.2 , Issue.4 , pp. 463-474
    • Agnello, D.1    Scanziani, E.2    Di, G.M.3    Leoni, F.4    Modena, D.5    Mascagni, P.6
  • 36
    • 33644910399 scopus 로고    scopus 로고
    • Treatment of murine collagen-induced arthritis by the stress protein BiP via interleukin-4-producing regulatory T cells: a novel function for an ancient protein
    • Brownlie R.J., Myers L.K., Wooley P.H., Corrigall V.M., Bodman-Smith M.D., Panayi G.S., et al. Treatment of murine collagen-induced arthritis by the stress protein BiP via interleukin-4-producing regulatory T cells: a novel function for an ancient protein. Arthritis Rheum 2006, 54(3):854-863.
    • (2006) Arthritis Rheum , vol.54 , Issue.3 , pp. 854-863
    • Brownlie, R.J.1    Myers, L.K.2    Wooley, P.H.3    Corrigall, V.M.4    Bodman-Smith, M.D.5    Panayi, G.S.6
  • 37
    • 0031920272 scopus 로고    scopus 로고
    • Gastric administration of recombinant 65 kDa heat shock protein delays the severity of type II collagen induced arthritis in mice
    • Jorgensen C., Gedon E., Jaquet C., Sany J. Gastric administration of recombinant 65 kDa heat shock protein delays the severity of type II collagen induced arthritis in mice. J Rheumatol 1998, 25(4):763-767.
    • (1998) J Rheumatol , vol.25 , Issue.4 , pp. 763-767
    • Jorgensen, C.1    Gedon, E.2    Jaquet, C.3    Sany, J.4
  • 38
    • 40949108072 scopus 로고    scopus 로고
    • Protective effects of overexpression TCR Vbeta5.2-HSP70 and TCR Vbeta8.2-HSP70 against collagen-induced arthritis in rats
    • Xiao J., Li S., Wang W., Li Y., Zhao W. Protective effects of overexpression TCR Vbeta5.2-HSP70 and TCR Vbeta8.2-HSP70 against collagen-induced arthritis in rats. Cell Mol Immunol 2007, 4(6):439-445.
    • (2007) Cell Mol Immunol , vol.4 , Issue.6 , pp. 439-445
    • Xiao, J.1    Li, S.2    Wang, W.3    Li, Y.4    Zhao, W.5
  • 39
    • 0028299971 scopus 로고
    • Differential mycobacterial 65-kDa heat shock protein T cell epitope recognition after adjuvant arthritis-inducing or protective immunization protocols
    • Anderton S.M., van der Zee R., Noordzij A., van Eden W. Differential mycobacterial 65-kDa heat shock protein T cell epitope recognition after adjuvant arthritis-inducing or protective immunization protocols. J Immunol 1994, 152(7):3656-3664.
    • (1994) J Immunol , vol.152 , Issue.7 , pp. 3656-3664
    • Anderton, S.M.1    van der Zee, R.2    Noordzij, A.3    van Eden, W.4
  • 40
    • 0028900289 scopus 로고
    • Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis
    • Anderton S.M., van der Zee R., Prakken B., Noordzij A., van Eden W. Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis. J Exp Med 1995, 181(3):943-952.
    • (1995) J Exp Med , vol.181 , Issue.3 , pp. 943-952
    • Anderton, S.M.1    van der Zee, R.2    Prakken, B.3    Noordzij, A.4    van Eden, W.5
  • 41
    • 2942741160 scopus 로고    scopus 로고
    • The regulatory C-terminal determinants within mycobacterial heat shock protein 65 are cryptic and cross-reactive with the dominant self homologs: implications for the pathogenesis of autoimmune arthritis
    • Durai M., Kim H.R., Moudgil K.D. The regulatory C-terminal determinants within mycobacterial heat shock protein 65 are cryptic and cross-reactive with the dominant self homologs: implications for the pathogenesis of autoimmune arthritis. J Immunol 2004, 173(1):181-188.
    • (2004) J Immunol , vol.173 , Issue.1 , pp. 181-188
    • Durai, M.1    Kim, H.R.2    Moudgil, K.D.3
  • 43
    • 1342324756 scopus 로고    scopus 로고
    • The T cells specific for the carboxyl-terminal determinants of self (rat) heat-shock protein 65 escape tolerance induction and are involved in regulation of autoimmune arthritis
    • Durai M., Gupta R.S., Moudgil K.D. The T cells specific for the carboxyl-terminal determinants of self (rat) heat-shock protein 65 escape tolerance induction and are involved in regulation of autoimmune arthritis. J Immunol 2004, 172(5):2795-2802.
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 2795-2802
    • Durai, M.1    Gupta, R.S.2    Moudgil, K.D.3
  • 44
    • 0025038041 scopus 로고
    • A mycobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic
    • Billingham M.E., Carney S., Butler R., Colston M.J. A mycobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic. J Exp Med 1990, 171(1):339-344.
    • (1990) J Exp Med , vol.171 , Issue.1 , pp. 339-344
    • Billingham, M.E.1    Carney, S.2    Butler, R.3    Colston, M.J.4
  • 45
    • 0021833728 scopus 로고
    • Reverse effect of gram-positive bacteria vs. gram-negative bacteria on adjuvant-induced arthritis in germfree rats
    • Kohashi O., Kohashi Y., Takahashi T., Ozawa A., Shigematsu N. Reverse effect of gram-positive bacteria vs. gram-negative bacteria on adjuvant-induced arthritis in germfree rats. Microbiol Immunol 1985, 29(6):487-497.
    • (1985) Microbiol Immunol , vol.29 , Issue.6 , pp. 487-497
    • Kohashi, O.1    Kohashi, Y.2    Takahashi, T.3    Ozawa, A.4    Shigematsu, N.5
  • 46
    • 0022597367 scopus 로고
    • Suppressive effect of Escherichia coli on adjuvant-induced arthritis in germ-free rats
    • Kohashi O., Kohashi Y., Takahashi T., Ozawa A., Shigematsu N. Suppressive effect of Escherichia coli on adjuvant-induced arthritis in germ-free rats. Arthritis Rheum 1986, 29(4):547-553.
    • (1986) Arthritis Rheum , vol.29 , Issue.4 , pp. 547-553
    • Kohashi, O.1    Kohashi, Y.2    Takahashi, T.3    Ozawa, A.4    Shigematsu, N.5
  • 47
    • 0029884944 scopus 로고    scopus 로고
    • HSP70-1 promoter region alleles and susceptibility to rheumatoid arthritis
    • Quadri S.A., Taneja V., Mehra N.K., Singal D.P. HSP70-1 promoter region alleles and susceptibility to rheumatoid arthritis. Clin Exp Rheumatol 1996, 14(2):183-185.
    • (1996) Clin Exp Rheumatol , vol.14 , Issue.2 , pp. 183-185
    • Quadri, S.A.1    Taneja, V.2    Mehra, N.K.3    Singal, D.P.4
  • 49
    • 0033877736 scopus 로고    scopus 로고
    • HLA class III region and susceptibility to rheumatoid arthritis
    • Singal D.P., Li J., Zhu Y. HLA class III region and susceptibility to rheumatoid arthritis. Clin Exp Rheumatol 2000, 18(4):485-491.
    • (2000) Clin Exp Rheumatol , vol.18 , Issue.4 , pp. 485-491
    • Singal, D.P.1    Li, J.2    Zhu, Y.3
  • 50
    • 55849140159 scopus 로고    scopus 로고
    • HMOX1 promoter polymorphism modulates the relationship between disease activity and joint damage in rheumatoid arthritis
    • Wagener F.A., Toonen E.J., Wigman L., Fransen J., Creemers M.C., Radstake T.R., et al. HMOX1 promoter polymorphism modulates the relationship between disease activity and joint damage in rheumatoid arthritis. Arthritis Rheum 2008, 58(11):3388-3393.
    • (2008) Arthritis Rheum , vol.58 , Issue.11 , pp. 3388-3393
    • Wagener, F.A.1    Toonen, E.J.2    Wigman, L.3    Fransen, J.4    Creemers, M.C.5    Radstake, T.R.6
  • 51
    • 0033941863 scopus 로고    scopus 로고
    • A novel variant of the MHC-linked hsp70, hsp70-hom, is associated with rheumatoid arthritis
    • Jenkins S.C., March R.E., Campbell R.D., Milner C.M. A novel variant of the MHC-linked hsp70, hsp70-hom, is associated with rheumatoid arthritis. Tissue Antigens 2000, 56(1):38-44.
    • (2000) Tissue Antigens , vol.56 , Issue.1 , pp. 38-44
    • Jenkins, S.C.1    March, R.E.2    Campbell, R.D.3    Milner, C.M.4
  • 52
    • 36448979908 scopus 로고    scopus 로고
    • HSPD1 is not a major susceptibility gene for rheumatoid arthritis in the French Caucasian population
    • Jacq L., Teixeira V.H., Garnier S., Michou L., Dieude P., Rocha D., et al. HSPD1 is not a major susceptibility gene for rheumatoid arthritis in the French Caucasian population. J Hum Genet 2007, 52(12):1036-1039.
    • (2007) J Hum Genet , vol.52 , Issue.12 , pp. 1036-1039
    • Jacq, L.1    Teixeira, V.H.2    Garnier, S.3    Michou, L.4    Dieude, P.5    Rocha, D.6
  • 54
    • 0029879122 scopus 로고    scopus 로고
    • HLA-DR4 and HLA-DR10 motifs that carry susceptibility to rheumatoid arthritis bind 70-kD heat shock proteins
    • Auger I., Escola J.M., Gorvel J.P., Roudier J. HLA-DR4 and HLA-DR10 motifs that carry susceptibility to rheumatoid arthritis bind 70-kD heat shock proteins. Nat Med 1996, 2(3):306-310.
    • (1996) Nat Med , vol.2 , Issue.3 , pp. 306-310
    • Auger, I.1    Escola, J.M.2    Gorvel, J.P.3    Roudier, J.4
  • 55
    • 0026503670 scopus 로고
    • The susceptibility sequence to rheumatoid arthritis is a cross-reactive B cell epitope shared by the Escherichia coli heat shock protein dnaJ and the histocompatibility leukocyte antigen DRB10401 molecule
    • Albani S., Tuckwell J.E., Esparza L., Carson D.A., Roudier J. The susceptibility sequence to rheumatoid arthritis is a cross-reactive B cell epitope shared by the Escherichia coli heat shock protein dnaJ and the histocompatibility leukocyte antigen DRB10401 molecule. J Clin Invest 1992, 89(1):327-331.
    • (1992) J Clin Invest , vol.89 , Issue.1 , pp. 327-331
    • Albani, S.1    Tuckwell, J.E.2    Esparza, L.3    Carson, D.A.4    Roudier, J.5
  • 56
    • 0036222543 scopus 로고    scopus 로고
    • Interaction between heat-shock protein 73 and HLA-DRB1 alleles associated or not with rheumatoid arthritis
    • Auger I., Lepecuchel L., Roudier J. Interaction between heat-shock protein 73 and HLA-DRB1 alleles associated or not with rheumatoid arthritis. Arthritis Rheum 2002, 46(4):929-933.
    • (2002) Arthritis Rheum , vol.46 , Issue.4 , pp. 929-933
    • Auger, I.1    Lepecuchel, L.2    Roudier, J.3
  • 57
    • 0030910370 scopus 로고    scopus 로고
    • A function for the QKRAA amino acid motif: mediating binding of DnaJ to DnaK. Implications for the association of rheumatoid arthritis with HLA-DR4
    • Auger I., Roudier J. A function for the QKRAA amino acid motif: mediating binding of DnaJ to DnaK. Implications for the association of rheumatoid arthritis with HLA-DR4. J Clin Invest 1997, 99(8):1818-1822.
    • (1997) J Clin Invest , vol.99 , Issue.8 , pp. 1818-1822
    • Auger, I.1    Roudier, J.2
  • 58
    • 0029078361 scopus 로고
    • Positive selection in autoimmunity: abnormal immune responses to a bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis
    • Albani S., Keystone E.C., Nelson J.L., Ollier W.E., La Cava A., Montemayor A.C., et al. Positive selection in autoimmunity: abnormal immune responses to a bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis. Nat Med 1995, 1(5):448-452.
    • (1995) Nat Med , vol.1 , Issue.5 , pp. 448-452
    • Albani, S.1    Keystone, E.C.2    Nelson, J.L.3    Ollier, W.E.4    La Cava, A.5    Montemayor, A.C.6
  • 59
    • 0036320489 scopus 로고    scopus 로고
    • Possible association of non-binding of HSP70 to HLA-DRB1 peptide sequences and protection from rheumatoid arthritis
    • Maier J.T., Haug M., Foll J.L., Beck H., Kalbacher H., Rammensee H.G., et al. Possible association of non-binding of HSP70 to HLA-DRB1 peptide sequences and protection from rheumatoid arthritis. Immunogenetics 2002, 54(2):67-73.
    • (2002) Immunogenetics , vol.54 , Issue.2 , pp. 67-73
    • Maier, J.T.1    Haug, M.2    Foll, J.L.3    Beck, H.4    Kalbacher, H.5    Rammensee, H.G.6
  • 60
    • 0141988655 scopus 로고    scopus 로고
    • Anti-inflammatory actions of the heme oxygenase-1 pathway
    • Alcaraz M.J., Fernandez P., Guillen M.I. Anti-inflammatory actions of the heme oxygenase-1 pathway. Curr Pharm Des 2003, 9(30):2541-2551.
    • (2003) Curr Pharm Des , vol.9 , Issue.30 , pp. 2541-2551
    • Alcaraz, M.J.1    Fernandez, P.2    Guillen, M.I.3
  • 61
    • 65249190995 scopus 로고    scopus 로고
    • Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling
    • Huang Q.Q., Sobkoviak R., Jockheck-Clark A.R., Shi B., Mandelin A.M., Tak P.P., et al. Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling. J Immunol 2009, 182(8):4965-4973.
    • (2009) J Immunol , vol.182 , Issue.8 , pp. 4965-4973
    • Huang, Q.Q.1    Sobkoviak, R.2    Jockheck-Clark, A.R.3    Shi, B.4    Mandelin, A.M.5    Tak, P.P.6
  • 62
    • 68549125086 scopus 로고    scopus 로고
    • Geranylgeranylacetone, a non-toxic inducer of heat shock protein, induces cell death in fibroblast-like synoviocytes from patients with rheumatoid arthritis
    • Nanke Y., Kawamoto M., Yago T., Chiba J., Yamanaka H., Kotake S. Geranylgeranylacetone, a non-toxic inducer of heat shock protein, induces cell death in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Mod Rheumatol 2009, 19(4):379-383.
    • (2009) Mod Rheumatol , vol.19 , Issue.4 , pp. 379-383
    • Nanke, Y.1    Kawamoto, M.2    Yago, T.3    Chiba, J.4    Yamanaka, H.5    Kotake, S.6
  • 63
    • 0026092378 scopus 로고
    • Stimulatory response towards the 65 kDa heat shock protein and other mycobacterial antigens in patients with rheumatoid arthritis
    • Burmester G.R., Altstidl U., Kalden J.R., Emmrich F. Stimulatory response towards the 65 kDa heat shock protein and other mycobacterial antigens in patients with rheumatoid arthritis. J Rheumatol 1991, 18(2):171-176.
    • (1991) J Rheumatol , vol.18 , Issue.2 , pp. 171-176
    • Burmester, G.R.1    Altstidl, U.2    Kalden, J.R.3    Emmrich, F.4
  • 64
    • 0030951653 scopus 로고    scopus 로고
    • Clonal expansion of mycobacterial heat-shock protein-reactive T lymphocytes in the synovial fluid and blood of rheumatoid arthritis patients
    • Celis L., Vandevyver C., Geusens P., Dequeker J., Raus J., Zhang J. Clonal expansion of mycobacterial heat-shock protein-reactive T lymphocytes in the synovial fluid and blood of rheumatoid arthritis patients. Arthritis Rheum 1997, 40(3):510-519.
    • (1997) Arthritis Rheum , vol.40 , Issue.3 , pp. 510-519
    • Celis, L.1    Vandevyver, C.2    Geusens, P.3    Dequeker, J.4    Raus, J.5    Zhang, J.6
  • 65
    • 0026052437 scopus 로고
    • Epitope specificity and MHC restriction of rheumatoid arthritis synovial T cell clones which recognize a mycobacterial 65 kDa heat shock protein
    • Gaston J.S., Life P.F., van der Zee R., Jenner P.J., Colston M.J., Tonks S., et al. Epitope specificity and MHC restriction of rheumatoid arthritis synovial T cell clones which recognize a mycobacterial 65 kDa heat shock protein. Int Immunol 1991, 3(10):965-972.
    • (1991) Int Immunol , vol.3 , Issue.10 , pp. 965-972
    • Gaston, J.S.1    Life, P.F.2    van der Zee, R.3    Jenner, P.J.4    Colston, M.J.5    Tonks, S.6
  • 66
    • 0027930534 scopus 로고
    • Proliferative response of synovial fluid mononuclear cells of patients with rheumatoid arthritis to mycobacterial 65 kDa heat shock protein and its association with HLA-DR+.gamma delta+ T cells
    • Kogure A., Miyata M., Nishimaki T., Kasukawa R. Proliferative response of synovial fluid mononuclear cells of patients with rheumatoid arthritis to mycobacterial 65 kDa heat shock protein and its association with HLA-DR+.gamma delta+ T cells. J Rheumatol 1994, 21(8):1403-1408.
    • (1994) J Rheumatol , vol.21 , Issue.8 , pp. 1403-1408
    • Kogure, A.1    Miyata, M.2    Nishimaki, T.3    Kasukawa, R.4
  • 67
    • 0029087847 scopus 로고
    • A dominant human leucocyte antigen DR4-Dw15 restricted mycobacterial 65 kDa antigen-specific T-cell immunity in Chinese patients with rheumatoid arthritis
    • Lai N.S., Lan J.L., Yu C.L., Lin R.H. A dominant human leucocyte antigen DR4-Dw15 restricted mycobacterial 65 kDa antigen-specific T-cell immunity in Chinese patients with rheumatoid arthritis. Br J Rheumatol 1995, 34(6):498-506.
    • (1995) Br J Rheumatol , vol.34 , Issue.6 , pp. 498-506
    • Lai, N.S.1    Lan, J.L.2    Yu, C.L.3    Lin, R.H.4
  • 68
    • 0033952924 scopus 로고    scopus 로고
    • Relationship between disease severity and responses by blood mononuclear cells from patients with rheumatoid arthritis to human heat-shock protein 60
    • MacHt L.M., Elson C.J., Kirwan J.R., Gaston J.S., Lamont A.G., Thompson J.M., et al. Relationship between disease severity and responses by blood mononuclear cells from patients with rheumatoid arthritis to human heat-shock protein 60. Immunology 2000, 99(2):208-214.
    • (2000) Immunology , vol.99 , Issue.2 , pp. 208-214
    • MacHt, L.M.1    Elson, C.J.2    Kirwan, J.R.3    Gaston, J.S.4    Lamont, A.G.5    Thompson, J.M.6
  • 69
    • 0030816441 scopus 로고    scopus 로고
    • Reactivity patterns of synovial T-cell lines derived from a patient with rheumatoid arthritis. I. Reactions with defined antigens and auto-antigens suggest the existence of multireactive T-cell clones
    • Melchers I., Jooss-Rudiger J., Peter H.H. Reactivity patterns of synovial T-cell lines derived from a patient with rheumatoid arthritis. I. Reactions with defined antigens and auto-antigens suggest the existence of multireactive T-cell clones. Scand J Immunol 1997, 46(2):187-194.
    • (1997) Scand J Immunol , vol.46 , Issue.2 , pp. 187-194
    • Melchers, I.1    Jooss-Rudiger, J.2    Peter, H.H.3
  • 70
    • 0026517450 scopus 로고
    • Activation of synovial fluid T lymphocytes by 60-kd heat-shock proteins in patients with inflammatory synovitis
    • Pope R.M., Lovis R.M., Gupta R.S. Activation of synovial fluid T lymphocytes by 60-kd heat-shock proteins in patients with inflammatory synovitis. Arthritis Rheum 1992, 35(1):43-48.
    • (1992) Arthritis Rheum , vol.35 , Issue.1 , pp. 43-48
    • Pope, R.M.1    Lovis, R.M.2    Gupta, R.S.3
  • 71
    • 0023768467 scopus 로고
    • Antibody levels to mycobacteria in relation to HLA type: evidence for non-HLA-linked high levels of antibody to the 65 kD heat shock protein of M. bovis in rheumatoid arthritis
    • Bahr G.M., Rook G.A., al-Saffar M., Van Embden J., Stanford J.L., Behbehani K. Antibody levels to mycobacteria in relation to HLA type: evidence for non-HLA-linked high levels of antibody to the 65 kD heat shock protein of M. bovis in rheumatoid arthritis. Clin Exp Immunol 1988, 74(2):211-215.
    • (1988) Clin Exp Immunol , vol.74 , Issue.2 , pp. 211-215
    • Bahr, G.M.1    Rook, G.A.2    al-Saffar, M.3    Van Embden, J.4    Stanford, J.L.5    Behbehani, K.6
  • 72
    • 0030739112 scopus 로고    scopus 로고
    • Stimulation of suppressive T cell responses by human but not bacterial 60-kD heat-shock protein in synovial fluid of patients with rheumatoid arthritis
    • van Roon J.A., van Eden W., van Roy J.L., Lafeber F.J., Bijlsma J.W. Stimulation of suppressive T cell responses by human but not bacterial 60-kD heat-shock protein in synovial fluid of patients with rheumatoid arthritis. J Clin Invest 1997, 100(2):459-463.
    • (1997) J Clin Invest , vol.100 , Issue.2 , pp. 459-463
    • van Roon, J.A.1    van Eden, W.2    van Roy, J.L.3    Lafeber, F.J.4    Bijlsma, J.W.5
  • 73
    • 0024444150 scopus 로고
    • In vitro responses to a 65-kilodalton mycobacterial protein by synovial T cells from inflammatory arthritis patients
    • Gaston J.S., Life P.F., Bailey L.C., Bacon P.A. In vitro responses to a 65-kilodalton mycobacterial protein by synovial T cells from inflammatory arthritis patients. J Immunol 1989, 143(8):2494-2500.
    • (1989) J Immunol , vol.143 , Issue.8 , pp. 2494-2500
    • Gaston, J.S.1    Life, P.F.2    Bailey, L.C.3    Bacon, P.A.4
  • 74
    • 0026558031 scopus 로고
    • Mycobacteria and human heat shock protein-specific cytotoxic T lymphocytes in rheumatoid synovial inflammation
    • Li S.G., Quayle A.J., Shen Y., Kjeldsen-Kragh J., Oftung F., Gupta R.S., et al. Mycobacteria and human heat shock protein-specific cytotoxic T lymphocytes in rheumatoid synovial inflammation. Arthritis Rheum 1992, 35(3):270-281.
    • (1992) Arthritis Rheum , vol.35 , Issue.3 , pp. 270-281
    • Li, S.G.1    Quayle, A.J.2    Shen, Y.3    Kjeldsen-Kragh, J.4    Oftung, F.5    Gupta, R.S.6
  • 75
    • 12144289938 scopus 로고    scopus 로고
    • Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis
    • Prakken B.J., Samodal R., Le T.D., Giannoni F., Yung G.P., Scavulli J., et al. Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis. Proc Natl Acad Sci USA 2004, 101(12):4228-4233.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.12 , pp. 4228-4233
    • Prakken, B.J.1    Samodal, R.2    Le, T.D.3    Giannoni, F.4    Yung, G.P.5    Scavulli, J.6
  • 76
    • 0035054076 scopus 로고    scopus 로고
    • The stress protein BiP is overexpressed and is a major B and T cell target in rheumatoid arthritis
    • Blass S., Union A., Raymackers J., Schumann F., Ungethum U., Muller-Steinbach S., et al. The stress protein BiP is overexpressed and is a major B and T cell target in rheumatoid arthritis. Arthritis Rheum 2001, 44(4):761-771.
    • (2001) Arthritis Rheum , vol.44 , Issue.4 , pp. 761-771
    • Blass, S.1    Union, A.2    Raymackers, J.3    Schumann, F.4    Ungethum, U.5    Muller-Steinbach, S.6
  • 77
    • 0035253485 scopus 로고    scopus 로고
    • The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis
    • Corrigall V.M., Bodman-Smith M.D., Fife M.S., Canas B., Myers L.K., Wooley P., et al. The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis. J Immunol 2001, 166(3):1492-1498.
    • (2001) J Immunol , vol.166 , Issue.3 , pp. 1492-1498
    • Corrigall, V.M.1    Bodman-Smith, M.D.2    Fife, M.S.3    Canas, B.4    Myers, L.K.5    Wooley, P.6
  • 78
    • 0036256921 scopus 로고    scopus 로고
    • T cell response to human HSP60 and yersinia 19 kDa in ankylosing spondylitis and rheumatoid arthritis: no evidence for a causal role of these antigens in the pathogenesis
    • Zou J., Rudwaleit M., Thiel A., Lauster R., Braun J., Sieper J. T cell response to human HSP60 and yersinia 19 kDa in ankylosing spondylitis and rheumatoid arthritis: no evidence for a causal role of these antigens in the pathogenesis. Ann Rheum Dis 2002, 61(5):473-474.
    • (2002) Ann Rheum Dis , vol.61 , Issue.5 , pp. 473-474
    • Zou, J.1    Rudwaleit, M.2    Thiel, A.3    Lauster, R.4    Braun, J.5    Sieper, J.6
  • 79
    • 0026683349 scopus 로고
    • Limiting-dilution analysis of T cell reactivity to mycobacterial antigens in peripheral blood and synovium from rheumatoid arthritis patients
    • Crick F.D., Gatenby P.A. Limiting-dilution analysis of T cell reactivity to mycobacterial antigens in peripheral blood and synovium from rheumatoid arthritis patients. Clin Exp Immunol 1992, 88(3):424-429.
    • (1992) Clin Exp Immunol , vol.88 , Issue.3 , pp. 424-429
    • Crick, F.D.1    Gatenby, P.A.2
  • 80
    • 0026010229 scopus 로고
    • Limiting dilution analysis of proliferative T cell responses to mycobacterial 65-kDa heat-shock protein fails to show significant frequency differences between synovial fluid and peripheral blood of patients with rheumatoid arthritis
    • Fischer H.P., Sharrock C.E., Colston M.J., Panayi G.S. Limiting dilution analysis of proliferative T cell responses to mycobacterial 65-kDa heat-shock protein fails to show significant frequency differences between synovial fluid and peripheral blood of patients with rheumatoid arthritis. Eur J Immunol 1991, 21(12):2937-2941.
    • (1991) Eur J Immunol , vol.21 , Issue.12 , pp. 2937-2941
    • Fischer, H.P.1    Sharrock, C.E.2    Colston, M.J.3    Panayi, G.S.4
  • 81
    • 42649086011 scopus 로고    scopus 로고
    • In-vitro effects of Mycobacterium bovis BCG-lysate and its derived heat shock proteins on cytokines secretion by blood mononuclear cells of rheumatoid arthritis patients in comparison with healthy controls
    • Sheikhi A., Nazarian M., Khadem-Al-Melleh A., Nasab N.M., Esmaeilzadeh A., Yahaghi N., et al. In-vitro effects of Mycobacterium bovis BCG-lysate and its derived heat shock proteins on cytokines secretion by blood mononuclear cells of rheumatoid arthritis patients in comparison with healthy controls. Int Immunopharmacol 2008, 8(6):887-892.
    • (2008) Int Immunopharmacol , vol.8 , Issue.6 , pp. 887-892
    • Sheikhi, A.1    Nazarian, M.2    Khadem-Al-Melleh, A.3    Nasab, N.M.4    Esmaeilzadeh, A.5    Yahaghi, N.6
  • 82
    • 0033053107 scopus 로고    scopus 로고
    • Isolation of an IgG monoclonal anti-dnaJ antibody from an immunoglobulin combinatorial library from a patient with rheumatoid arthritis
    • Chukwuocha R.U., Zhang B., Lai C.J., Scavulli J.F., Albani S., Carson D.A., et al. Isolation of an IgG monoclonal anti-dnaJ antibody from an immunoglobulin combinatorial library from a patient with rheumatoid arthritis. J Rheumatol 1999, 26(7):1439-1445.
    • (1999) J Rheumatol , vol.26 , Issue.7 , pp. 1439-1445
    • Chukwuocha, R.U.1    Zhang, B.2    Lai, C.J.3    Scavulli, J.F.4    Albani, S.5    Carson, D.A.6
  • 83
    • 0034989792 scopus 로고    scopus 로고
    • Immunodominant region of Actinobacillus actinomycetemcomitans 40-kilodalton heat shock protein in patients with rheumatoid arthritis
    • Yoshida A., Nakano Y., Yamashita Y., Oho T., Ito H., Kondo M., et al. Immunodominant region of Actinobacillus actinomycetemcomitans 40-kilodalton heat shock protein in patients with rheumatoid arthritis. J Dent Res 2001, 80(1):346-350.
    • (2001) J Dent Res , vol.80 , Issue.1 , pp. 346-350
    • Yoshida, A.1    Nakano, Y.2    Yamashita, Y.3    Oho, T.4    Ito, H.5    Kondo, M.6
  • 84
    • 0033773162 scopus 로고    scopus 로고
    • Rheumatoid arthritis-related antigen 47kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47
    • Hattori T., Takahash K., Yutani Y., Fujisawa T., Nakanishi T., Takigawa M. Rheumatoid arthritis-related antigen 47kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47. J Bone Miner Metab 2000, 18(6):328-334.
    • (2000) J Bone Miner Metab , vol.18 , Issue.6 , pp. 328-334
    • Hattori, T.1    Takahash, K.2    Yutani, Y.3    Fujisawa, T.4    Nakanishi, T.5    Takigawa, M.6
  • 85
    • 0000609230 scopus 로고    scopus 로고
    • Specific serum antibodies against membranous proteins of a human immortal chondrocytic cell line (HCS-2/8) in rheumatoid arthritis and their relationship to the natural history of this disease
    • Sakawa A., Yutani Y., Inui K., Shimazu A., Yamano Y., Kinosita A., et al. Specific serum antibodies against membranous proteins of a human immortal chondrocytic cell line (HCS-2/8) in rheumatoid arthritis and their relationship to the natural history of this disease. J Bone Miner Metab 1996, 14(3):146-152.
    • (1996) J Bone Miner Metab , vol.14 , Issue.3 , pp. 146-152
    • Sakawa, A.1    Yutani, Y.2    Inui, K.3    Shimazu, A.4    Yamano, Y.5    Kinosita, A.6
  • 86
    • 0024437225 scopus 로고
    • Elevated IgG antibody levels to the mycobacterial 65-kDa heat shock protein are characteristic of patients with rheumatoid arthritis
    • Tsoulfa G., Rook G.A., Bahr G.M., Sattar M.A., Behbehani K., Young D.B., et al. Elevated IgG antibody levels to the mycobacterial 65-kDa heat shock protein are characteristic of patients with rheumatoid arthritis. Scand J Immunol 1989, 30(5):519-527.
    • (1989) Scand J Immunol , vol.30 , Issue.5 , pp. 519-527
    • Tsoulfa, G.1    Rook, G.A.2    Bahr, G.M.3    Sattar, M.A.4    Behbehani, K.5    Young, D.B.6
  • 87
    • 0028989166 scopus 로고
    • Antibodies to the 65 kDa mycobacterial stress protein in west Africans with rheumatoid arthritis, tuberculosis and malaria
    • Adebajo A.O., Williams D.G., Hazleman B.L., Maini R.N. Antibodies to the 65 kDa mycobacterial stress protein in west Africans with rheumatoid arthritis, tuberculosis and malaria. Br J Rheumatol 1995, 34(4):352-354.
    • (1995) Br J Rheumatol , vol.34 , Issue.4 , pp. 352-354
    • Adebajo, A.O.1    Williams, D.G.2    Hazleman, B.L.3    Maini, R.N.4
  • 88
    • 0031081249 scopus 로고    scopus 로고
    • Preferential binding with Escherichia coli hsp60 of antibodies prevalent in sera from patients with rheumatoid arthritis
    • Hirata D., Hirai I., Iwamoto M., Yoshio T., Takeda A., Masuyama J.I., et al. Preferential binding with Escherichia coli hsp60 of antibodies prevalent in sera from patients with rheumatoid arthritis. Clin Immunol Immunopathol 1997, 82(2):141-148.
    • (1997) Clin Immunol Immunopathol , vol.82 , Issue.2 , pp. 141-148
    • Hirata, D.1    Hirai, I.2    Iwamoto, M.3    Yoshio, T.4    Takeda, A.5    Masuyama, J.I.6
  • 89
    • 0026448823 scopus 로고
    • Antibodies to 65 kDa and 70 kDa heat shock proteins in rheumatoid arthritis and systemic lupus erythematosus
    • Panchapakesan J., Daglis M., Gatenby P. Antibodies to 65 kDa and 70 kDa heat shock proteins in rheumatoid arthritis and systemic lupus erythematosus. Immunol Cell Biol 1992, 70(Pt. 5):295-300.
    • (1992) Immunol Cell Biol , vol.70 , Issue.PART. 5 , pp. 295-300
    • Panchapakesan, J.1    Daglis, M.2    Gatenby, P.3
  • 90
    • 0030955267 scopus 로고    scopus 로고
    • The B cell repertoire of patients with rheumatoid arthritis. II. Increased frequencies of IgG+ and IgA+ B cells specific for mycobacterial heat-shock protein 60 or human type II collagen in synovial fluid and tissue
    • Rudolphi U., Rzepka R., Batsford S., Kaufmann S.H., von der Mark K., Peter H.H., et al. The B cell repertoire of patients with rheumatoid arthritis. II. Increased frequencies of IgG+ and IgA+ B cells specific for mycobacterial heat-shock protein 60 or human type II collagen in synovial fluid and tissue. Arthritis Rheum 1997, 40(8):1409-1419.
    • (1997) Arthritis Rheum , vol.40 , Issue.8 , pp. 1409-1419
    • Rudolphi, U.1    Rzepka, R.2    Batsford, S.3    Kaufmann, S.H.4    von der Mark, K.5    Peter, H.H.6
  • 91
    • 33646255457 scopus 로고    scopus 로고
    • Antibodies against human 60 kDa heat shock protein are not associated with cardiovascular disease in patients with rheumatoid arthritis
    • van Halm V.P., Slot M.C., Nurmohamed M.T., Cohen Tervaert J.W., Dijkmans B.A., Voskuyl A.E. Antibodies against human 60 kDa heat shock protein are not associated with cardiovascular disease in patients with rheumatoid arthritis. Ann Rheum Dis 2006, 65(5):590-594.
    • (2006) Ann Rheum Dis , vol.65 , Issue.5 , pp. 590-594
    • van Halm, V.P.1    Slot, M.C.2    Nurmohamed, M.T.3    Cohen Tervaert, J.W.4    Dijkmans, B.A.5    Voskuyl, A.E.6
  • 92
    • 0028243235 scopus 로고
    • Antibodies to 65Kd heat-shock protein were elevated in rheumatoid arthritis
    • Oda A., Miyata M., Kodama E., Satoh H., Sato Y., Nishimaki T., et al. Antibodies to 65Kd heat-shock protein were elevated in rheumatoid arthritis. Clin Rheumatol 1994, 13(2):261-264.
    • (1994) Clin Rheumatol , vol.13 , Issue.2 , pp. 261-264
    • Oda, A.1    Miyata, M.2    Kodama, E.3    Satoh, H.4    Sato, Y.5    Nishimaki, T.6
  • 93
    • 27744446060 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis
    • Mavropoulos J.C., Cuchacovich M., Llanos C., Aguillon J.C., Gatica H., Pizzo S.V., et al. Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis. J Rheumatol 2005, 32(11):2116-2124.
    • (2005) J Rheumatol , vol.32 , Issue.11 , pp. 2116-2124
    • Mavropoulos, J.C.1    Cuchacovich, M.2    Llanos, C.3    Aguillon, J.C.4    Gatica, H.5    Pizzo, S.V.6
  • 94
    • 0032928895 scopus 로고    scopus 로고
    • Anti-heat shock protein 70 kDa and 90 kDa antibodies in serum of patients with rheumatoid arthritis
    • Hayem G., De Bandt M., Palazzo E., Roux S., Combe B., Eliaou J.F., et al. Anti-heat shock protein 70 kDa and 90 kDa antibodies in serum of patients with rheumatoid arthritis. Ann Rheum Dis 1999, 58(5):291-296.
    • (1999) Ann Rheum Dis , vol.58 , Issue.5 , pp. 291-296
    • Hayem, G.1    De Bandt, M.2    Palazzo, E.3    Roux, S.4    Combe, B.5    Eliaou, J.F.6
  • 95
    • 0025615210 scopus 로고
    • Specific antibody response to the mycobacterial 65 kDa stress protein in ankylosing spondylitis and rheumatoid arthritis
    • McLean I.L., Archer J.R., Cawley M.I., Pegley F.S., Kidd B.L., Thompson P.W. Specific antibody response to the mycobacterial 65 kDa stress protein in ankylosing spondylitis and rheumatoid arthritis. Br J Rheumatol 1990, 29(6):426-429.
    • (1990) Br J Rheumatol , vol.29 , Issue.6 , pp. 426-429
    • McLean, I.L.1    Archer, J.R.2    Cawley, M.I.3    Pegley, F.S.4    Kidd, B.L.5    Thompson, P.W.6
  • 96
    • 0027167551 scopus 로고
    • The B cell repertoire of patients with rheumatoid arthritis. Frequencies and specificities of peripheral blood B cells reacting with human IgG, human collagens, a mycobacterial heat shock protein and other antigens
    • Rudolphi U., Hohlbaum A., Lang B., Peter H.H., Melchers I. The B cell repertoire of patients with rheumatoid arthritis. Frequencies and specificities of peripheral blood B cells reacting with human IgG, human collagens, a mycobacterial heat shock protein and other antigens. Clin Exp Immunol 1993, 92(3):404-411.
    • (1993) Clin Exp Immunol , vol.92 , Issue.3 , pp. 404-411
    • Rudolphi, U.1    Hohlbaum, A.2    Lang, B.3    Peter, H.H.4    Melchers, I.5
  • 97
    • 34948856922 scopus 로고    scopus 로고
    • Heat-shock protein 65 autoantibodies are differently associated with early atherosclerosis in rheumatoid arthritis and in healthy subjects
    • Sherer Y., Gerli R., Bocci E.B., Gilburd B., Vaudo G., Bistoni O., et al. Heat-shock protein 65 autoantibodies are differently associated with early atherosclerosis in rheumatoid arthritis and in healthy subjects. Ann NY Acad Sci 2007, 1108:408-413.
    • (2007) Ann NY Acad Sci , vol.1108 , pp. 408-413
    • Sherer, Y.1    Gerli, R.2    Bocci, E.B.3    Gilburd, B.4    Vaudo, G.5    Bistoni, O.6
  • 98
    • 0027203193 scopus 로고
    • Lack of association of increased antibody levels to mycobacterial hsp65 with rheumatoid arthritis: results from a study of disease discordant twin pairs
    • Worthington J., Rigby A.S., MacGregor A.J., Silman A.J., Carthy D., Ollier W.E. Lack of association of increased antibody levels to mycobacterial hsp65 with rheumatoid arthritis: results from a study of disease discordant twin pairs. Ann Rheum Dis 1993, 52(7):542-544.
    • (1993) Ann Rheum Dis , vol.52 , Issue.7 , pp. 542-544
    • Worthington, J.1    Rigby, A.S.2    MacGregor, A.J.3    Silman, A.J.4    Carthy, D.5    Ollier, W.E.6
  • 99
    • 33646882893 scopus 로고    scopus 로고
    • Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis
    • Roelofs M.F., Boelens W.C., Joosten L.A., Abdollahi-Roodsaz S., Geurts J., Wunderink L.U., et al. Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis. J Immunol 2006, 176(11):7021-7027.
    • (2006) J Immunol , vol.176 , Issue.11 , pp. 7021-7027
    • Roelofs, M.F.1    Boelens, W.C.2    Joosten, L.A.3    Abdollahi-Roodsaz, S.4    Geurts, J.5    Wunderink, L.U.6
  • 100
    • 54349105949 scopus 로고    scopus 로고
    • Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination
    • Kidd B.A., Ho P.P., Sharpe O., Zhao X., Tomooka B.H., Kanter J.L., et al. Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination. Arthritis Res Ther 2008, 10(5):R119.
    • (2008) Arthritis Res Ther , vol.10 , Issue.5
    • Kidd, B.A.1    Ho, P.P.2    Sharpe, O.3    Zhao, X.4    Tomooka, B.H.5    Kanter, J.L.6
  • 102
    • 33645345411 scopus 로고    scopus 로고
    • Anti-CCP antibodies measured at disease onset help identify seronegative rheumatoid arthritis and predict radiological and functional outcome
    • Quinn M.A., Gough A.K., Green M.J., Devlin J., Hensor E.M., Greenstein A., et al. Anti-CCP antibodies measured at disease onset help identify seronegative rheumatoid arthritis and predict radiological and functional outcome. Rheumatology (Oxford) 2006, 45(4):478-480.
    • (2006) Rheumatology (Oxford) , vol.45 , Issue.4 , pp. 478-480
    • Quinn, M.A.1    Gough, A.K.2    Green, M.J.3    Devlin, J.4    Hensor, E.M.5    Greenstein, A.6
  • 103
    • 33646367148 scopus 로고    scopus 로고
    • Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis
    • Kobayashi H., Takeno M., Saito T., Takeda Y., Kirino Y., Noyori K., et al. Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis. Arthritis Rheum 2006, 54(4):1132-1142.
    • (2006) Arthritis Rheum , vol.54 , Issue.4 , pp. 1132-1142
    • Kobayashi, H.1    Takeno, M.2    Saito, T.3    Takeda, Y.4    Kirino, Y.5    Noyori, K.6
  • 104
    • 33747881274 scopus 로고    scopus 로고
    • Therapeutic efficacy and safety of chaperonin 10 in patients with rheumatoid arthritis: a double-blind randomised trial
    • Vanags D., Williams B., Johnson B., Hall S., Nash P., Taylor A., et al. Therapeutic efficacy and safety of chaperonin 10 in patients with rheumatoid arthritis: a double-blind randomised trial. Lancet 2006, 368(9538):855-863.
    • (2006) Lancet , vol.368 , Issue.9538 , pp. 855-863
    • Vanags, D.1    Williams, B.2    Johnson, B.3    Hall, S.4    Nash, P.5    Taylor, A.6
  • 105
    • 20044370433 scopus 로고    scopus 로고
    • Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production
    • Johnson B.J., Le T.T., Dobbin C.A., Banovic T., Howard C.B., Flores Fde M., et al. Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production. J Biol Chem 2005, 280(6):4037-4047.
    • (2005) J Biol Chem , vol.280 , Issue.6 , pp. 4037-4047
    • Johnson, B.J.1    Le, T.T.2    Dobbin, C.A.3    Banovic, T.4    Howard, C.B.5    Flores Fde, M.6
  • 106
    • 77957020725 scopus 로고    scopus 로고
    • Susceptibility to epitope specific immunotherapy of rheumatoid arthritis relies on the expression of co-stimulatory molecules associated with T cells anergy and tolerance (Abstract number 1848), Abstract supplement 2008 Annual Scientific Meeting
    • van den Broek T.K.E., van Wijk F., Ghahramani N., Schechter N., van de Ven A., Albani S. Susceptibility to epitope specific immunotherapy of rheumatoid arthritis relies on the expression of co-stimulatory molecules associated with T cells anergy and tolerance (Abstract number 1848), Abstract supplement 2008 Annual Scientific Meeting. Arthritis Rheum 2008, 58(Suppl 9):845.
    • (2008) Arthritis Rheum , vol.58 , Issue.SUPPL. 9 , pp. 845
    • van den Broek, T.K.E.1    van Wijk, F.2    Ghahramani, N.3    Schechter, N.4    van de Ven, A.5    Albani, S.6
  • 107
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy
    • Ehrenstein M.R., Evans J.G., Singh A., Moore S., Warnes G., Isenberg D.A., et al. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. J Exp Med 2004, 200(3):277-285.
    • (2004) J Exp Med , vol.200 , Issue.3 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5    Isenberg, D.A.6
  • 108
    • 33745817772 scopus 로고    scopus 로고
    • Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling
    • Zanin-Zhorov A., Cahalon L., Tal G., Margalit R., Lider O., Cohen I.R. Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling. J Clin Invest 2006, 116(7):2022-2032.
    • (2006) J Clin Invest , vol.116 , Issue.7 , pp. 2022-2032
    • Zanin-Zhorov, A.1    Cahalon, L.2    Tal, G.3    Margalit, R.4    Lider, O.5    Cohen, I.R.6
  • 109
    • 0025844958 scopus 로고
    • Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis
    • De Graeff-Meeder E.R., van der Zee R., Rijkers G.T., Schuurman H.J., Kuis W., Bijlsma J.W., et al. Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis. Lancet 1991, 337(8754):1368-1372.
    • (1991) Lancet , vol.337 , Issue.8754 , pp. 1368-1372
    • De Graeff-Meeder, E.R.1    van der Zee, R.2    Rijkers, G.T.3    Schuurman, H.J.4    Kuis, W.5    Bijlsma, J.W.6
  • 110
    • 0028909538 scopus 로고
    • Juvenile chronic arthritis: T cell reactivity to human HSP60 in patients with a favorable course of arthritis
    • de Graeff-Meeder E.R., van Eden W., Rijkers G.T., Prakken B.J., Kuis W., Voorhorst-Ogink M.M., et al. Juvenile chronic arthritis: T cell reactivity to human HSP60 in patients with a favorable course of arthritis. J Clin Invest 1995, 95(3):934-940.
    • (1995) J Clin Invest , vol.95 , Issue.3 , pp. 934-940
    • de Graeff-Meeder, E.R.1    van Eden, W.2    Rijkers, G.T.3    Prakken, B.J.4    Kuis, W.5    Voorhorst-Ogink, M.M.6
  • 111
    • 0038681274 scopus 로고    scopus 로고
    • The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T cells directed to human heat-shock protein 60 capable of producing the regulatory cytokine interleukin-10
    • de Kleer I.M., Kamphuis S.M., Rijkers G.T., Scholtens L., Gordon G., De Jager W., et al. The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T cells directed to human heat-shock protein 60 capable of producing the regulatory cytokine interleukin-10. Arthritis Rheum 2003, 48(7):2001-2010.
    • (2003) Arthritis Rheum , vol.48 , Issue.7 , pp. 2001-2010
    • de Kleer, I.M.1    Kamphuis, S.M.2    Rijkers, G.T.3    Scholtens, L.4    Gordon, G.5    De Jager, W.6
  • 112
    • 0029911403 scopus 로고    scopus 로고
    • Autoreactivity to human heat-shock protein 60 predicts disease remission in oligoarticular juvenile rheumatoid arthritis
    • Prakken A.B., van Eden W., Rijkers G.T., Kuis W., Toebes E.A., de Graeff-Meeder E.R., et al. Autoreactivity to human heat-shock protein 60 predicts disease remission in oligoarticular juvenile rheumatoid arthritis. Arthritis Rheum 1996, 39(11):1826-1832.
    • (1996) Arthritis Rheum , vol.39 , Issue.11 , pp. 1826-1832
    • Prakken, A.B.1    van Eden, W.2    Rijkers, G.T.3    Kuis, W.4    Toebes, E.A.5    de Graeff-Meeder, E.R.6
  • 113
    • 73349110416 scopus 로고    scopus 로고
    • The determinants of susceptibility/resistance to adjuvant arthritis in rats
    • Kim E.Y., Moudgil K.D. The determinants of susceptibility/resistance to adjuvant arthritis in rats. Arthritis Res Ther 2009, 11(4):239.
    • (2009) Arthritis Res Ther , vol.11 , Issue.4 , pp. 239
    • Kim, E.Y.1    Moudgil, K.D.2
  • 114
    • 49049110038 scopus 로고    scopus 로고
    • Commensal gut bacteria and the etiopathogenesis of rheumatoid arthritis
    • Edwards C.J. Commensal gut bacteria and the etiopathogenesis of rheumatoid arthritis. J Rheumatol 2008, 35(8):1477-1497.
    • (2008) J Rheumatol , vol.35 , Issue.8 , pp. 1477-1497
    • Edwards, C.J.1
  • 115
    • 48249156638 scopus 로고    scopus 로고
    • What is the role of the metabolic activity of the gut microbiota in inflammatory bowel disease?. Probing for answers with stable isotopes
    • Barclay A.R., Morrison D.J., Weaver L.T. What is the role of the metabolic activity of the gut microbiota in inflammatory bowel disease?. Probing for answers with stable isotopes. J Pediatr Gastroenterol Nutr 2008, 46(5):486-495.
    • (2008) J Pediatr Gastroenterol Nutr , vol.46 , Issue.5 , pp. 486-495
    • Barclay, A.R.1    Morrison, D.J.2    Weaver, L.T.3
  • 117
    • 0027415058 scopus 로고
    • Influence of the bacterial flora on collagen-induced arthritis in susceptible and resistant strains of rats
    • Breban M.A., Moreau M.C., Fournier C., Ducluzeau R., Kahn M.F. Influence of the bacterial flora on collagen-induced arthritis in susceptible and resistant strains of rats. Clin Exp Rheumatol 1993, 11(1):61-64.
    • (1993) Clin Exp Rheumatol , vol.11 , Issue.1 , pp. 61-64
    • Breban, M.A.1    Moreau, M.C.2    Fournier, C.3    Ducluzeau, R.4    Kahn, M.F.5
  • 118
    • 0035869304 scopus 로고    scopus 로고
    • Environmental modulation of autoimmune arthritis involves the spontaneous microbial induction of T cell responses to regulatory determinants within heat shock protein 65
    • Moudgil K.D., Kim E., Yun O.J., Chi H.H., Brahn E., Sercarz E.E. Environmental modulation of autoimmune arthritis involves the spontaneous microbial induction of T cell responses to regulatory determinants within heat shock protein 65. J Immunol 2001, 166(6):4237-4243.
    • (2001) J Immunol , vol.166 , Issue.6 , pp. 4237-4243
    • Moudgil, K.D.1    Kim, E.2    Yun, O.J.3    Chi, H.H.4    Brahn, E.5    Sercarz, E.E.6
  • 119
    • 0035082966 scopus 로고    scopus 로고
    • Influence of major histocompatibility complex on bacterial composition of fecal flora
    • Toivanen P., Vaahtovuo J., Eerola E. Influence of major histocompatibility complex on bacterial composition of fecal flora. Infect Immun 2001, 69(4):2372-2377.
    • (2001) Infect Immun , vol.69 , Issue.4 , pp. 2372-2377
    • Toivanen, P.1    Vaahtovuo, J.2    Eerola, E.3
  • 121
    • 70149096873 scopus 로고    scopus 로고
    • Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
    • Clayton T.A., Baker D., Lindon J.C., Everett J.R., Nicholson J.K. Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proc Natl Acad Sci USA 2009, 106(34):14728-14733.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.34 , pp. 14728-14733
    • Clayton, T.A.1    Baker, D.2    Lindon, J.C.3    Everett, J.R.4    Nicholson, J.K.5
  • 122
    • 0025809894 scopus 로고
    • Modulation of experimental autoimmunity: treatment of adjuvant arthritis by immunization with a recombinant vaccinia virus
    • Hogervorst E.J., Schouls L., Wagenaar J.P., Boog C.J., Spaan W.J., et al. Modulation of experimental autoimmunity: treatment of adjuvant arthritis by immunization with a recombinant vaccinia virus. Infect Immun 1991, 59(6):2029-2035.
    • (1991) Infect Immun , vol.59 , Issue.6 , pp. 2029-2035
    • Hogervorst, E.J.1    Schouls, L.2    Wagenaar, J.P.3    Boog, C.J.4    Spaan, W.J.5
  • 124
    • 0030859414 scopus 로고    scopus 로고
    • Experimental immunization with anti-rheumatic bacterial extract OM-89 induces T cell responses to heat shock protein (hsp)60 and hsp70; modulation of peripheral immunological tolerance as its possible mode of action in the treatment of rheumatoid arthritis (RA)
    • Bloemendal A., Van der Zee R., Rutten V.P., van Kooten P.J., Farine J.C., van Eden W. Experimental immunization with anti-rheumatic bacterial extract OM-89 induces T cell responses to heat shock protein (hsp)60 and hsp70; modulation of peripheral immunological tolerance as its possible mode of action in the treatment of rheumatoid arthritis (RA). Clin Exp Immunol 1997, 110(1):72-78.
    • (1997) Clin Exp Immunol , vol.110 , Issue.1 , pp. 72-78
    • Bloemendal, A.1    Van der Zee, R.2    Rutten, V.P.3    van Kooten, P.J.4    Farine, J.C.5    van Eden, W.6
  • 125
    • 0028079811 scopus 로고
    • Therapeutic effect of recombinant vaccinia virus expressing the 60-kd heat-shock protein on adjuvant arthritis
    • Lopez-Guerrero J.A., Ortiz M.A., Paez E., Bernabeu C., Lopez-Bote J.P. Therapeutic effect of recombinant vaccinia virus expressing the 60-kd heat-shock protein on adjuvant arthritis. Arthritis Rheum 1994, 37(10):1462-1467.
    • (1994) Arthritis Rheum , vol.37 , Issue.10 , pp. 1462-1467
    • Lopez-Guerrero, J.A.1    Ortiz, M.A.2    Paez, E.3    Bernabeu, C.4    Lopez-Bote, J.P.5
  • 126
    • 0035887917 scopus 로고    scopus 로고
    • Induction of IL-10 and inhibition of experimental arthritis are specific features of microbial heat shock proteins that are absent for other evolutionarily conserved immunodominant proteins
    • Prakken B.J., Wendling U., van der Zee R., Rutten V.P., Kuis W., van Eden W. Induction of IL-10 and inhibition of experimental arthritis are specific features of microbial heat shock proteins that are absent for other evolutionarily conserved immunodominant proteins. J Immunol 2001, 167(8):4147-4153.
    • (2001) J Immunol , vol.167 , Issue.8 , pp. 4147-4153
    • Prakken, B.J.1    Wendling, U.2    van der Zee, R.3    Rutten, V.P.4    Kuis, W.5    van Eden, W.6
  • 127
    • 0032959003 scopus 로고    scopus 로고
    • Immunosuppressive effects of the heat shock protein 90-binding antibiotic geldanamycin
    • Sugita T., Tanaka S., Murakami T., Miyoshi H., Ohnuki T. Immunosuppressive effects of the heat shock protein 90-binding antibiotic geldanamycin. Biochem Mol Biol Int 1999, 47(4):587-595.
    • (1999) Biochem Mol Biol Int , vol.47 , Issue.4 , pp. 587-595
    • Sugita, T.1    Tanaka, S.2    Murakami, T.3    Miyoshi, H.4    Ohnuki, T.5
  • 128
    • 0027052019 scopus 로고
    • Differential effects of immunisation with mycobacterial 65 kD heat shock protein on two models of autoimmunity
    • Barker R.N., Webb G.R., Thompson S.J., Ghoraishian M., Ponsford F.M., Elson C.J. Differential effects of immunisation with mycobacterial 65 kD heat shock protein on two models of autoimmunity. Autoimmunity 1992, 14(1):73-77.
    • (1992) Autoimmunity , vol.14 , Issue.1 , pp. 73-77
    • Barker, R.N.1    Webb, G.R.2    Thompson, S.J.3    Ghoraishian, M.4    Ponsford, F.M.5    Elson, C.J.6
  • 129
    • 0031572512 scopus 로고    scopus 로고
    • CD4+ Th2 cells specific for mycobacterial 65-kilodalton heat shock protein protect against pristine-induced arthritis
    • Beech J.T., Siew L.K., Ghoraishian M., Stasiuk L.M., Elson C.J., Thompson S.J. CD4+ Th2 cells specific for mycobacterial 65-kilodalton heat shock protein protect against pristine-induced arthritis. J Immunol 1997, 159(8):3692-3697.
    • (1997) J Immunol , vol.159 , Issue.8 , pp. 3692-3697
    • Beech, J.T.1    Siew, L.K.2    Ghoraishian, M.3    Stasiuk, L.M.4    Elson, C.J.5    Thompson, S.J.6
  • 130
    • 0027491478 scopus 로고
    • Comparison between the protective effects of mycobacterial 65-kD heat shock protein and ovomucoid in pristane-induced arthritis: relationship with agalactosyl IgG
    • Ghoraishian M., Elson C.J., Thompson S.J. Comparison between the protective effects of mycobacterial 65-kD heat shock protein and ovomucoid in pristane-induced arthritis: relationship with agalactosyl IgG. Clin Exp Immunol 1993, 94(2):247-251.
    • (1993) Clin Exp Immunol , vol.94 , Issue.2 , pp. 247-251
    • Ghoraishian, M.1    Elson, C.J.2    Thompson, S.J.3
  • 131
  • 132
    • 0026319673 scopus 로고
    • Cellular and humoral reactivity pattern to the mycobacterial heat shock protein hsp65 in pristane induced arthritis susceptible and hsp65 protected DBA/1 mice
    • Thompson S.J., Hitsumoto Y., Ghoraishian M., van der Zee R., Elson C.J. Cellular and humoral reactivity pattern to the mycobacterial heat shock protein hsp65 in pristane induced arthritis susceptible and hsp65 protected DBA/1 mice. Autoimmunity 1991, 11(2):89-95.
    • (1991) Autoimmunity , vol.11 , Issue.2 , pp. 89-95
    • Thompson, S.J.1    Hitsumoto, Y.2    Ghoraishian, M.3    van der Zee, R.4    Elson, C.J.5
  • 133
    • 0029611709 scopus 로고
    • Polyarthritis in the rat: effects of tolerance and sensitization to the bacterial extract OM-89 with a possible mode of action
    • Willis D., Moore A.R., Gowland G., Willoughby A. Polyarthritis in the rat: effects of tolerance and sensitization to the bacterial extract OM-89 with a possible mode of action. Br J Rheumatol 1995, 34(12):1135-1138.
    • (1995) Br J Rheumatol , vol.34 , Issue.12 , pp. 1135-1138
    • Willis, D.1    Moore, A.R.2    Gowland, G.3    Willoughby, A.4
  • 134
    • 58449116889 scopus 로고    scopus 로고
    • IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis
    • Wieten L., Berlo S.E., Ten Brink C.B., van Kooten P.J., Singh M., van der Zee R., et al. IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis. PLoS ONE 2009, 4(1):e4186.
    • (2009) PLoS ONE , vol.4 , Issue.1
    • Wieten, L.1    Berlo, S.E.2    Ten Brink, C.B.3    van Kooten, P.J.4    Singh, M.5    van der Zee, R.6
  • 135
    • 0025770202 scopus 로고
    • A synthetic mycobacterial heat shock peptide prevents adjuvant arthritis but not proteoglycan-induced synovitis in the rat
    • Golden H.W., Maniglia C.A., Ranges G.E. A synthetic mycobacterial heat shock peptide prevents adjuvant arthritis but not proteoglycan-induced synovitis in the rat. Agents Actions 1991, 34(1-2):148-150.
    • (1991) Agents Actions , vol.34 , Issue.1-2 , pp. 148-150
    • Golden, H.W.1    Maniglia, C.A.2    Ranges, G.E.3
  • 136
    • 0027759392 scopus 로고
    • Relationship between collagen-induced and adjuvant arthritis in the Lewis rat
    • Hunt D.W., Corson L., Barker H.D., Levy J.G., Petty R.E. Relationship between collagen-induced and adjuvant arthritis in the Lewis rat. J Autoimmun 1993, 6(6):691-700.
    • (1993) J Autoimmun , vol.6 , Issue.6 , pp. 691-700
    • Hunt, D.W.1    Corson, L.2    Barker, H.D.3    Levy, J.G.4    Petty, R.E.5
  • 137
    • 0033011322 scopus 로고    scopus 로고
    • Overexpression of human homologs of the bacterial DnaJ chaperone in the synovial tissue of patients with rheumatoid arthritis
    • Kurzik-Dumke U., Schick C., Rzepka R., Melchers I. Overexpression of human homologs of the bacterial DnaJ chaperone in the synovial tissue of patients with rheumatoid arthritis. Arthritis Rheum 1999, 42(2):210-220.
    • (1999) Arthritis Rheum , vol.42 , Issue.2 , pp. 210-220
    • Kurzik-Dumke, U.1    Schick, C.2    Rzepka, R.3    Melchers, I.4
  • 139
    • 0029432651 scopus 로고
    • Analysis of human 65 kD heat shock protein mRNA using polymerase chain reaction in synovia of rheumatoid arthritis patients
    • Kodama E., Kasukawa R., Miyata M., Shigeta S., Ito M. Analysis of human 65 kD heat shock protein mRNA using polymerase chain reaction in synovia of rheumatoid arthritis patients. Fukushima J Med Sci 1995, 41(2):95-102.
    • (1995) Fukushima J Med Sci , vol.41 , Issue.2 , pp. 95-102
    • Kodama, E.1    Kasukawa, R.2    Miyata, M.3    Shigeta, S.4    Ito, M.5
  • 140
    • 0027052203 scopus 로고
    • The development of monoclonal antibodies to the human mitochondrial 60-kd heat-shock protein, and their use in studying the expression of the protein in rheumatoid arthritis
    • Sharif M., Worrall J.G., Singh B., Gupta R.S., Lydyard P.M., Lambert C., et al. The development of monoclonal antibodies to the human mitochondrial 60-kd heat-shock protein, and their use in studying the expression of the protein in rheumatoid arthritis. Arthritis Rheum 1992, 35(12):1427-1433.
    • (1992) Arthritis Rheum , vol.35 , Issue.12 , pp. 1427-1433
    • Sharif, M.1    Worrall, J.G.2    Singh, B.3    Gupta, R.S.4    Lydyard, P.M.5    Lambert, C.6
  • 141
    • 0025210457 scopus 로고
    • Presence of human 65 kD heat shock protein (hsp) in inflamed joints and subcutaneous nodules of RA patients
    • Karlsson-Parra A., Soderstrom K., Ferm M., Ivanyi J., Kiessling R., Klareskog L. Presence of human 65 kD heat shock protein (hsp) in inflamed joints and subcutaneous nodules of RA patients. Scand J Immunol 1990, 31(6):283-288.
    • (1990) Scand J Immunol , vol.31 , Issue.6 , pp. 283-288
    • Karlsson-Parra, A.1    Soderstrom, K.2    Ferm, M.3    Ivanyi, J.4    Kiessling, R.5    Klareskog, L.6
  • 142
    • 0025225388 scopus 로고
    • Antibodies to the mycobacterial 65-kd heat-shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis
    • de Graeff-Meeder E.R., Voorhorst M., van Eden W., Schuurman H.J., Huber J., Barkley D., et al. Antibodies to the mycobacterial 65-kd heat-shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis. Am J Pathol 1990, 137(5):1013-1017.
    • (1990) Am J Pathol , vol.137 , Issue.5 , pp. 1013-1017
    • de Graeff-Meeder, E.R.1    Voorhorst, M.2    van Eden, W.3    Schuurman, H.J.4    Huber, J.5    Barkley, D.6
  • 143
    • 0344585492 scopus 로고    scopus 로고
    • Aberrant extracellular and dendritic cell (DC) surface expression of heat shock protein (hsp)70 in the rheumatoid joint: possible mechanisms of hsp/DC-mediated cross-priming
    • Martin C.A., Carsons S.E., Kowalewski R., Bernstein D., Valentino M., Santiago-Schwarz F. Aberrant extracellular and dendritic cell (DC) surface expression of heat shock protein (hsp)70 in the rheumatoid joint: possible mechanisms of hsp/DC-mediated cross-priming. J Immunol 2003, 171(11):5736-5742.
    • (2003) J Immunol , vol.171 , Issue.11 , pp. 5736-5742
    • Martin, C.A.1    Carsons, S.E.2    Kowalewski, R.3    Bernstein, D.4    Valentino, M.5    Santiago-Schwarz, F.6
  • 144
    • 33947593227 scopus 로고    scopus 로고
    • Heat shock protein 70 membrane expression on fibroblast-like synovial cells derived from synovial tissue of patients with rheumatoid and juvenile idiopathic arthritis
    • Nguyen T.T., Gehrmann M., Zlacka D., Sosna A., Vavrincova P., Multhoff G., et al. Heat shock protein 70 membrane expression on fibroblast-like synovial cells derived from synovial tissue of patients with rheumatoid and juvenile idiopathic arthritis. Scand J Rheumatol 2006, 35(6):447-453.
    • (2006) Scand J Rheumatol , vol.35 , Issue.6 , pp. 447-453
    • Nguyen, T.T.1    Gehrmann, M.2    Zlacka, D.3    Sosna, A.4    Vavrincova, P.5    Multhoff, G.6
  • 145
    • 0032528185 scopus 로고    scopus 로고
    • Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs
    • Schett G., Redlich K., Xu Q., Bizan P., Groger M., Tohidast-Akrad M., et al. Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs. J Clin Invest 1998, 102(2):302-311.
    • (1998) J Clin Invest , vol.102 , Issue.2 , pp. 302-311
    • Schett, G.1    Redlich, K.2    Xu, Q.3    Bizan, P.4    Groger, M.5    Tohidast-Akrad, M.6
  • 146
    • 73249149631 scopus 로고    scopus 로고
    • The differential expressions of 78-kDa glucose regulated protein of infiltrating plasma cells in peripheral joints with the histopathological variants of rheumatoid synovitis
    • Dong W., Li X., Feng Y., Fan C., Chen Z., Zhu P. The differential expressions of 78-kDa glucose regulated protein of infiltrating plasma cells in peripheral joints with the histopathological variants of rheumatoid synovitis. Arthritis Res Ther 2009, 11(1):R4.
    • (2009) Arthritis Res Ther , vol.11 , Issue.1
    • Dong, W.1    Li, X.2    Feng, Y.3    Fan, C.4    Chen, Z.5    Zhu, P.6
  • 147
    • 0347088931 scopus 로고    scopus 로고
    • Continuous enhanced expression of Hsc70 but not Hsp70 in rheumatoid arthritis synovial tissue
    • Schick C., Arbogast M., Lowka K., Rzepka R., Melchers I. Continuous enhanced expression of Hsc70 but not Hsp70 in rheumatoid arthritis synovial tissue. Arthritis Rheum 2004, 50(1):88-93.
    • (2004) Arthritis Rheum , vol.50 , Issue.1 , pp. 88-93
    • Schick, C.1    Arbogast, M.2    Lowka, K.3    Rzepka, R.4    Melchers, I.5
  • 148
    • 0030461023 scopus 로고    scopus 로고
    • Expression of heat shock protein on lymphocytes in peripheral blood and synovial fluid from patients with rheumatoid arthritis
    • Sato H., Miyata M., Kasukawa R. Expression of heat shock protein on lymphocytes in peripheral blood and synovial fluid from patients with rheumatoid arthritis. J Rheumatol 1996, 23(12):2027-2032.
    • (1996) J Rheumatol , vol.23 , Issue.12 , pp. 2027-2032
    • Sato, H.1    Miyata, M.2    Kasukawa, R.3
  • 149
    • 0028670112 scopus 로고
    • Effect of sulphasalazine on gastrointestinal microflora and on mucosal heat shock protein expression in patients with rheumatoid arthritis
    • Kanerud L., Scheynius A., Nord C.E., Hafstrom I. Effect of sulphasalazine on gastrointestinal microflora and on mucosal heat shock protein expression in patients with rheumatoid arthritis. Br J Rheumatol 1994, 33(11):1039-1048.
    • (1994) Br J Rheumatol , vol.33 , Issue.11 , pp. 1039-1048
    • Kanerud, L.1    Scheynius, A.2    Nord, C.E.3    Hafstrom, I.4


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