Interaction between heat-shock protein 73 and HLA-DRB1 alleles associated or not with rheumatoid arthritis

Arthritis and Rheumatism

Volumn 46, Issue 4, 2002, Pages 929-933

  Auger, Isabelle ^a   Lepecuchel, Lydia ^a   Roudier, Jean ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HEAT SHOCK PROTEIN 73; HLA DR1 ANTIGEN; LYSOSOME ENZYME; PROTEIN DNAJ; PROTEIN DNAK;

ARTICLE; DISEASE ASSOCIATION; ESCHERICHIA COLI; HUMAN; LYMPHOBLASTOID CELL; PRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PURIFICATION; RHEUMATOID ARTHRITIS;

EID: 0036222543     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10214     Document Type: Article

References (15)

1. The shared epitope hypothesis: An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
2. Population genetics of rheumatoid arthritis
3. Molecular mimicry reflected through database screening: Serendipity or survival strategy
4. A function for the QKRAA amino acid motif: Mediating binding of dnaJ to dnaK. Implications for the association of rheumatoid arthritis with HLA-DR4
5. Structural features required for the interaction of the Hsp70 molecular chaperone dnaK with its cochaperone dnaJ
6. HLA-DR4 and HLA-DR10 motifs that carry susceptibility to rheumatoid arthritis bind 70 kD heat shock proteins
7. Heat shock proteins, HLA-DR and rheumatoid arthritis
8. The susceptibility sequence to rheumatoid arthritis is cross-reactive B cell epitope shared by the Escherichia coli heat shock protein dnaJ and the histocompatibility leukocyte antigen DRB1*0401 molecule
9. Susceptibility to rheumatoid arthritis maps to a T-cell epitope shared by the HLA-Dw4 DRB1 chain and the Epstein-Barr virus glycoprotein gp110
10. Tolerance to a self-peptide from the third hypervariable region of HLA-DRB1*0401 in rheumatoid arthritis patients and normal subjects
11. Peptide transporter independent stress proteins mediated endosomal processing of endogenous protein antigens for major histocompatibility class I presentation
12. Receptor mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways
13. Polypeptide import and degradation by isolated lysosomes
14. The hsc73 molecular chaperone: Involvement in MHC class II antigen presentation
15. The exchange of one single amino acid at position 71 of the DR4B1 chain leads to significant differences in antigen processing and presentation of a human autoantigen chaperoned by a member of the HSP70 family