Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution

Aging Cell

Volumn 9, Issue 3, 2010, Pages 347-357

  Sun, Liguang ^a   Guo, Jianfei ^a   Brown, Robert ^a   Amagai, Takashi ^b   Zhao, Yong ^c   Su, Dong Ming ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^b MEIJI UNIVERSITY OF INTEGRATIVE MEDICINE   (Japan)

^c INSTITUTE OF ZOOLOGY   (China)

Author keywords

loxP CreERT system; Spontaneous FoxN1 gene recombination; Thymic aging; Thymic epithelium

Indexed keywords

COMPLEMENTARY DNA; UBIQUITIN; FORKHEAD TRANSCRIPTION FACTOR; WHN PROTEIN;

AGED; AGING; ARTICLE; CD4+ T LYMPHOCYTE; CELL FUNCTION; CREER T GENE; EPITHELIUM CELL; FOXN1 GENE; GENE; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION; GENE LOSS; GENETIC RECOMBINATION; INVOLUTION; LOXP SITE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; THYMUS; TRANSGENE; WILD TYPE; ANIMAL; CELL PROLIFERATION; CYTOLOGY; DOWN REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; NUDE MOUSE; ORGAN SIZE; TRANSGENIC MOUSE;

MURINAE; MUS;

AGING; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DOWN-REGULATION; EPITHELIAL CELLS; FORKHEAD TRANSCRIPTION FACTORS; MICE; MICE, NUDE; MICE, TRANSGENIC; ORGAN SIZE; THYMUS GLAND;

EID: 77956688908     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2010.00559.x     Document Type: Article

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