메뉴 건너뛰기




Volumn 158, Issue 7, 1997, Pages 3037-3045

Age-Associated Thymic Atrophy in the Mouse Is Due to a Deficiency Affecting Rearrangement of the TCR during Intrathymic T Cell Development

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; HOMEODOMAIN PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN; RAG 1 PROTEIN; RAG-1 PROTEIN;

EID: 0031111907     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (143)

References (40)
  • 1
    • 0026742510 scopus 로고
    • Cellular determinants of age-related decrements in the T-cell mitogen response of B6CBAF1 mice
    • Flurkey, K., R. A. Miller, and D. E. Harrison. 1992. Cellular determinants of age-related decrements in the T-cell mitogen response of B6CBAF1 mice. J. Gerontol. 47:B115.
    • (1992) J. Gerontol. , vol.47
    • Flurkey, K.1    Miller, R.A.2    Harrison, D.E.3
  • 2
    • 0026580344 scopus 로고
    • Splenic and inguinal lymph node T cells of aged mice respond differently to polyclonal and antigen-specific stimuli
    • Kirschmann, D. A., and D. M. Murasko. 1992. Splenic and inguinal lymph node T cells of aged mice respond differently to polyclonal and antigen-specific stimuli. Cell. Immunol. 139:426.
    • (1992) Cell. Immunol. , vol.139 , pp. 426
    • Kirschmann, D.A.1    Murasko, D.M.2
  • 3
    • 0028349739 scopus 로고
    • Cellular and molecular mechanisms of the IL-12-induced increase in allospecific murine cytolytic T cell activity: Implications for the age-related decline in CTL
    • Bloom, E. T., and J. A. Horvath. 1994. Cellular and molecular mechanisms of the IL-12-induced increase in allospecific murine cytolytic T cell activity: implications for the age-related decline in CTL. J. Immunol. 152:4242.
    • (1994) J. Immunol. , vol.152 , pp. 4242
    • Bloom, E.T.1    Horvath, J.A.2
  • 4
    • 0019060204 scopus 로고
    • The effect of aging on the susceptibility to infection
    • Gardiner, I. 1980. The effect of aging on the susceptibility to infection. Rev. Infect. Dis. 2:801.
    • (1980) Rev. Infect. Dis. , vol.2 , pp. 801
    • Gardiner, I.1
  • 5
    • 0344691608 scopus 로고
    • Effect of sex hormones, nutrition, and aging on the immune response
    • Lange Medical Publications, Los Altos, CA
    • Stites, D. P., J. D. Stobo, H. H. Fudenberg, and J. V. Wells. 1984. Effect of sex hormones, nutrition, and aging on the immune response. In Basic and Clinical Immunology, 5th Ed. Lange Medical Publications, Los Altos, CA, p. 306.
    • (1984) Basic and Clinical Immunology, 5th Ed. , pp. 306
    • Stites, D.P.1    Stobo, J.D.2    Fudenberg, H.H.3    Wells, J.V.4
  • 7
    • 0018833714 scopus 로고
    • Thymus cell migration: Quantitative aspects of cellular traffic from the thymus to the periphery in mice
    • Scollay, R. G., E. C. Butcher, and I. L. Weissman. 1980. Thymus cell migration: quantitative aspects of cellular traffic from the thymus to the periphery in mice. Eur. J. Immunol. 10:210.
    • (1980) Eur. J. Immunol. , vol.10 , pp. 210
    • Scollay, R.G.1    Butcher, E.C.2    Weissman, I.L.3
  • 8
    • 0027056021 scopus 로고
    • Understanding the mechanism of age related decline in immune function
    • Hirokawa, K. 1992. Understanding the mechanism of age related decline in immune function. Nutr. Rev. 50:361.
    • (1992) Nutr. Rev. , vol.50 , pp. 361
    • Hirokawa, K.1
  • 9
    • 0028837645 scopus 로고
    • Reference intervals for human peripheral blood lymphocyte subpopulations from "healthy" young and aged subjects
    • Stulnig, T., C. Maczek, G. Bock, O. Majdic, and G. A. D. Wick. 1995. Reference intervals for human peripheral blood lymphocyte subpopulations from "healthy" young and aged subjects. Int. Arch. Allergy Appl. Immunol. 108:205.
    • (1995) Int. Arch. Allergy Appl. Immunol. , vol.108 , pp. 205
    • Stulnig, T.1    Maczek, C.2    Bock, G.3    Majdic, O.4    Wick, G.A.D.5
  • 11
    • 0027402403 scopus 로고
    • Lymphocyte lifespans: Homeostasis, selection and competition
    • Freitas, A. A., and B. B. Rocha. 1993. Lymphocyte lifespans: homeostasis, selection and competition. Immunol. Today 14 25.
    • (1993) Immunol. Today , vol.14 , pp. 25
    • Freitas, A.A.1    Rocha, B.B.2
  • 13
    • 0028834176 scopus 로고
    • The role of thymus in the aging of Th cell subpopulations and age-associated alteration of cytokine production by these cells
    • Kurashima, C, M. Utsuyama, M. Kasai, S. A. Ishijima, A. Konno, and K. Hirokawa. 1995. The role of thymus in the aging of Th cell subpopulations and age-associated alteration of cytokine production by these cells. Int. Immunol. 7:97.
    • (1995) Int. Immunol. , vol.7 , pp. 97
    • Kurashima, C.1    Utsuyama, M.2    Kasai, M.3    Ishijima, S.A.4    Konno, A.5    Hirokawa, K.6
  • 14
    • 0027177864 scopus 로고
    • + T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression
    • + T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J. Immunol. 151:575.
    • (1993) J. Immunol. , vol.151 , pp. 575
    • Ernst, D.N.1    Weigle, W.O.2    Noonan, D.S.3    McQuitty, D.N.4    Hobbs, M.V.5
  • 16
    • 0026085993 scopus 로고
    • CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus
    • Wu, L., R. Scollay, M. Egerton, M. Pearse, G. J. Spangrude, and K. Shortman. 1991. CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus. Nature 349:71.
    • (1991) Nature , vol.349 , pp. 71
    • Wu, L.1    Scollay, R.2    Egerton, M.3    Pearse, M.4    Spangrude, G.J.5    Shortman, K.6
  • 17
    • 0027153201 scopus 로고
    • - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150:4244.
    • (1993) J. Immunol. , vol.150 , pp. 4244
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 20
    • 0025959244 scopus 로고
    • Surface expression of the beta T cell receptor (TCR) chain in the absence of other TCR or CD3 proteins on immature T cells
    • Kishi, H., P. Borgulya, B. Scott, K. Karjalainen, A. Traunecker, J. Kaufman, and H. von Boehmer. 1991. Surface expression of the beta T cell receptor (TCR) chain in the absence of other TCR or CD3 proteins on immature T cells. EMBO J. 10:93.
    • (1991) EMBO J. , vol.10 , pp. 93
    • Kishi, H.1    Borgulya, P.2    Scott, B.3    Karjalainen, K.4    Traunecker, A.5    Kaufman, J.6    Von Boehmer, H.7
  • 23
    • 0027968305 scopus 로고
    • On a causal mechanism of the thymic involution in man
    • Hartwig, M., and G. Steinmann. 1994. On a causal mechanism of the thymic involution in man. Mech. Ageing Dev. 75:151.
    • (1994) Mech. Ageing Dev. , vol.75 , pp. 151
    • Hartwig, M.1    Steinmann, G.2
  • 24
    • 0017346941 scopus 로고
    • Age related decrease in mouse T cell progenitors
    • Tyan, M. L. 1977. Age related decrease in mouse T cell progenitors. J. Immunol. 118:846.
    • (1977) J. Immunol. , vol.118 , pp. 846
    • Tyan, M.L.1
  • 25
    • 0017079056 scopus 로고
    • Haemopoietic thymocyte precursors. I. Assay and kinetics of the appearance of progeny
    • Kadish, J. L., and R. S. Basch. 1976. Haemopoietic thymocyte precursors. I. Assay and kinetics of the appearance of progeny. J. Exp. Med. 143:1082.
    • (1976) J. Exp. Med. , vol.143 , pp. 1082
    • Kadish, J.L.1    Basch, R.S.2
  • 26
    • 0022585737 scopus 로고
    • Changes in the human thymus during ageing
    • Steinmann, G. G. 1986. Changes in the human thymus during ageing. Curr. Top. Pathol. 75:43.
    • (1986) Curr. Top. Pathol. , vol.75 , pp. 43
    • Steinmann, G.G.1
  • 29
    • 0022451971 scopus 로고
    • Reappearance of the thymus in old rats after orchidectomy: Inhibition of regression by testosterone
    • Greenstein, B. D., F. T. A. Fitzpatrick, I. M. Adcock, M. D. Kendall, and M. J. Wheeler. 1986. Reappearance of the thymus in old rats after orchidectomy: inhibition of regression by testosterone. J. Endocrinol. 110:417.
    • (1986) J. Endocrinol. , vol.110 , pp. 417
    • Greenstein, B.D.1    Fitzpatrick, F.T.A.2    Adcock, I.M.3    Kendall, M.D.4    Wheeler, M.J.5
  • 33
    • 0022529559 scopus 로고
    • In vivo thymocyte maturation: BUdR labeling of cycling thymocytes and phenotypic analysis of their progeny support the single lineage model
    • Penit, C. 1986. In vivo thymocyte maturation: BUdR labeling of cycling thymocytes and phenotypic analysis of their progeny support the single lineage model. J. Immunol. 137:2115.
    • (1986) J. Immunol. , vol.137 , pp. 2115
    • Penit, C.1
  • 34
    • 0029148822 scopus 로고
    • The pattern of T lymphocyte differentiation is altered during thymic involution
    • Thomam, M. L. 1995. The pattern of T lymphocyte differentiation is altered during thymic involution. Mech. Ageing Dev. 82:155.
    • (1995) Mech. Ageing Dev. , vol.82 , pp. 155
    • Thomam, M.L.1
  • 35
    • 0027711831 scopus 로고
    • Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen
    • Mamalaki, C., J. Elliot, T. Norton, N. Yannoutsos, A. R. Townsend, P. Chandler, E. Simpson, and D. Kioussis. 1993. Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen. Dev. Immunol. 3:159.
    • (1993) Dev. Immunol. , vol.3 , pp. 159
    • Mamalaki, C.1    Elliot, J.2    Norton, T.3    Yannoutsos, N.4    Townsend, A.R.5    Chandler, P.6    Simpson, E.7    Kioussis, D.8
  • 36
    • 0027993561 scopus 로고
    • Does age related change in the CD44 defined T cell subsets have functional significance for cytotoxic T cell generation?
    • Bloom, E. T., H. S. Mostowski, and J. A. Horvath. 1994. Does age related change in the CD44 defined T cell subsets have functional significance for cytotoxic T cell generation? Immunol. Lett. 40:251.
    • (1994) Immunol. Lett. , vol.40 , pp. 251
    • Bloom, E.T.1    Mostowski, H.S.2    Horvath, J.A.3
  • 37
    • 0027461784 scopus 로고
    • The life span of naive α/β T cells in secondary lymphoid organs
    • von Boehmer, H., and K. Harfen. 1993. The life span of naive α/β T cells in secondary lymphoid organs. J. Exp. Med. 177:891.
    • (1993) J. Exp. Med. , vol.177 , pp. 891
    • Von Boehmer, H.1    Harfen, K.2
  • 38
    • 0027199434 scopus 로고
    • Interleukin-7: A cofactor for V(D)J rearrangement of the T cell receptor beta gene
    • Muegge, K., M. P. Vila, and S. K. Durum. 1993. Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene. Science 261:93.
    • (1993) Science , vol.261 , pp. 93
    • Muegge, K.1    Vila, M.P.2    Durum, S.K.3
  • 39
    • 0029994684 scopus 로고    scopus 로고
    • IL-7 supports D-J but not V-DJ rearrangement of the TCR-β gene in fetal liver progenitor cells
    • Tsuda, S., S. Rieke, Y. Hashimoto, H. Nakauchi, and Y. Takahama. 1996. IL-7 supports D-J but not V-DJ rearrangement of the TCR-β gene in fetal liver progenitor cells. J. Immunol. 156:3233.
    • (1996) J. Immunol. , vol.156 , pp. 3233
    • Tsuda, S.1    Rieke, S.2    Hashimoto, Y.3    Nakauchi, H.4    Takahama, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.