ERG changes in albino and pigmented mice after optic nerve transection

Vision Research

Volumn 50, Issue 21, 2010, Pages 2176-2187

  Alarcón Martínez, Luis ^a   Avilés Trigueros, Marcelino ^a   Galindo Romero, Caridad ^a   Valiente Soriano, Javier ^a   Agudo Barriuso, Marta ^c   Villa, Pedro de la ^b   Villegas Pérez, Maria P ^a   Vidal Sanz, Manuel ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

^c HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

Author keywords

Adult albino and pigmented mice; Axotomy; Electroretinogram (ERG); Neuronal degeneration; Optic nerve transection (ONT); Retina; Retinal ganglion cells (RGCs); Scotopic threshold response (STR)

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ELECTRORETINOGRAM; FEMALE; MOUSE; MOUSE STRAIN; NERVE TRANSECTION; NONHUMAN; OPTIC NERVE INJURY; PRIORITY JOURNAL; RETINA GANGLION CELL; VISUAL THRESHOLD;

ALBINISM; ANIMALS; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; MICE; OPTIC NERVE INJURIES; PIGMENTATION; RETINAL GANGLION CELLS; SENSORY THRESHOLDS; TIME FACTORS;

EID: 77956652448     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.visres.2010.08.014     Document Type: Article

References (85)

1. Aguayo A.J., Vidal-Sanz M., Villegas-Pérez M.P., Bray G.M. Growth and connectivity of axotomized retinal neurons in adult rats with optic nerves substituted by PNS grafts linking the eye and the midbrain. Annals of the New York Academy of Sciences 1987, 495:1-9.
2. Agudo M., Pérez-Marín M.C., Lonngren U., Sobrado P., Conesa A., Cánovas I., et al. Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crush. Molecular Vision 2008, 14:1050-1063.
3. Agudo M., Pérez-Marín M.C., Sobrado-Calvo P., Lonngren U., Salinas-Navarro M., Canovas I., et al. Proteins belonging to different branches of the apoptotic cascade are immediately up-regulated in the retina after optic nerve transection or optic nerve crush. Investigative Ophthalmology Visual Science 2009, 50:424-431.
4. Alarcón-Martínez L., Avilés-Trigueros M., De la Villa P., Valiente-Soriano J., Salinas-Navarro M., Sánchez-Migallón Carreras M.C., et al. Short and long term axotomy-induced erg changes in albino and pigmented mice. Investigative Ophthalmology and Visual Science 2010, 51. (E-abstract 5566).
5. Alarcón-Martínez L., De la Villa P., Avilés-Trigueros M., Blanco-Velasco R., Villegas-Pérez M.P., Vidal-Sanz M. Short and long term axotomy-induced ERG changes in albino and pigmented rats. Molecular Vision 2009, 15:2373-2383.
6. Avilés-Trigueros M., Sauvé Y., Lund R.D., Vidal-Sanz M. Selective innervation of retinorecipient brainstem nuclei by retinal ganglion cell axons regenerating through peripheral nerve grafts in adult rats. Journal of Neuroscience 2000, 20:361-374.
7. Ball S.L., Petry H.M. Noninvasive assessment of retinal function in rats using multifocal electroretinography. Investigative Ophthalmology and Visual Science 2000, 41:610-617.
8. Ben-Shlomo G., Bakalash S., Lambrou G.N., Latour E., Dawson W.W., Schwartz M., et al. Pattern electroretinography in a rat model of ocular hypertension: Functional evidence for early detection of inner retinal damage. Experimental Eye Research 2005, 81:340-349.
9. Berkelaar M., Clarke D.B., Wang Y.C., Bray G.M., Aguayo A.J. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. Journal of Neuroscience 1994, 14:4368-4374.
10. Brzezinski J.A., Brown N.L., Tanikawa A., Bush R.A., Sieving P.A., Vitaterna M.H., et al. Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice. Investigative Ophthalmology and Visual Science 2005, 46:2540-2551.
11. Bui B.V., Edmunds B., Cioffi G.A., Fortune B. The gradient of retinal functional changes during acute intraocular pressure elevation. Investigative Ophthalmology and Visual Science 2005, 46:202-213.
12. Bui B.V., Fortune B.J. Ganglion cell contributions to the rat full-field electroretinogram. Physiology 2004, 555(Pt 1):153-173.
13. Carter D.A., Vidal-Sanz M., Aguayo A.J. Long-term preservation of intrinsic neurons after axotomy-induced death of retinal ganglion cells. Society of Neuroscience Abstract 1987, 13:1390.
14. Casson R.J., Chidlow G., Wood J.P., Vidal-Sanz M., Osborne N.N. The effect of retinal ganglion cell injury on light-induced photoreceptor degeneration. Investigative Ophthalmology and Visual Science 2004, 45:685-693.
15. Cheunsuang O., Morris R. Astrocytes in the arcuate nucleus and median eminence that take up a fluorescent dye from the circulation express leptin receptors and neuropeptide Y Y1 receptors. Glia 2005, 52:228-233.
16. Chidlow G., Casson R., Sobrado-Calvo P., Vidal-Sanz M., Osborne N.N. Measurement of retinal injury in the rat after optic nerve transection: An RT-PCR study. Molecular Vision 2005, 11:387-396.
17. Colotto A., Falsini B., Salgarello T., Iarossi G., Galan M.E., Scullica L. Photopic negative response of the human ERG: Losses associated with glaucomatous damage. Investigative Ophthalmology and Visual Science 2000, 41:2205-2211.
18. Cuenca N., Pinilla I., Fernández-Sánchez L., Salinas-Navarro M., Alarcón-Martínez L., Avilés-Trigueros M., et al. Changes in the inner and outer retinal layers after acute increase of the intraocular pressure in adult albino swiss mice. Experimental Eye Research 2010, 9:273-285.
19. Dowling J.E. The Retina. An approachable part of the brain 1987, The Belknap Press of Harvard University Press, Cambridge, Massachusetts, and London, England.
20. Fortune B., Bui B.V., Morrison J.C., Johnson E.C., Dong J., Cepurna W.O., et al. Selective ganglion cell functional loss in rats with experimental glaucoma. Investigative Ophthalmology and Visual Science 2004, 45:1854-1862.
21. Frishman L.J. Origins of the electroretinogram. Principles and practice of clinical electrophysiology of vision 2006, 139-184. Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts and London, England. 2nd ed. J.R. Heckenlively, G.B. Arden (Eds.).
22. Frishman L.J., Reddy M.G., Robson J.G. Effects of background light on the human dark-adapted ERG and psychophysical threshold. Journal of the Optical Society of America A. Optics and Image Science 1996, 13:601-612.
23. Frishman L.J., Shen F.F., Du L., Robson J.G., Harwerth R.S., Smith E.L., et al. The scotopic electroretinogram of macaque after retinal ganglion cell loss from experimental glaucoma. Investigative Ophthalmology and Visual Science 1996, 37:125-141.
24. Frishman L.J., Steinberg R.H. Intraretinal analysis of the threshold dark-adapted ERG of cat retina. Journal of Neurophysiology 1989, 61:1221-1232.
25. Frishman L.J., Steinberg R.H. Light-evoked increases in [K+]o in proximal portion of the dark-adapted cat retina. Journal of Neurophysiology 1989, 61:1233-1243.
26. Fu C.T., Sretavan D. Laser-induced ocular hypertension in albino CD-1 mice. Investigative Ophthalmology and Visual Science 2010, 51:980-990.
27. Galindo-Romero C., Avilés-Trigueros M., Jiménez-López M., Valiente-Soriano F., Nadal-Nicolás F., Rodriguez-Llarena S., et al. Time course of retinal ganglion cell degeneration in adult mice after optic nerve axotomy. Investigative Ophthalmology and Visual Science 2010, 51. (ARVO E-abstract 637).
28. Gargini C., Bisti S., Demontis G.C., Valter K., Stone J., Cervetto L. Electroretinogram changes associated with retinal upregulation of trophic factors: Observations following optic nerve section. Neuroscience 2004, 126:775-783.
29. Gari M., Colotto A., Salgarello A., Fadda A., Di Renzo A., Anselmi G., et al. Photopic negative response from retinal hemifields in glaucoma. Investigative Ophthalmology and Visual Science 2009, 50. (E-abstract 5302).
30. Germain F., Calvo M., De La Villa P. Rabbit retinal ganglion cell survival after optic nerve section and its effect on inner plexiform layer. Experimental Eye Research 2004, 79:95-102.
31. Gómez-Ramírez A.M., Villegas-Pérez M.P., Miralles de Imperial J., Salvador-Silva M., Vidal-Sanz M. Effects of intramuscular injection of botulinum toxin and doxorubicin on the survival of abducens motoneurons. Investigative Ophthalmology and Visual Science 1999, 40:414-424.
32. Grozdanic S.D., Betts D.M., Sakaguchi D.S., Allbaugh R.A., Kwon Y.H., Kardon R.H. Laser-induced mouse model of chronic ocular hypertension. Investigative Ophthalmology and Visual Science 2003, 44:4337-4346.
33. Günhan-Agar E., Kahn D., Chalupa L.M. Segregation of on and off bipolar cell axonal arbors in the absence of retinal ganglion cells. Journal of Neuroscience 2000, 20:306-314.
34. He A., Bui B.V., Vingrys A.J. The rate of functional recovery from acute IOP elevation. Investigative Ophthalmology and Visual Science 2006, 47:4872-4880.
35. Holcombe D.J., Lengefeld N., Gole G.A., Barnett N.L. Selective inner retinal dysfunction precedes ganglion cell loss in a mouse glaucoma model. British Journal of Ophthalmology 2008, 92:683-688.
36. Kielczewski J.L., Pease M.E., Quigley H.A. The effect of experimental glaucoma and optic nerve transection on amacrine cells in the rat retina. Investigative Ophthalmology and Visual Science 2005, 46:3188-3196.
37. Kilic E., Hermann D.M., Isenmann S., Bähr M. Effects of pinealectomy and melatonin on the retrograde degeneration of retinal ganglion cells in a novel model of intraorbital optic nerve transection in mice. Journal of Pineal Research 2002, 32:106-111.
38. Kong Y.X., Crowston J.G., Vingrys A.J., Trounce I.A., Bui V.B. Functional changes in the retina during, after acute intraocular pressure elevation in mice. Investigative Ophthalmology and Visual Science 2009, 50:5732-5740.
39. Korth M., Nguyen N.X., Horn F., Martus P. Scotopic threshold response and scotopic PII in glaucoma. Investigative Ophthalmology and Visual Science 1994, 35:619-625.
40. Li B., Barnes G.E., Holt W.F. The decline of the photopic negative response (PhNR) in the rat after optic nerve transection. Documenta Ophthalmologica 2005, 111:23-31.
41. Li R.S., Tay D.K., Chan H.H., So K.F. Changes of retinal functions following the induction of ocular hypertension in rats using argon laser photocoagulation. Clinical and Experimental Ophthalmology 2006, 34:575-583.
42. Lindqvist N., Lönngren U., Agudo M., Näpänkangas U., Vidal-Sanz M., Hallböök F. Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction. Upsala Journal of Medical Sciences 2010, 115:65-80.
43. Lindqvist N., Peinado-Ramónn P., Vidal-Sanz M., Hallböök F. GDNF, Ret, GFR alpha 1 and 2 in the adult retino-tectal system after optic nerve transection. Experimental Neurology 2004, 187:487-499.
44. Lindqvist N., Vidal-Sanz M., Hallböök F. Single cell RT-PCR analysis of tyrosine kinase receptor expression in adult rat retinal ganglion cells isolated by retinal sandwiching. Brain Research and Brain Research Protocols 2002, 10:75-83.
45. Machida S., Gotoh Y., Toba Y., Ohtaki A., Kaneko M., Kurosaka D. Correlation between photopic negative response and retinal nerve fiber layer thickness and optic disc topography in glaucomatous eyes. Investigative Ophthalmology and Visual Science 2008, 49:2201-2207.
46. Machida S., Raz-Prag D., Fariss R.N., Sieving P.A., Bush R.A. Photopic ERG negative response from amacrine cell signaling in RCS rat retinal degeneration. Investigative Ophthalmology and Visual Science 2008, 49:442-452.
47. McKerracher L., Vidal-Sanz M., Aguayo A.J. Slow transport rates of cytoskeletal proteins change during regeneration of axotomized retinal neurons in adult rats. Journal of Neuroscience 1990, 10:641-648.
48. McKerracher L., Vidal-Sanz M., Essagian C., Aguayo A.J. Selective impairment of slow axonal transport after optic nerve injury in adult rats. Journal of Neuroscience 1990, 10:2834-2841.
49. Mojumder D.K., Sherry D.M., Frishman L.J. Contribution of voltage-gated sodium channels to the b-wave of the mammalian flash electroretinogram. Journal of Physiology 2008, 586:2551-2580.
50. Morrison J.C., Johnson E., Cepurna W.O. Rat models for glaucoma research. Progress in Brain Research 2008, 173:285-301.
51. Moshiri A., Gonzalez E., Tagawa K., Maeda H., Wang M., Frishman L.J., et al. Near complete loss of retinal ganglion cells in the math5/brn3b double knockout elicits severe reductions of other cell types during retinal development. Developmental Biology 2008, 316:214-227.
52. Naarendorp F., Sato Y., Cajdric A., Hubbard N.P. Absolute and relative sensitivity of the scotopic system of rat: Electroretinography and behavior. Visual Neuroscience 2001, 18:641-656.
53. Naarendorp F., Sieving P.A. The scotopic threshold response of the cat ERG is suppressed selectively by GABA and glycine. Vision Research 1991, 31:1-15.
54. Nadal-Nicolás F.M., Jiménez-López M., Sobrado-Calvo P., Nieto-López L., Cánovas-Martínez I., Salinas-Navarro M., et al. Brn3a as a marker of retinal ganglion cells: Qualitative and quantitative time course studies in naive and optic nerve-injured retinas. Investigative Ophthalmology and Visual Science 2009, 50:3860-3868.
55. Parrilla-Reverter G., Agudo M., Nadal-Nicolás F., Alarcón-Martínez L., Jiménez-López M., Salinas-Navarro M., et al. Time-course of the retinal nerve fibre layer degeneration after complete intra-orbital optic nerve transection or crush: A comparative study. Vision Research 2009, 49:2808-2825.
56. Parrilla-Reverter G., Agudo M., Sobrado-Calvo P., Salinas-Navarro M., Villegas-Pérez M.P., Vidal-Sanz M. Effects of different neurotrophic factors on the survival of retinal ganglion cells after a complete intraorbital nerve crush injury: A quantitative in vivo study. Experimental Eye Research 2009, 89:32-41.
57. Peinado-Ramón P., Salvador M., Villegas-Pérez M.P., Vidal-Sanz M. Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study. Investigative Ophthalmology and Visual Science 1996, 37:489-500.
58. Robson J.G., Frishman L.J. Response linearity and kinetics of the cat retina: The bipolar cell component of the dark-adapted electroretinogram. Visual Neuroscience 1995, 12:837-850.
59. Salinas-Navarro M., Alarcón-Martínez L., Valiente-Soriano F.J., Jiménez-López M., Mayor-Torroglosa S., Avilés-Trigueros M., et al. Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration. Experimental Eye Research 2010, 90:168-183.
60. Salinas-Navarro M., Alarcón-Martínez L., Valiente-Soriano F.J., Ortín-Martínez A., Jiménez-López M., Avilés-Trigueros M., et al. Functional and morphological effects of laser-induced ocular hypertension in adult albino swiss mice retina. Molecular Vision 2009, 15:2578-2598.
61. Salinas-Navarro M., Jiménez-López M., Valiente-Soriano F., Alarcón-Martínez L., Avilés-Trigueros M., Mayor-Torroglosa S., et al. Retinal ganglion cell population in adult albino and pigmented mice: A computerised analysis of the entire population and its spatial distribution. Vision Research 2009, 49:636-646.
62. Salinas-Navarro M., Mayor-Torroglosa S., Jiménez-López M., Avilés-Trigueros M., Holmes T.M., Lund R.D., et al. A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats. Vision Research 2009, 49:115-126.
63. Salvador-Silva M., Vidal-Sanz M., Villegas-Pérez M.P. Microglial cells in the retina of Carassius auratus: Effects of optic nerve crush. Journal of Comparative Neurology 2000, 417:431-447.
64. Saszik S., Frishman L.J., Robson J.G. The scotopic threshold response of the dark-adapted electroretinogram of the mouse. Journal of Physiology 2002, 543:899-916.
65. Schlamp C.L., Johnson E.C., Li Y., Morrison J.C., Nickells R.W. Changes in Thy1 gene expression associated with damaged retinal ganglion cells. Molecular Vision 2001, 7:192-201.
66. Schremser J.L., Williams T.P. Photoreceptor plasticity in the albino rat retina following unilateral optic nerve section. Experimental Eye Research 1992, 55:393-399.
67. Sieving P.A. Retinal ganglion cell loss does not abolish the scotopic threshold response (STR) of the cat and human ERG. Clinical Vision Science 1991, 2:149-158.
68. Sieving P.A., Frishman L.J., Steinberg R.H. Scotopic threshold response of proximal retina in cat. Journal of Neurophysiology 1986, 56:1049-1061.
69. Sieving P.A., Nino C. Human scotopic threshold response. Investigative Ophthalmology and Visual Science 1988, 29:1608-1614.
70. Sobrado-Calvo P., Vidal-Sanz M., Villegas-Pérez M.P. Rat retinal microglial cells under normal conditions, after optic nerve section, and after optic nerve section and intravitreal injection of trophic factors or macrophage inhibitory factor. Journal of Comparative Neurology 2007, 501(6):866-878.
71. Vidal-Sanz M., Bray G.M., Aguayo A.J. Regenerated synapses persist in the superior colliculus after the regrowth of retinal ganglion cell axons. Journal of Neurocytology 1991, 20:940-952.
72. Vidal-Sanz M., Bray G.M., Villegas-Perez M.P., Thanos S., Aguayo A.J. Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. Journal of Neuroscience 1987, 7:2894-2909.
73. Vidal-Sanz M., Lafuente M.P., Mayor S., de Imperial J.M., Villegas-Pérez M.P. Retinal ganglion cell death induced by retinal ischemia. Neuroprotective effects of two alpha-2 agonists. Survey of Ophthalmology 2001, 45:261-267.
74. Vidal-Sanz M., Lafuente M., Sobrado-Calvo P., Sellés-Navarro I., Rodríguez E., Mayor-Torroglosa S., et al. Death and neuroprotection of retinal ganglion cells after different types of injury. Neurotoxicity Research 2000, 2:215-227.
75. Vidal-Sanz M., Villegas-Perez M.P., Bray G.M., Aguayo A.J. Persistent retrograde labeling of adult rat retinal ganglion cells with the carbocyanine dye diI. Experimental Neurology 1988, 102:92-101.
76. Vidal-Sanz M., Villegas-Perez M.P., Bray G.M., Aguayo A.J. Use of peripheral nerve grafts to study regeneration after CNS injury. Neuroprotocols 1993, 3:29-33.
77. Villegas-Pérez M.P., Vidal-Sanz M., Bray G.M., Aguayo A.J. Influences of peripheral nerve grafts on the survival and regrowth of axotomized retinal ganglion cells in adult rats. Journal of Neuroscience 1988, 8:265-280.
78. Villegas-Pérez M.P., Vidal-Sanz M., Rasminsky M., Bray G.M., Aguayo A.J. Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats. Journal of Neurobiology 1993, 24:23-36.
79. Viswanathan S., Frishman L.J., Robson J.G., Harwerth R.S., Smith E.L. The photopic negative response of the macaque electroretinogram: Reduction by experimental glaucoma. Investigative Ophthalmology and Visual Science 1999, 40:1124-1136.
80. Viswanathan S., Frishman L.J., Robson J.G., Walters J.W. The photopic negative response of the flash electroretinogram in primary open angle glaucoma. Investigative Ophthalmology and Visual Science 2001, 42:514-522.
81. Wachtmeister L. Oscillatory potentials in the retina: What do they reveal. Progress in Retinal and Eye Research 1998, 17:485-521.
82. Wang S., Villegas-Pérez M.P., Holmes T., Lawrence J.M., Vidal-Sanz M., Hurtado-Montalbán N., et al. Evolving neurovascular relationships in the RCS rat with age. Current Eye Research 2003, 27:183-196.
83. Wang S., Villegas-Pérez M.P., Vidal-Sanz M., Lund R.D. Progressive optic axon dystrophy and vascular changes in rd mice. Investigative Ophthalmology and Visual Science 2000, 41:537-545.
84. Wang R., Xu J., Xie J., Kang Z., Sun X., Chen N., et al. Hyperbaric oxygen preconditioning promotes survival of retinal ganglion cells in a rat model of optic nerve crush. Journal of Neurotrauma 2010, 27:763-770.
85. Whiteley S.J., Sauvé Y., Avilés-Trigueros M., Vidal-Sanz M., Lund R.D. Extent and duration of recovered pupillary light reflex following retinal ganglion cell axon regeneration through peripheral nerve grafts directed to the pretectum in adult rats. Experimental Neurology 1998, 154:560-572.