Contribution of voltage-gated sodium channels to the b-wave of the mammalian flash electroretinogram

Journal of Physiology

Volumn 586, Issue 10, 2008, Pages 2551-2580

  Mojumder, Deb Kumar ^a   Sherry, David M ^a   Frishman, Laura J ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; N METHYL DEXTRO ASPARTIC ACID; TETRODOTOXIN; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B WAVE; CELL FUNCTION; CELL LOSS; CONTROLLED STUDY; DARK ADAPTATION; ELECTRORETINOGRAPHY; EVOKED VISUAL RESPONSE; FUNCTIONAL ASSESSMENT; ILLUMINATION; MAMMAL; NERVE CELL DEGENERATION; NERVE TRANSECTION; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; RAT; RETINA BIPOLAR GANGLION CELL; RETINA CONE; RETINA GANGLION CELL; RETINA NERVE CELL; RETINA ROD; SENSITIVITY ANALYSIS; VISION; VISUAL STIMULATION; ADULT; LIGHT ADAPTATION; MESOPIC VISION; PHOTOPIC VISION;

ANIMALS; ELECTRORETINOGRAPHY; OPTIC NERVE INJURIES; PHOTIC STIMULATION; RATS; RATS, INBRED BN; RETINA; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 43749104236     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2008.150755     Document Type: Article

References (128)

1. Ahmed J, Frishman L & Robson JG (1999). Pharmacological removal of positive and negative STRs is required to isolate bipolar cell responses in the macaque scotopic electroretinogram. Invest Opthalmol Vis Sci 40 (Suppl.), S15.
2. Akula JD, Lyubarsky AL & Naarendorp F (2003). The sensitivity and spectral identity of the cones driving the b-wave of the rat electroretinogram. Vis Neurosci 20, 109-117.
3. Awatramani G, Wang J & Slaughter MM (2001). Amacrine and ganglion cell contributions to the electroretinogram in amphibian retina. Vis Neurosci 18, 147-156.
4. Berntson A & Taylor WR (2000). Response characteristics and receptive field widths of on-bipolar cells in the mouse retina. J Physiol 524, 879-889.
5. Bignami A & Dahl D (1979). The radial glia of Muller in the rat retina and their response to injury. An immunofluorescence study with antibodies to the glial fibrillary acidic (GFA) protein. Exp Eye Res 28, 63-69.
6. Birch DG, Hood DC, Locke KG, Hoffman DR & Tzekov RT (2002). Quantitative electroretinogram measures of phototransduction in cone and rod photoreceptors: Normal aging, progression with disease, and test-retest variability. Arch Ophthalmol 120, 1045-1051.
7. Björklund H, Bignami A & Dahl D (1985). Immunohistochemical demonstration of glial fibrillary acidic protein in normal rat Müller glia and retinal astrocytes. Neurosci Lett 54, 363-368.
8. Bleakman D & Lodge D (1998). Neuropharmacology of AMPA and kainate receptors. Neuropharmol 37, 1187-1204.
9. Boos R, Schneider H & Wässle H (1993). Voltage- and transmitter-gated currents of All-amacrine cells in a slice preparation of the rat retina. J Neurosci 13, 2874-2888.
10. Bui BV & Fortune B (2004). Ganglion cell contributions to the rat full-field electroretinogram. J Physiol 555, 153-173.
11. Bui BV & Fortune B (2006). Origin of electroretinogram amplitude growth during light adaptation in pigmented rats. Vis Neurosci 23, 155-167.
12. Bush RA, Hawks KW & Sieving PA (1995). Preservation of inner retinal responses in the aged Royal College of Surgeons rat. Evidence against glutamate excitotoxicity in photoreceptor degeneration. Invest Ophthalmol Vis Sci 36, 2054-2062.
13. Bush RA & Sieving PA (1994). A proximal retinal component in the primate photopic ERG a-wave. Invest Ophthalmol Vis Sci 35, 635-645.
14. Calaza KC, de Mello FG & Gardino PF (2001). GABA release induced by aspartate-mediated activation of NMDA receptors is modulated by dopamine in a selective subpopulation of amacrine cells. J Neurocytol 30, 181-193.
15. Celio MR, Baier W, Schärer L, Gregersen HJ, de Viragh PA & Norman AW (1990). Monoclonal antibodies directed against the calcium binding protein Calbindin D-28k. Cell Calcium 11, 599-602.
16. Chao TI, Grosche J, Biedermann JB, Francke M, Pannicke T, Reichelt W, Wulst M, Muhle C, Pritz-Hohmeier S, Kuhrt H, Faude W, Drommer W, Kasper M, Buse E & Reichenbach A (1997). Comparative studies on mammalian Müller (retinal glial) cells. J Neurocytol 26, 439-454.
17. Cohen ED (2001). Voltage-gated calcium and sodium currents of starburst amacrine cells in the rabbit retina. Vis Neurosci 18, 799-809.
18. Cohen ED & Miller RF (1994). The role of NMDA and non-NMDA excitatory amino acid receptors in the functional organization of primate retinal ganglion cells. Vis Neurosci 11, 317-332.
19. Dawson WW, Trick GL & Litzkow CA (1979). Improved electrode for electroretinography. Invest Ophthalmol Vis Sci 18, 988-991.
20. Deans MR, Volgyi B, Goodenough DA, Bloomfield SA & Paul DL (2002). Connexin36 is essential for transmission of rod-mediated visual signals in the mammalian retina. Neuron 36, 703-712.
21. Debus E, Weber K & Osborn M (1983). Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and for each of the neurofilament triplet polypeptides. Differentiation 25, 193-203.
22. Devaux JJ & Scherer SS (2005). Altered ion channels in an animal model of Charcot-Marie-Tooth disease type IA. J Neurosci 25, 1470-1480.
23. Dib-Hajj SD, Fjell J, Cummins TR, Zheng Z, Fried K, LaMotte R, Black JA & Waxman SG (1999). Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain 83, 591-600.
24. Dixon RG & Eng LF (1980). Glial fibrillary acidic protein in the retina of the developing albino rat: An immunoperoxidase study of paraffin-embedded tissue. J Comp Neurol 195, 305-321.
25. Dong CJ & Hare WA (2000). Contribution to the kinetics and amplitude of the electroretinogram b-wave by third-order retinal neurons in the rabbit retina. Vision Res 40, 579-589.
26. Dong CJ & Hare WA (2002). GABAc feedback pathway modulates the amplitude and kinetics of ERG b-wave in a mammalian retina in vivo. Vision Res 42, 1081-1087.
27. Dureau P, Bonnel S, Menasche M, Dufier JL & Abitbol M (2001). Quantitative analysis of intravitreal injections in the rat. Curr Eye Res 22, 74-77.
28. Eggers ED & Lukasiewicz PD (2006). GABA A, GABA C and glycine receptor-mediated inhibition differentially affects light-evoked signalling from mouse retinal rod bipolar cells. J Physiol 572, 215-225.
29. Ellias SA & Stevens JK (1980). The dendritic varicosity: A mechanism for electrically isolating the dendrites of cat retinal amacrine cells? Brain Res 196, 365-372.
30. Enz R, Brandstatter JH, Wassle H & Bormann J (1996). Immunocytochemical localization of the GABAc receptor rho subunits in the mammalian retina. J Neurosci 16, 4479-4490.
31. Euler T & Masland RH (2000). Light-evoked responses of bipolar cells in a mammalian retina. J Neurophysiol 83, 1817-1829.
32. Feigenspan A, Gustincich S, Bean BP & Raviola E (1998). Spontaneous activity of solitary dopaminergic cells of the retina. J Neurosci 18, 6776-6789.
33. Friedburg C, Thomas MM & Lamb TD (2001). Time course of the flash response of dark- and light-adapted human rod photoreceptors derived from the electroretinogram. J Physiol 534, 217-242.
34. Frishman LJ (2005). Electrogenesis of the ERG. In Retina, 4th edn, ed. Ryan SJ, pp. 103-113. Elsevier Mosby,
35. Frishman LJ, Reddy MG & Robson JG (1996). Effects of background light on the human dark-adapted ERG and psychophysical threshold. J Opt Soc Am A Opt Image Sci Vis 13, 601-612.
36. Frishman LJ & Sieving PA (1995). Evidence for two sites of adaptation affecting the dark-adapted ERG of cats and primates. Vision Res 35, 435-442.
37. Frumkes TE & Eysteinsson T (1987). Suppressive rod-cone interaction in distal vertebrate retina: Intracellular records from Xenopus and Necturus. J Neurophysiol 57, 1361-1382.
38. Gillette MA & Dacheux RF (1995). GABA- and glycine-activated currents in the rod bipolar cell of the rabbit retina. J Neurophysiol 74, 856-875.
39. Goldberg SH, Frumkes TE & Nygaard RW (1983). Inhibitory influence of unstimulated rods in the human retina: Evidence provided by examining cone flicker. Science 221, 180-182.
40. Green DG & Powers MK (1982). Mechanisms of light adaptation in rat retina. Vision Res 22, 209-216.
41. Guldenagel M, Ammermuller J, Feigenspan A, Teubner B, Degen J, Sohl G, Willecke K & Weiler R (2001). Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36. J Neurosci 21, 6036-6044.
42. Hartveit E (1999). Reciprocal synaptic interactions between rod bipolar cells and amacrine cells in the rat retina. J Neurophysiol 81, 2923-2936.
43. Haverkamp S & Wässle H (2000). Immunocytochemical analysis of the mouse retina. J Comp Neurol 424, 1-23.
44. + current by modulating both entry into and recovery from inactivation. J Neurophysiol 92, 3134-3141.
45. Hood DC & Birch DG (1990). The a-wave of the human electroretinogram and rod receptor function. Invest Ophthalmol Vis Sci 31, 2070-2081.
46. Huber G & Matus A (1984). Immunocytochemical localization of microtubule-associated protein 1 in rat cerebellum using monoclonal antibodies. J Cell Biol 98, 777-781.
47. Hughes A (1979). A schematic eye for the rat. Vision Res 19, 569-588.
48. Ichinose T & Lukasiewicz PD (2007). Ambient light regulates sodium channel activity to dynamically control retinal signaling. J Neurosci 27, 4756-4764.
49. Ichinose T, Shields CR & Luckasiewicz PD (2005). Sodium channels in transient retinal bipolar cells enhance visual responses in ganglion cells. J Neurosci 25, 1856-1865.
50. Jacobs GH, Fenwick JA & Williams GA (2001). Cone-based vision of rats for ultraviolet and visible lights. J Exp Biol 204, 2439-2446.
51. Johnson J, Tian N, Caywood MS, Reimer RJ, Edwards RH & Copenhagen DR (2003). Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamate. J Neurosci 23, 518-529.
52. Kamiya K, Kaneda M, Sugawara T, Mazaki E, Okamura N, Montal M, Makita N, Tanaka M, Fukushima K, Fujiwara T, Inoue Y & Yamakawa K (2004). A nonsense mutation of the sodium channel gene SCN2A in a patient with intractable epilepsy and mental decline. J Neurosci 24, 2690-2698.
53. Kao CY (1966). Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomena. Pharmacol Rev 18, 997-1049.
54. Kapousta-Bruneau NV (2000). Opposite effects of GABA A and GABA C receptor antagonists on the b-wave of ERG recorded from the isolated rat retina. Vision Res 40, 1653-1665.
55. + action potentials in human cone and rod photoreceptors. Invest Ophthalmol Vis Sci 46, 390-397.
56. + action potentials in human photoreceptors. Neuron 30, 451-458.
57. Kaneko A, Pinto LH, Tachibana M (1989). Transient calcium current of retinal bipolar cells of the mouse. J Physiol 410, 613-629.
58. Karschin A & Wässle H (1990). Voltage- and transmitter-gated currents in isolated rod bipolar cells of rat retina. J Neurophysiol 63, 860-876.
59. Kermer P, Klocker N, Weishaupt JH & Bahr M (2001). Transection of the optic nerve in rats: Studying neuronal death and survival in vivo. Brain Res Brain Res Protoc 7, 255-260.
60. Li B, Barnes GE & Holt WF (2005). The decline of the photopic negative response (PhNR) in the rat after optic nerve transection. Doc Ophthalmol 111, 23-31.
61. Lipton SA & Tauck DL (1987). Voltage-dependent conductances of solitary ganglion cells dissociated from the rat retina. J Physiol 385, 361-391.
62. Löhrke S & Hofmann HD (1994). Voltage-gated currents of rabbit A- and B-type horizontal cells in retinal monolayer cultures. Vis Neurosci 11, 369-378.
63. Lyubarsky AL, Falsini B, Pennesi ME, Valentini P & Pugh EN Jr (1999). UV- and midwave-sensitive cone-driven retinal responses of the mouse: A possible phenotype for coexpression of cone photopigments. J Neurosci 19, 442-455.
64. Lyubarsky AL, Lem J, Chen J, Falsini B, Iannaccone A & Pugh EN Jr (2002). Functionally rodless mice: Transgenic models for the investigation of cone function in retinal disease and therapy. Vision Res 42, 401-415.
65. + channels in mammalian retinal bipolar cells. Vis Neurosci 22, 119-133.
66. Machida S, Raz-Prag D, Fariss RN, Sieving PA & Bush RA (2008). Photopic ERG negative response from amacrine cell signaling in RCS rat retinal degeneration. Invest Ophthalmol Vis Sci 49, 442-452.
67. Martin KR, Quigley HA, Zack DJ, Levkovitch-Verbin H, Kielczewski J, Valenta D, Baumrind L, Pease ME, Klein RL & Hauswirth WW (2003). Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model. Invest Ophthalmol Vis Sci 44, 4357-4365.
68. Massey SC & McGuire G (1998). The role of glutamate in retinal circuitry. In Excitatory Amino Acids and Synaptic Transmission, ed. Wheal HV & Thomson AM, pp. 201-221. Academic Press, London.
69. Massey SC & Miller RF (1987). Excitatory amino acid receptors of rod- and cone-driven horizontal cells in the rabbit retina. J Neurophysiol 57, 645-659.
70. Massey SC & Miller RF (1990). N-Methyl-D-aspartate receptors of ganglion cells in rabbit retina. J Neurophysiol 63, 16-30.
71. Maxeiner S, Dedek K, Janssen-Bienhold U, Ammermuller J, Brune H, Kirsch T, Pieper M, Degen J, Kruger O, Willecke K & Weiler R (2005). Deletion of connexin45 in mouse retinal neurons disrupts the rod/cone signaling pathway between AII amacrine and ON cone bipolar cells and leads to impaired visual transmission. J Neurosci 25, 566-576.
72. Miller RF & Dowling JE (1970). Intracellular responses of the Muller (glial) cells of mudpuppy retina: Their relation to b-wave of the electroretinogram. J Neurophysiol 33, 323-341.
73. + currents in human retinal bipolar cells. Invest Ophthalmol Vis Sci 47, E-Abstract 3750.
74. Mojumder DK, Frishman LJ, Otteson DC & Sherry DM (2007). Voltage-gated sodium channel a-subunits Na v 1.1, Na v 1.2, and Na v 1.6 in the distal mammalian retina. Mol Vis 13, 2163-2182.
75. Möller A & Eysteinsson T (2003). Modulation of the components of the rat dark-adapted electroretinogram by the three subtypes of GABA receptors. Vis Neurosci 20, 535-542.
76. Naarendorp F, Sato Y, Cajdric A & Hubbard NP (2001). Absolute and relative sensitivity of the scotopic system of rat: Electroretinography and behavior. Vis Neurosci 18, 641-656.
77. Narahashi T, Moore JW & Scott WR (1964). Tetrodotoxin blockage of sodium conductance increase in lobster giant axons. J Gen Physiol 47, 965-974.
78. Negishi K, Kato S & Teranishi T (1988). Dopamine cells and rod bipolar cells contain protein kinase C-like immunoreactivity in some vertebrate retinas. Neurosci Lett 94, 247-252.
79. Nelson R (1977). Cat cones have rod input: A comparison of the response properties of cones and horizontal cell bodies in the retina of the cat. J Comp Neurol 172, 109-135.
80. Nelson R, von Litzow A, Kolb H & Gouras P (1975). Horizontal cells in cat retina with independent dendritic systems. Science 189, 137-139.
81. Nixon PJ, Bui BV, Armitage JA & Vingrys AJ (2001). The contribution of cone responses to rat electroretinograms. Clin Experiment Ophthalmol 29, 193-196.
82. Nusinowitz S, Hood DC & Birch DG (1995). Rod transduction parameters from the a wave of local receptor populations. J Opt Soc Am A Opt Image Sci Vis 12, 2259-2266.
83. Ohkuma M, Kawai F, Horiguchi M & Miyachi EI (2007). Patch-clamp recording of human retinal photoreceptors and bipolar cells. Photochem Photobiol 83, 317-322.
84. Ostermann C, Dickmann U, Muley T & Mader M (1990). Large-scale purification of choline acetyltransferase and production of highly specific antisera. Eur J Biochem 192, 215-218.
85. + currents in mammalian retinal cone bipolar cells. J Neurophysiol 84, 2564-2571.
86. Pasteels B, Rogers J, Blachier F & Pochet R (1990). Calbindin and calretinin localization in retina from different species. Vis Neurosci 5, 1-16.
87. Paupoo AA, Mahroo OA, Friedburg C & Lamb TD (2000). Human cone photoreceptor responses measured by the electroretinogram a-wave during and after exposure to intense illumination. J Physiol 529, 469-482.
88. Pflug R, Nelson R & Ahnelt PK (1990). Background-induced flicker enhancement in cat retinal horizontal cells. I. Temporal and spectral properties. J Neurophysiol 64, 313-325.
89. Protti DA, Flores-Herr N, Li W, Massey SC & Wässle H (2005). Light signaling in scotopic conditions in the rabbit, mouse and rat retina: A physiological and anatomical study. J Neurophysiol 93, 3479-3488.
90. Rangaswamy NV, Frishman LJ, Dorotheo EU, Schiffman JS, Bahrani HM & Tang RA (2004). Photopic ERGs in patients with optic neuropathies: comparison with primate ERGs after pharmacologic blockade of inner retina. Invest Ophthalmol Vis Sci 45, 3827-3837.
91. Rangaswamy NV, Hood DC & Frishman LJ (2003). Regional variations in local contributions to the primate photopic flash ERG: Revealed using the slow-sequence mfERG. Invest Ophthalmol Vis Sci 44, 3233-3247.
92. Rangaswamy NV, Shirato S, Kaneko M, Digby BI, Robson JG & Frishman LJ (2007). Effects of spectral characteristics of ganzfeld stimuli on the photopic negative response (PhNR) of the ERG. Invest Ophthalmol Vis Sci 48, 4818-4828.
93. Rangaswamy NV, Zhou W, Harwerth RS & Frishman LJ (2006). Effect of experimental glaucoma in primates on oscillatory potentials of the slow-sequence mfERG. Invest Ophthalmol Vis Sci 47, 753-767.
94. Robson JG & Frishman LJ (1995). Response linearity and kinetics of the cat retina: The bipolar cell component of the dark-adapted electroretinogram. Vis Neurosci 12, 837-850.
95. Robson JG & Frishman LJ (1996). Photoreceptor and bipolar-cell contributions to the cat electroretinogram: A kinetic model for the early part of the flash response. J Opt Soc Am A Opt Image Sci Vis 13, 613-622.
96. Robson JG, Maeda H, Saszik SM & Frishman LJ (2004). In vivo studies of signaling in rod pathways of the mouse using the electroretinogram. Vision Res 44, 3253-3268.
97. Robson JG, Saszik SM, Ahmed J & Frishman LJ (2003). Rod and cone contributions to the a-wave of the electroretinogram of the macaque. J Physiol 547, 509-530.
98. Roska B, Nemeth E & Werblin FS (1998). Response to change is facilitated by a three-neuron disinhibitory pathway in the tiger salamander retina. J Neurosci 18, 3451-3459.
99. +- current in one type of ON bipolar cell in the ground squirrel retina. Invest Ophthalmol Vis Sci 46, E-Abstract 1122.
100. Saszik SM, Frishman LJ & Paul D. (2002 a). Effect of the rod-driven electroretinogram of eliminating Connexin-36 from the mouse retina. Abstr Soc Neurosci 236.8.
101. Saszik SM, Robson JG & Frishman LJ. (2002b). The scotopic threshold response of the dark-adapted electroretinogram of the mouse. J Physiol 543, 899-916.
102. Schneeweis DM & Schnapf JL (1995). Photovoltage of rods and cones in the macaque retina. Science 268, 1053-1056.
103. Sharma S, Ball SL & Peachey NS (2005). Pharmacological studies of the mouse cone electroretinogram. Vis Neurosci 22, 631-636.
104. Shaw G & Weber K (1983). The structure and development of the rat retina: An immunofluorescence microscopical study using antibodies specific for intermediate filament proteins. Eur J Cell Biol 30, 219-232.
105. Sherry DM, Mitchell R, Standifer KM & du Plessis B (2006). Distribution of plasma membrane-associated syntaxins 1 through 4 indicates distinct trafficking functions in the synaptic layers of the mouse retina. BMC Neurosci 7, 54.
106. Sherry DM, Wang MM, Bates J & Frishman LJ. (2003a). Expression of vesicular glutamate transporter 1 in the mouse retina reveals temporal ordering in development of rod vs. cone and ON vs. OFF circuits. J Comp Neurol 465, 480-498.
107. Sherry DM, Wang MM & Frishman LJ. (2003b). Differential distribution of vesicle associated membrane protein isoforms in the mouse retina. Mol Vis 9, 673-688.
108. Sieving PA, Murayama K & Naarendorp F (1994). Push-pull model of the primate photopic electroretinogram: A role for hyperpolarizing neurons in shaping the b-wave. Vis Neurosci 11, 519-532.
109. Skaliora I, Scobey RP & Chalupa LM (1993). Prenatal development of excitability in cat retinal ganglion cells: Action potentials and sodium currents. J Neurosci 13, 313-323.
110. Smith RG, Freed MA & Sterling P (1986). Microcircuitry of the dark-adapted cat retina: Functional architecture of the rod-cone network. J Neurosci 6, 3505-3517.
111. Soucy E, Wang Y, Nirenberg S, Nathans J & Meister M (1998). A novel signaling pathway from rod photoreceptors to ganglion cells in mammalian retina. Neuron 21, 481-493.
112. Sugiyama K, Gu ZB, Kawase C, Yamamoto T & Kitazawa Y (1999). Optic nerve and peripapillary choroidal microvasculature of the rat eye. Invest Ophthalmol Vis Sci 40, 3084-3090.
113. Thomas MM & Lamb TD (1999). Light adaptation and dark adaptation of human rod photoreceptors measured from the a-wave of the electroretinogram. J Physiol 518, 479-496.
114. Toda K, Bush RA, Humphries P & Sieving PA (1999). The electroretinogram of the rhodopsin knockout mouse. Vis Neurosci 16, 391-398.
115. Tsukamoto Y, Morigiwa K, Ishii M, Takao M, Iwatsuki K, Nakanishi S & Fukuda Y (2007). A novel connection between rods and ON cone bipolar cells revealed by ectopic metabotropic glutamate receptor 7 (mGluR7) in mGluR6-deficient mouse retinas. J Neurosci 27, 6261-6267.
116. Tsukamoto Y, Morigiwa K, Ueda M & Sterling P (2001). Microcircuits for night vision in mouse retina. J Neurosci 21, 8616-8623.
117. Ueda Y, Kaneko A & Kaneda M (1992). Voltage-dependent ionic currents in solitary horizontal cells isolated from cat retina. J Neurophysiol 68, 1143-1150.
118. Viswanathan S, Frishman LJ & Robson JG (2000). The uniform field and pattern ERG in macaques with experimental glaucoma: Removal of spiking activity. Invest Ophthalmol Vis Sci 41, 2797-2810.
119. Viswanathan S, Frishman LJ, Robson JG, Harwerth RS & Smith EL 3rd (1999). The photopic negative response of the macaque electroretinogram: reduction by experimental glaucoma. Invest Ophthalmol Vis Sci 40, 1124-1136.
120. Viswanathan S, Frishman LJ, Robson JG & Walters JW (2001). The photopic negative response of the flash electroretinogram in primary open angle glaucoma. Invest Ophthalmol Vis Sci 42, 514-522.
121. Voigt T (1986). Cholinergic amacrine cells in the rat retina. J Comp Neurol 248, 19-35.
122. Wachtmeister L (1998). Oscillatory potentials in the retina: What do they reveal. Prog Retin Eye Res 17, 485-521.
123. Wang L, el Azazi M, Eklund A & Lillemor W (2001). Background light adaptation of the retinal neuronal adaptive system. I. Effect of background light intensity. Doc Ophthalmol 103, 13-26.
124. Winsky L, Nakata H, Martin BM & Jacobowitz DM (1989). Isolation, partial amino acid sequence, and immunohistochemical localization of a brain-specific calcium-binding protein. Proc Natl Acad Sci U S A 86, 10139-10143.
125. Xiang M, Zhou L, Macke JP, Yoshioka T, Hendry SH, Eddy RL, Shows TB & Nathans J (1995). The Brn-3 family of POU-domain factors: Primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons. J Neurosci 15, 4762-4785.
126. Xu L, Ball SL, Alexander KR & Peachey NS (2003). Pharmacological analysis of the rat cone electroretinogram. Vis Neurosci 20, 297-306.
127. Xu X & Karwoski CJ (1994). Current source density analysis of retinal field potentials. II. Pharmacological analysis of the b-wave and M-wave. J Neurophysiol 72, 96-105.
128. Zenisek D, Henry D, Studholme K, Yazulla S & Matthews G (2001). Voltage-dependent sodium channels are expressed in nonspiking retinal bipolar neurons. J Neurosci 21, 4543-4550.