메뉴 건너뛰기




Volumn 20, Issue 4, 2010, Pages 510-518

Neuronal intrinsic barriers for axon regeneration in the adult CNS

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CARRIER PROTEIN; CILIARY NEUROTROPHIC FACTOR; GLYCOPROTEIN GP 130; INTERLEUKIN 6; JANUS KINASE 2; JNK INTERACTING PROTEIN; KRUPPEL LIKE FACTOR; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAN GUANOSINE TRIPHOSPHATE; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG;

EID: 77956649915     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.conb.2010.03.013     Document Type: Review
Times cited : (164)

References (96)
  • 1
    • 0019856865 scopus 로고
    • Axonal elongation into peripheral nervous system " bridges" after central nervous system injury in adult rats
    • David S., Aguayo A.J. Axonal elongation into peripheral nervous system " bridges" after central nervous system injury in adult rats. Science 1981, 214:931-933.
    • (1981) Science , vol.214 , pp. 931-933
    • David, S.1    Aguayo, A.J.2
  • 2
    • 0029900303 scopus 로고    scopus 로고
    • Degeneration and regeneration of axons in the lesioned spinal cord
    • Schwab M.E., Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol Rev 1996, 76:319-370.
    • (1996) Physiol Rev , vol.76 , pp. 319-370
    • Schwab, M.E.1    Bartholdi, D.2
  • 3
    • 33749002853 scopus 로고    scopus 로고
    • Recapitulate development to promote axonal regeneration: good or bad approach?
    • Filbin M.T. Recapitulate development to promote axonal regeneration: good or bad approach?. Philos Trans R Soc Lond B Biol Sci 2006, 361:1565-1574.
    • (2006) Philos Trans R Soc Lond B Biol Sci , vol.361 , pp. 1565-1574
    • Filbin, M.T.1
  • 4
    • 38649112309 scopus 로고    scopus 로고
    • CNS injury, glial scars, and inflammation: inhibitory extracellular matrices and regeneration failure
    • Fitch M.T., Silver J. CNS injury, glial scars, and inflammation: inhibitory extracellular matrices and regeneration failure. Exp Neurol 2008, 209:294-301.
    • (2008) Exp Neurol , vol.209 , pp. 294-301
    • Fitch, M.T.1    Silver, J.2
  • 5
    • 33746308062 scopus 로고    scopus 로고
    • Glial inhibition of CNS axon regeneration
    • Yiu G., He Z. Glial inhibition of CNS axon regeneration. Nat Rev Neurosci 2006, 7:617-627.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 617-627
    • Yiu, G.1    He, Z.2
  • 6
    • 33746271855 scopus 로고    scopus 로고
    • Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury?
    • Harel N.Y., Strittmatter S.M. Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury?. Nat Rev Neurosci 2006, 7:603-616.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 603-616
    • Harel, N.Y.1    Strittmatter, S.M.2
  • 9
    • 10044238913 scopus 로고    scopus 로고
    • Acute physiological response of mammalian central neurons to axotomy: ionic regulation and electrical activity
    • Mandolesi G., Madeddu F., Bozzi Y., Maffei L., Ratto G.M. Acute physiological response of mammalian central neurons to axotomy: ionic regulation and electrical activity. FASEB J 2004, 18:1934-1936.
    • (2004) FASEB J , vol.18 , pp. 1934-1936
    • Mandolesi, G.1    Madeddu, F.2    Bozzi, Y.3    Maffei, L.4    Ratto, G.M.5
  • 10
    • 0037430098 scopus 로고    scopus 로고
    • Critical calpain-dependent ultrastructural alterations underlie the transformation of an axonal segment into a growth cone after axotomy of cultured Aplysia neurons
    • Spira M.E., Oren R., Dormann A., Gitler D. Critical calpain-dependent ultrastructural alterations underlie the transformation of an axonal segment into a growth cone after axotomy of cultured Aplysia neurons. J Comp Neurol 2003, 457:293-312.
    • (2003) J Comp Neurol , vol.457 , pp. 293-312
    • Spira, M.E.1    Oren, R.2    Dormann, A.3    Gitler, D.4
  • 11
    • 0035568345 scopus 로고    scopus 로고
    • Calcium, protease activation, and cytoskeleton remodeling underlie growth cone formation and neuronal regeneration
    • Spira M.E., Oren R., Dormann A., Ilouz N., Lev S. Calcium, protease activation, and cytoskeleton remodeling underlie growth cone formation and neuronal regeneration. Cell Mol Neurobiol 2001, 21:591-604.
    • (2001) Cell Mol Neurobiol , vol.21 , pp. 591-604
    • Spira, M.E.1    Oren, R.2    Dormann, A.3    Ilouz, N.4    Lev, S.5
  • 12
    • 0030203658 scopus 로고    scopus 로고
    • Priming events and retrograde injury signals. A new perspective on the cellular and molecular biology of nerve regeneration
    • Ambron R.T., Walters E.T. Priming events and retrograde injury signals. A new perspective on the cellular and molecular biology of nerve regeneration. Mol Neurobiol 1996, 13:61-79.
    • (1996) Mol Neurobiol , vol.13 , pp. 61-79
    • Ambron, R.T.1    Walters, E.T.2
  • 14
    • 71149087313 scopus 로고    scopus 로고
    • Taking off the SOCS: cytokine signaling spurs regeneration
    • Newbern J.M., Shoemaker S.E., Snider W.D. Taking off the SOCS: cytokine signaling spurs regeneration. Neuron 2009, 64:591-592.
    • (2009) Neuron , vol.64 , pp. 591-592
    • Newbern, J.M.1    Shoemaker, S.E.2    Snider, W.D.3
  • 18
  • 19
    • 19444385804 scopus 로고    scopus 로고
    • Retrograde axonal transport of JNK signaling molecules influence injury induced nuclear changes in p-c-Jun and ATF3 in adult rat sensory neurons
    • Lindwall C., Kanje M. Retrograde axonal transport of JNK signaling molecules influence injury induced nuclear changes in p-c-Jun and ATF3 in adult rat sensory neurons. Mol Cell Neurosci 2005, 29:269-282.
    • (2005) Mol Cell Neurosci , vol.29 , pp. 269-282
    • Lindwall, C.1    Kanje, M.2
  • 20
    • 14644404885 scopus 로고    scopus 로고
    • Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve
    • Perlson E., Hanz S., Ben-Yaakov K., Segal-Ruder Y., Seger R., Fainzilber M. Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron 2005, 45:715-726.
    • (2005) Neuron , vol.45 , pp. 715-726
    • Perlson, E.1    Hanz, S.2    Ben-Yaakov, K.3    Segal-Ruder, Y.4    Seger, R.5    Fainzilber, M.6
  • 21
    • 66749182241 scopus 로고    scopus 로고
    • Axotomy-induced Smad1 activation promotes axonal growth in adult sensory neurons
    • Zou H., Ho C., Wong K., Tessier-Lavigne M. Axotomy-induced Smad1 activation promotes axonal growth in adult sensory neurons. J Neurosci 2009, 29:7116-7123.
    • (2009) J Neurosci , vol.29 , pp. 7116-7123
    • Zou, H.1    Ho, C.2    Wong, K.3    Tessier-Lavigne, M.4
  • 23
    • 69449105574 scopus 로고    scopus 로고
    • The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration
    • Yan D., Wu Z., Chisholm A.D., Jin Y. The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration. Cell 2009, 138:1005-1018.
    • (2009) Cell , vol.138 , pp. 1005-1018
    • Yan, D.1    Wu, Z.2    Chisholm, A.D.3    Jin, Y.4
  • 24
    • 66349113194 scopus 로고    scopus 로고
    • Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation
    • Hollis E.R., Jamshidi P., Low K., Blesch A., Tuszynski M.H. Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation. Proc Natl Acad Sci USA 2009, 106:7215-7220.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7215-7220
    • Hollis, E.R.1    Jamshidi, P.2    Low, K.3    Blesch, A.4    Tuszynski, M.H.5
  • 25
    • 71149108631 scopus 로고    scopus 로고
    • Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways
    • Lorber B., Howe M.L., Benowitz L.I., Irwin N. Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways. Nat Neurosci 2009, 12:1407-1414.
    • (2009) Nat Neurosci , vol.12 , pp. 1407-1414
    • Lorber, B.1    Howe, M.L.2    Benowitz, L.I.3    Irwin, N.4
  • 26
    • 16244388563 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons in vivo
    • Pernet V., Hauswirth W.W., Polo A.D. Extracellular signal-regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons in vivo. J Neurochem 2005, 93:72-83.
    • (2005) J Neurochem , vol.93 , pp. 72-83
    • Pernet, V.1    Hauswirth, W.W.2    Polo, A.D.3
  • 27
    • 0028003190 scopus 로고
    • Major changes in the expression of the mRNAs for cholinergic differentiation factor/leukemia inhibitory factor and its receptor after injury to adult peripheral nerves and ganglia
    • Banner L.R., Patterson P.H. Major changes in the expression of the mRNAs for cholinergic differentiation factor/leukemia inhibitory factor and its receptor after injury to adult peripheral nerves and ganglia. Proc Natl Acad Sci USA 1994, 91:7109-7113.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7109-7113
    • Banner, L.R.1    Patterson, P.H.2
  • 28
    • 0028153963 scopus 로고
    • Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve
    • Curtis R., Scherer S.S., Somogyi R., Adryan K.M., Ip N.Y., Zhu Y., Lindsay R.M., DiStefano P.S. Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve. Neuron 1994, 12:191-204.
    • (1994) Neuron , vol.12 , pp. 191-204
    • Curtis, R.1    Scherer, S.S.2    Somogyi, R.3    Adryan, K.M.4    Ip, N.Y.5    Zhu, Y.6    Lindsay, R.M.7    DiStefano, P.S.8
  • 29
    • 0029995729 scopus 로고    scopus 로고
    • Leukaemia inhibitory factor induced in the sciatic nerve after axotomy is involved in the induction of galanin in sensory neurons
    • Sun Y., Zigmond R.E. Leukaemia inhibitory factor induced in the sciatic nerve after axotomy is involved in the induction of galanin in sensory neurons. Eur J Neurosci 1996, 8:2213-2220.
    • (1996) Eur J Neurosci , vol.8 , pp. 2213-2220
    • Sun, Y.1    Zigmond, R.E.2
  • 30
    • 0030890718 scopus 로고    scopus 로고
    • Gp130 and the interleukin-6 family of cytokines
    • Taga T., Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Annu Rev Immunol 1997, 15:797-819.
    • (1997) Annu Rev Immunol , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 31
    • 0037148523 scopus 로고    scopus 로고
    • Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult
    • Schweizer U., Gunnersen J., Karch C., Wiese S., Holtmann B., Takeda K., Akira S., Sendtner M. Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult. J Cell Biol 2002, 156:287-297.
    • (2002) J Cell Biol , vol.156 , pp. 287-297
    • Schweizer, U.1    Gunnersen, J.2    Karch, C.3    Wiese, S.4    Holtmann, B.5    Takeda, K.6    Akira, S.7    Sendtner, M.8
  • 32
    • 14044250276 scopus 로고    scopus 로고
    • Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation
    • Qiu J., Cafferty W.B., McMahon S.B., Thompson S.W. Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation. J Neurosci 2005, 25:1645-1653.
    • (2005) J Neurosci , vol.25 , pp. 1645-1653
    • Qiu, J.1    Cafferty, W.B.2    McMahon, S.B.3    Thompson, S.W.4
  • 33
    • 0021220983 scopus 로고
    • Peripheral injury enhances central regeneration of primary sensory neurones
    • Richardson P.M., Issa V.M. Peripheral injury enhances central regeneration of primary sensory neurones. Nature 1984, 309:791-793.
    • (1984) Nature , vol.309 , pp. 791-793
    • Richardson, P.M.1    Issa, V.M.2
  • 34
    • 0033137077 scopus 로고    scopus 로고
    • Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury
    • Neumann S., Woolf C.J. Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron 1999, 23:83-91.
    • (1999) Neuron , vol.23 , pp. 83-91
    • Neumann, S.1    Woolf, C.J.2
  • 35
    • 0035463768 scopus 로고    scopus 로고
    • Different signaling pathways mediate regenerative versus developmental sensory axon growth
    • Liu R.Y., Snider W.D. Different signaling pathways mediate regenerative versus developmental sensory axon growth. J Neurosci 2001, 21:RC164.
    • (2001) J Neurosci , vol.21
    • Liu, R.Y.1    Snider, W.D.2
  • 37
    • 33744997909 scopus 로고    scopus 로고
    • The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth
    • Cao Z., Gao Y., Bryson J.B., Hou J., Chaudhry N., Siddiq M., Martinez J., Spencer T., Carmel J., Hart R.B., et al. The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth. J Neurosci 2006, 26:5565-5573.
    • (2006) J Neurosci , vol.26 , pp. 5565-5573
    • Cao, Z.1    Gao, Y.2    Bryson, J.B.3    Hou, J.4    Chaudhry, N.5    Siddiq, M.6    Martinez, J.7    Spencer, T.8    Carmel, J.9    Hart, R.B.10
  • 39
    • 36749004288 scopus 로고    scopus 로고
    • Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation
    • Muller A., Hauk T.G., Fischer D. Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation. Brain 2007, 130:3308-3320.
    • (2007) Brain , vol.130 , pp. 3308-3320
    • Muller, A.1    Hauk, T.G.2    Fischer, D.3
  • 40
    • 70449640540 scopus 로고    scopus 로고
    • Neuroprotective and axon growth-promoting effects following inflammatory stimulation on mature retinal ganglion cells in mice depend on ciliary neurotrophic factor and leukemia inhibitory factor
    • Leibinger M., Muller A., Andreadaki A., Hauk T.G., Kirsch M., Fischer D. Neuroprotective and axon growth-promoting effects following inflammatory stimulation on mature retinal ganglion cells in mice depend on ciliary neurotrophic factor and leukemia inhibitory factor. J Neurosci 2009, 29:14334-14341.
    • (2009) J Neurosci , vol.29 , pp. 14334-14341
    • Leibinger, M.1    Muller, A.2    Andreadaki, A.3    Hauk, T.G.4    Kirsch, M.5    Fischer, D.6
  • 41
    • 0033753722 scopus 로고    scopus 로고
    • Cataractogenic lens injury prevents traumatic ganglion cell death and promotes axonal regeneration both in vivo and in culture
    • Fischer D., Pavlidis M., Thanos S. Cataractogenic lens injury prevents traumatic ganglion cell death and promotes axonal regeneration both in vivo and in culture. Invest Ophthalmol Vis Sci 2000, 41:3943-3954.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3943-3954
    • Fischer, D.1    Pavlidis, M.2    Thanos, S.3
  • 42
    • 0034659957 scopus 로고    scopus 로고
    • Lens injury stimulates axon regeneration in the mature rat optic nerve
    • Leon S., Yin Y., Nguyen J., Irwin N., Benowitz L.I. Lens injury stimulates axon regeneration in the mature rat optic nerve. J Neurosci 2000, 20:4615-4626.
    • (2000) J Neurosci , vol.20 , pp. 4615-4626
    • Leon, S.1    Yin, Y.2    Nguyen, J.3    Irwin, N.4    Benowitz, L.I.5
  • 44
    • 75749083357 scopus 로고    scopus 로고
    • What are the principal mediators of optic nerve regeneration after inflammatory stimulation in the eye?
    • author reply E9
    • Fischer D. What are the principal mediators of optic nerve regeneration after inflammatory stimulation in the eye?. Proc Natl Acad Sci USA 2010, 107:E8. author reply E9.
    • (2010) Proc Natl Acad Sci USA , vol.107
    • Fischer, D.1
  • 45
    • 72749104890 scopus 로고    scopus 로고
    • Promoting axonal rewiring to improve outcome after stroke
    • Benowitz L.I., Carmichael S.T. Promoting axonal rewiring to improve outcome after stroke. Neurobiol Dis 2010, 37:259-266.
    • (2010) Neurobiol Dis , vol.37 , pp. 259-266
    • Benowitz, L.I.1    Carmichael, S.T.2
  • 46
    • 0006535184 scopus 로고    scopus 로고
    • CNTF, not other trophic factors, promotes axonal regeneration of axotomized retinal ganglion cells in adult hamsters
    • Cui Q., Lu Q., So K.F., Yip H.K. CNTF, not other trophic factors, promotes axonal regeneration of axotomized retinal ganglion cells in adult hamsters. Invest Ophthalmol Vis Sci 1999, 40:760-766.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 760-766
    • Cui, Q.1    Lu, Q.2    So, K.F.3    Yip, H.K.4
  • 47
    • 12244269701 scopus 로고    scopus 로고
    • Intravitreal injections of neurotrophic factors and forskolin enhance survival and axonal regeneration of axotomized beta ganglion cells in cat retina
    • Watanabe M., Tokita Y., Kato M., Fukuda Y. Intravitreal injections of neurotrophic factors and forskolin enhance survival and axonal regeneration of axotomized beta ganglion cells in cat retina. Neuroscience 2003, 116:733-742.
    • (2003) Neuroscience , vol.116 , pp. 733-742
    • Watanabe, M.1    Tokita, Y.2    Kato, M.3    Fukuda, Y.4
  • 48
    • 0037121743 scopus 로고    scopus 로고
    • Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth
    • Lacroix S., Chang L., Rose-John S., Tuszynski M.H. Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth. J Comp Neurol 2002, 454:213-228.
    • (2002) J Comp Neurol , vol.454 , pp. 213-228
    • Lacroix, S.1    Chang, L.2    Rose-John, S.3    Tuszynski, M.H.4
  • 51
    • 52949090018 scopus 로고    scopus 로고
    • SOCS regulation of the JAK/STAT signalling pathway
    • Croker B.A., Kiu H., Nicholson S.E. SOCS regulation of the JAK/STAT signalling pathway. Semin Cell Dev Biol 2008, 19:414-422.
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 414-422
    • Croker, B.A.1    Kiu, H.2    Nicholson, S.E.3
  • 52
    • 0345490835 scopus 로고    scopus 로고
    • Expression of neurotrophin mRNAs in the dorsal root ganglion after spinal nerve injury
    • Shen H., Chung J.M., Chung K. Expression of neurotrophin mRNAs in the dorsal root ganglion after spinal nerve injury. Brain Res Mol Brain Res 1999, 64:186-192.
    • (1999) Brain Res Mol Brain Res , vol.64 , pp. 186-192
    • Shen, H.1    Chung, J.M.2    Chung, K.3
  • 53
    • 0037083631 scopus 로고    scopus 로고
    • Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth
    • Bonilla I.E., Tanabe K., Strittmatter S.M. Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth. J Neurosci 2002, 22:1303-1315.
    • (2002) J Neurosci , vol.22 , pp. 1303-1315
    • Bonilla, I.E.1    Tanabe, K.2    Strittmatter, S.M.3
  • 55
    • 19044374577 scopus 로고    scopus 로고
    • Early changes in gene expression in the dorsal root ganglia after transection of the sciatic nerve; effects of amphiregulin and PAI-1 on regeneration
    • Nilsson A., Moller K., Dahlin L., Lundborg G., Kanje M. Early changes in gene expression in the dorsal root ganglia after transection of the sciatic nerve; effects of amphiregulin and PAI-1 on regeneration. Brain Res Mol Brain Res 2005, 136:65-74.
    • (2005) Brain Res Mol Brain Res , vol.136 , pp. 65-74
    • Nilsson, A.1    Moller, K.2    Dahlin, L.3    Lundborg, G.4    Kanje, M.5
  • 56
    • 0142151019 scopus 로고    scopus 로고
    • Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth
    • Tanabe K., Bonilla I., Winkles J.A., Strittmatter S.M. Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth. J Neurosci 2003, 23:9675-9686.
    • (2003) J Neurosci , vol.23 , pp. 9675-9686
    • Tanabe, K.1    Bonilla, I.2    Winkles, J.A.3    Strittmatter, S.M.4
  • 57
    • 5444270047 scopus 로고    scopus 로고
    • Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation
    • Fischer D., Petkova V., Thanos S., Benowitz L.I. Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation. J Neurosci 2004, 24:8726-8740.
    • (2004) J Neurosci , vol.24 , pp. 8726-8740
    • Fischer, D.1    Petkova, V.2    Thanos, S.3    Benowitz, L.I.4
  • 58
    • 36549068204 scopus 로고    scopus 로고
    • Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration
    • Veldman M.B., Bemben M.A., Thompson R.C., Goldman D. Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration. Dev Biol 2007, 312:596-612.
    • (2007) Dev Biol , vol.312 , pp. 596-612
    • Veldman, M.B.1    Bemben, M.A.2    Thompson, R.C.3    Goldman, D.4
  • 59
    • 0037036144 scopus 로고    scopus 로고
    • Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells
    • Goldberg J.L., Klassen M.P., Hua Y., Barres B.A. Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells. Science 2002, 296:1860-1864.
    • (2002) Science , vol.296 , pp. 1860-1864
    • Goldberg, J.L.1    Klassen, M.P.2    Hua, Y.3    Barres, B.A.4
  • 61
    • 0031264489 scopus 로고    scopus 로고
    • C-Jun expression in adult rat dorsal root ganglion neurons: differential response after central or peripheral axotomy
    • Broude E., McAtee M., Kelley M.S., Bregman B.S. c-Jun expression in adult rat dorsal root ganglion neurons: differential response after central or peripheral axotomy. Exp Neurol 1997, 148:367-377.
    • (1997) Exp Neurol , vol.148 , pp. 367-377
    • Broude, E.1    McAtee, M.2    Kelley, M.S.3    Bregman, B.S.4
  • 63
    • 22144444856 scopus 로고    scopus 로고
    • A transcriptional role for C/EBP beta in the neuronal response to axonal injury
    • Nadeau S., Hein P., Fernandes K.J., Peterson A.C., Miller F.D. A transcriptional role for C/EBP beta in the neuronal response to axonal injury. Mol Cell Neurosci 2005, 29:525-535.
    • (2005) Mol Cell Neurosci , vol.29 , pp. 525-535
    • Nadeau, S.1    Hein, P.2    Fernandes, K.J.3    Peterson, A.C.4    Miller, F.D.5
  • 65
    • 33748681723 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons
    • Miao T., Wu D., Zhang Y., Bo X., Subang M.C., Wang P., Richardson P.M. Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons. J Neurosci 2006, 26:9512-9519.
    • (2006) J Neurosci , vol.26 , pp. 9512-9519
    • Miao, T.1    Wu, D.2    Zhang, Y.3    Bo, X.4    Subang, M.C.5    Wang, P.6    Richardson, P.M.7
  • 66
    • 0033956898 scopus 로고    scopus 로고
    • Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: a novel neuronal marker of nerve injury
    • Tsujino H., Kondo E., Fukuoka T., Dai Y., Tokunaga A., Miki K., Yonenobu K., Ochi T., Noguchi K. Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: a novel neuronal marker of nerve injury. Mol Cell Neurosci 2000, 15:170-182.
    • (2000) Mol Cell Neurosci , vol.15 , pp. 170-182
    • Tsujino, H.1    Kondo, E.2    Fukuoka, T.3    Dai, Y.4    Tokunaga, A.5    Miki, K.6    Yonenobu, K.7    Ochi, T.8    Noguchi, K.9
  • 67
    • 33745001188 scopus 로고    scopus 로고
    • The transcription factor ATF-3 promotes neurite outgrowth
    • Seijffers R., Allchorne A.J., Woolf C.J. The transcription factor ATF-3 promotes neurite outgrowth. Mol Cell Neurosci 2006, 32:143-154.
    • (2006) Mol Cell Neurosci , vol.32 , pp. 143-154
    • Seijffers, R.1    Allchorne, A.J.2    Woolf, C.J.3
  • 68
    • 33750921806 scopus 로고    scopus 로고
    • SRY-box containing gene 11 (Sox11) transcription factor is required for neuron survival and neurite growth
    • Jankowski M.P., Cornuet P.K., McIlwrath S., Koerber H.R., Albers K.M. SRY-box containing gene 11 (Sox11) transcription factor is required for neuron survival and neurite growth. Neuroscience 2006, 143:501-514.
    • (2006) Neuroscience , vol.143 , pp. 501-514
    • Jankowski, M.P.1    Cornuet, P.K.2    McIlwrath, S.3    Koerber, H.R.4    Albers, K.M.5
  • 69
    • 34547484768 scopus 로고    scopus 로고
    • ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration
    • Seijffers R., Mills C.D., Woolf C.J. ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration. J Neurosci 2007, 27:7911-7920.
    • (2007) J Neurosci , vol.27 , pp. 7911-7920
    • Seijffers, R.1    Mills, C.D.2    Woolf, C.J.3
  • 70
    • 71849118200 scopus 로고    scopus 로고
    • NFIL3 and cAMP response element-binding protein form a transcriptional feedforward loop that controls neuronal regeneration-associated gene expression
    • MacGillavry H.D., Stam F.J., Sassen M.M., Kegel L., Hendriks W.T., Verhaagen J., Smit A.B., van Kesteren R.E. NFIL3 and cAMP response element-binding protein form a transcriptional feedforward loop that controls neuronal regeneration-associated gene expression. J Neurosci 2009, 29:15542-15550.
    • (2009) J Neurosci , vol.29 , pp. 15542-15550
    • MacGillavry, H.D.1    Stam, F.J.2    Sassen, M.M.3    Kegel, L.4    Hendriks, W.T.5    Verhaagen, J.6    Smit, A.B.7    van Kesteren, R.E.8
  • 72
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 73
    • 77649269805 scopus 로고    scopus 로고
    • Tuba1a gene expression is regulated by KLF6/7 and is necessary for CNS development and regeneration in zebrafish
    • Veldman M.B., Bemben M.A., Goldman D. Tuba1a gene expression is regulated by KLF6/7 and is necessary for CNS development and regeneration in zebrafish. Mol Cell Neurosci 2010.
    • (2010) Mol Cell Neurosci
    • Veldman, M.B.1    Bemben, M.A.2    Goldman, D.3
  • 74
    • 0034912744 scopus 로고    scopus 로고
    • PTEN and myotubularin: novel phosphoinositide phosphatases
    • Maehama T., Taylor G.S., Dixon J.E. PTEN and myotubularin: novel phosphoinositide phosphatases. Annu Rev Biochem 2001, 70:247-279.
    • (2001) Annu Rev Biochem , vol.70 , pp. 247-279
    • Maehama, T.1    Taylor, G.S.2    Dixon, J.E.3
  • 75
    • 51849084360 scopus 로고    scopus 로고
    • The PTEN-PI3K pathway: of feedbacks and cross-talks
    • Carracedo A., Pandolfi P.P. The PTEN-PI3K pathway: of feedbacks and cross-talks. Oncogene 2008, 27:5527-5541.
    • (2008) Oncogene , vol.27 , pp. 5527-5541
    • Carracedo, A.1    Pandolfi, P.P.2
  • 76
    • 41949101770 scopus 로고    scopus 로고
    • SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs
    • Ma X.M., Yoon S.O., Richardson C.J., Julich K., Blenis J. SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs. Cell 2008, 133:303-313.
    • (2008) Cell , vol.133 , pp. 303-313
    • Ma, X.M.1    Yoon, S.O.2    Richardson, C.J.3    Julich, K.4    Blenis, J.5
  • 77
    • 17644415297 scopus 로고    scopus 로고
    • Cell biology. GSK-3beta and microtubule assembly in axons
    • Zhou F.Q., Snider W.D. Cell biology. GSK-3beta and microtubule assembly in axons. Science 2005, 308:211-214.
    • (2005) Science , vol.308 , pp. 211-214
    • Zhou, F.Q.1    Snider, W.D.2
  • 79
    • 32344443093 scopus 로고    scopus 로고
    • The evolving roles of axonally synthesized proteins in regeneration
    • Willis D.E., Twiss J.L. The evolving roles of axonally synthesized proteins in regeneration. Curr Opin Neurobiol 2006, 16:111-118.
    • (2006) Curr Opin Neurobiol , vol.16 , pp. 111-118
    • Willis, D.E.1    Twiss, J.L.2
  • 80
    • 46549085203 scopus 로고    scopus 로고
    • Function and regulation of local axonal translation
    • Lin A.C., Holt C.E. Function and regulation of local axonal translation. Curr Opin Neurobiol 2008, 18:60-68.
    • (2008) Curr Opin Neurobiol , vol.18 , pp. 60-68
    • Lin, A.C.1    Holt, C.E.2
  • 81
    • 77956652435 scopus 로고    scopus 로고
    • The role of local protein synthesis and degradation in axon regeneration
    • Gumy L.F., Tan C.L., Fawcett J.W. The role of local protein synthesis and degradation in axon regeneration. Exp Neurol 2009.
    • (2009) Exp Neurol
    • Gumy, L.F.1    Tan, C.L.2    Fawcett, J.W.3
  • 85
    • 15444362044 scopus 로고    scopus 로고
    • The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway
    • Corradetti M.N., Inoki K., Guan K.L. The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. J Biol Chem 2005, 280:9769-9772.
    • (2005) J Biol Chem , vol.280 , pp. 9769-9772
    • Corradetti, M.N.1    Inoki, K.2    Guan, K.L.3
  • 86
    • 10044276784 scopus 로고    scopus 로고
    • The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila
    • Reiling J.H., Hafen E. The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes Dev 2004, 18:2879-2892.
    • (2004) Genes Dev , vol.18 , pp. 2879-2892
    • Reiling, J.H.1    Hafen, E.2
  • 87
    • 48449101433 scopus 로고    scopus 로고
    • P53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
    • Budanov A.V., Karin M. p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell 2008, 134:451-460.
    • (2008) Cell , vol.134 , pp. 451-460
    • Budanov, A.V.1    Karin, M.2
  • 88
    • 1142274208 scopus 로고    scopus 로고
    • Cdh1-APC controls axonal growth and patterning in the mammalian brain
    • Konishi Y., Stegmuller J., Matsuda T., Bonni S., Bonni A. Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science 2004, 303:1026-1030.
    • (2004) Science , vol.303 , pp. 1026-1030
    • Konishi, Y.1    Stegmuller, J.2    Matsuda, T.3    Bonni, S.4    Bonni, A.5
  • 91
    • 74949137326 scopus 로고    scopus 로고
    • A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway
    • Ma T.C., Campana A., Lange P.S., Lee H.H., Banerjee K., Bryson J.B., Mahishi L., Alam S., Giger R.J., Barnes S., et al. A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway. J Neurosci 2010, 30:739-748.
    • (2010) J Neurosci , vol.30 , pp. 739-748
    • Ma, T.C.1    Campana, A.2    Lange, P.S.3    Lee, H.H.4    Banerjee, K.5    Bryson, J.B.6    Mahishi, L.7    Alam, S.8    Giger, R.J.9    Barnes, S.10
  • 92
    • 68049147011 scopus 로고    scopus 로고
    • Increased synthesis of spermidine as a result of upregulation of arginase I promotes axonal regeneration in culture and in vivo
    • Deng K., He H., Qiu J., Lorber B., Bryson J.B., Filbin M.T. Increased synthesis of spermidine as a result of upregulation of arginase I promotes axonal regeneration in culture and in vivo. J Neurosci 2009, 29:9545-9552.
    • (2009) J Neurosci , vol.29 , pp. 9545-9552
    • Deng, K.1    He, H.2    Qiu, J.3    Lorber, B.4    Bryson, J.B.5    Filbin, M.T.6
  • 93
    • 69449094846 scopus 로고    scopus 로고
    • Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury
    • Alto L.T., Havton L.A., Conner J.M., Hollis Ii E.R., Blesch A., Tuszynski M.H. Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. Nat Neurosci 2009, 12:1106-1113.
    • (2009) Nat Neurosci , vol.12 , pp. 1106-1113
    • Alto, L.T.1    Havton, L.A.2    Conner, J.M.3    Hollis Ii, E.R.4    Blesch, A.5    Tuszynski, M.H.6
  • 95
    • 70350203996 scopus 로고    scopus 로고
    • Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury
    • Kadoya K., Tsukada S., Lu P., Coppola G., Geschwind D., Filbin M.T., Blesch A., Tuszynski M.H. Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury. Neuron 2009, 64:165-172.
    • (2009) Neuron , vol.64 , pp. 165-172
    • Kadoya, K.1    Tsukada, S.2    Lu, P.3    Coppola, G.4    Geschwind, D.5    Filbin, M.T.6    Blesch, A.7    Tuszynski, M.H.8
  • 96
    • 69449093524 scopus 로고    scopus 로고
    • Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation
    • Garcia-Alias G., Barkhuysen S., Buckle M., Fawcett J.W. Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation. Nat Neurosci 2009, 12:1145-1151.
    • (2009) Nat Neurosci , vol.12 , pp. 1145-1151
    • Garcia-Alias, G.1    Barkhuysen, S.2    Buckle, M.3    Fawcett, J.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.