Axotomy-induced smad1 activation promotes axonal growth in adult sensory neurons

Journal of Neuroscience

Volumn 29, Issue 22, 2009, Pages 7116-7123

  Zou, Hongyan ^a,b   Ho, Carole ^a,b   Wong, Karen ^a   Tessier Lavigne, Marc ^a  

^a GENENTECH INC   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; SMAD1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; EMBRYO; MOUSE; NERVE FIBER; NERVE FIBER GROWTH; NERVE FIBER TRANSECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SENSORY NERVE CELL; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; AXONS; AXOTOMY; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CELLS, CULTURED; ENZYME ACTIVATION; FUNCTIONAL LATERALITY; GANGLIA, SPINAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MICE; MICROARRAY ANALYSIS; RNA, SMALL INTERFERING; SENSORY RECEPTOR CELLS; SMAD1 PROTEIN; TUBULIN;

EID: 66749182241     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5397-08.2009     Document Type: Article

References (28)

1. Bacon A, Kerr NC, Holmes FE, Gaston K, Wynick D (2007) Characterization of an enhancer region of the galanin gene that directs expression to the dorsal root ganglion and confers responsiveness to axotomy. J Neurosci 27:6573-6580. (Pubitemid 46920372)
2. Butler SJ, Dodd J (2003) A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons. Neuron 38:389-401. (Pubitemid 36579142)
3. Cao Z, Gao Y, Bryson JB, Hou J, Chaudhry N, Siddiq M, Martinez J, Spencer T, Carmel J, Hart RB, Filbin MT (2006) The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth. J Neurosci 26:5565-5573. (Pubitemid 44318407)
4. Costigan M, Befort K, Karchewski L, Griffin RS, D'Urso D, Allchorne A, Sitarski J, Mannion JW, Pratt RE, Woolf CJ (2002) Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci 3:16. (Pubitemid 38729131)
5. Eaton BA, Davis GW (2005) LIM Kinase1 controls synaptic stability downstream of the type II BMP receptor. Neuron 47:695-708. (Pubitemid 41208008)
6. Filbin MT (2003) Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat Rev Neurosci 4:703-713. (Pubitemid 37280150)
7. Goldberg JL, Klassen MP, Hua Y, Barres BA (2002) Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells. Science 296:1860-1864. (Pubitemid 34596271)
8. Goldstein LS (2001) Transduction. When worlds collide-trafficking in JNK. Science 291:2102-2103.
9. Hodge LK, Klassen MP, Han BX, Yiu G, Hurrell J, Howell A, Rousseau G, Lemaigre F, Tessier-Lavigne M, Wang F (2007) Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron 55:572-586. (Pubitemid 47241208)
10. Lechleider RJ, Ryan JL, Garrett L, Eng C, Deng C, Wynshaw-Boris A, Roberts AB (2001) Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion. Dev Biol 240:157-167. (Pubitemid 33141115)
11. Lee N, Neitzel KL, Devlin BK, MacLennan AJ (2004) STAT3 phosphorylation in injured axons before sensory and motor neuron nuclei: potential role for STAT3 as a retrograde signaling transcription factor. J Comp Neurol 474:535-545. (Pubitemid 38720423)
12. Lee TH, Seng S, Sekine M, Hinton C, Fu Y, Avraham HK, Avraham S (2007) Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med 4:e186. (Pubitemid 46998627)
13. Lee-Hoeflich ST, Causing CG, Podkowa M, Zhao X, Wrana JL, Attisano L (2004) Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis. EMBO J 23:4792-4801. (Pubitemid 40069709)
14. Makwana M, RaivichG (2005) Molecular mechanisms in successful peripheral regeneration. Febs J 272:2628-2638. (Pubitemid 40825411)
15. Massagué J, Seoane J, Wotton D (2005) Smad transcription factors. Genes Dev 19:2783-2810. (Pubitemid 41739965)
16. McGee AW, Strittmatter SM (2003) The Nogo-66 receptor: focusing myelin inhibition of axon regeneration. Trends Neurosci 26:193-198. (Pubitemid 36412001)
17. Méchaly I, Bourane S, Piquemal D, Al-Jumaily M, Ventéo S, Puech S, Scamps F, Valmier J, Carroll P (2006) Gene profiling during development and after a peripheral nerve traumatism reveals genes specifically induced by injury in dorsal root ganglia. Mol Cell Neurosci 32:217-229. (Pubitemid 44016064)
18. Neumann S, Woolf CJ (1999) Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron 23:83-91. (Pubitemid 29262466)
19. Neumann S, Bradke F, Tessier-Lavigne M, Basbaum AI (2002) Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron 34:885-893. (Pubitemid 34722279)
20. Perlson E, Hanz S, Ben-Yaakov K, Segal-Ruder Y, Seger R, Fainzilber M (2005) Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron 45:715-726. (Pubitemid 40320706)
21. Richardson PM, Issa VM (1984) Peripheral injury enhances central regeneration of primary sensory neurones. Nature 309:791-793. (Pubitemid 14119428)
22. Schwab ME, Bartholdi D (1996) Degeneration and regeneration of axons in the lesioned spinal cord. Physiol Rev 76:319-370. (Pubitemid 26163712)
23. Seijffers R, Mills CD, Woolf CJ (2007) ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration. J Neurosci 27:7911-7920. (Pubitemid 47173306)
24. Skene JH (1989) Axonal growth-associated proteins. Annu Rev Neurosci 12:127-156. (Pubitemid 19085451)
25. Smith DS, Skene JH (1997) A transcription-dependent switch controls competence of adult neurons for distinct modes of axon growth. J Neurosci 17:646-658. (Pubitemid 27024577)
26. Ting CY, Herman T, Yonekura S, Gao S, Wang J, Serpe M, O'Connor MB, Zipursky SL, Lee CH (2007) Tiling of r7 axons in the Drosophila visual system is mediated both by transduction of an activin signal to the nucleus and by mutual repulsion. Neuron 56:793-806.
27. Zhou FQ, Snider WD (2006) Intracellular control of developmental and regenerative axon growth. Philos Trans R Soc Lond B Biol Sci 361:1575-1592. (Pubitemid 44450212)
28. Zhu S, Wang W, Clarke DC, Liu X (2007) Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling. J Biol Chem 282:18327-18338. (Pubitemid 47100257)