Pharmacogenetic influences in obstetric anaesthesia

Best Practice and Research: Clinical Obstetrics and Gynaecology

Volumn 24, Issue 3, 2010, Pages 277-287

  Landau, Ruth ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

blockers; opioid receptor; adrenergic receptor; anaesthesia; analgesia; fentanyl; genomics; opioids; pain; pharmacogenetics; polymorphism; pregnancy; preterm labour; SNP; vasopressors

Indexed keywords

ATENOLOL; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BRONCHODILATING AGENT; CYTOCHROME P450; HEXOPRENALINE; HYPERTENSIVE AGENT; SODIUM CHANNEL NAV1.7; UTERUS SPASMOLYTIC AGENT; VERAPAMIL;

ALLELE; ASTHMA; CARDIOVASCULAR DISEASE; CESAREAN SECTION; DOWN REGULATION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HYPERTENSION; HYPOTENSION; LOSS OF FUNCTION MUTATION; MEDICAL PRACTICE; MORTALITY; NONHUMAN; OBSTETRIC ANALGESIA; OBSTETRIC ANESTHESIA; PHARMACOGENETICS; PHENOTYPE; PREMATURE LABOR; PRIORITY JOURNAL; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SPINAL ANESTHESIA; TOCOLYSIS; FEMALE; METHODOLOGY; PATIENT CARE; PREGNANCY;

ANESTHESIA, OBSTETRICAL; FEMALE; HUMANS; PATIENT CARE MANAGEMENT; PHARMACOGENETICS; POLYMORPHISM, GENETIC; PREGNANCY;

EID: 77956642199     PISSN: 15216934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpobgyn.2009.11.009     Document Type: Review

References (92)

1. W. Kalow, and D.R. Gunn The relation between dose of succinylcholine and duration of apnea in man J Pharmacol Exp Ther 120 1957 203 214
2. P.D. Allen Anesthesia and the human genome project: the quest for accurate prediction of drug responses Anesthesiology 102 2005 494 495
3. J.H. Eisenach, and D.R. Schroeder Genomic discoveries in perioperative medicine: educating the audience Anesthesiology 110 2009 693 695
4. H.F. Galley, A. Mahdy, and D.A. Lowes Pharmacogenetics and anesthesiologists Pharmacogenomics 6 2005 849 856
5. G. Iohom, D. Fitzgerald, and A.J. Cunningham Principles of pharmacogenetics-implications for the anaesthetist Br J Anaesth 93 2004 440 450
6. M. Iravani Anesthesia and pharmacogenetics Am J Ther 16 2009 313 315
7. J.H. Kim, D.A. Schwinn, and R. Landau Pharmacogenomics and perioperative medicine-implications for modern clinical practice Can J Anaesth 55 2008 799 806
8. S.N. Palmer, N.M. Giesecke, and S.C. Body Pharmacogenetics of anesthetic and analgesic agents Anesthesiology 102 2005 663 671
9. R. Searle, and P.M. Hopkins Pharmacogenomic variability and anaesthesia Br J Anaesth 103 2009 14 25
10. D.A. Schwinn, and M. Podgoreanu Pharmacogenomics and end-organ susceptibility to injury in the perioperative period Best Pract Res Clin Anaesthesiol 22 2008 23 37
11. W.D. Ngan Kee, and K.S. Khaw Vasopressors in obstetrics: what should we be using? Curr Opin Anaesthesiol 19 2006 238 243
12. 2-adrenergic receptor N Engl J Med 346 2002 536 538
13. 2-adrenoceptor genotype affects vasopressor requirements during spinal anesthesia for cesarean delivery Anesthesiology 104 2006 644 650
14. A.G. Aya, R. Mangin, and N. Vialles Patients with severe preeclampsia experience less hypotension during spinal anesthesia for elective cesarean delivery than healthy parturients: a prospective cohort comparison Anesth Analg 97 2003 867 872
15. A.G. Aya, N. Vialles, and I. Tanoubi Spinal anesthesia-induced hypotension: a risk comparison between patients with severe preeclampsia and healthy women undergoing preterm cesarean delivery Anesth Analg 101 2005 869 875
16. 2adrenoceptor haplotypes and vasopressor response during spinal anesthesia for cesarean section in preeclampsia ASA Abstract 2009 A860
17. D.W. Cooper, M. Carpenter, and P. Mowbray Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery Anesthesiology 97 2002 1582 1590
18. W.D. Ngan Kee, K.S. Khaw, and P.E. Tan Placental transfer and fetal metabolic effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery Anesthesiology 111 2009 506 512
19. 2-adrenergic receptor genotype and survival among patients receiving beta-blocker therapy after an acute coronary syndrome JAMA 294 2005 1526 1533
20. 1- adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to β-blockade Clin Pharmacol Ther 73 2003 366 371
21. 1-adrenergic receptor polymorphism: a predictor of response to beta-blocker treatment? Clin Pharmacol Ther 74 2003 299 302
22. M.A. Pacanowski, Y. Gong, and R.M. Cooper-Dehoff β-adrenergic receptor gene polymorphisms and β-blocker treatment outcomes in hypertension Clin Pharmacol Ther 84 2008 715 721
23. 1- adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo Pharmacogenetics 11 2001 191 197
24. 1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade Pharmacogenet Genomics 18 2008 895 902
25. S. Cresci, R.J. Kelly, and T.P. Cappola Clinical and genetic modifiers of long-term survival in heart failure J Am Coll Cardiol 54 2009 432 444
26. N.L. Pereira, and R.M. Weinshilboum Cardiovascular pharmacogenomics and individualized drug therapy Nat Rev Cardiol 6 2009 632 638
27. 2-adrenergic receptor polymorphisms with asthma phenotypes J Allergy Clin Immunol 115 2005 963 972
28. 2-adrenergic receptor on albuterol bronchodilator pharmacodynamics Clin Pharmacol Ther 65 1999 519 525
29. E. Israel, V.M. Chinchilli, and J.G. Ford Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial Lancet 364 2004 1505 1512
30. M.E. Wechsler, E. Lehman, and S.C. Lazarus β-Adrenergic receptor polymorphisms and response to salmeterol Am J Respir Crit Care Med 173 2006 519 526
31. J.J. Lima, K.V. Blake, and K.G. Tantisira Pharmacogenetics of asthma Curr Opin Pulm Med 15 2009 57 62
32. 2-Adrenergic receptor genotype and preterm delivery Am J Obstet Gynecol 187 2002 1294 1298
33. 2-adrenergic receptor with preterm labor Int J Gynaecol Obstet 77 2002 209 215
34. 2-adrenergic receptor gene polymorphisms and pregnancy outcome J Perinat Med 32 2004 413 417
35. 2-agonist tocolysis for preterm labor Clin Pharmacol Ther 78 2005 656 663
36. M.S. Esplin, and M.W. Varner Genetic factors in preterm birth-the future BJOG 112 Suppl. 1 2005 97 102
37. R. Romero, J. Espinoza, and W.T. Rogers Proteomic analysis of amniotic fluid to identify women with preterm labor and intra-amniotic inflammation/infection: the use of a novel computational method to analyze mass spectrometric profiling J Matern Fetal Neonatal Med 21 2008 367 388
38. C.S. Buhimschi, V.A. Rosenberg, and A.T. Dulay Multidimensional system biology: genetic markers and proteomic biomarkers of adverse pregnancy outcome in preterm birth Am J Perinatol 25 2008 175 187
39. T. Foulkes, and J.N. Wood Pain genes PLoS Genet 4 2008 e1000086
40. M.L. Lacroix-Fralish, J.B. Ledoux, and J.S. Mogil The Pain genes database: an interactive web browser of pain-related transgenic knockout studies Pain 131 3 2007 e1 e4
41. J.J. Cox, F. Reimann, and A.K. Nicholas An SCN9A channelopathy causes congenital inability to experience pain Nature 444 2006 894 898
42. Y.P. Goldberg, J. MacFarlane, and M.L. MacDonald Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations Clin Genet 71 2007 311 319
43. K.B. Nilsen, A.K. Nicholas, and C.G. Woods Two novel SCN9A mutations causing insensitivity to pain Pain 143 2009 155 158
44. J. de Leon, M.T. Susce, and E. Murray-Carmichael The amplichip cyp450 genotyping test: integrating a new clinical tool Mol Diagn Ther 10 2006 135 151
45. Y. Gasche, Y. Daali, and M. Fathi Codeine intoxication associated with ultrarapid CYP2D6 metabolism N Engl J Med 351 2004 2827 2831
46. G. Koren, J. Cairns, and D. Chitayat Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother Lancet 368 2006 704
47. C.M. Berlin Jr., I.M. Paul, and E.S. Vesell Safety issues of maternal drug therapy during breastfeeding Clin Pharmacol Ther 85 2009 20 22
48. P. Madadi, and G. Koren Pharmacogenetic insights into codeine analgesia: implications to pediatric codeine use Pharmacogenomics 9 2008 1267 1284
49. P. Madadi, C.J. Ross, and M.R. Hayden Pharmacogenetics of neonatal opioid toxicity following maternal use of codeine during breastfeeding: a case-control study Clin Pharmacol Ther 85 2009 31 35
50. S. Willmann, A.N. Edginton, and K. Coboeken Risk to the breast-fed neonate from codeine treatment to the mother: a quantitative mechanistic modeling study Clin Pharmacol Ther 2009
51. C. Ciszkowski, P. Madadi, and M.S. Phillips Codeine, ultrarapid- metabolism genotype, and postoperative death N Engl J Med 361 2009 827 828
52. P. Madadi, G. Koren, and J. Cairns Safety of codeine during breastfeeding: fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine Can Fam Physician 53 2007 33 35
53. U.M. Stamer, and F. Stuber Codeine and tramadol analgesic efficacy and respiratory effects are influenced by CYP2D6 genotype 1294-5; author reply Anaesthesia 62 2007 1295 1296
54. U.M. Stamer, F. Stuber, and T. Muders Respiratory depression with tramadol in a patient with renal impairment and CYP2D6 gene duplication Anesth Analg 107 2008 926 929
55. R. Landau, A. Cahana, and R.M. Smiley Genetic variability of μ-opioid receptor in an obstetric population Anesthesiology 100 2004 1030 1033
56. E.C. Tan, C.H. Tan, and U. Karupathivan μ-opioid receptor gene polymorphisms and heroin dependence in Asian populations Neuroreport 14 2003 569 572
57. C. Bond, K.S. LaForge, and M. Tian Single-nucleotide polymorphism in the human μ-opioid receptor gene alters β-endorphin binding and activity: possible implications for opiate addiction Proc Natl Acad Sci U S A 95 1998 9608 9613
58. R.B. Fillingim, L. Kaplan, and R. Staud The A118G single nucleotide polymorphism of the μ-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans J Pain 6 2005 159 167
59. P. Klepstad, T.T. Rakvag, and S. Kaasa The 118 A > G polymorphism in the human μ-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease Acta Anaesthesiol Scand 48 2004 1232 1239
60. C.C. Reyes-Gibby, S. Shete, and T. Rakvag Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene Pain 130 2007 25 30
61. Y. Ginosar, E.M. Davidson, and Y. Meroz μ-opioid receptor (A118G) single-nucleotide polymorphism affects alfentanil requirements for extracorporeal shock wave lithotripsy: a pharmacokinetic-pharmacodynamic study Br J Anaesth 103 2009 420 427
62. W.Y. Chou, C.H. Wang, and P.H. Liu Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy Anesthesiology 105 2006 334 337
63. W.Y. Chou, L.C. Yang, and H.F. Lu Association of μ-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty Acta Anaesthesiol Scand 50 2006 787 792
64. L. Coulbault, M. Beaussier, and C. Verstuyft Environmental and genetic factors associated with morphine response in the postoperative period Clin Pharmacol Ther 79 2006 316 324
65. M. Hayashida, M. Nagashima, and Y. Satoh Analgesic requirements after major abdominal surgery are associated with OPRM1 gene polymorphism genotype and haplotype Pharmacogenomics 9 2008 1605 1616
66. J. Lotsch Basic genetic statistics are necessary in studies of functional associations in anesthesiology Anesthesiology 107 2007 168 169
67. J. Lotsch, M. Zimmermann, and J. Darimont Does the A118G polymorphism at the μ-opioid receptor gene protect against morphine-6-glucuronide toxicity? Anesthesiology 97 2002 814 819
68. B.G. Oertel, R. Schmidt, and A. Schneider The μ-opioid receptor gene polymorphism 118A > G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers Pharmacogenet Genomics 16 2006 625 636
69. R.R. Romberg, E. Olofsen, and H. Bijl Polymorphism of μ-opioid receptor gene (OPRM1:c.118A > G) does not protect against opioid-induced respiratory depression despite reduced analgesic response Anesthesiology 102 2005 522 530
70. R. Landau, C. Kern, and M.O. Columb Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women Pain 139 1 2008 Sep 30 5 14
71. C. Walter, and J. Lotsch Meta-analysis of the relevance of the OPRM1 118A > G genetic variant for pain treatment Pain 2009
72. C. Wong, R. McCarthy, and J.L. Blouin μ-Opioid receptor genetic polymorphism and the duration of intrathecal fentanyl labor analgesia Abstract SOAP 2007 A26
73. C. Wong, M. Ebarvia, and J. Blouin influence of μ-opioid receptor genetic polymorphism on postoperative intrathecal morphine analgesia ASA Abstract 2008 A620
74. A.T. Sia, Y. Lim, and E.C. Lim A118G single nucleotide polymorphism of human μ-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia Anesthesiology 109 2008 520 526
75. E.C. Tan, E.C. Lim, and Y.Y. Teo Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain Mol Pain 5 2009 32
76. C.S. Nielsen, A. Stubhaug, and D.D. Price Individual differences in pain sensitivity: Genetic and environmental contributions Pain 2007
77. J.K. Zubieta, M.M. Heitzeg, and Y.R. Smith COMT val158met genotype affects μ-opioid neurotransmitter responses to a pain stressor Science 299 2003 1240 1243
78. H. Kim, J.K. Neubert, and A. San Miguel Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament Pain 109 2004 488 496
79. L. Diatchenko, G.D. Slade, and A.G. Nackley Genetic basis for individual variations in pain perception and the development of a chronic pain condition Hum Mol Genet 14 2005 135 143
80. L. Diatchenko, A.G. Nackley, and G.D. Slade Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli Pain 125 2006 216 224
81. P. Flood, J. Evans, and J. Connel-Price polymorphisms in the beta2-adrenergic receptor are associated with a more rapid, less painful labor ASA Abstract 2008 A619
82. H. Kim, D. Clark, and R.A. Dionne Genetic contributions to clinical pain and analgesia: avoiding pitfalls in genetic research J Pain 10 2009 663 693
83. U.M. Stamer, and F. Stuber The pharmacogenetics of analgesia Expert Opin Pharmacother 8 2007 2235 2245
84. B. Kosarac, A.A. Fox, and C.D. Collard Effect of genetic factors on opioid action Curr Opin Anaesthesiol 22 2009 476 482
85. M.L. Lacroix-Fralish, and J.S. Mogil Progress in genetic studies of pain and analgesia Annu Rev Pharmacol Toxicol 49 2009 97 121
86. J.S. Mogil Are we getting anywhere in human pain genetics? Pain 2009
87. H. Kim, E. Ramsay, and H. Lee Genome-wide association study of acute post-surgical pain in humans Pharmacogenomics 10 2009 171 179
88. M. Mata, and D.J. Fink Gene therapy for pain Anesthesiology 106 2007 1079 1080
89. M. Mata, S. Hao, and D.J. Fink Applications of gene therapy to the treatment of chronic pain Curr Gene Ther 8 2008 42 48
90. S.D. Dib-Hajj, A.M. Binshtok, and T.R. Cummins Voltage-gated sodium channels in pain states: role in pathophysiology and targets for treatment Brain Res Rev 60 2009 65 83
91. L. Wang, and R.M. Weinshilboum Pharmacogenomics: candidate gene identification, functional validation and mechanisms Hum Mol Genet 17 2008 R174 R179
92. D.A. Flockhart, T. Skaar, and D.S. Berlin Clinically available pharmacogenomics tests Clin Pharmacol Ther 86 2009 109 113