-
1
-
-
0032522873
-
Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
-
Lazarou J, Pomeranz BH, Corey PN: Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies. JAMA 1998; 279: 1200-5
-
(1998)
JAMA
, vol.279
, pp. 1200-1205
-
-
Lazarou, J.1
Pomeranz, B.H.2
Corey, P.N.3
-
3
-
-
3042568917
-
Pharmacogenetics as related to the practice of cardiothoracic and vascular anesthesia
-
Bukaveckas BL, Valdes R Jr, Linder MW: Pharmacogenetics as related to the practice of cardiothoracic and vascular anesthesia. J Cardiothorac Vasc Anesth 2004; 18: 353-65
-
(2004)
J Cardiothorac Vasc Anesth
, vol.18
, pp. 353-365
-
-
Bukaveckas, B.L.1
Valdes Jr., R.2
Linder, M.W.3
-
4
-
-
4644331966
-
Implications of pharmacogenetics for the practice of anesthesiology
-
Edited by Lake CL, Johnson JO, McLoughlin TM. Philadelphia, Mosby
-
Body SC, Shernan SK: Implications of pharmacogenetics for the practice of anesthesiology, Advances in Anesthesia. Edited by Lake CL, Johnson JO, McLoughlin TM. Philadelphia, Mosby, 2003, pp 269-96
-
(2003)
Advances in Anesthesia
, pp. 269-296
-
-
Body, S.C.1
Shernan, S.K.2
-
5
-
-
4444304722
-
Principles of pharmacogenetics: Implications for the anaesthetist
-
Iohom G, FitzGerald D, Cunningham AJ: Principles of pharmacogenetics: Implications for the anaesthetist. Br J Anaesth 2004; 93:440-50
-
(2004)
Br J Anaesth
, vol.93
, pp. 440-450
-
-
Iohom, G.1
Fitzgerald, D.2
Cunningham, A.J.3
-
6
-
-
0038730698
-
Influence of genotype on perioperative risk and outcome
-
Ziegeler S, Tsusaki BE, Collard CD: Influence of genotype on perioperative risk and outcome. ANESTHESIOLOGY 2003; 99:212-9
-
(2003)
Anesthesiology
, vol.99
, pp. 212-219
-
-
Ziegeler, S.1
Tsusaki, B.E.2
Collard, C.D.3
-
7
-
-
0347526061
-
Human inter-individual DNA sequence variation in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics
-
Hoehe MR, Timmermann B, Lehrach H: Human inter-individual DNA sequence variation in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics. Curr Pharm Biotechnol 2003; 4:351-78
-
(2003)
Curr Pharm Biotechnol
, vol.4
, pp. 351-378
-
-
Hoehe, M.R.1
Timmermann, B.2
Lehrach, H.3
-
8
-
-
0028958140
-
Plasma cholinesterase and abnormal reaction to succinylcholine: Twenty years' experience with the Danish Cholinesterase Research Unit
-
Jensen FS, Viby-Mogensen J: Plasma cholinesterase and abnormal reaction to succinylcholine: Twenty years' experience with the Danish Cholinesterase Research Unit. Acta Anaesthesiol Scand 1995; 39:150-6
-
(1995)
Acta Anaesthesiol Scand
, vol.39
, pp. 150-156
-
-
Jensen, F.S.1
Viby-Mogensen, J.2
-
9
-
-
0028827688
-
Dose-response relationship for mivacurium in patients with phenotypically abnormal plasma cholinesterase activity
-
Ostergaard D, Jensen FS, Skovgaard LT, Viby-Mogensen J: Dose-response relationship for mivacurium in patients with phenotypically abnormal plasma cholinesterase activity. Acta Anaesthesiol Scand 1995; 39:1016-8
-
(1995)
Acta Anaesthesiol Scand
, vol.39
, pp. 1016-1018
-
-
Ostergaard, D.1
Jensen, F.S.2
Skovgaard, L.T.3
Viby-Mogensen, J.4
-
10
-
-
0036150466
-
Screening patients with prolonged neuromuscular blockade after succinylcholine and mi-vacurium
-
Cerf C, Mesguish M, Gabriel I, Amselem S, Duvaldestin P: Screening patients with prolonged neuromuscular blockade after succinylcholine and mi-vacurium. Anesth Analg 2002; 94:461-6
-
(2002)
Anesth Analg
, vol.94
, pp. 461-466
-
-
Cerf, C.1
Mesguish, M.2
Gabriel, I.3
Amselem, S.4
Duvaldestin, P.5
-
11
-
-
0033375477
-
Effect of the gene dosage of CγP2C19 on diazepam metabolism in Chinese subjects
-
Qin XP, Xie HG, Wang W, He N, Huang SL, Xu ZH, Ou-Yang DS, Wang YJ, Zhou HH: Effect of the gene dosage of CγP2C19 on diazepam metabolism in Chinese subjects. Clin Pharmacol Ther 1999; 66:642-6
-
(1999)
Clin Pharmacol Ther
, vol.66
, pp. 642-646
-
-
Qin, X.P.1
Xie, H.G.2
Wang, W.3
He, N.4
Huang, S.L.5
Zh, X.6
Ou-Yang, D.S.7
Wang, Y.J.8
Zhou, H.H.9
-
12
-
-
0034837906
-
Effects of CYP3A4 inhibition by diltiazem on pharmacokinetics and dynamics of diazepam in relation to CYP2C19 genotype status
-
Kosuge K, Jun Y, Watanabe H, Kimura M, Nishimoto M, Ishizaki T, Ohashi K: Effects of CYP3A4 inhibition by diltiazem on pharmacokinetics and dynamics of diazepam in relation to CYP2C19 genotype status. Drug Metab Dispos 2001; 29:1284-9
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1284-1289
-
-
Kosuge, K.1
Jun, Y.2
Watanabe, H.3
Kimura, M.4
Nishimoto, M.5
Ishizaki, T.6
Ohashi, K.7
-
13
-
-
0029028932
-
Geographical/interracial differences in polymorphic drug oxidation: Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19
-
Bertilsson L: Geographical/interracial differences in polymorphic drug oxidation: Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. Clin Pharmacokinet 1995; 29:192-209
-
(1995)
Clin Pharmacokinet
, vol.29
, pp. 192-209
-
-
Bertilsson, L.1
-
14
-
-
0036892578
-
Pharmacokinetics of midazolam and 1'-hydroxymidazolam in Chinese with different CYP3A5 genotypes
-
Shih PS, Huang JD: Pharmacokinetics of midazolam and 1'-hydroxymidazolam in Chinese with different CYP3A5 genotypes. Drug Metab Dispos 2002; 30:1491-6
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1491-1496
-
-
Shih, P.S.1
Huang, J.D.2
-
15
-
-
0036731724
-
Explaining interindividual variability of docetaxel pharmacokineties and pharmacodynamics in Asians through phenotyping and genotyping strategies
-
Gob BC, Lee SC, Wang LZ, Fan L, Guo JY, Lamba J, Schuetz E, Lim R, Lim HL, Ong AB, Lee HS: Explaining interindividual variability of docetaxel pharmacokineties and pharmacodynamics in Asians through phenotyping and genotyping strategies. J Clin Oncol 2002; 20:3683-90
-
(2002)
J Clin Oncol
, vol.20
, pp. 3683-3690
-
-
Gob, B.C.1
Lee, S.C.2
Wang, L.Z.3
Fan, L.4
Guo, J.Y.5
Lamba, J.6
Schuetz, E.7
Lim, R.8
Lim, H.L.9
Ong, A.B.10
Lee, H.S.11
-
16
-
-
0033861614
-
CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4* IB5'-promoter region polymorphism
-
Wandel C, Witte JS, Hall JM, Stein CM. Wood AJ, Wilkinson GR: CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4* IB5'-promoter region polymorphism. Clin Pharmacol Ther 2000; 68:82-91
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 82-91
-
-
Wandel, C.1
Witte, J.S.2
Hall, J.M.3
Stein, C.M.4
Wood, A.J.5
Wilkinson, G.R.6
-
17
-
-
0035487452
-
Genotype-phenotype comparison of the Swiss malignant hyperthermia population
-
Girard T, Urwyler A, Censier K. Mueller CR, Zorzato F. Treves S: Genotype-phenotype comparison of the Swiss malignant hyperthermia population. Hum Mutat 2001; 18:357-8
-
(2001)
Hum Mutat
, vol.18
, pp. 357-358
-
-
Girard, T.1
Urwyler, A.2
Censier, K.3
Mueller, C.R.4
Zorzato, F.5
Treves, S.6
-
18
-
-
0035096493
-
Identification of the Arg1086His mutation in the alpha subunit of the voltage-dependent calcium channel (CACNA1S) in a North American family with malignant hyperthermia
-
Stewart SL, Hogan K, Rosenberg H, Fletcher JE: Identification of the Arg1086His mutation in the alpha subunit of the voltage-dependent calcium channel (CACNA1S) in a North American family with malignant hyperthermia. Clin Genet 2001; 59:178-84
-
(2001)
Clin Genet
, vol.59
, pp. 178-184
-
-
Stewart, S.L.1
Hogan, K.2
Rosenberg, H.3
Fletcher, J.E.4
-
19
-
-
0035147282
-
No pain relief from codeine? An introduction to pharmacogenomics
-
Fagerlund TH, Braaten O: No pain relief from codeine? An introduction to pharmacogenomics. Acta Anaesthesiol Scand 2001; 45:140-9
-
(2001)
Acta Anaesthesiol Scand
, vol.45
, pp. 140-149
-
-
Fagerlund, T.H.1
Braaten, O.2
-
20
-
-
0036323498
-
RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes
-
Robinson RL, Brooks C. Brown SL, Ellis FR, Halsall PJ, Quinnell RJ, Shaw MA, Hopkins PM: RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes. Hum Mutat 2002; 20:88-97
-
(2002)
Hum Mutat
, vol.20
, pp. 88-97
-
-
Robinson, R.L.1
Brooks, C.2
Brown, S.L.3
Ellis, F.R.4
Halsall, P.J.5
Quinnell, R.J.6
Shaw, M.A.7
Hopkins, P.M.8
-
21
-
-
0347354996
-
Multiminicore disease in a family susceptible to malignant hyperthermia: Histology, in vitro contracture tests, and genetic characterization
-
Guis S, Figarella-Branger D, Monnier N, Bendahan D, Kozak-Ribbens G, Mattel JP, Lunardi J, Cozzone PJ, Pellissier JF: Multiminicore disease in a family susceptible to malignant hyperthermia: histology, in vitro contracture tests, and genetic characterization. Arch Neurol 2004; 61:106-13
-
(2004)
Arch Neurol
, vol.61
, pp. 106-113
-
-
Guis, S.1
Figarella-Branger, D.2
Monnier, N.3
Bendahan, D.4
Kozak-Ribbens, G.5
Mattel, J.P.6
Lunardi, J.7
Cozzone, P.J.8
Pellissier, J.F.9
-
22
-
-
0034849743
-
North American malignant hyperthermia population: Screening of the ryanodine receptor gene and identification of novel mutations
-
Sambuughin N, Sei Y, Gallagher KL, Wyre HW, Madsen D, Nelson TE, Fletcher JE, Rosenberg H, Muldoon SM: North American malignant hyperthermia population: Screening of the ryanodine receptor gene and identification of novel mutations. ANESTHESIOLOGY 2001; 95:594-9
-
(2001)
Anesthesiology
, vol.95
, pp. 594-599
-
-
Sambuughin, N.1
Sei, Y.2
Gallagher, K.L.3
Wyre, H.W.4
Madsen, D.5
Nelson, T.E.6
Fletcher, J.E.7
Rosenberg, H.8
Muldoon, S.M.9
-
23
-
-
0033052512
-
Mutation screening of the RYR1 gene and identification of two novel mutations in Italian malignant hyperthermia families
-
Barone V, Massa O, Intravaia E, Bracco A, Di Martino A, Tegazzin V, Cozzolino S, Sorrentino V: Mutation screening of the RYR1 gene and identification of two novel mutations in Italian malignant hyperthermia families. J Med Genet 1999; 36:115-8
-
(1999)
J Med Genet
, vol.36
, pp. 115-118
-
-
Barone, V.1
Massa, O.2
Intravaia, E.3
Bracco, A.4
Di Martino, A.5
Tegazzin, V.6
Cozzolino, S.7
Sorrentino, V.8
-
24
-
-
0036285579
-
Mutation screening in the ryanodine receptor 1 gene (RYR1) in patients susceptible to malignant hyperthermia who show definite IVCT results: Identification of three novel mutations
-
Rueffert H, Olthoff D, Deutlich C, Meinecke CD, Froster UG: Mutation screening in the ryanodine receptor 1 gene (RYR1) in patients susceptible to malignant hyperthermia who show definite IVCT results: identification of three novel mutations. Acta Anaesthesiol Scand 2002; 46:692-8
-
(2002)
Acta Anaesthesiol Scand
, vol.46
, pp. 692-698
-
-
Rueffert, H.1
Olthoff, D.2
Deutlich, C.3
Meinecke, C.D.4
Froster, U.G.5
-
25
-
-
0034871590
-
Homozygous and heterozygous Arg614Cys mutations (1840C->T) in the ryanodine receptor gene co-segregate with malignant hyperthermia susceptibility in a German family
-
Rueffert H, Olthoff D, Deutrich C, Thamm B, Froster UG: Homozygous and heterozygous Arg614Cys mutations (1840C->T) in the ryanodine receptor gene co-segregate with malignant hyperthermia susceptibility in a German family. Br J Anaesth 2001; 87:240-5
-
(2001)
Br J Anaesth
, vol.87
, pp. 240-245
-
-
Rueffert, H.1
Olthoff, D.2
Deutrich, C.3
Thamm, B.4
Froster, U.G.5
-
26
-
-
17344368549
-
Identification of novel mutations in the ryanodine-receptor gene (RYR1) in malignant hyperthermia: Genotype-phenotype correlation
-
Manning BM, Quane KA, Ording H, Urwyler A, Tegazzin V, Lehane M, O'Halloran J, Hartung E, Giblin LM, Lynch PJ, Vaughan P, Censier K, Bendixen D, Comi G, Heytens L, Monsieurs K, Fagerlund T, Wolz W, Heffron JJ, Muller CR, McCarthy TV: Identification of novel mutations in the ryanodine-receptor gene (RYR1) in malignant hyperthermia: genotype-phenotype correlation. Am J Hum Genet 1998; 62:599-609
-
(1998)
Am J Hum Genet
, vol.62
, pp. 599-609
-
-
Manning, B.M.1
Quane, K.A.2
Ording, H.3
Urwyler, A.4
Tegazzin, V.5
Lehane, M.6
O'Halloran, J.7
Hartung, E.8
Giblin, L.M.9
Lynch, P.J.10
Vaughan, P.11
Censier, K.12
Bendixen, D.13
Comi, G.14
Heytens, L.15
Monsieurs, K.16
Fagerlund, T.17
Wolz, W.18
Heffron, J.J.19
Muller, C.R.20
McCarthy, T.V.21
more..
-
27
-
-
0029984604
-
Identification of the enzyme responsible for oxidative halothane metabolism: Implications for prevention of halothane hepatitis
-
Kharasch ED, Hankins D, Mautz D, Thummel KE: Identification of the enzyme responsible for oxidative halothane metabolism: Implications for prevention of halothane hepatitis. Lancet 1996; 347:1367-71
-
(1996)
Lancet
, vol.347
, pp. 1367-1371
-
-
Kharasch, E.D.1
Hankins, D.2
Mautz, D.3
Thummel, K.E.4
-
28
-
-
0032438847
-
Interindividual variability in P450-dependent generation of neoantigens in halothane hepatitis
-
Eliasson E, Gardner I, Hume-Smith H, de W, I, Beaune P, Kenna JG: Interindividual variability in P450-dependent generation of neoantigens in halothane hepatitis. Chem Biol Interact 1998; 116:123-41
-
(1998)
Chem Biol Interact
, vol.116
, pp. 123-141
-
-
Eliasson, E.1
Gardner, I.2
Hume-Smith, H.3
De, W.I.4
Beaune, P.5
Kenna, J.G.6
-
29
-
-
0031005383
-
Genetic predisposition to drug-induced hepatotoxicity
-
Larrey D, Pageaux GP: Genetic predisposition to drug-induced hepatotoxicity. J Hepatol 1997; 26(suppl 2):12-21
-
(1997)
J Hepatol
, vol.26
, Issue.SUPPL. 2
, pp. 12-21
-
-
Larrey, D.1
Pageaux, G.P.2
-
30
-
-
0028997743
-
Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1
-
Ono S, Hatanaka T, Hotta H, Tsutsui M, Satoh T, Gonzalez FJ: Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1. Pharmacogenetics 1995; 5:143-50
-
(1995)
Pharmacogenetics
, vol.5
, pp. 143-150
-
-
Ono, S.1
Hatanaka, T.2
Hotta, H.3
Tsutsui, M.4
Satoh, T.5
Gonzalez, F.J.6
-
31
-
-
0031737607
-
A genetic polymorphism in the regulatory sequences of human CYP2E1: Association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake
-
McCarver DG, Byun R, Mines RN, Hichme M, Wegenek W: A genetic polymorphism in the regulatory sequences of human CYP2E1: Association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake. Toxicol Appl Pharmacol 1998; 152:276-81
-
(1998)
Toxicol Appl Pharmacol
, vol.152
, pp. 276-281
-
-
McCarver, D.G.1
Byun, R.2
Mines, R.N.3
Hichme, M.4
Wegenek, W.5
-
32
-
-
0033048246
-
Genetic and dietary predictors of CYP2E1 activity: A phenotyping study in Hawaii Japanese using chlorzoxazone
-
Marchand LL, Wilkinson GR, Wilkens LR: Genetic and dietary predictors of CYP2E1 activity: A phenotyping study in Hawaii Japanese using chlorzoxazone. Cancer Epidemiol Biomarkers Prev 1999; 8:495-500
-
(1999)
Cancer Epidemiol Biomarkers Prev
, vol.8
, pp. 495-500
-
-
Marchand, L.L.1
Wilkinson, G.R.2
Wilkens, L.R.3
-
34
-
-
0346729786
-
Detection and mapping of quantitative trait loci that determine responsiveness of mice to nitrous oxide antinociception
-
Mueller JL, Ellenberger EA, Vaughn LK, Belknap JK, Quock RM: Detection and mapping of quantitative trait loci that determine responsiveness of mice to nitrous oxide antinociception. Neuroscience 2004; 123:743-9
-
(2004)
Neuroscience
, vol.123
, pp. 743-749
-
-
Mueller, J.L.1
Ellenberger, E.A.2
Vaughn, L.K.3
Belknap, J.K.4
Quock, R.M.5
-
35
-
-
3343022585
-
Mice with a melanocortin 1 receptor mutation have a slightly greater minimum alveolar concentration than control mice
-
Xing Y, Sonner JM, Eger EI, Cascio M, Sessler DI: Mice with a melanocortin 1 receptor mutation have a slightly greater minimum alveolar concentration than control mice. ANESTHESIOLOGY 2004; 101:544-6
-
(2004)
Anesthesiology
, vol.101
, pp. 544-546
-
-
Xing, Y.1
Sonner, J.M.2
Eger, E.I.3
Cascio, M.4
Sessler, D.I.5
-
36
-
-
0033857228
-
Naturally occurring variability in anesthetic potency among inbred mouse strains
-
Sonner JM, Gong D, Eger EI: Naturally occurring variability in anesthetic potency among inbred mouse strains. Anesth Analg 2000; 91:720-6
-
(2000)
Anesth Analg
, vol.91
, pp. 720-726
-
-
Sonner, J.M.1
Gong, D.2
Eger, E.I.3
-
37
-
-
0038462011
-
Adverse effect of nitrous oxide in a child with 5,10- methylenetetrahydrofolate reductase deficiency
-
Selzer RR, Rosenblatt DS, Laxova R, Hogan K: Adverse effect of nitrous oxide in a child with 5,10-methylenetetrahydrofolate reductase deficiency. N Engl J Med 2003; 349:45-50
-
(2003)
N Engl J Med
, vol.349
, pp. 45-50
-
-
Selzer, R.R.1
Rosenblatt, D.S.2
Laxova, R.3
Hogan, K.4
-
38
-
-
0038122897
-
Severe methylenetetrahydrofolate reductase deficiency, methionine synthase, and nitrous oxide: A cautionary tale
-
Erbe RW, Salis RJ: Severe methylenetetrahydrofolate reductase deficiency, methionine synthase, and nitrous oxide: A cautionary tale. N Engl J Med 2003; 349:5-6
-
(2003)
N Engl J Med
, vol.349
, pp. 5-6
-
-
Erbe, R.W.1
Salis, R.J.2
-
39
-
-
13144261678
-
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction
-
Bond C, LaForge KS, Tian M, Melia D, Zhang S, Borg L, Gong J, Schluger J, Strong JA, Leal SM, Tischfield JA, Kreek MJ, Yu L: Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction. Proc Natl Acad Sci USA 1998; 95:9608-13
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9608-9613
-
-
Bond, C.1
Laforge, K.S.2
Tian, M.3
Melia, D.4
Zhang, S.5
Borg, L.6
Gong, J.7
Schluger, J.8
Strong, J.A.9
Leal, S.M.10
Tischfield, J.A.11
Kreek, M.J.12
Yu, L.13
-
40
-
-
0036792226
-
Does the A118G polymorphism at the μ-opioid receptor gene protect against morphine-6-glucuronide toxicity?
-
Lotsch J, Zimmermann M, Darimont J, Marx C, Dudziak R, Skarke C, Geisslinger G: Does the A118G polymorphism at the μ-opioid receptor gene protect against morphine-6-glucuronide toxicity? ANESTHESIOLOGY 2002; 97:814-9
-
(2002)
Anesthesiology
, vol.97
, pp. 814-819
-
-
Lotsch, J.1
Zimmermann, M.2
Darimont, J.3
Marx, C.4
Dudziak, R.5
Skarke, C.6
Geisslinger, G.7
-
41
-
-
0037261291
-
Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers
-
Skarke C, Darimont J, Schmidt H, Geisslinger G, Lotsch J: Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers. Clin Pharmacol Ther 2003; 73:107-21
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 107-121
-
-
Skarke, C.1
Darimont, J.2
Schmidt, H.3
Geisslinger, G.4
Lotsch, J.5
-
42
-
-
0033529255
-
The mu opiate receptor as a candidate gene for pain: Polymorphisms, variations in expression, nociception, and opiate responses
-
Uhl GR, Sora I, Wang Z: The mu opiate receptor as a candidate gene for pain: polymorphisms, variations in expression, nociception, and opiate responses. Proc Natl Acad Sci U S A 1999; 96:7752-5
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7752-7755
-
-
Uhl, G.R.1
Sora, I.2
Wang, Z.3
-
43
-
-
0038209379
-
A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine
-
Sawyer MB, Innocenti F, Das S, Cheng C, Ramirez J, Pantle-Fisher FH, Wright C, Badner J, Pei D, Boyett JM, Cook E Jr, Ratain MJ: A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine. Clin Pharmacol Ther 2003; 73:566-74
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 566-574
-
-
Sawyer, M.B.1
Innocenti, F.2
Das, S.3
Cheng, C.4
Ramirez, J.5
Pantle-Fisher, F.H.6
Wright, C.7
Badner, J.8
Pei, D.9
Boyett, J.M.10
Cook Jr., E.11
Ratain, M.J.12
-
44
-
-
0030472254
-
Codeine and morphine in extensive and poor metabolizers of sparteine: Pharmacokinetics, analgesic effect and side effects
-
Poulsen L, Brosen K, Arendt-Nielsen L, Gram LF, Elbaek K, Sindrup SH: Codeine and morphine in extensive and poor metabolizers of sparteine: Pharmacokinetics, analgesic effect and side effects. Eur J Clin Pharmacol 1996; 51:289-95
-
(1996)
Eur J Clin Pharmacol
, vol.51
, pp. 289-295
-
-
Poulsen, L.1
Brosen, K.2
Arendt-Nielsen, L.3
Gram, L.F.4
Elbaek, K.5
Sindrup, S.H.6
-
45
-
-
0032954826
-
Duplication, multiduplication, and amplification of genes encoding drug-metabolizing enzymes: Evolutionary, toxicological, and clinical pharmacological aspects
-
Ingelman-Sundberg M: Duplication, multiduplication, and amplification of genes encoding drug-metabolizing enzymes: Evolutionary, toxicological, and clinical pharmacological aspects. Drug Metab Rev 1999; 31:449-59
-
(1999)
Drug Metab Rev
, vol.31
, pp. 449-459
-
-
Ingelman-Sundberg, M.1
-
46
-
-
0031746749
-
Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation
-
Eckhardt K, Li S, Ammon S, Schanzle G, Mikus G, Eichelbaum M: Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation. Pain 1998; 76:27-33
-
(1998)
Pain
, vol.76
, pp. 27-33
-
-
Eckhardt, K.1
Li, S.2
Ammon, S.3
Schanzle, G.4
Mikus, G.5
Eichelbaum, M.6
-
47
-
-
0342981500
-
Impact of P450 genetic polymorphism on the first-pass extraction of cardiovascular and neuroactive drugs
-
Eichelbaum M, Kroemer HK, Fromm MF: Impact of P450 genetic polymorphism on the first-pass extraction of cardiovascular and neuroactive drugs. Adv Drug Deliv Rev 1997; 27:171-99
-
(1997)
Adv Drug Deliv Rev
, vol.27
, pp. 171-199
-
-
Eichelbaum, M.1
Kroemer, H.K.2
Fromm, M.F.3
-
48
-
-
0037955819
-
Codeine and clinical impairment in samples in which morphine is not detected
-
Bachs L, Skurtveit S, Morland J: Codeine and clinical impairment in samples in which morphine is not detected. Eur J Clin Pharmacol 2003; 58:785-9
-
(2003)
Eur J Clin Pharmacol
, vol.58
, pp. 785-789
-
-
Bachs, L.1
Skurtveit, S.2
Morland, J.3
-
49
-
-
0043127371
-
Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood
-
Levo A, Koski A, Ojanpera I, Vuori E, Sajahtila A: Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood. Forensic Sci Int 2003; 135:9-15
-
(2003)
Forensic Sci Int
, vol.135
, pp. 9-15
-
-
Levo, A.1
Koski, A.2
Ojanpera, I.3
Vuori, E.4
Sajahtila, A.5
-
50
-
-
0141626841
-
Impact of CYP2D6 genotype on postoperative tramadol analgesia
-
Stamer UM, Lehnen K, Hothker F, Bayerer B, Wolf S, Hoeft A, Stuber F: Impact of CYP2D6 genotype on postoperative tramadol analgesia. Pain 2003; 105:231-8
-
(2003)
Pain
, vol.105
, pp. 231-238
-
-
Stamer, U.M.1
Lehnen, K.2
Hothker, F.3
Bayerer, B.4
Wolf, S.5
Hoeft, A.6
Stuber, F.7
-
51
-
-
0035100677
-
Cytochrome P450 2D6 genotype and methadone steady-state concentrations
-
Eap CB, Broly F, Mino A, Hammig R, Deglon JJ, Uehlinger C, Meili D, Chevalley AF, Bertschy G, Zullino D, Kosel M, Preisig M, Baumann P: Cytochrome P450 2D6 genotype and methadone steady-state concentrations. J Clin Psychopharmacol 2001; 21:229-34
-
(2001)
J Clin Psychopharmacol
, vol.21
, pp. 229-234
-
-
Eap, C.B.1
Broly, F.2
Mino, A.3
Hammig, R.4
Deglon, J.J.5
Uehlinger, C.6
Meili, D.7
Chevalley, A.F.8
Bertschy, G.9
Zullino, D.10
Kosel, M.11
Preisig, M.12
Baumann, P.13
-
52
-
-
0042530185
-
A discordance between cytochrome P450 2D6 genotype and phenotype in patients undergoing methadone maintenance treatment
-
Shiran MR, Chowdry J, Rostami-Hodjegan A, Ellis SW, Lennard MS, Iqbal MZ, Lagundoye O, Seivewright N, Tucker GT: A discordance between cytochrome P450 2D6 genotype and phenotype in patients undergoing methadone maintenance treatment. Br J Clin Pharmacol 2003; 56:220-4
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 220-224
-
-
Shiran, M.R.1
Chowdry, J.2
Rostami-Hodjegan, A.3
Ellis, S.W.4
Lennard, M.S.5
Iqbal, M.Z.6
Lagundoye, O.7
Seivewright, N.8
Tucker, G.T.9
-
53
-
-
0029944684
-
Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes
-
Iribarne C, Berthou F, Baird S, Dreano Y, Picart D, Bail JP, Beaune P, Menez JF: Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes. Chem Res Toxicol 1996; 9:365-73
-
(1996)
Chem Res Toxicol
, vol.9
, pp. 365-373
-
-
Iribarne, C.1
Berthou, F.2
Baird, S.3
Dreano, Y.4
Picart, D.5
Bail, J.P.6
Beaune, P.7
Menez, J.F.8
-
54
-
-
0032903876
-
Methadone N-demethylation in human liver microsomes: Lack of stereoselectivity and involvement of CYP3A4
-
Foster DJ, Somogyi AA, Bochner F: Methadone N-demethylation in human liver microsomes: Lack of stereoselectivity and involvement of CYP3A4. Br J Clin Pharmacol 1999; 47:403-12
-
(1999)
Br J Clin Pharmacol
, vol.47
, pp. 403-412
-
-
Foster, D.J.1
Somogyi, A.A.2
Bochner, F.3
-
55
-
-
0030739468
-
Possible involvement of multiple cytochrome P450S in fentanyl and sufentanil metabolism as opposed to alfentanil
-
Guitton J, Buronfosse T, Desage M, Lepape A, Brazier JL, Beaune P: Possible involvement of multiple cytochrome P450S in fentanyl and sufentanil metabolism as opposed to alfentanil. Biochem Pharmacol 1997; 53:1613-9
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 1613-1619
-
-
Guitton, J.1
Buronfosse, T.2
Desage, M.3
Lepape, A.4
Brazier, J.L.5
Beaune, P.6
-
56
-
-
0030868233
-
The role of cytochrome P450 3A4 in alfentanil clearance: Implications for interindividual variability in disposition and perioperative drug interactions
-
Kharasch ED, Russell M, Mautz D, Thummel KE, Kunze KL, Bowdle A, Cox K: The role of cytochrome P450 3A4 in alfentanil clearance: Implications for interindividual variability in disposition and perioperative drug interactions. ANESTHESIOLOGY 1997; 87:36-50
-
(1997)
Anesthesiology
, vol.87
, pp. 36-50
-
-
Kharasch, E.D.1
Russell, M.2
Mautz, D.3
Thummel, K.E.4
Kunze, K.L.5
Bowdle, A.6
Cox, K.7
-
57
-
-
0033858570
-
Gender differences in opioid-mediated analgesia: Animal and human studies
-
Kest B, Sarton E, Dahan A: Gender differences in opioid-mediated analgesia: Animal and human studies. ANESTHESIOLOGY 2000; 93:539-47
-
(2000)
Anesthesiology
, vol.93
, pp. 539-547
-
-
Kest, B.1
Sarton, E.2
Dahan, A.3
-
58
-
-
0037458277
-
COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor
-
Zubieta JK, Heitzeg MM, Smith YR, Bueller JA, Xu K, Xu Y, Koeppe RA, Stohler CS, Goldman D: COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor. Science 2003; 299:1240-3
-
(2003)
Science
, vol.299
, pp. 1240-1243
-
-
Zubieta, J.K.1
Heitzeg, M.M.2
Smith, Y.R.3
Bueller, J.A.4
Xu, K.5
Xu, Y.6
Koeppe, R.A.7
Stohler, C.S.8
Goldman, D.9
-
59
-
-
0028918413
-
Kinetics of human soluble and membrane-bound catechol O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme
-
Lotta T, Vidgren J, Tilgmann C, Ulmanen I, Melen K, Julkunen I, Taskinen J: Kinetics of human soluble and membrane-bound catechol O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 1995; 34:4202-10
-
(1995)
Biochemistry
, vol.34
, pp. 4202-4210
-
-
Lotta, T.1
Vidgren, J.2
Tilgmann, C.3
Ulmanen, I.4
Melen, K.5
Julkunen, I.6
Taskinen, J.7
-
60
-
-
0030836682
-
High-activity catechol-O-methyltransferase allele is more prevalent in polysubstance abusers
-
Vandenbergh DJ, Rodriguez LA, Miller IT, Uhl GR, Lachman HM. High-activity catechol-O-methyltransferase allele is more prevalent in polysubstance abusers. Am J Med Genet 1997; 74:439-42
-
(1997)
Am J Med Genet
, vol.74
, pp. 439-442
-
-
Vandenbergh, D.J.1
Rodriguez, L.A.2
Miller, I.T.3
Uhl, G.R.4
Lachman, H.M.5
-
61
-
-
0035810850
-
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia
-
Egan MF, Goldberg TE, Kolachana BS, Callicott JH, Mazzanti CM, Straub RE, Goldman D, Weinberger DR: Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A 2001; 98:6917-22
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6917-6922
-
-
Egan, M.F.1
Goldberg, T.E.2
Kolachana, B.S.3
Callicott, J.H.4
Mazzanti, C.M.5
Straub, R.E.6
Goldman, D.7
Weinberger, D.R.8
-
62
-
-
0034723054
-
Opioid receptor and peptide gene polymorphisms: Potential implications for addictions
-
LaForge KS, Yuferov V, Kreek MJ: Opioid receptor and peptide gene polymorphisms: potential implications for addictions. Eur J Pharmacol 2000; 410:249-68
-
(2000)
Eur J Pharmacol
, vol.410
, pp. 249-268
-
-
Laforge, K.S.1
Yuferov, V.2
Kreek, M.J.3
-
63
-
-
1642299385
-
Genes associated with addiction: Alcoholism, opiate, and cocaine addiction
-
Kreek MJ, Nielsen DA, LaForge KS: Genes associated with addiction: Alcoholism, opiate, and cocaine addiction. Neuromolecular Med 2004; 5:85-108
-
(2004)
Neuromolecular Med
, vol.5
, pp. 85-108
-
-
Kreek, M.J.1
Nielsen, D.A.2
Laforge, K.S.3
-
64
-
-
0036431725
-
Oxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenase
-
Sandberg M, Yasar U, Stromberg P, Hoog JO, Eliasson E: Oxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenase. Br J Clin Pharmacol 2002; 54:423-9
-
(2002)
Br J Clin Pharmacol
, vol.54
, pp. 423-429
-
-
Sandberg, M.1
Yasar, U.2
Stromberg, P.3
Hoog, J.O.4
Eliasson, E.5
-
65
-
-
0041381141
-
Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites
-
Kirchheiner J, Stormer E, Meisel C, Steinbach N, Roots I, Brockmoller J: Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites. Pharmacogenetics 2003; 13:473-80
-
(2003)
Pharmacogenetics
, vol.13
, pp. 473-480
-
-
Kirchheiner, J.1
Stormer, E.2
Meisel, C.3
Steinbach, N.4
Roots, I.5
Brockmoller, J.6
-
66
-
-
0036206152
-
Polymorphic variants (CYP2C9*3 and CYP2C9*5) and the F114L active site mutation of CYP2C9: Effect on atypical kinetic metabolism profiles
-
Tracy TS, Hutzler JM, Haining RL, Rettie AE, Hummel MA, Dickmann LJ: Polymorphic variants (CYP2C9*3 and CYP2C9*5) and the F114L active site mutation of CYP2C9: Effect on atypical kinetic metabolism profiles. Drug Metab Dispos 2002; 30:385-90
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 385-390
-
-
Tracy, T.S.1
Hutzler, J.M.2
Haining, R.L.3
Rettie, A.E.4
Hummel, M.A.5
Dickmann, L.J.6
-
67
-
-
0035052562
-
In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: Correlation with CYP2C9 genotype and in-vivo pharmacokinetics
-
Tang C, Shou M, Rushmore TH, Mei Q, Sandhu P, Woolf EJ, Rose MJ, Gelmann A, Greenberg HE, De L, I, Van Hecken A, De Schepper PJ, Ebel DL, Schwanz JI, Rodrigues AD: In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: Correlation with CYP2C9 genotype and in-vivo pharmacokinetics. Pharmacogenetics 2001; 11:223-35
-
(2001)
Pharmacogenetics
, vol.11
, pp. 223-235
-
-
Tang, C.1
Shou, M.2
Rushmore, T.H.3
Mei, Q.4
Sandhu, P.5
Woolf, E.J.6
Rose, M.J.7
Gelmann, A.8
Greenberg, H.E.9
De, L.I.10
Van Hecken, A.11
De Schepper, P.J.12
Ebel, D.L.13
Schwanz, J.I.14
Rodrigues, A.D.15
-
68
-
-
0036336114
-
Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2
-
Kirchheiner J, Meineke I, Freytag G, Meisel C, Roots I, Brockmoller J: Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. Clin Pharmacol Ther 2002; 72:62-75
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 62-75
-
-
Kirchheiner, J.1
Meineke, I.2
Freytag, G.3
Meisel, C.4
Roots, I.5
Brockmoller, J.6
-
69
-
-
0037214177
-
Tolbutamide, flurbiprofen, and losartan as probes of CYP2C9 activity in humans
-
Lee CR, Pieper JA, Frye RF, Hinderliter AL, Blaisdell JA, Goldstein JA: Tolbutamide, flurbiprofen, and losartan as probes of CYP2C9 activity in humans. J Clin Pharmacol 2003; 43:84-91
-
(2003)
J Clin Pharmacol
, vol.43
, pp. 84-91
-
-
Lee, C.R.1
Pieper, J.A.2
Frye, R.F.3
Hinderliter, A.L.4
Blaisdell, J.A.5
Goldstein, J.A.6
-
70
-
-
0035667562
-
The role of CYP2C9 genotype in the metabolism of diclofenac in vivo and in vitro
-
Yasar U, Eliasson E, Forslund-Bergengren C, Tybring G, Gadd M, Sjoqvist F, Dahl ML: The role of CYP2C9 genotype in the metabolism of diclofenac in vivo and in vitro. Eur J Clin Pharmacol 2001; 57:729-35
-
(2001)
Eur J Clin Pharmacol
, vol.57
, pp. 729-735
-
-
Yasar, U.1
Eliasson, E.2
Forslund-Bergengren, C.3
Tybring, G.4
Gadd, M.5
Sjoqvist, F.6
Dahl, M.L.7
-
71
-
-
0037226087
-
Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib
-
Brenner SS, Herrlinger C, Dilger K, Murdter TE, Hofmann U, Marx C, Klotz U: Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib. Clin Pharmacokinet 2003; 42:283-92
-
(2003)
Clin Pharmacokinet
, vol.42
, pp. 283-292
-
-
Brenner, S.S.1
Herrlinger, C.2
Dilger, K.3
Murdter, T.E.4
Hofmann, U.5
Marx, C.6
Klotz, U.7
-
72
-
-
0033816613
-
Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis
-
Aithal GP, Day CP, Leathart JB, Daly AK: Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis. Pharmacogenetics 2000; 10:511-8
-
(2000)
Pharmacogenetics
, vol.10
, pp. 511-518
-
-
Aithal, G.P.1
Day, C.P.2
Leathart, J.B.3
Daly, A.K.4
-
73
-
-
0029878392
-
Acetaminophen metabolism in patients with different cytochrome P-4502E1 genotypes
-
Ueshima Y, Tsutsumi M, Takase S, Matsuda Y, Kawahara H: Acetaminophen metabolism in patients with different cytochrome P-4502E1 genotypes. Alcohol Clin Exp Res 1996; 20:25A-8A
-
(1996)
Alcohol Clin Exp Res
, vol.20
-
-
Ueshima, Y.1
Tsutsumi, M.2
Takase, S.3
Matsuda, Y.4
Kawahara, H.5
-
74
-
-
0032125487
-
Tumor necrosis factor genomic polymorphism and outcome of acetaminophen (paracetamol)-induced acute liver failure
-
Bernal W, Donaldson P, Underbill J, Wendon J, Williams R: Tumor necrosis factor genomic polymorphism and outcome of acetaminophen (paracetamol)-induced acute liver failure. J Hepatol 1998; 29:53-9
-
(1998)
J Hepatol
, vol.29
, pp. 53-59
-
-
Bernal, W.1
Donaldson, P.2
Underbill, J.3
Wendon, J.4
Williams, R.5
-
75
-
-
0033022590
-
Association of HLA-DR11 with the anaphylactoid reaction caused by nonsteroidal anti-inflammatory drugs
-
Quiralte J, Sanchez-Garcia F, Torres MJ, Blanco C, Castillo R, Ortega N, de Castro FR, Perez-Aciego P, Carrillo T: Association of HLA-DR11 with the anaphylactoid reaction caused by nonsteroidal anti-inflammatory drugs. J Allergy Clin Immunol 1999; 103:685-9
-
(1999)
J Allergy Clin Immunol
, vol.103
, pp. 685-689
-
-
Quiralte, J.1
Sanchez-Garcia, F.2
Torres, M.J.3
Blanco, C.4
Castillo, R.5
Ortega, N.6
De Castro, F.R.7
Perez-Aciego, P.8
Carrillo, T.9
-
76
-
-
0034764480
-
Functional characterization of cyclooxygenase-2 polymorphisms
-
Pritsche E, Baek SJ, King LM, Zeldin DC, Eling TE, Bell DA: Functional characterization of cyclooxygenase-2 polymorphisms. J Pharmacol Exp Ther 2001; 299:468-76
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 468-476
-
-
Pritsche, E.1
Baek, S.J.2
King, L.M.3
Zeldin, D.C.4
Eling, T.E.5
Bell, D.A.6
-
77
-
-
2342504605
-
A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke
-
Cipollone F, Toniato E, Martinotti S, Fazia M, Iezzi A, Cuccurullo C, Pini B, Ursi S, Vitullo G, Averna M, Area M, Montali A, Campagna F, Ucchino S, Spigonardo F, Taddei S, Virdis A, Ciabattoni G, Notarbartolo A, Cuccurullo F, Mezzetti A: A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke. JAMA 2004; 291:2221-8
-
(2004)
JAMA
, vol.291
, pp. 2221-2228
-
-
Cipollone, F.1
Toniato, E.2
Martinotti, S.3
Fazia, M.4
Iezzi, A.5
Cuccurullo, C.6
Pini, B.7
Ursi, S.8
Vitullo, G.9
Averna, M.10
Area, M.11
Montali, A.12
Campagna, F.13
Ucchino, S.14
Spigonardo, F.15
Taddei, S.16
Virdis, A.17
Ciabattoni, G.18
Notarbartolo, A.19
Cuccurullo, F.20
Mezzetti, A.21
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