메뉴 건너뛰기




Volumn 11, Issue 5, 2010, Pages 421-433

Mice in ecstasy: Advanced animal models in the study of MDMA

Author keywords

3,4 methylenedioxymethamphetamine; Ecstasy; Knock out; MDMA; Mouse models; Review; Transgenic

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 4 AMINOBUTYRIC ACID; ACETYLCHOLINE; ALPHA 2A ADRENERGIC RECEPTOR; CANNABINOID 1 RECEPTOR; CYTOCHROME P450 2D6; DOPAMINE; DOPAMINE RECEPTOR; ENKEPHALIN; MU OPIATE RECEPTOR; NALOXONE; NEURONAL NITRIC OXIDE SYNTHASE; NORADRENALIN; OREXIN; PSYCHOSTIMULANT AGENT; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR;

EID: 77956593988     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920110791591508     Document Type: Article
Times cited : (6)

References (137)
  • 1
    • 0034767580 scopus 로고    scopus 로고
    • An exploration of the history and controversies surrounding MDMA and MDA
    • Pentney, A. R. An exploration of the history and controversies surrounding MDMA and MDA. J. Psychoactive Drugs, 2001, 33(3), 213-221.
    • (2001) J. Psychoactive Drugs , vol.33 , Issue.3 , pp. 213-221
    • Pentney, A.R.1
  • 3
    • 33744943282 scopus 로고    scopus 로고
    • A review of the acute subjective effects of MDMA/ecstasy
    • Baylen, C.A.; Rosenberg, H. A review of the acute subjective effects of MDMA/ecstasy. Addiction, 2006, 101(7), 933-947.
    • (2006) Addiction , vol.101 , Issue.7 , pp. 933-947
    • Baylen, C.A.1    Rosenberg, H.2
  • 5
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: Insights into human neurobiology
    • Murphy, D. L.; Lesch, K. P. Targeting the murine serotonin transporter: insights into human neurobiology. Nat. Rev. Neurosci., 2008, 9(2), 85-96.
    • (2008) Nat. Rev. Neurosci , vol.9 , Issue.2 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.P.2
  • 6
    • 0025281065 scopus 로고
    • Reversal of the acute effects of 3,4-methylenedioxymethamphetamine by 5-HT uptake inhibitors
    • Schmidt, C. J.; Taylor, V. L. Reversal of the acute effects of 3,4-methylenedioxymethamphetamine by 5-HT uptake inhibitors. Eur. J. Pharmacol., 1990, 181(1-2), 133-136.
    • (1990) Eur. J. Pharmacol , vol.181 , Issue.1-2 , pp. 133-136
    • Schmidt, C.J.1    Taylor, V.L.2
  • 7
    • 0034852341 scopus 로고    scopus 로고
    • The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brain
    • Sanchez, V.; Camarero, J.; Esteban, B.; Peter, M. J.; Green, A. R.; Colado, M. I. The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brain. Br. J. Pharmacol., 2001, 134(1), 46-57.
    • (2001) Br. J. Pharmacol , vol.134 , Issue.1 , pp. 46-57
    • Sanchez, V.1    Camarero, J.2    Esteban, B.3    Peter, M.J.4    Green, A.R.5    Colado, M.I.6
  • 8
    • 69449095628 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of ecstasy-neurotoxicity: An overview
    • Capela, J. P.; Carmo, H.; Remiao, F.; Bastos, M. L.; Meisel, A.; Carvalho, F. Molecular and cellular mechanisms of ecstasy-neurotoxicity: an overview. Mol. Neurobiol., 2009, 39(3), 210-271.
    • (2009) Mol. Neurobiol , vol.39 , Issue.3 , pp. 210-271
    • Capela, J.P.1    Carmo, H.2    Remiao, F.3    Bastos, M.L.4    Meisel, A.5    Carvalho, F.6
  • 9
    • 0035012074 scopus 로고    scopus 로고
    • 3,4-methylenedioxy-methamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions
    • Bankson, M.G.; Cunningham, K.A. 3,4-methylenedioxy-methamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions. J. Pharmacol. Exp. Ther., 2001, 297(3), 846-852.
    • (2001) J. Pharmacol. Exp. Ther , vol.297 , Issue.3 , pp. 846-852
    • Bankson, M.G.1    Cunningham, K.A.2
  • 10
    • 0029067178 scopus 로고
    • Review of the pharmacology and clinical-pharmacology of 3,4-methylenedioxy-methamphetamine (MDMA or ecstasy)
    • Green, A. R.; Cross, A. J.; Goodwin, G. M. Review of the pharmacology and clinical-pharmacology of 3,4-methylenedioxy-methamphetamine (MDMA or ecstasy). Psychopharmacology, 1995, 119(3), 247-260.
    • (1995) Psychopharmacology , vol.119 , Issue.3 , pp. 247-260
    • Green, A.R.1    Cross, A.J.2    Goodwin, G.M.3
  • 11
    • 0023914535 scopus 로고
    • Pharmacologic profile of mdma (3,4-methylenedioxy-methamphetamine) at various brain recognition sites
    • Battaglia, G.; Brooks, B. P.; Kulsakdinun, C.; Desouza, E. B. Pharmacologic profile of mdma (3,4-methylenedioxy-methamphetamine) at various brain recognition sites. Eur. J. Pharmacol., 1988, 149(1-2), 159-163.
    • (1988) Eur. J. Pharmacol , vol.149 , Issue.1-2 , pp. 159-163
    • Battaglia, G.1    Brooks, B.P.2    Kulsakdinun, C.3    Desouza, E.B.4
  • 12
    • 68749089945 scopus 로고    scopus 로고
    • A structured review of reasons for ecstasy use and related behaviours: Pointers for future research
    • Peters, G. J. Y.; Kok, G. A structured review of reasons for ecstasy use and related behaviours: pointers for future research. BMC Public Health, 2009, 9, 230.
    • (2009) BMC Public Health , vol.9 , pp. 230
    • Peters, G.J.Y.1    Kok, G.2
  • 13
    • 36849053811 scopus 로고    scopus 로고
    • Social cognitive determinants of ecstasy use to target in evidence-based interventions: A meta-analytical review
    • Peters, G. J. Y.; Kok, G.; Abraham, C. Social cognitive determinants of ecstasy use to target in evidence-based interventions: a meta-analytical review. Addiction, 2008, 103(1), 109-118.
    • (2008) Addiction , vol.103 , Issue.1 , pp. 109-118
    • Peters, G.J.Y.1    Kok, G.2    Abraham, C.3
  • 14
    • 56349086517 scopus 로고    scopus 로고
    • Careers in ecstasy use: Do ecstasy users cease of their own accord? Implications for intervention development
    • Peters, G. J. Y.; Kok, G.; Schaalma, H. P. Careers in ecstasy use: do ecstasy users cease of their own accord? Implications for intervention development. BMC Public Health, 2008, 8, 376.
    • (2008) BMC Public Health , vol.8 , pp. 376
    • Peters, G.J.Y.1    Kok, G.2    Schaalma, H.P.3
  • 15
    • 0034925477 scopus 로고    scopus 로고
    • Patterns of recreational drug use at dance events in Edinburgh, Scotland
    • Riley, S. C.; James, C.; Gregory, D.; Dingle, H.; Cadger, M. Patterns of recreational drug use at dance events in Edinburgh, Scotland. Addiction, 2001, 96(7), 1035-1047.
    • (2001) Addiction , vol.96 , Issue.7 , pp. 1035-1047
    • Riley, S.C.1    James, C.2    Gregory, D.3    Dingle, H.4    Cadger, M.5
  • 16
    • 0036695012 scopus 로고    scopus 로고
    • Ecstasy and drug consumption patterns: A Canadian rave population study
    • Gross, S. R.; Barrett, S. P.; Shestowsky, J. S.; Pihl, R. O. Ecstasy and drug consumption patterns: a Canadian rave population study. Can. J. Psychiatry, 2002, 47(6), 546-551.
    • (2002) Can. J. Psychiatry , vol.47 , Issue.6 , pp. 546-551
    • Gross, S.R.1    Barrett, S.P.2    Shestowsky, J.S.3    Pihl, R.O.4
  • 17
    • 33745910208 scopus 로고    scopus 로고
    • Patterns of simultaneous polysubstance use in drug using university students
    • Barrett, S. P.; Darredeau, C.; Pihl, R. O. Patterns of simultaneous polysubstance use in drug using university students. Hum. Psychopharm. Clin., 2006, 21(4), 255-263.
    • (2006) Hum. Psychopharm. Clin , vol.21 , Issue.4 , pp. 255-263
    • Barrett, S.P.1    Darredeau, C.2    Pihl, R.O.3
  • 18
    • 23244433068 scopus 로고    scopus 로고
    • Patterns of simultaneous polysubstance use in Canadian rave attendees
    • Barrett, S. P.; Gross, S. R.; Garand, I.; Pihl, R. O. Patterns of simultaneous polysubstance use in Canadian rave attendees. Subst. Use Misuse, 2005, 40(9-10), 1525-1537.
    • (2005) Subst. Use Misuse , vol.40 , Issue.9-10 , pp. 1525-1537
    • Barrett, S.P.1    Gross, S.R.2    Garand, I.3    Pihl, R.O.4
  • 19
    • 27844592691 scopus 로고    scopus 로고
    • Pharmacological aspects of the combined use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and gamma-hydroxybutyric acid (GHB): A review of the literature
    • Uys, J. D.; Niesink, R. J. Pharmacological aspects of the combined use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and gamma-hydroxybutyric acid (GHB): a review of the literature. Drug Alcohol Rev., 2005, 24(4), 359-368.
    • (2005) Drug Alcohol Rev , vol.24 , Issue.4 , pp. 359-368
    • Uys, J.D.1    Niesink, R.J.2
  • 20
    • 33746819929 scopus 로고    scopus 로고
    • The confounding problem of polydrug use in recreational ecstasy/MDMA users: A brief overview
    • Gouzoulis-Mayfrank, E.; Daumann, J. The confounding problem of polydrug use in recreational ecstasy/MDMA users: a brief overview. J. Psychopharmacol., 2006, 20(2), 188-193.
    • (2006) J. Psychopharmacol , vol.20 , Issue.2 , pp. 188-193
    • Gouzoulis-Mayfrank, E.1    Daumann, J.2
  • 21
    • 58649098129 scopus 로고    scopus 로고
    • Equasy--an overlooked addiction with implications for the current debate on drug harms
    • Nutt, D. J. Equasy--an overlooked addiction with implications for the current debate on drug harms. J. Psychopharmacol., 2009, 23(1), 3-5.
    • (2009) J. Psychopharmacol , vol.23 , Issue.1 , pp. 3-5
    • Nutt, D.J.1
  • 22
    • 12444321929 scopus 로고    scopus 로고
    • Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy
    • Parrott, A. C. Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy. J. Psychopharmacol., 2005, 19(1), 71-83.
    • (2005) J. Psychopharmacol , vol.19 , Issue.1 , pp. 71-83
    • Parrott, A.C.1
  • 24
    • 4544314351 scopus 로고    scopus 로고
    • Neurotoxicity of MDMA (ecstasy): The limitations of scaling from animals to humans
    • de la Torre, R.; Farre, M. Neurotoxicity of MDMA (ecstasy): the limitations of scaling from animals to humans. Trends Pharmacol. Sci., 2004, 25(10), 505-508.
    • (2004) Trends Pharmacol. Sci , vol.25 , Issue.10 , pp. 505-508
    • de la Torre, R.1    Farre, M.2
  • 25
    • 33646073783 scopus 로고    scopus 로고
    • Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs
    • Han, D. D.; Gu, H. H. Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs. BMC Pharmacol., 2006, 6, 6.
    • (2006) BMC Pharmacol , vol.6 , pp. 6
    • Han, D.D.1    Gu, H.H.2
  • 26
    • 0242576358 scopus 로고    scopus 로고
    • Monoamine transporters and psychostimulant drugs
    • Rothman, R. B.; Baumann, M. H. Monoamine transporters and psychostimulant drugs. Eur. J. Pharmacol., 2003, 479(1-3), 23-40.
    • (2003) Eur. J. Pharmacol , vol.479 , Issue.1-3 , pp. 23-40
    • Rothman, R.B.1    Baumann, M.H.2
  • 27
    • 0030909052 scopus 로고    scopus 로고
    • MDMA induced dopamine release in vivo: Role of endogenous serotonin
    • Koch, S.; Galloway, M. P. MDMA induced dopamine release in vivo: Role of endogenous serotonin. J. Neural Transm., 1997, 104(2-3), 135-146.
    • (1997) J. Neural Transm , vol.104 , Issue.2-3 , pp. 135-146
    • Koch, S.1    Galloway, M.P.2
  • 28
    • 33646871323 scopus 로고    scopus 로고
    • Acute toxic effects of 'Ecstasy' (MDMA) and related compounds: Overview of pathophysiology and clinical management
    • Hall, A. P.; Henry, J. A. Acute toxic effects of 'Ecstasy' (MDMA) and related compounds: overview of pathophysiology and clinical management. Brit. J. Anaesth., 2006, 96(6), 678-685.
    • (2006) Brit. J. Anaesth , vol.96 , Issue.6 , pp. 678-685
    • Hall, A.P.1    Henry, J.A.2
  • 29
    • 0041466261 scopus 로고    scopus 로고
    • The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)
    • Green, A. R.; Mechan, A. O.; Elliott, J. M.; O'Shea, E.; Colado, M. I. The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy). Pharmacol. Rev., 2003, 55(3), 463-508.
    • (2003) Pharmacol. Rev , vol.55 , Issue.3 , pp. 463-508
    • Green, A.R.1    Mechan, A.O.2    Elliott, J.M.3    O'Shea, E.4    Colado, M.I.5
  • 30
    • 1042266417 scopus 로고    scopus 로고
    • Amphetamine neurotoxicity: Accomplishments and remaining challenges
    • McCann, U. D.; Ricaurte, G. A. Amphetamine neurotoxicity: accomplishments and remaining challenges. Neurosci. Biobehav. Rev., 2004, 27(8), 821-826.
    • (2004) Neurosci. Biobehav. Rev , vol.27 , Issue.8 , pp. 821-826
    • McCann, U.D.1    Ricaurte, G.A.2
  • 32
    • 0029112473 scopus 로고
    • The hyperthermic and neurotoxic effects of ecstasy (Mdma) and 3,4-methylene-dioxyamphetamine (Mda) in the dark-agouti (Da) rat, a Model of the Cyp2D6 poor metabolizer phenotype
    • Colado, M. I.; Williams, J. L.; Green, A. R. The hyperthermic and neurotoxic effects of ecstasy (Mdma) and 3,4-methylene-dioxyamphetamine (Mda) in the dark-agouti (Da) rat, a Model of the Cyp2D6 poor metabolizer phenotype. Brit. J. Pharmacol., 1995, 115(7), 1281-1289.
    • (1995) Brit. J. Pharmacol , vol.115 , Issue.7 , pp. 1281-1289
    • Colado, M.I.1    Williams, J.L.2    Green, A.R.3
  • 35
    • 0036965857 scopus 로고    scopus 로고
    • CYP2D6 deficiency, a factor in ecstasy related deaths?
    • Gilhooly, T. C.; Daly, A. K. CYP2D6 deficiency, a factor in ecstasy related deaths? Br. J. Clin. Pharmacol., 2002, 54(1), 69-70.
    • (2002) Br. J. Clin. Pharmacol , vol.54 , Issue.1 , pp. 69-70
    • Gilhooly, T.C.1    Daly, A.K.2
  • 36
    • 0031846978 scopus 로고    scopus 로고
    • MDMA toxicity: No evidence for a major influence of metabolic genotype at CYP2D6
    • O'Donohoe, A.; O'Flynn, K.; Shields, K.; Hawi, Z.; Gill, M. MDMA toxicity: No evidence for a major influence of metabolic genotype at CYP2D6. Addict. Biol., 1998, 3(3), 309-314.
    • (1998) Addict. Biol , vol.3 , Issue.3 , pp. 309-314
    • O'Donohoe, A.1    O'Flynn, K.2    Shields, K.3    Hawi, Z.4    Gill, M.5
  • 39
    • 0642366710 scopus 로고    scopus 로고
    • V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans
    • Krebsfaenger, N.; Murdter, T. E.; Zanger, U. M.; Eichelbaum, M. F.; Doehmer, J. V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans. Altex, 2003, 20(3), 143-154.
    • (2003) Altex , vol.20 , Issue.3 , pp. 143-154
    • Krebsfaenger, N.1    Murdter, T.E.2    Zanger, U.M.3    Eichelbaum, M.F.4    Doehmer, J.5
  • 40
    • 68949192657 scopus 로고    scopus 로고
    • Drug transporters: Gatekeepers controlling access of xenobiotics to the cellular interior
    • Stanley, L. A.; Horsburgh, B. C.; Ross, J.; Scheer, N.; Wolf, C. R. Drug transporters: gatekeepers controlling access of xenobiotics to the cellular interior. Drug Metab. Rev., 2009, 41(1), 27-65.
    • (2009) Drug Metab. Rev , vol.41 , Issue.1 , pp. 27-65
    • Stanley, L.A.1    Horsburgh, B.C.2    Ross, J.3    Scheer, N.4    Wolf, C.R.5
  • 41
    • 0030832634 scopus 로고    scopus 로고
    • Differential toxic effects of methamphetamine (METH) and methy-lenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice
    • Mann, H.; Ladenheim, B.; Hirata, H.; Moran, T. H.; Cadet, J. L. Differential toxic effects of methamphetamine (METH) and methy-lenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice. Brain Res., 1997, 769(2), 340-346.
    • (1997) Brain Res , vol.769 , Issue.2 , pp. 340-346
    • Mann, H.1    Ladenheim, B.2    Hirata, H.3    Moran, T.H.4    Cadet, J.L.5
  • 42
    • 43249126070 scopus 로고    scopus 로고
    • Fluoxetine pretreatment effects pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, ECSTASY) in rat
    • Upreti, V. V.; Eddington, N. D. Fluoxetine pretreatment effects pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, ECSTASY) in rat. J. Pharm. Sci., 2008, 97(4), 1593-1605.
    • (2008) J. Pharm. Sci , vol.97 , Issue.4 , pp. 1593-1605
    • Upreti, V.V.1    Eddington, N.D.2
  • 43
    • 77956670575 scopus 로고    scopus 로고
    • Mice lacking multidrug resistance protein 1a show altered dopaminergic responses to methylenedioxymethamphetamine (MDMA) in striatum
    • doi: 10.1007/s12640-009-9124-z
    • Scheidweiler, K. B.; Ladenheim, B.; Cadet, J. L.; Huestis, M. A. Mice lacking multidrug resistance protein 1a show altered dopaminergic responses to methylenedioxymethamphetamine (MDMA) in striatum. Neurotox. Res., 2009, doi: 10.1007/s12640-009-9124-z.
    • (2009) Neurotox. Res
    • Scheidweiler, K.B.1    Ladenheim, B.2    Cadet, J.L.3    Huestis, M.A.4
  • 44
    • 0033012485 scopus 로고    scopus 로고
    • 5-HT receptor knockout mice: Pharmacological tools or models of psychiatric disorders
    • Scearce-Levie, K.; Chen, J. P.; Gardner, E.; Hen, R. 5-HT receptor knockout mice: Pharmacological tools or models of psychiatric disorders. Ann. N. Y. Acad. Sci., 1999, 868, 701-715.
    • (1999) Ann. N. Y. Acad. Sci , vol.868 , pp. 701-715
    • Scearce-Levie, K.1    Chen, J.P.2    Gardner, E.3    Hen, R.4
  • 45
    • 0032898984 scopus 로고    scopus 로고
    • Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor
    • Scearce-Levie, K.; Viswanathan, S. S.; Hen, R. Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor. Psychopharmacology, 1999, 141(2), 154-161.
    • (1999) Psychopharmacology , vol.141 , Issue.2 , pp. 154-161
    • Scearce-Levie, K.1    Viswanathan, S.S.2    Hen, R.3
  • 46
    • 40849142489 scopus 로고    scopus 로고
    • Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro
    • Doly, S.; Valjent, E.; Setola, V.; Callebert, J.; Herve, D.; Launay, J. M.; Maroteaux, L. Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro. J. Neurosci., 2008, 28(11), 2933-2940.
    • (2008) J. Neurosci , vol.28 , Issue.11 , pp. 2933-2940
    • Doly, S.1    Valjent, E.2    Setola, V.3    Callebert, J.4    Herve, D.5    Launay, J.M.6    Maroteaux, L.7
  • 47
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymethamphetamine (ecstasy) in serotonin transporter-deficient mice
    • Bengel, D.; Murphy, D. L.; Andrews, A. M.; Wichems, C. H.; Feltner, D.; Heils, A.; Mossner, R.; Westphal, H.; Lesch, K. P. Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymethamphetamine (ecstasy) in serotonin transporter-deficient mice. Mol. Pharmacol., 1998, 53(4), 649-655.
    • (1998) Mol. Pharmacol , vol.53 , Issue.4 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3    Wichems, C.H.4    Feltner, D.5    Heils, A.6    Mossner, R.7    Westphal, H.8    Lesch, K.P.9
  • 48
    • 33847112557 scopus 로고    scopus 로고
    • Serotonin and psychostimulant addiction: Focus on 5-HT1A-receptors
    • Muller, C. P.; Carey, R. J.; Huston, J. P.; Silva, M. A. D. Serotonin and psychostimulant addiction: Focus on 5-HT1A-receptors. Prog. Neurobiol., 2007, 81(3), 133-178.
    • (2007) Prog. Neurobiol , vol.81 , Issue.3 , pp. 133-178
    • Muller, C.P.1    Carey, R.J.2    Huston, J.P.3    Silva, M.A.D.4
  • 49
    • 0036020333 scopus 로고    scopus 로고
    • Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: Studies on locomotor activity and responding for conditioned reinforcement
    • Fletcher, P. J.; Korth, K. M.; Robinson, S. R.; Baker, G. B. Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: studies on locomotor activity and responding for conditioned reinforcement. Psychopharmacology, 2002, 162(3), 282-291.
    • (2002) Psychopharmacology , vol.162 , Issue.3 , pp. 282-291
    • Fletcher, P.J.1    Korth, K.M.2    Robinson, S.R.3    Baker, G.B.4
  • 50
    • 34548149262 scopus 로고    scopus 로고
    • 3,4-methylenedioxymethamphetamine self-administration is abolished in serotonin transporter knockout mice
    • Trigo, J. M.; Renoir, T.; Lanfumey, L.; Hamon, M.; Lesch, K. P.; Robledo, P.; Maldonado, R. 3,4-methylenedioxymethamphetamine self-administration is abolished in serotonin transporter knockout mice. Biol. Psychiatry, 2007, 62(6), 669-679.
    • (2007) Biol. Psychiatry , vol.62 , Issue.6 , pp. 669-679
    • Trigo, J.M.1    Renoir, T.2    Lanfumey, L.3    Hamon, M.4    Lesch, K.P.5    Robledo, P.6    Maldonado, R.7
  • 51
    • 0027389036 scopus 로고
    • Non-neurotoxic amphetamine derivatives release serotonin through serotonin transporters
    • Rudnick, G.; Wall, S. C. Non-neurotoxic amphetamine derivatives release serotonin through serotonin transporters. Mol. Pharmacol., 1993, 43(2), 271-276.
    • (1993) Mol. Pharmacol , vol.43 , Issue.2 , pp. 271-276
    • Rudnick, G.1    Wall, S.C.2
  • 52
    • 0041942680 scopus 로고    scopus 로고
    • Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine
    • Compan, V.; Scearce-Levie, K.; Crosson, C.; Daszuta, A.; Hen, R. Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine. Eur. J. Neurosci., 2003, 18(2), 383-390.
    • (2003) Eur. J. Neurosci , vol.18 , Issue.2 , pp. 383-390
    • Compan, V.1    Scearce-Levie, K.2    Crosson, C.3    Daszuta, A.4    Hen, R.5
  • 54
    • 70350509637 scopus 로고    scopus 로고
    • Methamphetamine- and 3,4-Methylenedioxymethamphetamine-induced behavioral changes in histamine H-3-receptor knockout mice
    • Okuda, T.; Zhang, D. Y.; Shao, H.; Okamura, N.; Takino, N.; Iwamura, T.; Sakurai, E.; Yoshikawa, T.; Yanai, K. Methamphetamine- and 3,4-Methylenedioxymethamphetamine-induced behavioral changes in histamine H-3-receptor knockout mice. J. Pharmacol. Sci., 2009, 111(2), 167-174.
    • (2009) J. Pharmacol. Sci , vol.111 , Issue.2 , pp. 167-174
    • Okuda, T.1    Zhang, D.Y.2    Shao, H.3    Okamura, N.4    Takino, N.5    Iwamura, T.6    Sakurai, E.7    Yoshikawa, T.8    Yanai, K.9
  • 56
    • 10444258090 scopus 로고    scopus 로고
    • Differential response of nNOS knockout mice to MDMA (ecstasy)- and methamphetamine-induced psychomotor sensitization and neurotoxicity
    • Itzhak, Y.; Anderson, K. L.; Ali, S. F. Differential response of nNOS knockout mice to MDMA (ecstasy)- and methamphetamine-induced psychomotor sensitization and neurotoxicity. Ann. N. Y. Acad. Sci., 2004, 1025, 119-128.
    • (2004) Ann. N. Y. Acad. Sci , vol.1025 , pp. 119-128
    • Itzhak, Y.1    Anderson, K.L.2    Ali, S.F.3
  • 57
    • 33750222726 scopus 로고    scopus 로고
    • Differential contributions of dopamine D-1, D-2, and D-3 receptors to MDMA-induced effects on locomotor behavior patterns in mice
    • Risbrough, V. B.; Masten, V. L.; Caldwell, S.; Paulus, M. P.; Low, M. J.; Geyer, M. A. Differential contributions of dopamine D-1, D-2, and D-3 receptors to MDMA-induced effects on locomotor behavior patterns in mice. Neuropsychopharmacology, 2006, 31(11), 2349-2358.
    • (2006) Neuropsychopharmacology , vol.31 , Issue.11 , pp. 2349-2358
    • Risbrough, V.B.1    Masten, V.L.2    Caldwell, S.3    Paulus, M.P.4    Low, M.J.5    Geyer, M.A.6
  • 58
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros, B.; Jaber, M.; Jones, S. R.; Wightman, R. M.; Caron, M. G. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature, 1996, 379(6566), 606-612.
    • (1996) Nature , vol.379 , Issue.6566 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 59
    • 0032811146 scopus 로고    scopus 로고
    • Functional hyperdopaminergia in dopamine transporter knock-out mice
    • Gainetdinov, R. R.; Jones, S. R.; Caron, M. G. Functional hyperdopaminergia in dopamine transporter knock-out mice. Biol. Psychiatry, 1999, 46(3), 303-311.
    • (1999) Biol. Psychiatry , vol.46 , Issue.3 , pp. 303-311
    • Gainetdinov, R.R.1    Jones, S.R.2    Caron, M.G.3
  • 60
    • 0035143189 scopus 로고    scopus 로고
    • Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: Differential effects of D1 and D2 receptor antagonists
    • Ralph, R. J.; Paulus, M. P.; Fumagalli, F.; Caron, M. G.; Geyer, M. A. Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: Differential effects of D1 and D2 receptor antagonists. J. Neurosci., 2001, 21(1), 305-313.
    • (2001) J. Neurosci , vol.21 , Issue.1 , pp. 305-313
    • Ralph, R.J.1    Paulus, M.P.2    Fumagalli, F.3    Caron, M.G.4    Geyer, M.A.5
  • 61
  • 62
    • 23944502329 scopus 로고    scopus 로고
    • Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease
    • Sotnikova, T. D.; Beaulieu, J. M.; Barak, L. S.; Wetsel, W. C.; Caron, M. G.; Gainetdinov, R. R. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. PLoS Biol., 2005, 3(8), e271.
    • (2005) PLoS Biol , vol.3 , Issue.8
    • Sotnikova, T.D.1    Beaulieu, J.M.2    Barak, L.S.3    Wetsel, W.C.4    Caron, M.G.5    Gainetdinov, R.R.6
  • 63
    • 0037183772 scopus 로고    scopus 로고
    • Ecstasy counteracts catalepsy in rats, an anti-parkinsonian effect?
    • Schmidt, W. J.; Mayerhofer, A.; Meyer, A.; Kovar, K. A. Ecstasy counteracts catalepsy in rats, an anti-parkinsonian effect? Neurosci. Lett., 2002, 330(3), 251-254.
    • (2002) Neurosci. Lett , vol.330 , Issue.3 , pp. 251-254
    • Schmidt, W.J.1    Mayerhofer, A.2    Meyer, A.3    Kovar, K.A.4
  • 64
    • 55549117850 scopus 로고    scopus 로고
    • Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice
    • Renoir, T.; Paizanis, E.; Yacoubi, M.; Saurini, F.; Hanoun, N.; Melfort, M.; Lesch, K. P.; Hamon, M.; Lanfumey, L. Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice. Int. J. Neuropsychopharmacol., 2008, 11(8), 1149-1162.
    • (2008) Int. J. Neuropsychopharmacol , vol.11 , Issue.8 , pp. 1149-1162
    • Renoir, T.1    Paizanis, E.2    Yacoubi, M.3    Saurini, F.4    Hanoun, N.5    Melfort, M.6    Lesch, K.P.7    Hamon, M.8    Lanfumey, L.9
  • 65
    • 1642331289 scopus 로고    scopus 로고
    • Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone
    • Banasr, M.; Hery, M.; Printemps, R.; Daszuta, A. Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone. Neuropsychopharmacology, 2004, 29(3), 450-460.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.3 , pp. 450-460
    • Banasr, M.1    Hery, M.2    Printemps, R.3    Daszuta, A.4
  • 66
    • 34247872922 scopus 로고    scopus 로고
    • Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test
    • O'Leary, O. F.; Bechtholt, A. J.; Crowley, J. J.; Hill, T. E.; Page, M. E.; Lucki, I. Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test. Psychopharmacology, 2007, 192(3), 357-371.
    • (2007) Psychopharmacology , vol.192 , Issue.3 , pp. 357-371
    • O'Leary, O.F.1    Bechtholt, A.J.2    Crowley, J.J.3    Hill, T.E.4    Page, M.E.5    Lucki, I.6
  • 68
    • 1642488880 scopus 로고    scopus 로고
    • Chronic fluoxetine treatment partly attenuates the long-term anxiety and depressive symptoms induced by MDMA ('Ecstasy') in rats
    • Thompson, M. R.; Li, K. M.; Clemens, K. J.; Gurtman, C. G.; Hunt, G. E.; Cornish, J. L.; McGregor, I. S. Chronic fluoxetine treatment partly attenuates the long-term anxiety and depressive symptoms induced by MDMA ('Ecstasy') in rats. Neuropsychopharmacology, 2004, 29(4), 694-704.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.4 , pp. 694-704
    • Thompson, M.R.1    Li, K.M.2    Clemens, K.J.3    Gurtman, C.G.4    Hunt, G.E.5    Cornish, J.L.6    McGregor, I.S.7
  • 69
    • 4143146481 scopus 로고    scopus 로고
    • Identification and characterization of metallothionein-1 and-2 gene expression in the context of (+/-)3,4-methylenedioxy-methamphetamine-induced toxicity to brain dopaminergic neurons
    • Xie, T.; Tong, L. Q.; McCann, U. D.; Yuan, J.; Becker, K. G.; Mechan, A. O.; Cheadle, C.; Donovan, D. M.; Ricaurte, G. A. Identification and characterization of metallothionein-1 and-2 gene expression in the context of (+/-)3,4-methylenedioxy-methamphetamine-induced toxicity to brain dopaminergic neurons. J. Neurosci., 2004, 24(32), 7043-7050.
    • (2004) J. Neurosci , vol.24 , Issue.32 , pp. 7043-7050
    • Xie, T.1    Tong, L.Q.2    McCann, U.D.3    Yuan, J.4    Becker, K.G.5    Mechan, A.O.6    Cheadle, C.7    Donovan, D.M.8    Ricaurte, G.A.9
  • 71
    • 59649085915 scopus 로고    scopus 로고
    • The metallothionein/thionein system: An oxidoreductive metabolic zinc link
    • Bell, S. G.; Vallee, B. L. The metallothionein/thionein system: An oxidoreductive metabolic zinc link. Chembiochem., 2009, 10(1), 55-62.
    • (2009) Chembiochem , vol.10 , Issue.1 , pp. 55-62
    • Bell, S.G.1    Vallee, B.L.2
  • 72
    • 4644304559 scopus 로고    scopus 로고
    • Methamphetamine and MDMA (ecstasy) neurotoxicity: 'of mice and men'
    • Itzhak, Y.; Achat-Mendes, C. Methamphetamine and MDMA (ecstasy) neurotoxicity: 'of mice and men'. IUBMB Life, 2004, 56(5), 249-255.
    • (2004) IUBMB Life , vol.56 , Issue.5 , pp. 249-255
    • Itzhak, Y.1    Achat-Mendes, C.2
  • 73
    • 0027978346 scopus 로고
    • Cuzn superoxide-dismutase (Cuznsod) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (Mda) and of methylenedioxymethamphetamine (Mdma)
    • Cadet, J. L.; Ladenheim, B.; Baum, I.; Carlson, E.; Epstein, C. Cuzn superoxide-dismutase (Cuznsod) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (Mda) and of methylenedioxymethamphetamine (Mdma). Brain Res., 1994, 655(1-2), 259-262.
    • (1994) Brain Res , vol.655 , Issue.1-2 , pp. 259-262
    • Cadet, J.L.1    Ladenheim, B.2    Baum, I.3    Carlson, E.4    Epstein, C.5
  • 74
    • 0029126705 scopus 로고
    • Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (Mdma) - evidence from using cuzn-Superoxide dismutase transgenic mice
    • Cadet, J. L.; Ladenheim, B.; Hirata, H.; Rothman, R. B.; Ali, S.; Carlson, E.; Epstein, C.; Moran, T. H. Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (Mdma) - evidence from using cuzn-Superoxide dismutase transgenic mice. Synapse, 1995, 21(2), 169-176.
    • (1995) Synapse , vol.21 , Issue.2 , pp. 169-176
    • Cadet, J.L.1    Ladenheim, B.2    Hirata, H.3    Rothman, R.B.4    Ali, S.5    Carlson, E.6    Epstein, C.7    Moran, T.H.8
  • 75
    • 0032903612 scopus 로고    scopus 로고
    • Overexpression of human copper zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxy-methamphetamine (ecstasy)
    • Jayanthi, S.; Ladenheim, B.; Andrews, A. M.; Cadet, J. L. Overexpression of human copper zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxy-methamphetamine (ecstasy). Neuroscience, 1999, 91(4), 1379-1387.
    • (1999) Neuroscience , vol.91 , Issue.4 , pp. 1379-1387
    • Jayanthi, S.1    Ladenheim, B.2    Andrews, A.M.3    Cadet, J.L.4
  • 76
    • 0032969675 scopus 로고    scopus 로고
    • In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism
    • Colado, M. I.; O'Shea, E.; Esteban, B.; Granados, R.; Green, A. R. In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism. Neuropharmacology, 1999, 38(2), 307-314.
    • (1999) Neuropharmacology , vol.38 , Issue.2 , pp. 307-314
    • Colado, M.I.1    O'Shea, E.2    Esteban, B.3    Granados, R.4    Green, A.R.5
  • 77
    • 0030986255 scopus 로고    scopus 로고
    • In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine
    • Colado, M. I.; OShea, E.; Granados, R.; Murray, T. K.; Green, A. R. In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine. Br. J. Pharmacol., 1997, 121(5), 889-900.
    • (1997) Br. J. Pharmacol , vol.121 , Issue.5 , pp. 889-900
    • Colado, M.I.1    Oshea, E.2    Granados, R.3    Murray, T.K.4    Green, A.R.5
  • 78
    • 0031594132 scopus 로고    scopus 로고
    • Resistance of neuronal nitric oxide synthase-deficient mice to methamphetamine-induced dopaminergic neurotoxicity
    • Itzhak, Y.; Gandia, C.; Huang, P. L.; Ali, S. F. Resistance of neuronal nitric oxide synthase-deficient mice to methamphetamine-induced dopaminergic neurotoxicity. J. Pharmacol. Exp. Ther., 1998, 284(3), 1040-1047.
    • (1998) J. Pharmacol. Exp. Ther , vol.284 , Issue.3 , pp. 1040-1047
    • Itzhak, Y.1    Gandia, C.2    Huang, P.L.3    Ali, S.F.4
  • 81
    • 0032750752 scopus 로고    scopus 로고
    • Striatal dopamine metabolism in monoamine oxidase B-deficient mice: A brain dialysis study
    • Fornai, F.; Chen, K.; Giorgi, F. S.; Gesi, M.; Alessandri, M. G.; Shih, J. C. Striatal dopamine metabolism in monoamine oxidase B-deficient mice: a brain dialysis study. J. Neurochem., 1999, 73(6), 2434-2440.
    • (1999) J. Neurochem , vol.73 , Issue.6 , pp. 2434-2440
    • Fornai, F.1    Chen, K.2    Giorgi, F.S.3    Gesi, M.4    Alessandri, M.G.5    Shih, J.C.6
  • 82
    • 0035283681 scopus 로고    scopus 로고
    • Biochemical effects of the monoamine neurotoxins DSP-4 and MDMA in specific brain regions of MAO-B-deficient mice
    • Fornai, F.; Giorgi, F. S.; Gesi, M.; Chen, K.; Alessandri, M. G.; Shih, J. C. Biochemical effects of the monoamine neurotoxins DSP-4 and MDMA in specific brain regions of MAO-B-deficient mice. Synapse, 2001, 39(3), 213-221.
    • (2001) Synapse , vol.39 , Issue.3 , pp. 213-221
    • Fornai, F.1    Giorgi, F.S.2    Gesi, M.3    Chen, K.4    Alessandri, M.G.5    Shih, J.C.6
  • 83
    • 0028104042 scopus 로고
    • Mdma (ecstasy) inhibition of mao type-a and type-B - comparisons with fenfluramine and fluoxetine (prozac)
    • Leonardi, E. T. K.; Azmitia, E. C. Mdma (ecstasy) inhibition of mao type-a and type-B - comparisons with fenfluramine and fluoxetine (prozac). Neuropsychopharmacol., 1994, 10(4), 231-238.
    • (1994) Neuropsychopharmacol , vol.10 , Issue.4 , pp. 231-238
    • Leonardi, E.T.K.1    Azmitia, E.C.2
  • 84
    • 34447625084 scopus 로고    scopus 로고
    • Thermophysiological responses to hyperthermic drugs: Extrapolating from rodent to human
    • Gordon, C. J. Thermophysiological responses to hyperthermic drugs: extrapolating from rodent to human. Prog. Brain Res., 2007, 162, 63-79.
    • (2007) Prog. Brain Res , vol.162 , pp. 63-79
    • Gordon, C.J.1
  • 85
    • 0032125256 scopus 로고    scopus 로고
    • Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat
    • Malberg, J. E.; Seiden, L. S. Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat. J. Neurosci., 1998, 18(13), 5086-5094.
    • (1998) J. Neurosci , vol.18 , Issue.13 , pp. 5086-5094
    • Malberg, J.E.1    Seiden, L.S.2
  • 86
    • 0027964301 scopus 로고
    • Environment-induced, drug-induced and stress-induced alterations in body-temperature affect the neurotoxicity of substituted Amphetamines in the C57Bl/6J Mouse
    • Miller, D. B.; Ocallaghan, J. P. Environment-induced, drug-induced and stress-induced alterations in body-temperature affect the neurotoxicity of substituted Amphetamines in the C57Bl/6J Mouse. J. Pharmacol. Exp. Ther., 1994, 270(2), 752-760.
    • (1994) J. Pharmacol. Exp. Ther , vol.270 , Issue.2 , pp. 752-760
    • Miller, D.B.1    Ocallaghan, J.P.2
  • 87
    • 43049170002 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor modulates 3,4-methylenedioxymethamphetamine acute responses and reinforcement
    • Touriño, C.; Ledent, C.; Maldonado, R.; Valverde, O. CB1 cannabinoid receptor modulates 3,4-methylenedioxymethamphetamine acute responses and reinforcement. Biol. Psychiatry, 2008, 63(11), 1030-1038.
    • (2008) Biol. Psychiatry , vol.63 , Issue.11 , pp. 1030-1038
    • Touriño, C.1    Ledent, C.2    Maldonado, R.3    Valverde, O.4
  • 88
    • 0032585937 scopus 로고    scopus 로고
    • Investigation of the prejunctional alpha(2)-adrenoceptor mediated actions of MDMA in rat atrium and vas deferens
    • Lavelle, A.; Honner, V.; Docherty, J. R. Investigation of the prejunctional alpha(2)-adrenoceptor mediated actions of MDMA in rat atrium and vas deferens. Br. J. Pharmacol., 1999, 128(5), 975-980.
    • (1999) Br. J. Pharmacol , vol.128 , Issue.5 , pp. 975-980
    • Lavelle, A.1    Honner, V.2    Docherty, J.R.3
  • 89
    • 0034762682 scopus 로고    scopus 로고
    • Vascular actions of MDMA involve alpha(1) and alpha(2)-adrenoceptors in the anaesthetized rat
    • McDaid, J.; Docherty, J. R. Vascular actions of MDMA involve alpha(1) and alpha(2)-adrenoceptors in the anaesthetized rat. Br. J. Pharmacol., 2001, 133(3), 429-437.
    • (2001) Br. J. Pharmacol , vol.133 , Issue.3 , pp. 429-437
    • McDaid, J.1    Docherty, J.R.2
  • 90
    • 30644457692 scopus 로고    scopus 로고
    • Role of alpha(2A)-adrenoceptors in the effects of MDMA on body temperature in the mouse
    • Bexis, S.; Docherty, J. R. Role of alpha(2A)-adrenoceptors in the effects of MDMA on body temperature in the mouse. Br. J. Pharmacol., 2005, 146(1), 1-6.
    • (2005) Br. J. Pharmacol , vol.146 , Issue.1 , pp. 1-6
    • Bexis, S.1    Docherty, J.R.2
  • 91
    • 12444322029 scopus 로고    scopus 로고
    • The role of the sympathetic nervous system and uncoupling proteins in the thermogenesis induced by 3,4-methylenedioxymethamphetamine
    • Mills, E. M.; Rusyniak, D. E.; Sprague, J. E. The role of the sympathetic nervous system and uncoupling proteins in the thermogenesis induced by 3,4-methylenedioxymethamphetamine. J. Mol. Med., 2004, 82(12), 787-799.
    • (2004) J. Mol. Med , vol.82 , Issue.12 , pp. 787-799
    • Mills, E.M.1    Rusyniak, D.E.2    Sprague, J.E.3
  • 92
    • 0344982956 scopus 로고    scopus 로고
    • Pharmacology: Uncoupling the agony from ecstasy - a mitochondrial protein may mediate a dangerous side-effect of some recreational drugs
    • Mills, E. M.; Banks, M. L.; Sprague, J. E.; Finkel, T. Pharmacology: uncoupling the agony from ecstasy - a mitochondrial protein may mediate a dangerous side-effect of some recreational drugs. Nature, 2003, 426(6965), 403-404.
    • (2003) Nature , vol.426 , Issue.6965 , pp. 403-404
    • Mills, E.M.1    Banks, M.L.2    Sprague, J.E.3    Finkel, T.4
  • 95
    • 35349031067 scopus 로고    scopus 로고
    • The neuropsychology of ecstasy (MDMA) use: A quantitative review
    • Zakzanis, K. K.; Campbell, Z.; Jovanovski, D. The neuropsychology of ecstasy (MDMA) use: A quantitative review. Hum. Psychopharmacol., 2007, 22(7), 427-435.
    • (2007) Hum. Psychopharmacol , vol.22 , Issue.7 , pp. 427-435
    • Zakzanis, K.K.1    Campbell, Z.2    Jovanovski, D.3
  • 96
    • 33645330954 scopus 로고    scopus 로고
    • Patterns of memory dysfunction in current and 2-year abstinent MDMA users
    • Ward, J.; Hall, K.; Haslam, C. Patterns of memory dysfunction in current and 2-year abstinent MDMA users. J. Clin. Exp. Neuropsychol., 2006, 28(3), 306-324.
    • (2006) J. Clin. Exp. Neuropsychol , vol.28 , Issue.3 , pp. 306-324
    • Ward, J.1    Hall, K.2    Haslam, C.3
  • 97
    • 72449162513 scopus 로고    scopus 로고
    • A cannabinoid CB(1) receptor antagonist ameliorates impairment of recognition memory on withdrawal from MDMA (Ecstasy)
    • Nawata, Y.; Hiranita, T.; Yamamoto, T. A cannabinoid CB(1) receptor antagonist ameliorates impairment of recognition memory on withdrawal from MDMA (Ecstasy). Neuropsychopharmacol., 2010, 35(2), 515-520.
    • (2010) Neuropsychopharmacol , vol.35 , Issue.2 , pp. 515-520
    • Nawata, Y.1    Hiranita, T.2    Yamamoto, T.3
  • 98
    • 0035861913 scopus 로고    scopus 로고
    • Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine (Ecstasy)
    • Morley, K. C.; Gallate, J. E.; Hunt, G. E.; Mallet, P. E.; McGregor, I. S. Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine (Ecstasy). Eur. J. Pharmacol., 2001, 433(1), 91-99.
    • (2001) Eur. J. Pharmacol , vol.433 , Issue.1 , pp. 91-99
    • Morley, K.C.1    Gallate, J.E.2    Hunt, G.E.3    Mallet, P.E.4    McGregor, I.S.5
  • 99
    • 0041737712 scopus 로고    scopus 로고
    • Increased anxiety and 'depressive' symptoms months after MDMA ('ecstasy') in rats: Drug-induced hyperthermia does not predict long-term outcomes
    • McGregor, I. S.; Gurtman, C. G.; Morley, K. C.; Clemens, K. J.; Blokland, A.; Li, K. M.; Cornish, J. L.; Hunt, G. E. Increased anxiety and 'depressive' symptoms months after MDMA ('ecstasy') in rats: drug-induced hyperthermia does not predict long-term outcomes. Psychopharmacology, 2003, 168(4), 465-474.
    • (2003) Psychopharmacology , vol.168 , Issue.4 , pp. 465-474
    • McGregor, I.S.1    Gurtman, C.G.2    Morley, K.C.3    Clemens, K.J.4    Blokland, A.5    Li, K.M.6    Cornish, J.L.7    Hunt, G.E.8
  • 100
    • 10044258731 scopus 로고    scopus 로고
    • Memory deficit and reduced anxiety in young adult rats given repeated intermittent MDMA treatment during the periadolescent period
    • Piper, B. J.; Meyer, J. S. Memory deficit and reduced anxiety in young adult rats given repeated intermittent MDMA treatment during the periadolescent period. Pharmacol. Biochem. Behav., 2004, 79(4), 723-731.
    • (2004) Pharmacol. Biochem. Behav , vol.79 , Issue.4 , pp. 723-731
    • Piper, B.J.1    Meyer, J.S.2
  • 101
    • 0025108906 scopus 로고
    • Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats
    • Callaway, C. W.; Wing, L. L.; Geyer, M. A. Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats. J. Pharmacol. Exp. Ther., 1990, 254(2), 456-464.
    • (1990) J. Pharmacol. Exp. Ther , vol.254 , Issue.2 , pp. 456-464
    • Callaway, C.W.1    Wing, L.L.2    Geyer, M.A.3
  • 102
    • 67049098280 scopus 로고    scopus 로고
    • S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA
    • Kindlundh-Hogberg, A. M. S.; Zhang, X. Q.; Svenningsson, P. S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA. Int. J. Neuropsychopharmacol., 2009, 12(2), 201-215.
    • (2009) Int. J. Neuropsychopharmacol , vol.12 , Issue.2 , pp. 201-215
    • Kindlundh-Hogberg, A.M.S.1    Zhang, X.Q.2    Svenningsson, P.3
  • 103
    • 0032534296 scopus 로고    scopus 로고
    • 5-HT1B receptor modulation of prepulse inhibition: Recent findings in wild-tppe and 5HT(1B) knockout mice
    • Dulawa, S. C.; Hen, R.; Scearce-Levine, K.; Geyer, M. A. 5-HT1B receptor modulation of prepulse inhibition: Recent findings in wild-tppe and 5HT(1B) knockout mice. Ann. N Y Acad. Sci., 1998, 861, 79-84.
    • (1998) Ann. N Y Acad. Sci , vol.861 , pp. 79-84
    • Dulawa, S.C.1    Hen, R.2    Scearce-Levine, K.3    Geyer, M.A.4
  • 104
    • 46649110318 scopus 로고    scopus 로고
    • Realistic expectations of prepulse inhibition in translational models for schizophrenia research
    • Swerdlow, N. R.; Weber, M.; Qu, Y.; Light, G. A.; Braff, D. L. Realistic expectations of prepulse inhibition in translational models for schizophrenia research. Psychopharmacology, 2008, 199(3), 331-388.
    • (2008) Psychopharmacology , vol.199 , Issue.3 , pp. 331-388
    • Swerdlow, N.R.1    Weber, M.2    Qu, Y.3    Light, G.A.4    Braff, D.L.5
  • 105
    • 0034073387 scopus 로고    scopus 로고
    • Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice
    • Dulawa, S. C.; Scearce-Levie, K. A.; Hen, R.; Geyer, M. A. Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice. Psychopharmacology, 2000, 149(3), 306-312.
    • (2000) Psychopharmacology , vol.149 , Issue.3 , pp. 306-312
    • Dulawa, S.C.1    Scearce-Levie, K.A.2    Hen, R.3    Geyer, M.A.4
  • 106
    • 0033837504 scopus 로고    scopus 로고
    • Effects of strain and serotonergic agents on prepulse inhibition and habituation in mice
    • Dulawa, S. C.; Geyer, M. A. Effects of strain and serotonergic agents on prepulse inhibition and habituation in mice. Neuropharmacology, 2000, 39(11), 2170-2179.
    • (2000) Neuropharmacology , vol.39 , Issue.11 , pp. 2170-2179
    • Dulawa, S.C.1    Geyer, M.A.2
  • 107
    • 0033988308 scopus 로고    scopus 로고
    • Assessing prepulse inhibition of startle in wild-type and knockout mice
    • Geyer, M. A. Assessing prepulse inhibition of startle in wild-type and knockout mice. Psychopharmacology, 1999, 147(1), 11-13.
    • (1999) Psychopharmacology , vol.147 , Issue.1 , pp. 11-13
    • Geyer, M.A.1
  • 108
    • 0141918812 scopus 로고    scopus 로고
    • Reinforcing, subjective, and physiological effects of MDMA in humans: A comparison with damphetamine and mCPP
    • Tancer, M.; Johanson, C. E. Reinforcing, subjective, and physiological effects of MDMA in humans: a comparison with damphetamine and mCPP. Drug Alcohol Depend, 2003, 72(1), 33-44.
    • (2003) Drug Alcohol Depend , vol.72 , Issue.1 , pp. 33-44
    • Tancer, M.1    Johanson, C.E.2
  • 109
    • 70449496185 scopus 로고    scopus 로고
    • MDMA Self-administration in laboratory animals: A summary of the literature and proposal for future research
    • Schenk, S. MDMA Self-administration in laboratory animals: a summary of the literature and proposal for future research. Neuropsychobiology, 2009, 60(3-4), 130-136.
    • (2009) Neuropsychobiology , vol.60 , Issue.3-4 , pp. 130-136
    • Schenk, S.1
  • 110
    • 0025670175 scopus 로고
    • Methylenedioxymethamphetamines Capacity to Establish Place Preferences and Modify Intake of an Alcoholic Beverage
    • Bilsky, E. J.; Hui, Y. Z.; Hubbell, C. L.; Reid, L. D. Methylenedioxymethamphetamines Capacity to Establish Place Preferences and Modify Intake of an Alcoholic Beverage. Pharmacol. Biochem. Behav., 1990, 37(4), 633-638.
    • (1990) Pharmacol. Biochem. Behav , vol.37 , Issue.4 , pp. 633-638
    • Bilsky, E.J.1    Hui, Y.Z.2    Hubbell, C.L.3    Reid, L.D.4
  • 111
    • 1642396666 scopus 로고    scopus 로고
    • Study of the behavioural responses related to the potential addictive properties of MDMA in mice
    • Robledo, P.; Balerio, G.; Berrendero, F.; Maldonado, R. Study of the behavioural responses related to the potential addictive properties of MDMA in mice. Naunyn Schmiedebergs Arch. Pharmacol., 2004, 369(3), 338-349.
    • (2004) Naunyn Schmiedebergs Arch. Pharmacol , vol.369 , Issue.3 , pp. 338-349
    • Robledo, P.1    Balerio, G.2    Berrendero, F.3    Maldonado, R.4
  • 112
    • 30544451954 scopus 로고    scopus 로고
    • A reliable model of intravenous MDMA self-administration in naive mice
    • Trigo, J. M.; Panayi, F.; Soria, G.; Maldonado, R.; Robledo, P. A reliable model of intravenous MDMA self-administration in naive mice. Psychopharmacology, 2006, 184(2), 212-220.
    • (2006) Psychopharmacology , vol.184 , Issue.2 , pp. 212-220
    • Trigo, J.M.1    Panayi, F.2    Soria, G.3    Maldonado, R.4    Robledo, P.5
  • 113
    • 0022915401 scopus 로고
    • Self-administration of methylenedioxymethamphetamine (Mdma) by rhesus-monkeys
    • Beardsley, P. M.; Balster, R. L.; Harris, L. S. Self-administration of methylenedioxymethamphetamine (Mdma) by rhesus-monkeys. Drug Alcohol Depend, 1986, 18(2), 149-157.
    • (1986) Drug Alcohol Depend , vol.18 , Issue.2 , pp. 149-157
    • Beardsley, P.M.1    Balster, R.L.2    Harris, L.S.3
  • 114
    • 0023126510 scopus 로고
    • Self-injection of D,1-3,4-Methylenedioxymethamphetamine (mdma) in the baboon
    • Lamb, R.J.; Griffiths, R.R. Self-injection of D,1-3,4-Methylenedioxymethamphetamine (mdma) in the baboon. Psychopharmacology, 1987, 91(3), 268-272.
    • (1987) Psychopharmacology , vol.91 , Issue.3 , pp. 268-272
    • Lamb, R.J.1    Griffiths, R.R.2
  • 115
    • 33751213885 scopus 로고    scopus 로고
    • Reinforcing effects of methylenedioxy amphetamine congeners in rhesus monkeys: Are intravenous self-administration experiments relevant to MDMA neurotoxicity?
    • Fantegrossi, W. E. Reinforcing effects of methylenedioxy amphetamine congeners in rhesus monkeys: are intravenous self-administration experiments relevant to MDMA neurotoxicity? Psychopharmacology, 2007, 189(4), 471-482.
    • (2007) Psychopharmacology , vol.189 , Issue.4 , pp. 471-482
    • Fantegrossi, W.E.1
  • 116
    • 33751231719 scopus 로고    scopus 로고
    • Relevance of rodent models of intravenous MDMA self-administration to human MDMA consumption patterns
    • De La Garza, R.; Fabrizio, K. R.; Gupta, A. Relevance of rodent models of intravenous MDMA self-administration to human MDMA consumption patterns. Psychopharmacology, 2007, 189(4), 425-434.
    • (2007) Psychopharmacology , vol.189 , Issue.4 , pp. 425-434
    • de la Garza, R.1    Fabrizio, K.R.2    Gupta, A.3
  • 117
    • 1942519843 scopus 로고    scopus 로고
    • Effect of SCH 23390 on (+/-)-3,4-methylenedioxymethamphetamine hyperactivity and self-administration in rats
    • Daniela, E.; Brennan, K.; Gittings, D.; Hely, L.; Schenk, S. Effect of SCH 23390 on (+/-)-3,4-methylenedioxymethamphetamine hyperactivity and self-administration in rats. Pharmacol. Biochem. Behav., 2004, 77(4), 745-750.
    • (2004) Pharmacol. Biochem. Behav , vol.77 , Issue.4 , pp. 745-750
    • Daniela, E.1    Brennan, K.2    Gittings, D.3    Hely, L.4    Schenk, S.5
  • 118
    • 0035824948 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse
    • Cossu, G.; Ledent, C.; Fattore, L.; Imperato, A.; Bohme, G. A.; Parmentier, M.; Fratta, W. Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse. Behav. Brain Res., 2001, 118(1), 61-65.
    • (2001) Behav. Brain Res , vol.118 , Issue.1 , pp. 61-65
    • Cossu, G.1    Ledent, C.2    Fattore, L.3    Imperato, A.4    Bohme, G.A.5    Parmentier, M.6    Fratta, W.7
  • 120
    • 25144523091 scopus 로고    scopus 로고
    • Ethanol self-administration and ethanol conditioned place preference are reduced in mice lacking cannabinoid CB1 receptors
    • Thanos, P. K.; Dimitrakakis, E. S.; Rice, O.; Gifford, A.; Volkow, N. D. Ethanol self-administration and ethanol conditioned place preference are reduced in mice lacking cannabinoid CB1 receptors. Behav. Brain Res., 2005, 164(2), 206-213.
    • (2005) Behav. Brain Res , vol.164 , Issue.2 , pp. 206-213
    • Thanos, P.K.1    Dimitrakakis, E.S.2    Rice, O.3    Gifford, A.4    Volkow, N.D.5
  • 121
    • 0033777338 scopus 로고    scopus 로고
    • Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice
    • Martin, M.; Ledent, C.; Parmentier, M.; Maldonado, R.; Valverde, O. Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice. Eur. J. Neurosci., 2000, 12(11), 4038-4046.
    • (2000) Eur. J. Neurosci , vol.12 , Issue.11 , pp. 4038-4046
    • Martin, M.1    Ledent, C.2    Parmentier, M.3    Maldonado, R.4    Valverde, O.5
  • 122
    • 33645982868 scopus 로고    scopus 로고
    • Involvement of the endocannabinoid system in drug addiction
    • Maldonado, R.; Valverde, O.; Berrendero, F. Involvement of the endocannabinoid system in drug addiction. Trends Neurosci., 2006, 29(4), 225-232.
    • (2006) Trends Neurosci , vol.29 , Issue.4 , pp. 225-232
    • Maldonado, R.1    Valverde, O.2    Berrendero, F.3
  • 124
    • 19344370158 scopus 로고    scopus 로고
    • 3,4-N-methlenedioxymethamphetamine-induced hypophagia is maintained in 5-HT1B receptor knockout mice, but suppressed by the 5-HT2C receptor antagonist RS102221
    • Conductier, G.; Crosson, C.; Hen, R.; Bockaert, J.; Compan, V. 3,4-N-methlenedioxymethamphetamine-induced hypophagia is maintained in 5-HT1B receptor knockout mice, but suppressed by the 5-HT2C receptor antagonist RS102221. Neuropsychopharmacology, 2005, 30(6), 1056-1063.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.6 , pp. 1056-1063
    • Conductier, G.1    Crosson, C.2    Hen, R.3    Bockaert, J.4    Compan, V.5
  • 126
  • 130
    • 0037073606 scopus 로고    scopus 로고
    • Vascular actions of 3,4-methylenedioxymethamphetamine in alpha(2A/D)-adrenoceptor knockout mice
    • Vandeputte, C.; Docherty, J.R. Vascular actions of 3,4-methylenedioxymethamphetamine in alpha(2A/D)-adrenoceptor knockout mice. Eur. J. Pharmacol., 2002, 457(1), 45-49.
    • (2002) Eur. J. Pharmacol , vol.457 , Issue.1 , pp. 45-49
    • Vandeputte, C.1    Docherty, J.R.2
  • 131
    • 0035816467 scopus 로고    scopus 로고
    • Prejunctional actions of methylenedioxymethamphetamine in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice
    • Rajamani, K.; Leong, S.; Lavelle, A.; Docherty, J. R. Prejunctional actions of methylenedioxymethamphetamine in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice. Eur. J. Pharmacol., 2001, 423(2-3), 223-228.
    • (2001) Eur. J. Pharmacol , vol.423 , Issue.2-3 , pp. 223-228
    • Rajamani, K.1    Leong, S.2    Lavelle, A.3    Docherty, J.R.4
  • 133
    • 72449207509 scopus 로고    scopus 로고
    • Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes
    • Kalueff, A. V.; Olivier, J. D.; Nonkes, L. J.; Homberg, J. R. Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes. Neurosci. Biobehav. Rev., 2010, 34(3), 373-386.
    • (2010) Neurosci. Biobehav. Rev , vol.34 , Issue.3 , pp. 373-386
    • Kalueff, A.V.1    Olivier, J.D.2    Nonkes, L.J.3    Homberg, J.R.4
  • 134
    • 54049093244 scopus 로고    scopus 로고
    • Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals
    • van Boxtel, R.; Toonen, P. W.; Verheul, M.; van Roekel, H. S.; Nijman, I. J.; Guryev, V.; Cuppen, E. Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals. BMC Genomics, 2008, 9, 460.
    • (2008) BMC Genomics , vol.9 , pp. 460
    • van Boxtel, R.1    Toonen, P.W.2    Verheul, M.3    van Roekel, H.S.4    Nijman, I.J.5    Guryev, V.6    Cuppen, E.7
  • 136
    • 33845201282 scopus 로고    scopus 로고
    • Local knockdown of genes in the brain using small interfering RNA: A phenotypic comparison with knockout animals
    • Salahpour, A.; Medvedev, I. O.; Beaulieu, J. M.; Gainetdinov, R. R.; Caron, M. G. Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals. Biol. Psychiatry, 2007, 61(1), 65-69.
    • (2007) Biol. Psychiatry , vol.61 , Issue.1 , pp. 65-69
    • Salahpour, A.1    Medvedev, I.O.2    Beaulieu, J.M.3    Gainetdinov, R.R.4    Caron, M.G.5
  • 137
    • 0346216853 scopus 로고    scopus 로고
    • Local gene knockdown in the brain using viralmediated RNA interference
    • Hommel, J. D.; Sears, R. M.; Georgescu, D.; Simmons, D. L.; DiLeone, R. J. Local gene knockdown in the brain using viralmediated RNA interference. Nat. Med., 2003, 9(12), 1539-1544.
    • (2003) Nat. Med , vol.9 , Issue.12 , pp. 1539-1544
    • Hommel, J.D.1    Sears, R.M.2    Georgescu, D.3    Simmons, D.L.4    Dileone, R.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.