-
1
-
-
0026454919
-
Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2
-
Braun, W., Vasak, M., Robbins, A. H., Stout, C. D., Wagner, G., Kagi, J. H., and Wuthrich, K. (1992) Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2. Proc. Natl. Acad. Sci. USA 89, 10124-10128.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10124-10128
-
-
Braun, W.1
Vasak, M.2
Robbins, A.H.3
Stout, C.D.4
Wagner, G.5
Kagi, J.H.6
Wuthrich, K.7
-
2
-
-
0016211318
-
Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content
-
Kagi, J. H., Himmelhoch, S. R., Whanger, P. D., Bethune, J. L., and Vallee, B. L. (1974) Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content. J. Biol. Chem. 249, 3537-3542.
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 3537-3542
-
-
Kagi, J.H.1
Himmelhoch, S.R.2
Whanger, P.D.3
Bethune, J.L.4
Vallee, B.L.5
-
3
-
-
0035872463
-
Roles of the metallothionein family of proteins in the central nervous system
-
Hidalgo, J., Aschner, M., Zatta, P., and Vasak, M. (2001) Roles of the metallothionein family of proteins in the central nervous system. Brain. Res. Bull. 55, 133-145.
-
(2001)
Brain. Res. Bull.
, vol.55
, pp. 133-145
-
-
Hidalgo, J.1
Aschner, M.2
Zatta, P.3
Vasak, M.4
-
4
-
-
33749602354
-
Peptide folding, metal-binding mechanisms, and binding site structures in metallothioneins
-
Duncan, K. E., Ngu, T. T., Chan, J., Salgado, M. T., Merrifield, M. E., and Stillman, M. J. (2006) Peptide folding, metal-binding mechanisms, and binding site structures in metallothioneins. Exp. Biol. Med. (Maywood) 231, 1488-1499.
-
(2006)
Exp. Biol. Med. (Maywood)
, vol.231
, pp. 1488-1499
-
-
Duncan, K.E.1
Ngu, T.T.2
Chan, J.3
Salgado, M.T.4
Merrifield, M.E.5
Stillman, M.J.6
-
5
-
-
33644866812
-
Metallothionein disulfides are present in metallothionein-overexpressing transgenic mouse heart and increase under conditions of oxidative stress
-
Feng, W., Benz, F. W., Cai, J., Pierce, W. M., and Kang, Y. J. (2006) Metallothionein disulfides are present in metallothionein-overexpressing transgenic mouse heart and increase under conditions of oxidative stress. J. Biol. Chem. 281, 681-687.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 681-687
-
-
Feng, W.1
Benz, F.W.2
Cai, J.3
Pierce, W.M.4
Kang, Y.J.5
-
6
-
-
0034602705
-
Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein
-
Pearce, L. L., Gandley, R. E., Han, W., Wasserloos, K., Stitt, M., Kanai, A. J., McLaughlin, M. K., Pitt, B. R., and Levitan, E. S. (2000) Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein. Proc. Natl. Acad. Sci. USA 97, 477-482.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 477-482
-
-
Pearce, L.L.1
Gandley, R.E.2
Han, W.3
Wasserloos, K.4
Stitt, M.5
Kanai, A.J.6
McLaughlin, M.K.7
Pitt, B.R.8
Levitan, E.S.9
-
7
-
-
0035887211
-
Oxidative dimerization in metallothionein is a result of intermolecular disulphide bonds between cysteines in the alpha-domain
-
Zangger, K., Shen, G., Oz, G., Otvos, J. D., and Armitage, I. M. (2001) Oxidative dimerization in metallothionein is a result of intermolecular disulphide bonds between cysteines in the alpha-domain. Biochem. J. 359, 353-360.
-
(2001)
Biochem. J.
, vol.359
, pp. 353-360
-
-
Zangger, K.1
Shen, G.2
Oz, G.3
Otvos, J.D.4
Armitage, I.M.5
-
8
-
-
0020558451
-
The metallothionein-I gene maps to mouse chromosome 8: Implications for human Menkes' disease
-
Cox, D. R. and Palmiter, R. D. (1983) The metallothionein-I gene maps to mouse chromosome 8: implications for human Menkes' disease, Hum. Genet. 64, 61-64.
-
(1983)
Hum. Genet.
, vol.64
, pp. 61-64
-
-
Cox, D.R.1
Palmiter, R.D.2
-
9
-
-
0009798409
-
Human metallothionein genes are clustered on chromosome 16
-
Karin, M., Eddy, R. L., Henry, W. M., Haley, L. L., Byers, M. G., and Shows, T. B. (1984) Human metallothionein genes are clustered on chromosome 16. Proc. Natl. Acad. Sci. USA 81, 5494-5498.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 5494-5498
-
-
Karin, M.1
Eddy, R.L.2
Henry, W.M.3
Haley, L.L.4
Byers, M.G.5
Shows, T.B.6
-
10
-
-
0026631182
-
MT-III, a brain-specific member of the metallothionein gene family
-
Palmiter, R. D., Findley, S. D., Whitmore, T. E., and Durnam, D. M. (1992) MT-III, a brain-specific member of the metallothionein gene family. Proc. Natl. Acad. Sci. USA 89, 6333-6337.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6333-6337
-
-
Palmiter, R.D.1
Findley, S.D.2
Whitmore, T.E.3
Durnam, D.M.4
-
11
-
-
0028289610
-
Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia
-
Quaife, C. J., Findley, S. D., Erickson, J. C., Froelick, G. J., Kelly, E. J., Zambrowicz, B. P., and Palmiter, R. D. (1994) Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. Biochemistry 33, 7250-7259.
-
(1994)
Biochemistry
, vol.33
, pp. 7250-7259
-
-
Quaife, C.J.1
Findley, S.D.2
Erickson, J.C.3
Froelick, G.J.4
Kelly, E.J.5
Zambrowicz, B.P.6
Palmiter, R.D.7
-
12
-
-
0028168091
-
Characterisation of six additional human metallothionein genes
-
Stennard, F. A., Holloway, A. F., Hamilton, J., and West, A. K. (1994) Characterisation of six additional human metallothionein genes. Biochim. Biophys. Acta. 1218, 357-365.
-
(1994)
Biochim. Biophys. Acta.
, vol.1218
, pp. 357-365
-
-
Stennard, F.A.1
Holloway, A.F.2
Hamilton, J.3
West, A.K.4
-
13
-
-
0025222043
-
Human metallothionein genes: Structure of the functional locus at 16q13
-
West, A. K., Stallings, R., Hildebrand, C. E., Chiu, R., Karin, M., and Richards, R. I. (1990) Human metallothionein genes: structure of the functional locus at 16q13. Genomics 8, 513-518.
-
(1990)
Genomics
, vol.8
, pp. 513-518
-
-
West, A.K.1
Stallings, R.2
Hildebrand, C.E.3
Chiu, R.4
Karin, M.5
Richards, R.I.6
-
14
-
-
0036240239
-
Metallothionein: The multipurpose protein
-
Coyle, P., Philcox, J. C., Carey, L. C., and Rofe, A. M. (2002) Metallothionein: the multipurpose protein. Cell Mol. Life. Sci. 59, 627-647.
-
(2002)
Cell Mol. Life. Sci.
, vol.59
, pp. 627-647
-
-
Coyle, P.1
Philcox, J.C.2
Carey, L.C.3
Rofe, A.M.4
-
15
-
-
33646268801
-
Metallothioneins are multipurpose neuroprotectants during brain pathology
-
Penkowa, M. (2006) Metallothioneins are multipurpose neuroprotectants during brain pathology. FEBS J. 273, 1857-1870.
-
(2006)
FEBS J.
, vol.273
, pp. 1857-1870
-
-
Penkowa, M.1
-
16
-
-
0345276583
-
Signaling events for metallothionein induction
-
Haq, F., Mahoney, M., and Koropatnick, J. (2003) Signaling events for metallothionein induction. Mutat. Res. 533, 211-226.
-
(2003)
Mutat. Res.
, vol.533
, pp. 211-226
-
-
Haq, F.1
Mahoney, M.2
Koropatnick, J.3
-
17
-
-
0034053364
-
Induction, regulation, degradation, and biological significance of mammalian metallothioneins
-
Miles, A. T., Hawksworth, G. M., Beattie, J. H., and Rodilla, V. (2000) Induction, regulation, degradation, and biological significance of mammalian metallothioneins. Crit. Rev. Biochem. Mol. Biol. 35, 35-70.
-
(2000)
Crit. Rev. Biochem. Mol. Biol.
, vol.35
, pp. 35-70
-
-
Miles, A.T.1
Hawksworth, G.M.2
Beattie, J.H.3
Rodilla, V.4
-
18
-
-
0029257277
-
Disruption of the blood-brain interface in neonatal rat neocortex induces a transient expression of metallothionein in reactive astrocytes
-
Penkowa, M. and Moos, T. (1995) Disruption of the blood-brain interface in neonatal rat neocortex induces a transient expression of metallothionein in reactive astrocytes. Glia 13, 217-227.
-
(1995)
Glia
, vol.13
, pp. 217-227
-
-
Penkowa, M.1
Moos, T.2
-
19
-
-
33646821764
-
Metallothionein I+II expression and roles during neuropathology in the CNS
-
Penkowa, M. (2006) Metallothionein I+II expression and roles during neuropathology in the CNS. Dan. Med. Bull. 53, 105-121.
-
(2006)
Dan. Med. Bull.
, vol.53
, pp. 105-121
-
-
Penkowa, M.1
-
20
-
-
33750600258
-
Novel roles for metallothionein-I+II (MT-I+II) in defense responses, neurogenesis, and tissue restoration after traumatic brain injury: Insights from global gene expression profiling in wild-type and MT-I+II knockout mice
-
Penkowa, M., Caceres, M., Borup, R., Nielsen, F. C., Poulsen, C. B., Quintana, A., Molinero, A., Carrasco, J., Florit, S., Giralt, M., and Hidalgo, J. (2006) Novel roles for metallothionein-I+II (MT-I+II) in defense responses, neurogenesis, and tissue restoration after traumatic brain injury: insights from global gene expression profiling in wild-type and MT-I+II knockout mice. J. Neurosci. Res. 84, 1452-1474.
-
(2006)
J. Neurosci. Res.
, vol.84
, pp. 1452-1474
-
-
Penkowa, M.1
Caceres, M.2
Borup, R.3
Nielsen, F.C.4
Poulsen, C.B.5
Quintana, A.6
Molinero, A.7
Carrasco, J.8
Florit, S.9
Giralt, M.10
Hidalgo, J.11
-
21
-
-
0035056140
-
Zinc or copper deficiency-induced impaired inflammatory response to brain trauma may be caused by the concomitant metallothionein changes
-
Penkowa, M., Giralt, M., Thomsen, P. S., Carrasco, J., and Hidalgo, J. (2001) Zinc or copper deficiency-induced impaired inflammatory response to brain trauma may be caused by the concomitant metallothionein changes, J. Neurotrauma 18, 447-463.
-
(2001)
J. Neurotrauma
, vol.18
, pp. 447-463
-
-
Penkowa, M.1
Giralt, M.2
Thomsen, P.S.3
Carrasco, J.4
Hidalgo, J.5
-
22
-
-
33645843958
-
Specificity and divergence in the neurobiologic effects of different metallothioneins after brain injury
-
Penkowa, M., Tio, L., Giralt, M., Quintana, A., Molinero, A., Atrian, S., Vasak, M., and Hidalgo, J. (2006) Specificity and divergence in the neurobiologic effects of different metallothioneins after brain injury. J. Neurosci. Res. 83, 974-984.
-
(2006)
J. Neurosci. Res.
, vol.83
, pp. 974-984
-
-
Penkowa, M.1
Tio, L.2
Giralt, M.3
Quintana, A.4
Molinero, A.5
Atrian, S.6
Vasak, M.7
Hidalgo, J.8
-
23
-
-
0033119327
-
CNS wound healing is severely depressed in metallothionein I- and II-deficient mice
-
Penkowa, M., Carrasco, J., Giralt, M., Moos, T., and Hidalgo, J. (1999) CNS wound healing is severely depressed in metallothionein I- and II-deficient mice. J. Neurosci. 19, 2535-2545.
-
(1999)
J. Neurosci.
, vol.19
, pp. 2535-2545
-
-
Penkowa, M.1
Carrasco, J.2
Giralt, M.3
Moos, T.4
Hidalgo, J.5
-
24
-
-
0033871715
-
Altered central nervous system cytokine-growth factor expression profiles and angiogenesis in metallothionein- I+II deficient mice
-
Penkowa, M., Carrasco, J., Giralt, M., Molinero, A., Hernandez, J., Campbell, I. L., and Hidalgo, J. (2000) Altered central nervous system cytokine-growth factor expression profiles and angiogenesis in metallothionein- I+II deficient mice. J. Cereb. Blood Flow. Metab. 20, 1174-1189.
-
(2000)
J. Cereb. Blood Flow. Metab.
, vol.20
, pp. 1174-1189
-
-
Penkowa, M.1
Carrasco, J.2
Giralt, M.3
Molinero, A.4
Hernandez, J.5
Campbell, I.L.6
Hidalgo, J.7
-
25
-
-
0036148593
-
Metallothionein-1+2 protect the CNS after a focal brain injury
-
Giralt, M., Penkowa, M., Lago, N., Molinero, A., and Hidalgo, J. (2002) Metallothionein-1+2 protect the CNS after a focal brain injury. Exp. Neurol. 173, 114-128.
-
(2002)
Exp. Neurol.
, vol.173
, pp. 114-128
-
-
Giralt, M.1
Penkowa, M.2
Lago, N.3
Molinero, A.4
Hidalgo, J.5
-
26
-
-
0346457011
-
Neuron-glia communication: Metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury
-
Chung, R. S., Adlard, P. A., Dittmann, J., Vickers, J. C., Chuah, M. I., and West, A. K. (2004) Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury. J. Neurochem. 88, 454-461.
-
(2004)
J. Neurochem.
, vol.88
, pp. 454-461
-
-
Chung, R.S.1
Adlard, P.A.2
Dittmann, J.3
Vickers, J.C.4
Chuah, M.I.5
West, A.K.6
-
27
-
-
37249058422
-
New insight into the molecular pathways of metallothionein-mediated neuroprotection and regeneration
-
Chung, R. S., Hidalgo, J., and West, A. K. (2008) New insight into the molecular pathways of metallothionein-mediated neuroprotection and regeneration. J. Neurochem. 104, 14-20.
-
(2008)
J. Neurochem.
, vol.104
, pp. 14-20
-
-
Chung, R.S.1
Hidalgo, J.2
West, A.K.3
-
28
-
-
0242384608
-
The role of metallothionein II in neuronal differentiation and survival
-
Kohler, L. B., Berezin, V., Bock, E., and Penkowa, M. (2003) The role of metallothionein II in neuronal differentiation and survival. Brain Res. 992, 128-136.
-
(2003)
Brain Res.
, vol.992
, pp. 128-136
-
-
Kohler, L.B.1
Berezin, V.2
Bock, E.3
Penkowa, M.4
-
29
-
-
37249056581
-
Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family
-
Ambjorn, M., Asmussen, J. W., Lindstam, M., Gotfryd, K., Jacobsen, C., Kiselyov, V. V., Moestrup, S. K., Penkowa, M., Bock, E., and Berezin, V. (2008) Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family. J. Neurochem. 104, 21-37.
-
(2008)
J. Neurochem.
, vol.104
, pp. 21-37
-
-
Ambjorn, M.1
Asmussen, J.W.2
Lindstam, M.3
Gotfryd, K.4
Jacobsen, C.5
Kiselyov, V.V.6
Moestrup, S.K.7
Penkowa, M.8
Bock, E.9
Berezin, V.10
-
30
-
-
47249146602
-
Redefining the role of metallothionein within the injured brain: Extracellular metallothioneins play an important role in the astrocyte-neuron response to injury
-
Chung, R. S., Penkowa, M., Dittmann, J., King, C. E., Bartlett, C., Asmussen, J. W., Hidalgo, J., Carrasco, J., Leung, Y. K., Walker, A. K., Fung, S. J., Dunlop, S. A., Fitzgerald, M., Beazley, L. D., Chuah, M. I., Vickers, J. C., and West, A. K. (2008) Redefining the role of metallothionein within the injured brain: extracellular metallothioneins play an important role in the astrocyte-neuron response to injury. J. Biol. Chem. 283, 15349-15358.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15349-15358
-
-
Chung, R.S.1
Penkowa, M.2
Dittmann, J.3
King, C.E.4
Bartlett, C.5
Asmussen, J.W.6
Hidalgo, J.7
Carrasco, J.8
Leung, Y.K.9
Walker, A.K.10
Fung, S.J.11
Dunlop, S.A.12
Fitzgerald, M.13
Beazley, L.D.14
Chuah, M.I.15
Vickers, J.C.16
West, A.K.17
-
31
-
-
0037022717
-
Metallothionein 1+2 protect the CNS during neuroglial degeneration induced by 6-aminonicotinamide
-
Penkowa, M., Giralt, M., Camats, J., and Hidalgo, J. (2002) Metallothionein 1+2 protect the CNS during neuroglial degeneration induced by 6-aminonicotinamide. J. Comp. Neurol. 444, 174-189.
-
(2002)
J. Comp. Neurol.
, vol.444
, pp. 174-189
-
-
Penkowa, M.1
Giralt, M.2
Camats, J.3
Hidalgo, J.4
-
32
-
-
0033662509
-
Metallothionein I+II expression and their role in experimental autoimmune encephalomyelitis
-
Penkowa, M. and Hidalgo, J. (2000) Metallothionein I+II expression and their role in experimental autoimmune encephalomyelitis. Glia. 32, 247-263.
-
(2000)
Glia.
, vol.32
, pp. 247-263
-
-
Penkowa, M.1
Hidalgo, J.2
-
33
-
-
0037996720
-
Metallothionein- IIA promotes initial neurite elongation and postinjury reactive neurite growth and facilitates healing after focal cortical brain injury
-
Chung, R. S., Vickers, J. C., Chuah, M. I., and West, A. K. (2003) Metallothionein- IIA promotes initial neurite elongation and postinjury reactive neurite growth and facilitates healing after focal cortical brain injury. J. Neurosci. 23, 3336-3342.
-
(2003)
J. Neurosci.
, vol.23
, pp. 3336-3342
-
-
Chung, R.S.1
Vickers, J.C.2
Chuah, M.I.3
West, A.K.4
-
34
-
-
0034952985
-
Metallothionein treatment reduces proinflammatory cytokines IL-6 and TNF-alpha and apoptotic cell death during experimental autoimmune encephalomyelitis (EAE)
-
Penkowa, M. and Hidalgo, J. (2001) Metallothionein treatment reduces proinflammatory cytokines IL-6 and TNF-alpha and apoptotic cell death during experimental autoimmune encephalomyelitis (EAE). Exp. Neurol. 170, 1-14.
-
(2001)
Exp. Neurol.
, vol.170
, pp. 1-14
-
-
Penkowa, M.1
Hidalgo, J.2
-
35
-
-
0035479008
-
Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis
-
Penkowa, M., Espejo, C., Martinez-Caceres, E. M., Poulsen, C. B., Montalban, X., and Hidalgo, J. (2001) Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis. J. Neuroimmunol. 119, 248-260.
-
(2001)
J. Neuroimmunol.
, vol.119
, pp. 248-260
-
-
Penkowa, M.1
Espejo, C.2
Martinez-Caceres, E.M.3
Poulsen, C.B.4
Montalban, X.5
Hidalgo, J.6
-
36
-
-
0034633768
-
Defective T cell fas function in patients with multiple sclerosis
-
Comi, C., Leone, M., Bonissoni, S., DeFranco, S., Bottarel, F., Mezzatesta, C., Chiocchetti, A., Perla, F., Monaco, F., and Dianzani, U. (2000) Defective T cell fas function in patients with multiple sclerosis. Neurology 55, 921-927.
-
(2000)
Neurology
, vol.55
, pp. 921-927
-
-
Comi, C.1
Leone, M.2
Bonissoni, S.3
Defranco, S.4
Bottarel, F.5
Mezzatesta, C.6
Chiocchetti, A.7
Perla, F.8
Monaco, F.9
Dianzani, U.10
-
37
-
-
0034633769
-
Apoptosis mediators fasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS
-
Huang, W. X., Huang, M. P., Gomes, M. A., and Hillert, J. (2000) Apoptosis mediators fasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS. Neurology 55, 928-934.
-
(2000)
Neurology
, vol.55
, pp. 928-934
-
-
Huang, W.X.1
Huang, M.P.2
Gomes, M.A.3
Hillert, J.4
-
38
-
-
0034633711
-
Fas(t) track to apoptosis in MS: TNF receptors may suppress or potentiate CNS demyelination
-
Segal, B. M. and Cross, A. H. (2000) Fas(t) track to apoptosis in MS: TNF receptors may suppress or potentiate CNS demyelination. Neurology 55, 906-907.
-
(2000)
Neurology
, vol.55
, pp. 906-907
-
-
Segal, B.M.1
Cross, A.H.2
-
39
-
-
32244433433
-
Metallothionein and liver cell regeneration
-
Cherian, M. G. and Kang, Y. J. (2006) Metallothionein and liver cell regeneration. Exp. Biol. Med. (Maywood.) 231, 138-144.
-
(2006)
Exp. Biol. Med. (Maywood.)
, vol.231
, pp. 138-144
-
-
Cherian, M.G.1
Kang, Y.J.2
-
40
-
-
0027955113
-
Targeted disruption of metallothionein i and II genes increases sensitivity to cadmium
-
Masters, B. A., Kelly, E. J., Quaife, C. J., Brinster, R. L., and Palmiter, R. D. (1994) Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc. Natl. Acad. Sci. USA 91, 584-588.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 584-588
-
-
Masters, B.A.1
Kelly, E.J.2
Quaife, C.J.3
Brinster, R.L.4
Palmiter, R.D.5
-
41
-
-
34848813494
-
Metallothionein-IIA promotes neurite growth via the megalin receptor
-
Fitzgerald, M., Nairn, P., Bartlett, C. A., Chung, R. S., West, A. K., and Beazley, L. D. (2007) Metallothionein-IIA promotes neurite growth via the megalin receptor. Exp. Brain Res. 183, 171-180.
-
(2007)
Exp. Brain Res.
, vol.183
, pp. 171-180
-
-
Fitzgerald, M.1
Nairn, P.2
Bartlett, C.A.3
Chung, R.S.4
West, A.K.5
Beazley, L.D.6
-
42
-
-
0035006545
-
Megalin and cubilin: Synergistic endocytic receptors in renal proximal tubule
-
Christensen, E. I. and Birn, H. (2001) Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule. Am. J. Physiol. Renal. Physiol. 280, F562-F573.
-
(2001)
Am. J. Physiol. Renal. Physiol.
, vol.280
-
-
Christensen, E.I.1
Birn, H.2
-
43
-
-
84984766757
-
Megalin and cubilin: Multifunctional endocytic receptors
-
Christensen, E. I. and Birn, H. (2002) Megalin and cubilin: multifunctional endocytic receptors. Nat. Rev. Mol. Cell Biol. 3, 256-266.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 256-266
-
-
Christensen, E.I.1
Birn, H.2
-
44
-
-
0026731852
-
Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptorrelated protein in human tissues
-
Moestrup, S. K., Gliemann, J., and Pallesen, G. (1992) Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptorrelated protein in human tissues. Cell. Tissue Res. 269, 375-382.
-
(1992)
Cell. Tissue Res.
, vol.269
, pp. 375-382
-
-
Moestrup, S.K.1
Gliemann, J.2
Pallesen, G.3
-
45
-
-
0028324029
-
Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP)
-
Zheng, G., Bachinsky, D. R., Stamenkovic, I., Strickland, D. K., Brown, D., Andres, G., and McCluskey, R. T. (1994) Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP). J. Histochem. Cytochem. 42, 531-542.
-
(1994)
J. Histochem. Cytochem.
, vol.42
, pp. 531-542
-
-
Zheng, G.1
Bachinsky, D.R.2
Stamenkovic, I.3
Strickland, D.K.4
Brown, D.5
Andres, G.6
McCluskey, R.T.7
-
46
-
-
33751104453
-
The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: Possible implications in peripheral nerve injury
-
Campana, W. M., Li, X., Dragojlovic, N., Janes, J., Gaultier, A., and Gonias, S. L. (2006) The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: possible implications in peripheral nerve injury. J. Neurosci. 26, 11197-11207.
-
(2006)
J. Neurosci.
, vol.26
, pp. 11197-11207
-
-
Campana, W.M.1
Li, X.2
Dragojlovic, N.3
Janes, J.4
Gaultier, A.5
Gonias, S.L.6
-
47
-
-
0030896993
-
Endocytic trafficking of megalin/RAP complexes: Dissociation of the complexes in late endosomes
-
Czekay, R. P., Orlando, R. A., Woodward, L., Lundstrom, M., and Farquhar, M. G. (1997) Endocytic trafficking of megalin/RAP complexes: dissociation of the complexes in late endosomes. Mol. Biol. Cell 8, 517-532.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 517-532
-
-
Czekay, R.P.1
Orlando, R.A.2
Woodward, L.3
Lundstrom, M.4
Farquhar, M.G.5
-
48
-
-
33747052036
-
The role of megalin (LRP-2/ Gp330) during development
-
Fisher, C. E. and Howie, S. E. (2006) The role of megalin (LRP-2/ Gp330) during development. Dev. Biol. 296, 279-297.
-
(2006)
Dev. Biol.
, vol.296
, pp. 279-297
-
-
Fisher, C.E.1
Howie, S.E.2
-
49
-
-
33749427563
-
Involvement of oxidative stress in the synthesis of metallothionein induced by mitochondrial inhibitors
-
Futakawa, N., Kondoh, M., Ueda, S., Higashimoto, M., Takiguchi, M., Suzuki, S., and Sato, M. (2006) Involvement of oxidative stress in the synthesis of metallothionein induced by mitochondrial inhibitors. Biol. Pharm. Bull. 29, 2016-2020.
-
(2006)
Biol. Pharm. Bull.
, vol.29
, pp. 2016-2020
-
-
Futakawa, N.1
Kondoh, M.2
Ueda, S.3
Higashimoto, M.4
Takiguchi, M.5
Suzuki, S.6
Sato, M.7
-
50
-
-
4344639738
-
Metallothionein expression in human neoplasia
-
Theocharis, S. E., Margeli, A. P., Klijanienko, J. T., and Kouraklis, G. P. (2004) Metallothionein expression in human neoplasia. Histopathology 45, 103-118.
-
(2004)
Histopathology
, vol.45
, pp. 103-118
-
-
Theocharis, S.E.1
Margeli, A.P.2
Klijanienko, J.T.3
Kouraklis, G.P.4
-
51
-
-
0029948054
-
A murine model of Menkes disease reveals a physiological function of metallothionein
-
Kelly, E. J. and Palmiter, R. D. (1996) A murine model of Menkes disease reveals a physiological function of metallothionein. Nat. Genet. 13, 219-222.
-
(1996)
Nat. Genet.
, vol.13
, pp. 219-222
-
-
Kelly, E.J.1
Palmiter, R.D.2
-
52
-
-
0029987684
-
Metallothionein i and II protect against zinc deficiency and zinc toxicity in mice
-
Kelly, E. J., Quaife, C. J., Froelick, G. J., and Palmiter, R. D. (1996) Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice. J. Nutr. 126, 1782-1790.
-
(1996)
J. Nutr.
, vol.126
, pp. 1782-1790
-
-
Kelly, E.J.1
Quaife, C.J.2
Froelick, G.J.3
Palmiter, R.D.4
-
53
-
-
0030799592
-
Enhanced apoptosis in metallothionein null cells
-
Kondo, Y., Rusnak, J. M., Hoyt, D. G., Settineri, C. E., Pitt, B. R., and Lazo, J. S. (1997) Enhanced apoptosis in metallothionein null cells. Mol. Pharmacol. 52, 195-201.
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 195-201
-
-
Kondo, Y.1
Rusnak, J.M.2
Hoyt, D.G.3
Settineri, C.E.4
Pitt, B.R.5
Lazo, J.S.6
-
54
-
-
0027204069
-
Targeting and germ-line transmission of a null mutation at the metallothionein i and II loci in mouse
-
Michalska, A. E. and Choo, K. H. (1993) Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc. Natl. Acad. Sci. USA 90, 8088-8092.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8088-8092
-
-
Michalska, A.E.1
Choo, K.H.2
-
55
-
-
0037433953
-
Zinc-metallothionein protects from DNA damage induced by radiation better than glutathione and copperor cadmium-metallothioneins
-
Cai, L. and Cherian, M. G. (2003) Zinc-metallothionein protects from DNA damage induced by radiation better than glutathione and copperor cadmium-metallothioneins. Toxicol. Lett. 136, 193-198.
-
(2003)
Toxicol. Lett.
, vol.136
, pp. 193-198
-
-
Cai, L.1
Cherian, M.G.2
-
56
-
-
34848877207
-
Zinc, antioxidant systems and metallothionein in metal mediated-apoptosis: Biochemical and cytochemical aspects
-
Formigari, A., Irato, P., and Santon, A. (2007) Zinc, antioxidant systems and metallothionein in metal mediated-apoptosis: biochemical and cytochemical aspects. Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 146, 443-459.
-
(2007)
Comp. Biochem. Physiol. C. Toxicol. Pharmacol.
, vol.146
, pp. 443-459
-
-
Formigari, A.1
Irato, P.2
Santon, A.3
-
57
-
-
0024523351
-
Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein
-
Abel, J. and de Ruiter, N. (1989) Inhibition of hydroxyl-radical- generated DNA degradation by metallothionein. Toxicol. Lett. 47, 191-196.
-
(1989)
Toxicol. Lett.
, vol.47
, pp. 191-196
-
-
Abel, J.1
De Ruiter, N.2
-
58
-
-
0033517717
-
Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice
-
Ghoshal, K., Majumder, S., Li, Z., Bray, T. M., and Jacob, S. T. (1999) Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice. Biochem. Biophys. Res. Commun. 264, 735-742.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 735-742
-
-
Ghoshal, K.1
Majumder, S.2
Li, Z.3
Bray, T.M.4
Jacob, S.T.5
-
59
-
-
0027169905
-
Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase
-
Tamai, K. T., Gralla, E. B., Ellerby, L. M., Valentine, J. S., and Thiele, D. J. (1993) Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase. Proc. Natl. Acad. Sci. USA 90, 8013-8017.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8013-8017
-
-
Tamai, K.T.1
Gralla, E.B.2
Ellerby, L.M.3
Valentine, J.S.4
Thiele, D.J.5
-
60
-
-
0345280793
-
Metallothionein induction attenuates the effects of glutathione depletors in rat hepatocytes
-
Haidara, K., Moffatt, P., and Denizeau, F. (1999) Metallothionein induction attenuates the effects of glutathione depletors in rat hepatocytes. Toxicol. Sci. 49, 297-305.
-
(1999)
Toxicol. Sci.
, vol.49
, pp. 297-305
-
-
Haidara, K.1
Moffatt, P.2
Denizeau, F.3
-
61
-
-
0033990794
-
Regulation of metallothionein gene expression by oxidative stress and metal ions
-
Andrews, G. K. (2000) Regulation of metallothionein gene expression by oxidative stress and metal ions. Biochem. Pharmacol. 59, 95-104.
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 95-104
-
-
Andrews, G.K.1
-
62
-
-
0035929142
-
Specific induction of metallothionein synthesis by mitochondrial oxidative stress
-
Kondoh, M., Inoue, Y., Atagi, S., Futakawa, N., Higashimoto, M., and Sato, M. (2001) Specific induction of metallothionein synthesis by mitochondrial oxidative stress. Life Sci. 69, 2137-2146.
-
(2001)
Life Sci.
, vol.69
, pp. 2137-2146
-
-
Kondoh, M.1
Inoue, Y.2
Atagi, S.3
Futakawa, N.4
Higashimoto, M.5
Sato, M.6
-
63
-
-
33846260825
-
Metallothioneins i and II: Neuroprotective significance during CNS pathology
-
Stankovic, R. K., Chung, R. S., and Penkowa, M. (2007) Metallothioneins I and II: neuroprotective significance during CNS pathology. Int. J. Biochem. Cell Biol. 39, 484-489.
-
(2007)
Int. J. Biochem. Cell Biol.
, vol.39
, pp. 484-489
-
-
Stankovic, R.K.1
Chung, R.S.2
Penkowa, M.3
-
64
-
-
14144255777
-
Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures
-
Penkowa, M., Florit, S., Giralt, M., Quintana, A., Molinero, A., Carrasco, J., and Hidalgo, J. (2005) Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures. J. Neurosci. Res. 79, 522-534.
-
(2005)
J. Neurosci. Res.
, vol.79
, pp. 522-534
-
-
Penkowa, M.1
Florit, S.2
Giralt, M.3
Quintana, A.4
Molinero, A.5
Carrasco, J.6
Hidalgo, J.7
-
65
-
-
59649085915
-
The metallothionein/thionein system: An oxidoreductive metabolic zinc link
-
Bell, S. G. and Vallee, B. L. (2009) The metallothionein/thionein system: an oxidoreductive metabolic zinc link. Chembiochem. 10, 55-62.
-
(2009)
Chembiochem.
, vol.10
, pp. 55-62
-
-
Bell, S.G.1
Vallee, B.L.2
-
66
-
-
42049101604
-
Metallothionein redox biology in the cytoprotective and cytotoxic functions of zinc
-
Maret, W. (2008) Metallothionein redox biology in the cytoprotective and cytotoxic functions of zinc. Exp. Gerontol. 43, 363-369.
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 363-369
-
-
Maret, W.1
-
67
-
-
19744375548
-
Metallothionein transfers zinc to mitochondrial aconitase through a direct interaction in mouse hearts
-
Feng, W., Cai, J., Pierce, W. M., Franklin, R. B., Maret, W., Benz, F. W., and Kang, Y. J. (2005) Metallothionein transfers zinc to mitochondrial aconitase through a direct interaction in mouse hearts. Biochem. Biophys. Res. Commun. 332, 853-858.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.332
, pp. 853-858
-
-
Feng, W.1
Cai, J.2
Pierce, W.M.3
Franklin, R.B.4
Maret, W.5
Benz, F.W.6
Kang, Y.J.7
-
68
-
-
33745512245
-
Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues
-
Singh, K. K., Desouki, M. M., Franklin, R. B., and Costello, L. C. (2006) Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues. Mol. Cancer 5, 14.
-
(2006)
Mol. Cancer
, vol.5
, pp. 14
-
-
Singh, K.K.1
Desouki, M.M.2
Franklin, R.B.3
Costello, L.C.4
-
69
-
-
1642389890
-
Zinc and sulfur: A critical biological partnership
-
Maret, W. (2004) Zinc and sulfur: a critical biological partnership. Biochemistry 43, 3301-3309.
-
(2004)
Biochemistry
, vol.43
, pp. 3301-3309
-
-
Maret, W.1
-
70
-
-
33749641286
-
Metallothionein redox cycle and function
-
Kang, Y. J. (2006) Metallothionein redox cycle and function. Exp. Biol. Med. (Maywood) 231, 1459-1467.
-
(2006)
Exp. Biol. Med. (Maywood)
, vol.231
, pp. 1459-1467
-
-
Kang, Y.J.1
-
71
-
-
0034058549
-
The function of zinc metallothionein: A link between cellular zinc and redox state
-
Maret, W. (2000) The function of zinc metallothionein: a link between cellular zinc and redox state. J Nutr., 130, 1455S-1458S.
-
(2000)
J Nutr.
, vol.130
-
-
Maret, W.1
-
72
-
-
0029063792
-
Metallothionein/disulfide interactions, oxidative stress, and the mobilization of cellular zinc
-
Maret, W. (1995) Metallothionein/disulfide interactions, oxidative stress, and the mobilization of cellular zinc. Neurochem. Int. 27, 111-117.
-
(1995)
Neurochem. Int.
, vol.27
, pp. 111-117
-
-
Maret, W.1
-
73
-
-
33749513188
-
Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy
-
Cai, L., Wang, Y., Zhou, G., Chen, T., Song, Y., Li, X., and Kang, Y. J. (2006) Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy. J. Am. Coll. Cardiol. 48, 1688-1697.
-
(2006)
J. Am. Coll. Cardiol.
, vol.48
, pp. 1688-1697
-
-
Cai, L.1
Wang, Y.2
Zhou, G.3
Chen, T.4
Song, Y.5
Li, X.6
Kang, Y.J.7
-
74
-
-
36649022437
-
Changes in the vesicular zinc pattern following traumatic brain injury
-
Doering, P., Danscher, G., Larsen, A., Bruhn, M., Sondergaard, C., and Stoltenberg, M. (2007) Changes in the vesicular zinc pattern following traumatic brain injury. Neuroscience 150, 93-103.
-
(2007)
Neuroscience
, vol.150
, pp. 93-103
-
-
Doering, P.1
Danscher, G.2
Larsen, A.3
Bruhn, M.4
Sondergaard, C.5
Stoltenberg, M.6
-
75
-
-
18044397492
-
Zinc pyrithione induces apoptosis and increases expression of Bim
-
Mann, J. J. and Fraker, P. J. (2005) Zinc pyrithione induces apoptosis and increases expression of Bim. Apoptosis 10, 369-379.
-
(2005)
Apoptosis
, vol.10
, pp. 369-379
-
-
Mann, J.J.1
Fraker, P.J.2
-
76
-
-
0036143133
-
Ribozyme-mediated downregulation of human metallothionein II(a) induces apoptosis in human prostate and ovarian cancer cell lines
-
Tekur, S. and Ho, S. M. (2002) Ribozyme-mediated downregulation of human metallothionein II(a) induces apoptosis in human prostate and ovarian cancer cell lines. Mol. Carcinog. 33, 44-55.
-
(2002)
Mol. Carcinog.
, vol.33
, pp. 44-55
-
-
Tekur, S.1
Ho, S.M.2
-
77
-
-
0034859507
-
Zinc binding and redox control of p53 structure and function
-
Hainaut, P. and Mann, K. (2001) Zinc binding and redox control of p53 structure and function. Antioxid. Redox. Signal. 3, 611-623.
-
(2001)
Antioxid. Redox. Signal.
, vol.3
, pp. 611-623
-
-
Hainaut, P.1
Mann, K.2
-
78
-
-
0034597536
-
Metalloregulation of the tumor suppressor protein p53: Zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells
-
Meplan, C., Richard, M. J., and Hainaut, P. (2000) Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells. Oncogene 19, 5227-5236.
-
(2000)
Oncogene
, vol.19
, pp. 5227-5236
-
-
Meplan, C.1
Richard, M.J.2
Hainaut, P.3
-
79
-
-
32344433407
-
Interaction of metallothionein with tumor suppressor p53 protein
-
Ostrakhovitch, E. A., Olsson, P. E., Jiang, S., and Cherian, M. G. (2006) Interaction of metallothionein with tumor suppressor p53 protein. FEBS Lett. 580, 1235-1238.
-
(2006)
FEBS Lett.
, vol.580
, pp. 1235-1238
-
-
Ostrakhovitch, E.A.1
Olsson, P.E.2
Jiang, S.3
Cherian, M.G.4
-
80
-
-
36849074146
-
P53 mediated regulation of metallothionein transcription in breast cancer cells
-
Ostrakhovitch, E. A., Olsson, P. E., Hofsten von, J., and Cherian, M. G. (2007) P53 mediated regulation of metallothionein transcription in breast cancer cells. J. Cell Biochem. 102, 1571-1583.
-
(2007)
J. Cell Biochem.
, vol.102
, pp. 1571-1583
-
-
Ostrakhovitch, E.A.1
Olsson, P.E.2
Von, H.J.3
Cherian, M.G.4
-
81
-
-
0035696441
-
The duality of the inflammatory response to traumatic brain injury
-
Lenzlinger, P. M., Morganti-Kossmann, M. C., Laurer, H. L., and McIntosh, T. K. (2001) The duality of the inflammatory response to traumatic brain injury. Mol. Neurobiol. 24, 169-181.
-
(2001)
Mol. Neurobiol.
, vol.24
, pp. 169-181
-
-
Lenzlinger, P.M.1
Morganti-Kossmann, M.C.2
Laurer, H.L.3
McIntosh, T.K.4
-
82
-
-
30444459031
-
The role of inflammation in CNS injury and disease
-
Lucas, S. M., Rothwell, N. J., and Gibson, R. M. (2006) The role of inflammation in CNS injury and disease. Br. J. Pharmacol. 147 (Suppl 1), S232-S240.
-
(2006)
Br. J. Pharmacol.
, vol.147
, Issue.SUPPL. 1
-
-
Lucas, S.M.1
Rothwell, N.J.2
Gibson, R.M.3
-
83
-
-
51349134916
-
Astrocytes in multiple sclerosis: A product of their environment
-
Nair, A., Frederick, T. J., and Miller, S. D. (2008) Astrocytes in multiple sclerosis: a product of their environment. Cell. Mol. Life Sci. 65, 2702-2720.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 2702-2720
-
-
Nair, A.1
Frederick, T.J.2
Miller, S.D.3
-
84
-
-
25144440471
-
Reactive astrocytes in neural repair and protection
-
Sofroniew, M. V. (2005) Reactive astrocytes in neural repair and protection. Neuroscientist 11, 400-407.
-
(2005)
Neuroscientist
, vol.11
, pp. 400-407
-
-
Sofroniew, M.V.1
-
85
-
-
34247134579
-
Molecular mechanisms of astrogliosis: New approaches with mouse genetics
-
Correa-Cerro, L. S. and Mandell, J. W. (2007) Molecular mechanisms of astrogliosis: new approaches with mouse genetics. J. Neuropathol. Exp. Neurol. 66, 169-176.
-
(2007)
J. Neuropathol. Exp. Neurol.
, vol.66
, pp. 169-176
-
-
Correa-Cerro, L.S.1
Mandell, J.W.2
-
86
-
-
33644847478
-
Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways
-
Soto, I., Rosenthal, J. J., Blagburn, J. M., and Blanco, R. E. (2006) Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways. J. Neurochem. 96, 82-96.
-
(2006)
J. Neurochem.
, vol.96
, pp. 82-96
-
-
Soto, I.1
Rosenthal, J.J.2
Blagburn, J.M.3
Blanco, R.E.4
-
87
-
-
39149098789
-
Antidepressants induce acute CREB phosphorylation and CRE-mediated gene expression in glial cells: A possible contribution to GDNF production
-
Hisaoka, K., Maeda, N., Tsuchioka, M., and Takebayashi, M. (2008) Antidepressants induce acute CREB phosphorylation and CRE-mediated gene expression in glial cells: a possible contribution to GDNF production. Brain Res. 1196, 53-58.
-
(2008)
Brain Res.
, vol.1196
, pp. 53-58
-
-
Hisaoka, K.1
Maeda, N.2
Tsuchioka, M.3
Takebayashi, M.4
-
88
-
-
27144544752
-
Prostaglandin E2 enhances neurotrophin-4 production via EP3 receptor in human keratinocytes
-
Kanda, N., Koike, S., and Watanabe, S. (2005) Prostaglandin E2 enhances neurotrophin-4 production via EP3 receptor in human keratinocytes. J. Pharmacol. Exp. Ther. 315, 796-804.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.315
, pp. 796-804
-
-
Kanda, N.1
Koike, S.2
Watanabe, S.3
-
89
-
-
34547734912
-
Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells
-
Peng, C. H., Huang, C. N., Hsu, S. P. and Wang, C. J. (2007) Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells. Toxicology 238, 130-139.
-
(2007)
Toxicology
, vol.238
, pp. 130-139
-
-
Peng, C.H.1
Huang, C.N.2
Hsu, S.P.3
Wang, C.J.4
-
90
-
-
34147195051
-
Induction of transforming growth factorbeta1 by basic fibroblast growth factor in rat C6 glioma cells and astrocytes is mediated by MEK/ERK signaling and AP-1 activation
-
Dhandapani, K. M., Khan, M. M., Wade, F. M., Wakade, C., Mahesh, V. B., and Brann, D. W. (2007) Induction of transforming growth factorbeta1 by basic fibroblast growth factor in rat C6 glioma cells and astrocytes is mediated by MEK/ERK signaling and AP-1 activation, J. Neurosci. Res., 85, 1033-1045.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 1033-1045
-
-
Dhandapani, K.M.1
Khan, M.M.2
Wade, F.M.3
Wakade, C.4
Mahesh, V.B.5
Brann, D.W.6
-
91
-
-
0036241334
-
Induction of VEGF gene expression by retinoic acid through Sp1-binding sites in retinoblastoma Y79 cells
-
Akiyama, H., Tanaka, T., Maeno, T., Kanai, H., Kimura, Y., Kishi, S., and Kurabayashi, M. (2002) Induction of VEGF gene expression by retinoic acid through Sp1-binding sites in retinoblastoma Y79 cells. Invest. Ophthalmol. Vis. Sci. 43, 1367-1374.
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 1367-1374
-
-
Akiyama, H.1
Tanaka, T.2
Maeno, T.3
Kanai, H.4
Kimura, Y.5
Kishi, S.6
Kurabayashi, M.7
-
92
-
-
0033739097
-
Induction of VEGF gene transcription by IL-1 beta is mediated through stress-activated MAP kinases and Sp1 sites in cardiac myocytes
-
Tanaka, T., Kanai, H., Sekiguchi, K., Aihara, Y., Yokoyama, T., Arai, M., Kanda, T., Nagai, R., and Kurabayashi, M. (2000) Induction of VEGF gene transcription by IL-1 beta is mediated through stress-activated MAP kinases and Sp1 sites in cardiac myocytes. J. Mol. Cell Cardiol. 32, 1955-1967.
-
(2000)
J. Mol. Cell Cardiol.
, vol.32
, pp. 1955-1967
-
-
Tanaka, T.1
Kanai, H.2
Sekiguchi, K.3
Aihara, Y.4
Yokoyama, T.5
Arai, M.6
Kanda, T.7
Nagai, R.8
Kurabayashi, M.9
-
93
-
-
0034862877
-
Genes for neurotrophic factors and their receptors: Structure and regulation
-
Metsis, M. (2001) Genes for neurotrophic factors and their receptors: structure and regulation. Cell Mol. Life Sci. 58, 1014-1020.
-
(2001)
Cell Mol. Life Sci.
, vol.58
, pp. 1014-1020
-
-
Metsis, M.1
-
94
-
-
0032704219
-
The neurotrophins act synergistically with LIF and members of the TGF-beta superfamily to promote the survival of spiral ganglia neurons in vitro
-
Marzella, P. L., Gillespie, L. N., Clark, G. M., Bartlett, P. F., and Kilpatrick, T. J. (1999) The neurotrophins act synergistically with LIF and members of the TGF-beta superfamily to promote the survival of spiral ganglia neurons in vitro. Hear Res. 138, 73-80.
-
(1999)
Hear Res.
, vol.138
, pp. 73-80
-
-
Marzella, P.L.1
Gillespie, L.N.2
Clark, G.M.3
Bartlett, P.F.4
Kilpatrick, T.J.5
-
95
-
-
33846186883
-
Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation
-
Xiao, Z., Kong, Y., Yang, S., Li, M., Wen, J., and Li, L. (2007) Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation. Cell Res. 17, 73-79.
-
(2007)
Cell Res.
, vol.17
, pp. 73-79
-
-
Xiao, Z.1
Kong, Y.2
Yang, S.3
Li, M.4
Wen, J.5
Li, L.6
-
96
-
-
0032498164
-
Synergy between TGF-beta 3 and NT-3 to promote the survival of spiral ganglia neurones in vitro
-
Marzella, P. L., Clark, G. M., Shepherd, R. K., Bartlett, P. F., and Kilpatrick, T. J. (1998) Synergy between TGF-beta 3 and NT-3 to promote the survival of spiral ganglia neurones in vitro. Neurosci. Lett. 240, 77-80.
-
(1998)
Neurosci. Lett.
, vol.240
, pp. 77-80
-
-
Marzella, P.L.1
Clark, G.M.2
Shepherd, R.K.3
Bartlett, P.F.4
Kilpatrick, T.J.5
-
97
-
-
0031794123
-
TGF-beta regulates the survival of ciliary ganglionic neurons synergistically with ciliary neurotrophic factor and neurotrophins
-
Krieglstein, K., Farkas, L., and Unsicker, K. (1998) TGF-beta regulates the survival of ciliary ganglionic neurons synergistically with ciliary neurotrophic factor and neurotrophins. J. Neurobiol. 37, 563-572.
-
(1998)
J. Neurobiol.
, vol.37
, pp. 563-572
-
-
Krieglstein, K.1
Farkas, L.2
Unsicker, K.3
-
98
-
-
16444381597
-
Induction of human metallothionein 1G promoter by VEGF and heavy metals: Differential involvement of E2F and metal transcription factors
-
Joshi, B., Ordonez-Ercan, D., Dasgupta, P., and Chellappan, S. (2005) Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factors. Oncogene 24, 2204-2217.
-
(2005)
Oncogene
, vol.24
, pp. 2204-2217
-
-
Joshi, B.1
Ordonez-Ercan, D.2
Dasgupta, P.3
Chellappan, S.4
-
99
-
-
27744507452
-
Metallothionein 1 is a downstream target of vascular endothelial zinc finger 1 (VEZF1) in endothelial cells and participates in the regulation of angiogenesis
-
Miyashita, H., and Sato, Y. (2005) Metallothionein 1 is a downstream target of vascular endothelial zinc finger 1 (VEZF1) in endothelial cells and participates in the regulation of angiogenesis. Endothelium 12, 163-170.
-
(2005)
Endothelium
, vol.12
, pp. 163-170
-
-
Miyashita, H.1
Sato, Y.2
-
100
-
-
0036239958
-
Recent studies on metallothionein: Protection against toxicity of heavy metals and oxygen free radicals
-
Sato, M. and Kondoh, M. (2002) Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicals. Tohoku J. Exp. Med. 196, 9-22.
-
(2002)
Tohoku J. Exp. Med.
, vol.196
, pp. 9-22
-
-
Sato, M.1
Kondoh, M.2
-
101
-
-
0034641710
-
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
-
Brines, M. L., Ghezzi, P., Keenan, S., Agnello, D., de Lanerolle, N. C., Cerami, C., Itri, L. M., and Cerami, A. (2000) Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc. Natl. Acad. Sci. USA 97, 10526-10531.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10526-10531
-
-
Brines, M.L.1
Ghezzi, P.2
Keenan, S.3
Agnello, D.4
De Lanerolle, N.C.5
Cerami, C.6
Itri, L.M.7
Cerami, A.8
-
102
-
-
11244333356
-
New avenues of exploration for erythropoietin
-
Maiese, K., Li, F., and Chong, Z. Z. (2005) New avenues of exploration for erythropoietin. JAMA 293, 90-95.
-
(2005)
JAMA
, vol.293
, pp. 90-95
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
-
103
-
-
57049145362
-
Brain protection by erythropoietin: A manifold task
-
Rabie, T. and Marti, H. H. (2008) Brain protection by erythropoietin: a manifold task. Physiology (Bethesda) 23, 263-274.
-
(2008)
Physiology (Bethesda)
, vol.23
, pp. 263-274
-
-
Rabie, T.1
Marti, H.H.2
-
104
-
-
0141529770
-
Erythropoietin-induced metallothionein gene expression: Role in proliferation of K562 cells
-
Abdel-Mageed, A. B., Zhao, F., Rider, B. J., and Agrawal, K. C. (2003) Erythropoietin-induced metallothionein gene expression: role in proliferation of K562 cells. Exp. Biol. Med. (Maywood.) 228, 1033-1039.
-
(2003)
Exp. Biol. Med. (Maywood.)
, vol.228
, pp. 1033-1039
-
-
Abdel-Mageed, A.B.1
Zhao, F.2
Rider, B.J.3
Agrawal, K.C.4
-
105
-
-
34547683905
-
Neuroprotective effect of erythropoietin, and role of metallothionein-1 and -2, in permanent focal cerebral ischemia
-
Wakida, K., Shimazawa, M., Hozumi, I., Satoh, M., Nagase, H., Inuzuka, T., and Hara, H. (2007) Neuroprotective effect of erythropoietin, and role of metallothionein-1 and -2, in permanent focal cerebral ischemia. Neuroscience 148, 105-114.
-
(2007)
Neuroscience
, vol.148
, pp. 105-114
-
-
Wakida, K.1
Shimazawa, M.2
Hozumi, I.3
Satoh, M.4
Nagase, H.5
Inuzuka, T.6
Hara, H.7
-
106
-
-
48249108760
-
Therapeutic strategy of erythropoietin in neurological disorders
-
Liu, X. B., Wang, J. A., Yu, S. P., Keogh, C. L., and Wei, L. (2008) Therapeutic strategy of erythropoietin in neurological disorders. CNS Neurol. Disord. Drug. Targets 7, 227-234.
-
(2008)
CNS Neurol. Disord. Drug. Targets
, vol.7
, pp. 227-234
-
-
Liu, X.B.1
Wang, J.A.2
Yu, S.P.3
Keogh, C.L.4
Wei, L.5
-
107
-
-
44649152946
-
Metallothionein in the central nervous system: Roles in protection, regeneration and cognition
-
West, A. K., Hidalgo, J., Eddins, D., Levin, E. D., and Aschner, M. (2008) Metallothionein in the central nervous system: Roles in protection, regeneration and cognition. Neurotoxicology 29, 489-503.
-
(2008)
Neurotoxicology
, vol.29
, pp. 489-503
-
-
West, A.K.1
Hidalgo, J.2
Eddins, D.3
Levin, E.D.4
Aschner, M.5
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