Electrostatic compensation restores trafficking of the autosomal recessive retinitis pigmentosa E150k opsin mutant to the plasma membrane

Journal of Biological Chemistry

Volumn 285, Issue 38, 2010, Pages 29446-29456

  Pulagam, Lakshmi Padmavathi ^a   Palczewski, Krzysztof ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; CHROMOPHORES; GENE ENCODING; MEMBRANES; RESTORATION; VISION;

AUTOSOMAL DOMINANTS; DOUBLE MUTANTS; ELECTROSTATIC CALCULATIONS; ELECTROSTATIC INTERACTIONS; G PROTEIN COUPLED RECEPTORS; GOLGI APPARATUS; HEK293 CELLS; MEMBRANE TRAFFICKING; MOLECULAR MECHANISM; PARTIAL RESTORATION; PATHOPHYSIOLOGY; PLASMA MEMBRANES; POSITIVE CHARGES; RETINITIS PIGMENTOSA; ROD PHOTORECEPTORS; SPECTRAL CHARACTERISTICS; SURFACE ELECTROSTATICS; TRANS-GOLGI NETWORK; UV-VISIBLE SPECTRA; WILD-TYPE CONTROLS;

ELECTROSTATICS;

E150K OPSIN; MUTANT PROTEIN; OPSIN; RETINOID; RHODOPSIN; TRANSDUCIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CELL MEMBRANE; CELL STRAIN HEK293; CHROMATOPHORE; CONTROLLED STUDY; GENE MUTATION; GOLGI COMPLEX; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RETINITIS PIGMENTOSA; STATIC ELECTRICITY; SURFACE CHARGE; ULTRAVIOLET SPECTROSCOPY; WILD TYPE; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

CELL LINE; CELL MEMBRANE; HUMANS; IMMUNOHISTOCHEMISTRY; MODELS, BIOLOGICAL; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RETINITIS PIGMENTOSA; RHODOPSIN; STATIC ELECTRICITY;

EID: 77956518103     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.151407     Document Type: Article

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