-
1
-
-
33645535034
-
G protein-coupled receptor rhodopsin
-
Palczewski, K. (2006) G protein-coupled receptor rhodopsin. Ann. Rev. Biochem. 75, 743-767
-
(2006)
Ann. Rev. Biochem
, vol.75
, pp. 743-767
-
-
Palczewski, K.1
-
2
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Le Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E., Yamamoto, M., and Miyano, M. (2000) Crystal structure of rhodopsin: A G protein-coupled receptor. Science 289, 739-745
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
3
-
-
33750836895
-
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin
-
Salom, D., Lodowski, D. T., Stenkamp, R. E., Le Trong, I., Golczak, M., Jastrzebska, B., Harris, T., Ballesteros, J. A., and Palczewski, K. (2006) Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc. Natl. Acad. Sci. U. S. A. 103, 16123-16128
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 16123-16128
-
-
Salom, D.1
Lodowski, D.T.2
Stenkamp, R.E.3
Le Trong, I.4
Golczak, M.5
Jastrzebska, B.6
Harris, T.7
Ballesteros, J.A.8
Palczewski, K.9
-
4
-
-
0027132717
-
The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S
-
Noel, J. P., Hamm, H. E., and Sigler, P. B. (1993) The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S. Nature 366, 654-663
-
(1993)
Nature
, vol.366
, pp. 654-663
-
-
Noel, J.P.1
Hamm, H.E.2
Sigler, P.B.3
-
5
-
-
0032568021
-
X-ray crystal structure of arrestin from bovine rod outer segments
-
Granzin, J., Wilden, U., Choe, H. W., Labahn, J., Krafft, B., and Buldt, G. (1998) X-ray crystal structure of arrestin from bovine rod outer segments. Nature 391, 918-921
-
(1998)
Nature
, vol.391
, pp. 918-921
-
-
Granzin, J.1
Wilden, U.2
Choe, H.W.3
Labahn, J.4
Krafft, B.5
Buldt, G.6
-
6
-
-
0035931919
-
-
Slep, K. C., Kercher, M. A., He, W., Cowan, C. W., Wensel, T. G., and Sigler, P. B. (2001) Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A Nature 409, 1071-1077
-
Slep, K. C., Kercher, M. A., He, W., Cowan, C. W., Wensel, T. G., and Sigler, P. B. (2001) Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A Nature 409, 1071-1077
-
-
-
-
7
-
-
0642306488
-
Phototransduction: Crystal clear
-
Ridge, K D., Abdulaev, N. G., Sousa, M., and Palczewski, K (2003) Phototransduction: crystal clear. Trends Biochem. Sci. 28, 479-487
-
(2003)
Trends Biochem. Sci
, vol.28
, pp. 479-487
-
-
Ridge, K.D.1
Abdulaev, N.G.2
Sousa, M.3
Palczewski, K.4
-
8
-
-
34249884786
-
Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography
-
Nickell, S., Park, P. S., Baumeister, W., and Palczewski, K. (2007) Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography. J. Cell Biol. 177, 917-925
-
(2007)
J. Cell Biol
, vol.177
, pp. 917-925
-
-
Nickell, S.1
Park, P.S.2
Baumeister, W.3
Palczewski, K.4
-
9
-
-
0033680726
-
The gain of rod phototransduction: Reconciliation of biochemical and electrophysiological measurements
-
Leskov, I. B., Klenchin, V. A., Handy, J. W., Whitlock, G. G., Govardovskii, V. I., Bownds, M. D., Lamb, T. D., Pugh, E. N., Jr., and Arshavsky, V. Y. (2000) The gain of rod phototransduction: reconciliation of biochemical and electrophysiological measurements. Neuron 27, 525-537
-
(2000)
Neuron
, vol.27
, pp. 525-537
-
-
Leskov, I.B.1
Klenchin, V.A.2
Handy, J.W.3
Whitlock, G.G.4
Govardovskii, V.I.5
Bownds, M.D.6
Lamb, T.D.7
Pugh Jr., E.N.8
Arshavsky, V.Y.9
-
10
-
-
0029922635
-
Surface plasmon resonance spectroscopy studies of membrane proteins: Transducin binding and activation by rho-dopsin monitored in thin membrane films
-
Salamon, Z., Wang, Y., Soulages, J. L., Brown, M. F., and Tollin, G. (1996) Surface plasmon resonance spectroscopy studies of membrane proteins: transducin binding and activation by rho-dopsin monitored in thin membrane films. Biophys. J. 71, 283-294
-
(1996)
Biophys. J
, vol.71
, pp. 283-294
-
-
Salamon, Z.1
Wang, Y.2
Soulages, J.L.3
Brown, M.F.4
Tollin, G.5
-
11
-
-
0023141386
-
Kinetic studyon the equilibrium between membrane-bound and free photoreceptor G-protein
-
Schleicher, A., and Hofmann, K. P. (1987) Kinetic studyon the equilibrium between membrane-bound and free photoreceptor G-protein. J. Membr. Biol. 95, 271-281
-
(1987)
J. Membr. Biol
, vol.95
, pp. 271-281
-
-
Schleicher, A.1
Hofmann, K.P.2
-
12
-
-
0024427734
-
The transitory complex between photoexcited rhodopsin and transducin. Reciprocal interaction between the retinal site in rhodopsin and the nucleotide site in transducin
-
Bornancin, F., Pfister, C., and Chabre, M. (1989) The transitory complex between photoexcited rhodopsin and transducin. Reciprocal interaction between the retinal site in rhodopsin and the nucleotide site in transducin. Eur. J. Biochem./FEBS 184, 687-698
-
(1989)
Eur. J. Biochem./FEBS
, vol.184
, pp. 687-698
-
-
Bornancin, F.1
Pfister, C.2
Chabre, M.3
-
13
-
-
0038010379
-
Three cytoplasmic loops of rhodopsin interact with transducin
-
Konig, B., Arendt, A., McDowell, J. H., Kahlert, M., Hargrave, P. A., and Hofmann, K. P. (1989) Three cytoplasmic loops of rhodopsin interact with transducin. Proc. Natl. Acad. Sci. U. S. A. 86, 6878-6882
-
(1989)
Proc. Natl. Acad. Sci. U. S. A
, vol.86
, pp. 6878-6882
-
-
Konig, B.1
Arendt, A.2
McDowell, J.H.3
Kahlert, M.4
Hargrave, P.A.5
Hofmann, K.P.6
-
14
-
-
0035942102
-
Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin
-
Loewen, M. C., Klein-Seetharaman, J., Getmanova, E. V., Reeves, P. J., Schwalbe, H., and Khorana, H. G. (2001) Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin. Proc. Natl. Acad. Sci. U. S.A. 98, 4888-4892
-
(2001)
Proc. Natl. Acad. Sci. U. S.A
, vol.98
, pp. 4888-4892
-
-
Loewen, M.C.1
Klein-Seetharaman, J.2
Getmanova, E.V.3
Reeves, P.J.4
Schwalbe, H.5
Khorana, H.G.6
-
15
-
-
0035951805
-
Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin
-
Aris, L., Gilchrist, A., Rens-Domiano, S., Meyer, C., Schatz, P. J., Dratz, E. A., and Hamm, H. E. (2001) Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin. J. Biol. Chem. 276, 2333-2339
-
(2001)
J. Biol. Chem
, vol.276
, pp. 2333-2339
-
-
Aris, L.1
Gilchrist, A.2
Rens-Domiano, S.3
Meyer, C.4
Schatz, P.J.5
Dratz, E.A.6
Hamm, H.E.7
-
16
-
-
33750620488
-
Metarhodopsin-II stabilization by crosslinked Gtalpha C-terminal peptides and implications for the mechanism of GPCR-G protein coupling
-
Angel, T. E., Kraft, P. C., and Dratz, E. A. (2006) Metarhodopsin-II stabilization by crosslinked Gtalpha C-terminal peptides and implications for the mechanism of GPCR-G protein coupling. Vis. Res. 46, 4547-4555
-
(2006)
Vis. Res
, vol.46
, pp. 4547-4555
-
-
Angel, T.E.1
Kraft, P.C.2
Dratz, E.A.3
-
17
-
-
0028093624
-
A farnesylated domain in the G protein gamma subunit is a specific determinant of receptor coupling
-
Kisselev, O. G., Ermolaeva, M. V., and Gautam, N. (1994) A farnesylated domain in the G protein gamma subunit is a specific determinant of receptor coupling. J. Biol. Chem. 269, 21399-21402
-
(1994)
J. Biol. Chem
, vol.269
, pp. 21399-21402
-
-
Kisselev, O.G.1
Ermolaeva, M.V.2
Gautam, N.3
-
18
-
-
0037221946
-
Activation of G-protein Gα subunits by receptors through Gα-Gβ and Gβ-Gγ interactions
-
Cherfils, J., and Chabre, M. (2003) Activation of G-protein Gα subunits by receptors through Gα-Gβ and Gβ-Gγ interactions. Trends Biochem. Sci. 28, 13-17
-
(2003)
Trends Biochem. Sci
, vol.28
, pp. 13-17
-
-
Cherfils, J.1
Chabre, M.2
-
19
-
-
0037387322
-
Rhodopsin controls a conformational switch on the transducin gamma subunit
-
Kisselev, O. G., and Downs, M. A. (2003) Rhodopsin controls a conformational switch on the transducin gamma subunit. Structure (Camb.) 11, 367-373
-
(2003)
Structure (Camb.)
, vol.11
, pp. 367-373
-
-
Kisselev, O.G.1
Downs, M.A.2
-
20
-
-
2642588172
-
Sequence of interactions in receptor-G protein coupling
-
Herrmann, R., Heck, M., Henklein, P., Kleuss, C., Hofmann, K. P., and Ernst, O. P. (2004) Sequence of interactions in receptor-G protein coupling. J. Biol. Chem. 279, 24283-24290
-
(2004)
J. Biol. Chem
, vol.279
, pp. 24283-24290
-
-
Herrmann, R.1
Heck, M.2
Henklein, P.3
Kleuss, C.4
Hofmann, K.P.5
Ernst, O.P.6
-
21
-
-
3242773021
-
A concept for G protein activation by G protein-coupled receptor dimers: The transducin/rhodopsin interface
-
Filipek, S., Krzysko, K. A., Fotiadis, D., Liang, Y., Saperstein, D. A., Engel, A., and Palczewski, K. (2004) A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface. Photochem. Photobiol. Sci. 3, 628-638
-
(2004)
Photochem. Photobiol. Sci
, vol.3
, pp. 628-638
-
-
Filipek, S.1
Krzysko, K.A.2
Fotiadis, D.3
Liang, Y.4
Saperstein, D.A.5
Engel, A.6
Palczewski, K.7
-
22
-
-
0037426865
-
Atomic-force microscopy: Rhodopsin dimers in native disc membranes
-
Fotiadis, D., Liang, Y., Filipek, S., Saperstein, D. A., Engel, A., and Palczewski, K. (2003) Atomic-force microscopy: rhodopsin dimers in native disc membranes. Nature 421, 127-128
-
(2003)
Nature
, vol.421
, pp. 127-128
-
-
Fotiadis, D.1
Liang, Y.2
Filipek, S.3
Saperstein, D.A.4
Engel, A.5
Palczewski, K.6
-
23
-
-
0038159530
-
Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes
-
Liang, Y., Fotiadis, D., Filipek, S., Saperstein, D. A., Palczewski, K., and Engel, A. (2003) Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes. J. Biol. Chem. 278, 21655-21662
-
(2003)
J. Biol. Chem
, vol.278
, pp. 21655-21662
-
-
Liang, Y.1
Fotiadis, D.2
Filipek, S.3
Saperstein, D.A.4
Palczewski, K.5
Engel, A.6
-
24
-
-
0020009435
-
Preparation of antibodies to rhodopsin and the large protein of rod outer segments
-
Papermaster, D. S. (1982) Preparation of antibodies to rhodopsin and the large protein of rod outer segments. Methods Enzymol. 81, 240-246
-
(1982)
Methods Enzymol
, vol.81
, pp. 240-246
-
-
Papermaster, D.S.1
-
25
-
-
0023515308
-
Expression of a synthetic bovine rhodopsin gene in monkey kidney cells
-
Oprian, D. D., Molday, R. S., Kaufman, R.J., and Khorana, H. G. (1987) Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. Proc. Natl. Acad. Sci. U. S. A. 84, 8874-8878
-
(1987)
Proc. Natl. Acad. Sci. U. S. A
, vol.84
, pp. 8874-8878
-
-
Oprian, D.D.1
Molday, R.S.2
Kaufman, R.J.3
Khorana, H.G.4
-
26
-
-
10844243995
-
Functional characterization of rhodopsin monomers and dimers in detergents
-
Jastrzebska, B., Maeda, T., Zhu, L., Fotiadis, D., Filipek, S., Engel, A., Stenkamp, R. E., and Palczewski, K. (2004) Functional characterization of rhodopsin monomers and dimers in detergents. J. Biol. Chem. 279, 54663-54675
-
(2004)
J. Biol. Chem
, vol.279
, pp. 54663-54675
-
-
Jastrzebska, B.1
Maeda, T.2
Zhu, L.3
Fotiadis, D.4
Filipek, S.5
Engel, A.6
Stenkamp, R.E.7
Palczewski, K.8
-
27
-
-
0000073823
-
The molecular excitation of rhodopsin
-
Wald, G., and Brown, P. K. (1953) The molecular excitation of rhodopsin. J. Gen. Physiol. 37, 189-200
-
(1953)
J. Gen. Physiol
, vol.37
, pp. 189-200
-
-
Wald, G.1
Brown, P.K.2
-
29
-
-
0001740399
-
Tautomeric forms of metarhodopsin
-
Matthews, R. G., Hubbard, R., Brown, P. K., and Wald, G. (1963) Tautomeric forms of metarhodopsin. J. Gen. Physiol. 47, 215-240
-
(1963)
J. Gen. Physiol
, vol.47
, pp. 215-240
-
-
Matthews, R.G.1
Hubbard, R.2
Brown, P.K.3
Wald, G.4
-
30
-
-
1942468189
-
The G protein-coupled receptor rhodopsin in the native membrane
-
Fotiadis, D., Liang, Y., Filipek, S., Saperstein, D. A., Engel, A., and Palczewski, K. (2004) The G protein-coupled receptor rhodopsin in the native membrane. FEBS Lett. 564, 281-288
-
(2004)
FEBS Lett
, vol.564
, pp. 281-288
-
-
Fotiadis, D.1
Liang, Y.2
Filipek, S.3
Saperstein, D.A.4
Engel, A.5
Palczewski, K.6
-
31
-
-
33744965474
-
Functional and structural characterization of rhodopsin oligomers
-
Jastrzebska, B., Fotiadis, D., Jang, G. F., Stenkamp, R. E., Engel, A., and Palczewski, K. (2006) Functional and structural characterization of rhodopsin oligomers. J. Biol. Chem. 281, 11917-11922
-
(2006)
J. Biol. Chem
, vol.281
, pp. 11917-11922
-
-
Jastrzebska, B.1
Fotiadis, D.2
Jang, G.F.3
Stenkamp, R.E.4
Engel, A.5
Palczewski, K.6
-
32
-
-
0023062991
-
G proteins: Transducers of receptor-generated signals
-
Gilman, A. G. (1987) G proteins: transducers of receptor-generated signals. Ann. Rev. Biochem. 56, 615-649
-
(1987)
Ann. Rev. Biochem
, vol.56
, pp. 615-649
-
-
Gilman, A.G.1
-
33
-
-
0018901497
-
Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes
-
Kuhn, H. (1980) Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes. Nature 283, 587-589
-
(1980)
Nature
, vol.283
, pp. 587-589
-
-
Kuhn, H.1
-
34
-
-
0021233505
-
Characterization of transducin from bovine retinal rod outer segments. Mechanism and effects of cholera toxin-catalyzed ADP-ribosylation
-
Navon, S. E., and Fung, B. K. (1984) Characterization of transducin from bovine retinal rod outer segments. Mechanism and effects of cholera toxin-catalyzed ADP-ribosylation. J. Biol. Chem. 259, 6686-6693
-
(1984)
J. Biol. Chem
, vol.259
, pp. 6686-6693
-
-
Navon, S.E.1
Fung, B.K.2
-
35
-
-
0028138288
-
Rod outer segment retinol dehydrogenase: Substrate specificity and role in phototransduction
-
Palczewski, K., Jager, S., Buczylko, J., Crouch, R. K., Bredberg, D. L., Hofmann, K. P., Asson-Batres, M. A., and Saari, J. C. (1994) Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction. Biochemistry 33, 13741-13750
-
(1994)
Biochemistry
, vol.33
, pp. 13741-13750
-
-
Palczewski, K.1
Jager, S.2
Buczylko, J.3
Crouch, R.K.4
Bredberg, D.L.5
Hofmann, K.P.6
Asson-Batres, M.A.7
Saari, J.C.8
-
36
-
-
0029929261
-
Opsin/all- trans-retinal complex activates transducin by different mechanisms than photolyzed rhodopsin
-
Jager, S., Palczewski, K., and Hofmann, K. P. (1996) Opsin/all- trans-retinal complex activates transducin by different mechanisms than photolyzed rhodopsin. Biochemistry 35, 2901-2908
-
(1996)
Biochemistry
, vol.35
, pp. 2901-2908
-
-
Jager, S.1
Palczewski, K.2
Hofmann, K.P.3
-
37
-
-
0343081370
-
X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles
-
Okada, T., Le Trong, I., Fox, B. A., Behnke, C. A., Stenkamp, R. E., and Palczewski, K. (2000) X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles. J. Struct. Biol. 130, 73-80
-
(2000)
J. Struct. Biol
, vol.130
, pp. 73-80
-
-
Okada, T.1
Le Trong, I.2
Fox, B.A.3
Behnke, C.A.4
Stenkamp, R.E.5
Palczewski, K.6
-
38
-
-
36249009646
-
Opsin stability and folding: Modulation by phospholipid bicelles
-
McKibbin, C., Farmer, N. A., Jeans, C., Reeves, P. J., Khorana, H. G., Wallace, B. A., Edwards, P. C., Villa, C., and Booth, P. J. (2007) Opsin stability and folding: modulation by phospholipid bicelles. J. Mol. Biol. 374, 1319-1332
-
(2007)
J. Mol. Biol
, vol.374
, pp. 1319-1332
-
-
McKibbin, C.1
Farmer, N.A.2
Jeans, C.3
Reeves, P.J.4
Khorana, H.G.5
Wallace, B.A.6
Edwards, P.C.7
Villa, C.8
Booth, P.J.9
-
39
-
-
36248992965
-
Opsin stability and folding: The role of Cys185 and abnormal disulfide bond formation in the intradiscal domain
-
McKibbin, C., Toye, A. M., Reeves, P. J., Khorana, H. G., Edwards, P. C., Villa, C., and Booth, P. J. (2007) Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain. J. Mol. Biol. 374, 1309-1318
-
(2007)
J. Mol. Biol
, vol.374
, pp. 1309-1318
-
-
McKibbin, C.1
Toye, A.M.2
Reeves, P.J.3
Khorana, H.G.4
Edwards, P.C.5
Villa, C.6
Booth, P.J.7
-
40
-
-
0042591319
-
Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin
-
Schadel, S. A., Heck, M., Maretzki, D., Filipek, S., Teller, D. C., Palczewski, K., and Hofmann, K. P. (2003) Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin. J. Biol. Chem. 278, 24896-24903
-
(2003)
J. Biol. Chem
, vol.278
, pp. 24896-24903
-
-
Schadel, S.A.1
Heck, M.2
Maretzki, D.3
Filipek, S.4
Teller, D.C.5
Palczewski, K.6
Hofmann, K.P.7
-
41
-
-
0018858283
-
Dark isomerization of retinals in the presence of phosphatidylethanolamine
-
Groenendijk, G. W., Jacobs, C. W., Bonting, S. L., and Daemen, F. J. (1980) Dark isomerization of retinals in the presence of phosphatidylethanolamine. Eur. J. Biochem./FEBS 106, 119-128
-
(1980)
Eur. J. Biochem./FEBS
, vol.106
, pp. 119-128
-
-
Groenendijk, G.W.1
Jacobs, C.W.2
Bonting, S.L.3
Daemen, F.J.4
-
42
-
-
0024362631
-
Effect of carboxylic acid side chains on the absorption maximum of visual pigments
-
Zhukovsky, E. A., and Oprian, D. D. (1989) Effect of carboxylic acid side chains on the absorption maximum of visual pigments. Science 246, 928-930
-
(1989)
Science
, vol.246
, pp. 928-930
-
-
Zhukovsky, E.A.1
Oprian, D.D.2
-
43
-
-
38949112855
-
Galpha-subunits differentially alter the conformation and agonist affinity of kappa-opioid receptors
-
Yan, F., Mosier, P. D., Westkaemper, R. B., and Roth, B. L. (2008) Galpha-subunits differentially alter the conformation and agonist affinity of kappa-opioid receptors. Biochemistry 47, 1567-1578
-
(2008)
Biochemistry
, vol.47
, pp. 1567-1578
-
-
Yan, F.1
Mosier, P.D.2
Westkaemper, R.B.3
Roth, B.L.4
-
44
-
-
0032412196
-
Visual pigment: G-protein-coupled receptor for light signals
-
Shichida, Y., and Imai, H. (1998) Visual pigment: G-protein-coupled receptor for light signals. Cell. Mol. Life Sci. 54, 1299-1315
-
(1998)
Cell. Mol. Life Sci
, vol.54
, pp. 1299-1315
-
-
Shichida, Y.1
Imai, H.2
-
45
-
-
0034636820
-
G protein-coupled receptor activation: Analysis of a highly constrained, " straitjacketed" rhodopsin
-
Struthers, M., Yu, H., and Oprian, D. D. (2000) G protein-coupled receptor activation: analysis of a highly constrained, " straitjacketed" rhodopsin. Biochemistry 39, 7938-7942
-
(2000)
Biochemistry
, vol.39
, pp. 7938-7942
-
-
Struthers, M.1
Yu, H.2
Oprian, D.D.3
|