The SNARE Vti1a-β is localized to small synaptic vesicles and participates in a novel SNARE complex

Journal of Neuroscience

Volumn 20, Issue 15, 2000, Pages 5724-5732

  Antonin, Wolfram ^b   Riedel, Dietmar ^b   Von Mollard, Gabriele Fischer ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Clathrin coated vesicle; Endosome; Membrane traffic; Nerve terminal; SNARE; Synaptic vesicle; Vti1

Indexed keywords

CLATHRIN; N ETHYLMALEIMIDE; PROTEIN VTI 1A BETA; PROTEIN VTI 1B; SNARE PROTEIN; SYNAPTOBREVIN; UNCLASSIFIED DRUG;

ARTICLE; ENDOSOME; EXOCYTOSIS; EXPRESSED SEQUENCE TAG; MEMBRANE FUSION; MEMBRANE TRANSPORT; NERVE ENDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SYNAPSE VESICLE;

EID: 0034255152     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-15-05724.2000     Document Type: Article

References (55)

1. Seven novel mammalian SNARE proteins localize to distinct membrane compartments
2. VAMP-7 mediates vesicular transport from endosomes to lysosomes
3. High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism
4. A marker of early amacrine cell development in rat retina
5. Inhibition of transmitter release correlates with the proteolytic activity of tetanus toxin and botulinus toxin A in individual cultured synapses of Hirudo medicinalis
6. Synaptic vesicles immunoisolated from rat cerebral cortex contain high levels of glutamate
7. Reconstitution of synaptic vesicle biogenesis from PC12 cell membranes
8. Subcellular localization of tetanus neurotoxin-insensitive vesicle-associated membrane protein (VAMP)/VAMP7 in neuronal cells: Evidence for a novel membrane compartment
9. Synaptic vesicle endocytosis
10. Synaptic vesicles from by budding from tubular extensions of sorting endosomes in PC12 cells
11. Identification of a minimal core of the synaptic SNARE complex sufficient for reversible assembly and disassembly
12. Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs
13. Mixed and non-cognate SNARE complexes
14. A Human homolog can functionally replace the yeast v-SNARE Vti1p in two vesicle transport pathways
15. The Saccharomyces cerevisiae v-SNARE Vti1p is required for multiple membrane transport pathways to the vacuole
16. Localization of rab5 to synaptic vesicles identifies endosomal intermediate in synaptic recycling pathway
17. The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p
18. A targeting signal in VAMP regulating transport to synaptic vesicles
19. Differential extraction of proteins from paraformaldehyde-fixed cells: Lessons from synaptophysin and other membrane proteins
20. Synaptic vesicle biogenesis
21. The N-ethylmaleimide sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin
22. Two syntaxin homologues in the TGN/endosomal system in yeast
23. Synapsin I (protein I) a nerve terminal specific phosphoprotein. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation
24. Membrane fusion and exocytosis
25. A 38,000-dalton membrane protein (p38) present in synaptic vesicles
26. Characterization of a novel yeast SNARE protein implicated in Golgi retrograde traffic
27. Association of rab3A with synaptic vesicles at late stages of the secretory pathway
28. Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling
29. Endocytosis of synaptic vesicle membrane at the frog neuromuscular junction
30. Zinc-aldehyde fixation for light-microscopic immunocytochemistry of nervous tissues
31. Synaptic vesicles retain their identity through the endocytic cycle
32. Protease resistance of syntaxin.SNAP-25.VAMP complexes. Implications for assembly and structure
33. Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes
34. Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking
35. Synaptic NMDA receptor channels have a low open probability
36. Analysis of a yeast SNARE complex reveals remarkable similarity to the neuronal SNARE complex and a novel function for the C-terminus of the SNAP-25 homolog, Sec9
37. Mechanism of intracellular protein transport
38. Biogenesis of synaptic-like microvesicles in perforated PC12 cells
39. Neuroendocrine synaptic vesicles are formed in vitro by both clathrin-dependent and clathrin-independent pathways
40. The rab5 effector EEA1 interacts directly with syntaxin 6
41. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
42. SNAP receptors implicated in vesicle targeting and fusion
43. Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking
44. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution
45. The synaptic vesicle cycle: A single vesicle budding step involving clathrin and dynamin
46. Syntaxin 10: A member of the syntaxin family localized to the trans-Golgi network
47. Syntaxin 12, a member of the syntaxin family localized to the endosome
48. Three v-SNAREs and two t-SNAREs, present in a pentameric cis-SNARE complex on isolated vacuoles, are essential for homotypic fusion
49. Syntaxin 11 is associated with SNAP-23 on late endosomes and the trans-Golgi network
50. Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic
51. Human syntaxin7: A Pep12p/Vps6p homologue implicated in vesicle trafficking to lysosomes
52. A method for the quantitative recovery of proteins in dilute solutions in the presence of detergents and lipids
53. Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome
54. A 29-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (Vti1-rp2) implicated in protein trafficking in the secretory pathway
55. SNARE proteins are not selective. Implications for membrane fusion specificity