A novel doxycycline inducible autoregulatory plasmid which displays 'on'/'off' regulation suited to gene therapy applications

Gene Therapy

Volumn 7, Issue 24, 2000, Pages 2061-2070

  Gould, D J ^a   Berenstein, M ^b   Dreja, H ^a   Ledda, F ^b   Podhajcer, O L ^b   Chernajovsky, Y ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Autoregulatory; Gene therapy; Reverse tetracycline transactivator; RtTA

Indexed keywords

COMPLEMENT COMPONENT C3B RECEPTOR; DOXYCYCLINE; GREEN FLUORESCENT PROTEIN; HYGROMYCIN B; LUCIFERASE; PLASMID VECTOR; TETRACYCLINE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; AUTOREGULATION; CHRONIC DISEASE; CONTROLLED STUDY; EUKARYOTIC CELL; FIBROBLAST CULTURE; GENE CONTROL; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KINETICS; MOUSE; MULTIPLE SCLEROSIS; NEUROBLASTOMA CELL; NONHUMAN; ON OFF PHENOMENON; PLASMID; PRIORITY JOURNAL; REGULATORY MECHANISM; RELAPSE; REPORTER GENE; RETROVIRUS; RHEUMATOID ARTHRITIS; TRANSCRIPTION REGULATION;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL LINE; DOXYCYCLINE; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LUCIFERASES; LUMINESCENT PROTEINS; MICE; MICE, INBRED DBA; PLASMIDS; RECEPTORS, COMPLEMENT; RETROVIRIDAE; TRANSFECTION;

ANIMALIA; EUKARYOTA; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0034509652     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301354     Document Type: Article

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