Structure and function in rhodopsin: Correct folding and misfolding in point mutants at and in proximity to the site of the retinitis pigmentosa mutation Leu-125 → Arg in the transmembrane helix C

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 10, 1996, Pages 4560-4564

  Garriga, Pere ^a,b   Liu, Xun ^a   Khorana, H Gobind ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

Author keywords

11 cis retinal; Binding pocket; G protein coupled receptor; Intradiscal domain; Signal transduction

Indexed keywords

STAPHYLOCOCCUS PHAGE 187;

11 CIS RETINAL; GUANINE NUCLEOTIDE BINDING PROTEIN; RETINOID BINDING PROTEIN; RHODOPSIN; TRANSDUCIN;

AMINO ACID SUBSTITUTION; ARTICLE; AUTOSOMAL DOMINANT DISORDER; DISULFIDE BOND; GENE MUTATION; PRIORITY JOURNAL; PROTEIN FOLDING; RETINITIS PIGMENTOSA; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; BINDING SITES; CATTLE; CELL LINE; CONSERVED SEQUENCE; GENE EXPRESSION; GENES, DOMINANT; HUMANS; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RETINITIS PIGMENTOSA; RHODOPSIN; TRANSFECTION;

EID: 0029944275     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.10.4560     Document Type: Article

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