-
1
-
-
33846466508
-
Epidemiology of invasive candidiasis: A persistent public health problem
-
J
-
Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: a persistent public health problem [J]. Clin Microbiol Rev, 2007, 20: 133-163.
-
(2007)
Clin Microbiol Rev
, vol.20
, pp. 133-163
-
-
Pfaller, M.A.1
Diekema, D.J.2
-
2
-
-
3943093972
-
Nosocomial bloodstream infections in US hospitals: Analysis of 24,179 cases from a prospective nationwide surveillance study
-
J
-
Wisplinghoff H, Bischoff T, Tallent SM, et al. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study [J]. Clin Infect Dis, 2004, 39: 309-317.
-
(2004)
Clin Infect Dis
, vol.39
, pp. 309-317
-
-
Wisplinghoff, H.1
Bischoff, T.2
Tallent, S.M.3
-
3
-
-
0345489076
-
Ergosterol biosynthesis inhibitors become fungicidal when combined with calcineurin inhibitors against Candida albicans, Candida glabrata, and Candida krusei
-
J
-
Onyewu C, Blankenship JR, Del Poeta M, et al. Ergosterol biosynthesis inhibitors become fungicidal when combined with calcineurin inhibitors against Candida albicans, Candida glabrata, and Candida krusei [J]. Antimicrob Agents Chemother, 2003, 47: 956-964.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 956-964
-
-
Onyewu, C.1
Blankenship, J.R.2
Del Poeta, M.3
-
4
-
-
41149159789
-
Susceptibility of clinical isolates of Candida species to fluconazole and detection of Candida albicans ERG11 mutations
-
J
-
Xu YH, Chen LM, Li CY. Susceptibility of clinical isolates of Candida species to fluconazole and detection of Candida albicans ERG11 mutations [J]. J Antimicrob Chemother, 2008, 61: 798-804.
-
(2008)
J Antimicrob Chemother
, vol.61
, pp. 798-804
-
-
Xu, Y.H.1
Chen, L.M.2
Li, C.Y.3
-
5
-
-
0031054924
-
The mutation T315A in Candida albicans sterol 14-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity
-
J
-
Lamb DC, Kelly DE, Schunck WH, et al. The mutation T315A in Candida albicans sterol 14-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity [J]. J Biol Chem, 1997, 272: 5682-5688.
-
(1997)
J Biol Chem
, vol.272
, pp. 5682-5688
-
-
Lamb, D.C.1
Kelly, D.E.2
Schunck, W.H.3
-
6
-
-
0031938057
-
Amino acid substitutions in the cytochrome P-450 lanosterol 14α-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents
-
J
-
Sanglard D, Ischer F, Koymans L, et al. Amino acid substitutions in the cytochrome P-450 lanosterol 14α-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents [J]. Antimicrob Agents Chemother, 1998, 42: 241-253.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 241-253
-
-
Sanglard, D.1
Ischer, F.2
Koymans, L.3
-
7
-
-
0033986849
-
The R467K amino acid substitution in Candida albicans sterol 14alpha-demethylase causes drug resistance throush reduced affinity
-
J
-
Lamb DC, Kelly DE, White TC, et al. The R467K amino acid substitution in Candida albicans sterol 14alpha-demethylase causes drug resistance throush reduced affinity [J]. Antimicrob Agents Chemother, 2000, 44: 63-67.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 63-67
-
-
Lamb, D.C.1
Kelly, D.E.2
White, T.C.3
-
8
-
-
0035853108
-
Crystal structure of cytochrome P450 14 a-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors
-
J
-
Podust LM, Poulos TL, Waterman MR. Crystal structure of cytochrome P450 14 a-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors [J]. Proc Natl Acad Sci USA, 2001, 98: 3068-3073.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3068-3073
-
-
Podust, L.M.1
Poulos, T.L.2
Waterman, M.R.3
-
9
-
-
21044452931
-
Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): A live example showing the selection of altered P450 through interaction with environmental compounds
-
J
-
Kudo M, Ohi M, Aoyama Y, et al. Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental compounds [J]. J Biochem, 2005, 137: 625-632.
-
(2005)
J Biochem
, vol.137
, pp. 625-632
-
-
Kudo, M.1
Ohi, M.2
Aoyama, Y.3
-
10
-
-
47049101245
-
A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate
-
J
-
Dunkel N, Liu TT, Barker KS, et al. A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate [J]. Eukaryot Cell, 2008, 7: 1180-1190.
-
(2008)
Eukaryot Cell
, vol.7
, pp. 1180-1190
-
-
Dunkel, N.1
Liu, T.T.2
Barker, K.S.3
-
11
-
-
73849109145
-
An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans
-
J
-
Heilmann CJ, Schneider S, Barker KS, et al. An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans [J]. Antimicrob Agents Chemother, 2010, 54: 353-359.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 353-359
-
-
Heilmann, C.J.1
Schneider, S.2
Barker, K.S.3
-
12
-
-
57849086887
-
DNA microarray analysis of fluconazole resistance in a laboratory Candida albicans strain
-
J
-
Yan L, Zhang J, Li M, et al. DNA microarray analysis of fluconazole resistance in a laboratory Candida albicans strain [J]. Acta Biochim Biophys Sin, 2008, 40: 1048-1060.
-
(2008)
Acta Biochim Biophys Sin
, vol.40
, pp. 1048-1060
-
-
Yan, L.1
Zhang, J.2
Li, M.3
-
13
-
-
31944440019
-
Fluconazole treatment is effective against a Candida albicans erg3/erg3 mutant in vivo despite in vitro resistance
-
J
-
Miyazaki T, Miyazaki Y, Izumikawa K, et al. Fluconazole treatment is effective against a Candida albicans erg3/erg3 mutant in vivo despite in vitro resistance [J]. Antimicrob Agents Chemother, 2006, 50: 580-586.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 580-586
-
-
Miyazaki, T.1
Miyazaki, Y.2
Izumikawa, K.3
-
14
-
-
7444252872
-
Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase
-
J
-
Pierson CA, Jia N, Mo C, et al. Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase [J]. Med Mycol, 2004, 42: 461-473.
-
(2004)
Med Mycol
, vol.42
, pp. 461-473
-
-
Pierson, C.A.1
Jia, N.2
Mo, C.3
-
15
-
-
2142645082
-
Membrane sphingolipid-ergosterol interactions are important determinants of multidrug resistance in Candida albicans
-
J
-
Mukhopadhyay K, Prasad T, Saini P, et al. Membrane sphingolipid- ergosterol interactions are important determinants of multidrug resistance in Candida albicans [J]. Antimicrob Agents Chemother, 2004, 48: 1778-1787.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 1778-1787
-
-
Mukhopadhyay, K.1
Prasad, T.2
Saini, P.3
-
16
-
-
54249167145
-
ATP-binding-cassette transporters and fluconazole-resistance of clinical Candida albicans strains
-
J
-
Sun WW, Gao PH, Jiang YY, et al. ATP-binding-cassette transporters and fluconazole-resistance of clinical Candida albicans strains [J]. Acad J Second Mil Med Univ, 2008, 29: 1038-1041.
-
(2008)
Acad J Second Mil Med Univ
, vol.29
, pp. 1038-1041
-
-
Sun, W.W.1
Gao, P.H.2
Jiang, Y.Y.3
-
17
-
-
33751509420
-
Allelic variants of ABC drug transporter Cdr1p in clinical isolates of Candida albicans
-
J
-
Haque A, Rai V, Bahal BS, et al. Allelic variants of ABC drug transporter Cdr1p in clinical isolates of Candida albicans [J]. Biochem Biophys Res Commun, 2007, 352: 491-497.
-
(2007)
Biochem Biophys Res Commun
, vol.352
, pp. 491-497
-
-
Haque, A.1
Rai, V.2
Bahal, B.S.3
-
18
-
-
33748672708
-
Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2
-
J
-
Holmes AR, Tsao S, Ong SW, et al. Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2 [J]. Mol Microbiol, 2006, 62: 170-186.
-
(2006)
Mol Microbiol
, vol.62
, pp. 170-186
-
-
Holmes, A.R.1
Tsao, S.2
Ong, S.W.3
-
19
-
-
0347694571
-
Functional characterization of Candida albicans ABC transporter Cdrlp
-
J
-
Shukla S, Saini P, Smiriti, et al. Functional characterization of Candida albicans ABC transporter Cdrlp [J]. Eukaryot Cell, 2003, 2: 1361-1375.
-
(2003)
Eukaryot Cell
, vol.2
, pp. 1361-1375
-
-
Shukla, S.1
Saini, P.2
Smiriti3
-
20
-
-
3543108437
-
Substitution of threonine-1351 in the multidrug transporter Cdrlp of Candida albicans results in hypersusceptibility to antifungal agents and is essential for synergic effects of calcineurin inhibitor FK520
-
J
-
Shukla S, Ambudkar SV, Prasad R. Substitution of threonine-1351 in the multidrug transporter Cdrlp of Candida albicans results in hypersusceptibility to antifungal agents and is essential for synergic effects of calcineurin inhibitor FK520 [J]. J Antimicrob Chemother, 2004, 54: 38-45.
-
(2004)
J Antimicrob Chemother
, vol.54
, pp. 38-45
-
-
Shukla, S.1
Ambudkar, S.V.2
Prasad, R.3
-
21
-
-
33745183992
-
Drug susceptibilities of yeast cells are affected when expressing mutant Candida albicans drug resistance protein
-
J
-
Gao PH, Cao YB, Jia XM, et al. Drug susceptibilities of yeast cells are affected when expressing mutant Candida albicans drug resistance protein [J]. Int J Antimicrob Agents, 2006, 28: 69-74.
-
(2006)
Int J Antimicrob Agents
, vol.28
, pp. 69-74
-
-
Gao, P.H.1
Cao, Y.B.2
Jia, X.M.3
-
22
-
-
0042318833
-
Purification and characterization of N-terminal nucleotide-binding domain of an ABC drug transporter of Candida albicans: Uncommon cysteine 193 of Walker a is critical for ATP hydrolysis
-
J
-
Jha S, Karnani N, Dhar SK, et al. Purification and characterization of N-terminal nucleotide-binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis [J]. Biochemistry, 2003, 42: 10822-10832.
-
(2003)
Biochemistry
, vol.42
, pp. 10822-10832
-
-
Jha, S.1
Karnani, N.2
Dhar, S.K.3
-
23
-
-
0036829647
-
The "LSGGQ" motif in each nucleotide-domain of human P-glycoportein is adjacent to the opposing Walker A sequence
-
J
-
Loo TW, Bartlett MC, Clarke DM. The "LSGGQ" motif in each nucleotide-domain of human P-glycoportein is adjacent to the opposing Walker A sequence [J]. J Biol Chem, 2002, 277: 41303-41306.
-
(2002)
J Biol Chem
, vol.277
, pp. 41303-41306
-
-
Loo, T.W.1
Bartlett, M.C.2
Clarke, D.M.3
-
24
-
-
35348903338
-
Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates
-
J
-
Coste A, Selmecki A, Forche A, et al. Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates [J]. Eukaryot Cell, 2007, 6: 1889-1904.
-
(2007)
Eukaryot Cell
, vol.6
, pp. 1889-1904
-
-
Coste, A.1
Selmecki, A.2
Forche, A.3
-
25
-
-
33646171879
-
A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans
-
J
-
Coste A, Turner V, Ischer F, et al. A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans [J]. Genetics, 2006, 172: 2139-2156.
-
(2006)
Genetics
, vol.172
, pp. 2139-2156
-
-
Coste, A.1
Turner, V.2
Ischer, F.3
-
26
-
-
37349095258
-
The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans
-
J
-
Morschhäuser J, Barker KS, Liu TT, et al. The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans [J]. PLoS Pathog, 2007, 3: e164.
-
(2007)
PLoS Pathog
, vol.3
-
-
Morschhäuser, J.1
Barker, K.S.2
Liu, T.T.3
-
27
-
-
19344367712
-
Expression of the CDR1 efflux pump in clinical Candida albicans isolates is controlled by a negative regulatory element
-
J
-
Gaur NA, Manoharlal R, Saini P, et al. Expression of the CDR1 efflux pump in clinical Candida albicans isolates is controlled by a negative regulatory element [J]. Biochem Biophys Res Commun, 2005, 332: 206-214.
-
(2005)
Biochem Biophys Res Commun
, vol.332
, pp. 206-214
-
-
Gaur, N.A.1
Manoharlal, R.2
Saini, P.3
-
28
-
-
33746506280
-
Aneuploidy and isochromosome formation in drug-resistant Candida albicans
-
J
-
Selmecki A, Forche A, Berman J. Aneuploidy and isochromosome formation in drug-resistant Candida albicans [J]. Science, 2006, 313: 367-370.
-
(2006)
Science
, vol.313
, pp. 367-370
-
-
Selmecki, A.1
Forche, A.2
Berman, J.3
-
29
-
-
41749113291
-
An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
-
J
-
Selmecki A, Gerami-Nejad M, Paulson C, et al. An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1 [J]. Mol Microbiol, 2008, 68: 624-641.
-
(2008)
Mol Microbiol
, vol.68
, pp. 624-641
-
-
Selmecki, A.1
Gerami-Nejad, M.2
Paulson, C.3
-
30
-
-
0035992113
-
Echinocandins: A new class of antifungal
-
J
-
Denning DW. Echinocandins: a new class of antifungal [J]. J Antimicrob Chemother, 2002, 49: 889-891.
-
(2002)
J Antimicrob Chemother
, vol.49
, pp. 889-891
-
-
Denning, D.W.1
-
31
-
-
19944426581
-
Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistance
-
J
-
Monk BC, Niimi K, Lin S, et al. Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistance [J]. Antimicrob Agents Chemother, 2005, 49: 57-70.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 57-70
-
-
Monk, B.C.1
Niimi, K.2
Lin, S.3
-
32
-
-
0034021518
-
Pentamidine inhibition of group I intron splicing in Candida albicans correlates with growth inhibition
-
J
-
Miletti KE, Leibowitz MJ. Pentamidine inhibition of group I intron splicing in Candida albicans correlates with growth inhibition [J]. Antimicrob Agents Chemother, 2000, 44: 958-966.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 958-966
-
-
Miletti, K.E.1
Leibowitz, M.J.2
|