The R467K amino acid substitution in Candida albicans sterol 14α- demethylase causes drug resistance through reduced affinity

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 1, 2000, Pages 63-67

  Lamb, David C ^a   Kelly, Diane E ^a   White, Theodore C ^b   Kelly, Steven L ^a  

^a ABERYSTWYTH UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 ISOENZYME; FLUCONAZOLE; RECOMBINANT PROTEIN; STEROL 14ALPHA DEMETHYLASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CANDIDA ALBICANS; DRUG PROTEIN BINDING; DRUG RESISTANCE; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL;

EID: 0033986849     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.1.63-67.2000     Document Type: Article

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