Oxidation reactions performed by soluble methane monooxygenase hydroxylase intermediates Hperoxo and Q proceed by distinct mechanisms

Biochemistry

Volumn 49, Issue 36, 2010, Pages 7902-7912

  Tinberg, Christine E ^a   Lippard, Stephen J ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONITRILE; BOND STRENGTH (MATERIALS); CARBOXYLATION; CHEMICAL BONDS; DEUTERIUM; ENZYMES; METHANE; METHANOL; OXIDANTS; QUANTUM THEORY; RATE CONSTANTS; SUBSTRATES;

ANIONIC INTERMEDIATES; BACTERIAL ENZYMES; C-H BOND; CH-BOND ACTIVATION; DEUTERIUM KINETIC ISOTOPE EFFECT; GAIN INSIGHT; HYDROCARBON SUBSTRATES; INTERMEDIATE SPECIE; OXIDATION REACTIONS; QUANTUM-MECHANICAL TUNNELING; RATE DETERMINING STEP; SOLUBLE METHANE MONOOXYGENASE; STOPPED FLOW; TWO-ELECTRON TRANSFER;

REACTION INTERMEDIATES;

ACETONITRILE; BACTERIAL ENZYME; OXYGEN; SOLUBLE METHANE MONOOXYGENASE HYDROXYLASE; UNCLASSIFIED DRUG; DEUTERIUM; IRON; METHANE; METHANE MONOOXYGENASE; OXYGENASE;

ARTICLE; CHEMICAL BOND; ELECTRON TRANSPORT; ENZYME SUBSTRATE COMPLEX; HYDROXYLATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; QUANTUM MECHANICS; CATALYSIS; CHEMISTRY; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION;

BACTERIA (MICROORGANISMS);

CATALYSIS; DEUTERIUM; HYDROXYLATION; IRON; KINETICS; METHANE; OXIDATION-REDUCTION; OXYGENASES;

EID: 77956408219     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1009375     Document Type: Article

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