Epoxidation of olefins by cytochrome P450: Evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 7, 1998, Pages 3555-3560

  Vaz, Alfin D N ^a,b   McGinnity, Dermot F ^a,c   Coon, Minor J ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYCLOHEXENONE; ALKENE; CYTOCHROME P450; EPOXIDE; STYRENE; THREONINE;

AEROBIC METABOLISM; ARTICLE; EPOXIDATION; HYDROXYLATION; OXIDATION; PRIORITY JOURNAL; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS;

ALKENES; ANIMALS; BINDING SITES; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; MUTAGENESIS, SITE-DIRECTED; OXIDANTS; OXIDATION-REDUCTION; RATS; SUBSTRATE SPECIFICITY;

EID: 0032584090     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.7.3555     Document Type: Article

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