-
1
-
-
0027360102
-
Verbal learning and/or memory improves with glycemic control in older subjects with non-insulin-dependent diabetes mellitus
-
Gradman TJ, Laws A, Thompson LW, Reaven GM (1993) Verbal learning and/or memory improves with glycemic control in older subjects with non-insulin-dependent diabetes mellitus. J Am Geriatr Soc 41: 1305-1312.
-
(1993)
J Am Geriatr Soc
, vol.41
, pp. 1305-1312
-
-
Gradman, T.J.1
Laws, A.2
Thompson, L.W.3
Reaven, G.M.4
-
2
-
-
9644291424
-
The relationship between impaired glucose tolerance, type 2 diabetes, and cognitive function
-
Awad N, Gagnon M, Messier C (2004) The relationship between impaired glucose tolerance, type 2 diabetes, and cognitive function. J Clin Exp Neuropsychol 26: 1044-1080.
-
(2004)
J Clin Exp Neuropsychol
, vol.26
, pp. 1044-1080
-
-
Awad, N.1
Gagnon, M.2
Messier, C.3
-
3
-
-
0034707612
-
Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group
-
Gregg EW, Yaffe K, Cauley JA, Rolka DB, Blackwell TL, et al. (2000) Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Arch Intern Med 160: 174-180.
-
(2000)
Arch Intern Med
, vol.160
, pp. 174-180
-
-
Gregg, E.W.1
Yaffe, K.2
Cauley, J.A.3
Rolka, D.B.4
Blackwell, T.L.5
-
4
-
-
28444433338
-
Impact of impaired glucose tolerance and type 2 diabetes on cognitive aging
-
Messier C (2005) Impact of impaired glucose tolerance and type 2 diabetes on cognitive aging. Neurobiol Aging 26 Suppl 1: 26-30.
-
(2005)
Neurobiol Aging 26 Suppl
, vol.1
, pp. 26-30
-
-
Messier, C.1
-
5
-
-
0036362472
-
Glucose, stress, and hippocampal neuronal vulnerability
-
Reagan LP (2002) Glucose, stress, and hippocampal neuronal vulnerability. Int Rev Neurobiol 51: 289-324.
-
(2002)
Int Rev Neurobiol
, vol.51
, pp. 289-324
-
-
Reagan, L.P.1
-
6
-
-
0033759456
-
Why is learning and memory dysfunction in Type 2 diabetes limited to older adults?
-
Ryan CM, Geckle M (2000) Why is learning and memory dysfunction in Type 2 diabetes limited to older adults? Diabetes Metab Res Rev 16: 308-315.
-
(2000)
Diabetes Metab Res Rev
, vol.16
, pp. 308-315
-
-
Ryan, C.M.1
Geckle, M.2
-
7
-
-
0035947044
-
Role of insulin and insulin receptor in learning and memory
-
Zhao WQ, Alkon DL (2001) Role of insulin and insulin receptor in learning and memory. Mol Cell Endocrinol 177: 125-134.
-
(2001)
Mol Cell Endocrinol
, vol.177
, pp. 125-134
-
-
Zhao, W.Q.1
Alkon, D.L.2
-
8
-
-
56949099327
-
Time course of hippocampal IL-1 beta and memory consolidation impairments in aging rats following peripheral infection
-
Barrientos RM, Frank MG, Hein AM, Higgins EA, Watkins LR, et al. (2009) Time course of hippocampal IL-1 beta and memory consolidation impairments in aging rats following peripheral infection. Brain Behav Immun 23: 46-54.
-
(2009)
Brain Behav Immun
, vol.23
, pp. 46-54
-
-
Barrientos, R.M.1
Frank, M.G.2
Hein, A.M.3
Higgins, E.A.4
Watkins, L.R.5
-
9
-
-
26444553356
-
Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults
-
Fishel MA, Watson GS, Montine TJ, Wang Q, Green PS, et al. (2005) Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults. Arch Neurol 62: 1539-1544.
-
(2005)
Arch Neurol
, vol.62
, pp. 1539-1544
-
-
Fishel, M.A.1
Watson, G.S.2
Montine, T.J.3
Wang, Q.4
Green, P.S.5
-
10
-
-
23444443814
-
Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system
-
Godbout JP, Chen J, Abraham J, Richwine AF, Berg BM, et al. (2005) Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system. FASEB J 19: 1329-1331.
-
(2005)
FASEB J
, vol.19
, pp. 1329-1331
-
-
Godbout, J.P.1
Chen, J.2
Abraham, J.3
Richwine, A.F.4
Berg, B.M.5
-
11
-
-
0036232814
-
DNA microarray analysis of the aging brain
-
Prolla TA (2002) DNA microarray analysis of the aging brain. Chem Senses 27: 299-306.
-
(2002)
Chem Senses
, vol.27
, pp. 299-306
-
-
Prolla, T.A.1
-
12
-
-
0037936789
-
Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
-
Rosenzweig ES, Barnes CA (2003) Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog Neurobiol 69: 143-179.
-
(2003)
Prog Neurobiol
, vol.69
, pp. 143-179
-
-
Rosenzweig, E.S.1
Barnes, C.A.2
-
13
-
-
0022403407
-
An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses
-
Barnes CA, McNaughton BL (1985) An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses. Behav Neurosci 99: 1040-1048.
-
(1985)
Behav Neurosci
, vol.99
, pp. 1040-1048
-
-
Barnes, C.A.1
McNaughton, B.L.2
-
14
-
-
0036183630
-
The mechanisms of action of PPARs
-
Berger J, Moller DE (2002) The mechanisms of action of PPARs. Annu Rev Med 53: 409-435.
-
(2002)
Annu Rev Med
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
15
-
-
0036255529
-
The mode of action of thiazolidinediones
-
Hauner H (2002) The mode of action of thiazolidinediones. Diabetes Metab Res Rev 18 Suppl 2: S10-15.
-
(2002)
Diabetes Metab Res Rev
, vol.18
, Issue.SUPPL. 2
-
-
Hauner, H.1
-
16
-
-
0030658022
-
Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators
-
Martin G, Schoonjans K, Lefebvre AM, Staels B, Auwerx J (1997) Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators. J Biol Chem 272: 28210-28217.
-
(1997)
J Biol Chem
, vol.272
, pp. 28210-28217
-
-
Martin, G.1
Schoonjans, K.2
Lefebvre, A.M.3
Staels, B.4
Auwerx, J.5
-
17
-
-
0029791412
-
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans K, Peinado-Onsurbe J, Lefebvre AM, Heyman RA, Briggs M, et al. (1996) PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. Embo J 15: 5336-5348.
-
(1996)
Embo J
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.M.3
Heyman, R.A.4
Briggs, M.5
-
19
-
-
0027972524
-
Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance
-
Hofmann C, Lorenz K, Braithwaite SS, Colca JR, Palazuk BJ, et al. (1994) Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance. Endocrinology 134: 264-270.
-
(1994)
Endocrinology
, vol.134
, pp. 264-270
-
-
Hofmann, C.1
Lorenz, K.2
Braithwaite, S.S.3
Colca, J.R.4
Palazuk, B.J.5
-
20
-
-
56249140398
-
Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors
-
Hong C, Tontonoz P (2008) Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors. Curr Opin Genet Dev 18: 461-467.
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 461-467
-
-
Hong, C.1
Tontonoz, P.2
-
21
-
-
33644592598
-
Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: A preliminary study
-
Watson GS, Cholerton BA, Reger MA, Baker LD, Plymate SR, et al. (2005) Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study. Am J Geriatr Psychiatry 13: 950-958.
-
(2005)
Am J Geriatr Psychiatry
, vol.13
, pp. 950-958
-
-
Watson, G.S.1
Cholerton, B.A.2
Reger, M.A.3
Baker, L.D.4
Plymate, S.R.5
-
22
-
-
58149265311
-
Pioglitazone improved cognition in a pilot study on patients with Alzheimer's disease and mild cognitive impairment with diabetes mellitus
-
Hanyu H, Sato T, Kiuchi A, Sakurai H, Iwamoto T (2009) Pioglitazone improved cognition in a pilot study on patients with Alzheimer's disease and mild cognitive impairment with diabetes mellitus. J Am Geriatr Soc 57: 177-179.
-
(2009)
J Am Geriatr Soc
, vol.57
, pp. 177-179
-
-
Hanyu, H.1
Sato, T.2
Kiuchi, A.3
Sakurai, H.4
Iwamoto, T.5
-
23
-
-
33745266146
-
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
-
Risner ME, Saunders AM, Altman JF, Ormandy GC, Craft S, et al. (2006) Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease. Pharmacogenomics J 6: 246-254.
-
(2006)
Pharmacogenomics J
, vol.6
, pp. 246-254
-
-
Risner, M.E.1
Saunders, A.M.2
Altman, J.F.3
Ormandy, G.C.4
Craft, S.5
-
24
-
-
20444499367
-
-
Brain
-
Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, et al. (2005) Acute treatment with the PPAR{gamma} agonist pioglitazone and ibuprofen reduces glial inflammation and A{beta}1-42 levels in APPV717I transgenic mice. Brain.
-
(2005)
Acute Treatment With the PPAR{gamma} Agonist Pioglitazone and Ibuprofen Reduces Glial Inflammation and A{beta}1-42 Levels In APPV717I Transgenic Mice
-
-
Heneka, M.T.1
Sastre, M.2
Dumitrescu-Ozimek, L.3
Hanke, A.4
Dewachter, I.5
-
25
-
-
36949038203
-
The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: Therapeutic implications
-
Jiang Q, Heneka M, Landreth GE (2008) The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications. CNS Drugs 22: 1-14.
-
(2008)
CNS Drugs
, vol.22
, pp. 1-14
-
-
Jiang, Q.1
Heneka, M.2
Landreth, G.E.3
-
26
-
-
33745234766
-
Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice
-
Pedersen WA, McMillan PJ, Kulstad JJ, Leverenz JB, Craft S, et al. (2006) Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice. Exp Neurol 199: 265-273.
-
(2006)
Exp Neurol
, vol.199
, pp. 265-273
-
-
Pedersen, W.A.1
McMillan, P.J.2
Kulstad, J.J.3
Leverenz, J.B.4
Craft, S.5
-
27
-
-
4344586313
-
Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: A model revised
-
Lacombe P, Mathews PM, Schmidt SD, Breidert T, Heneka MT, et al. (2004) Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised. J Neuroinflammation 1: 11.
-
(2004)
J Neuroinflammation
, vol.1
, pp. 11
-
-
Lacombe, P.1
Mathews, P.M.2
Schmidt, S.D.3
Breidert, T.4
Heneka, M.T.5
-
28
-
-
55249125525
-
Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist
-
Nicolakakis N, Aboulkassim T, Ongali B, Lecrux C, Fernandes P, et al. (2008) Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist. J Neurosci 28: 9287-9296.
-
(2008)
J Neurosci
, vol.28
, pp. 9287-9296
-
-
Nicolakakis, N.1
Aboulkassim, T.2
Ongali, B.3
Lecrux, C.4
Fernandes, P.5
-
29
-
-
0035693506
-
Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease
-
Landreth GE, Heneka MT (2001) Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease. Neurobiol Aging 22: 937-944.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 937-944
-
-
Landreth, G.E.1
Heneka, M.T.2
-
30
-
-
0037272881
-
Therapeutic potential of peroxisome proliferator-activated receptor agonists for neurological disease
-
Feinstein DL (2003) Therapeutic potential of peroxisome proliferator-activated receptor agonists for neurological disease. Diabetes Technol Ther 5: 67-73.
-
(2003)
Diabetes Technol Ther
, vol.5
, pp. 67-73
-
-
Feinstein, D.L.1
-
31
-
-
65949114415
-
Distinct modulation of voltage-gated and ligand-gated Ca2+ currents by PPAR-gamma agonists in cultured hippocampal neurons
-
Pancani T, Phelps JT, Searcy JL, Kilgore MW, Chen KC, et al. (2009) Distinct modulation of voltage-gated and ligand-gated Ca2+ currents by PPAR-gamma agonists in cultured hippocampal neurons. J Neurochem 109: 1800-1811.
-
(2009)
J Neurochem
, vol.109
, pp. 1800-1811
-
-
Pancani, T.1
Phelps, J.T.2
Searcy, J.L.3
Kilgore, M.W.4
Chen, K.C.5
-
32
-
-
13644271368
-
Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: Role of Wnt signaling
-
Inestrosa NC, Godoy JA, Quintanilla RA, Koenig CS, Bronfman M (2005) Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling. Exp Cell Res 304: 91-104.
-
(2005)
Exp Cell Res
, vol.304
, pp. 91-104
-
-
Inestrosa, N.C.1
Godoy, J.A.2
Quintanilla, R.A.3
Koenig, C.S.4
Bronfman, M.5
-
33
-
-
0037059599
-
Troglitazone inhibits both post-glutamate neurotoxicity and low-potassium-induced apoptosis in cerebellar granule neurons
-
Uryu S, Harada J, Hisamoto M, Oda T (2002) Troglitazone inhibits both post-glutamate neurotoxicity and low-potassium-induced apoptosis in cerebellar granule neurons. Brain Res 924: 229-236.
-
(2002)
Brain Res
, vol.924
, pp. 229-236
-
-
Uryu, S.1
Harada, J.2
Hisamoto, M.3
Oda, T.4
-
34
-
-
33644934738
-
Peroxisome-proliferator-activated receptor-gamma (PPARgamma) activation protects neurons from NMDA excitotoxicity
-
Zhao X, Ou Z, Grotta JC, Waxham N, Aronowski J (2006) Peroxisome-proliferator-activated receptor-gamma (PPARgamma) activation protects neurons from NMDA excitotoxicity. Brain Res 1073-1074: 460-469.
-
(2006)
Brain Res
, vol.1073-1074
, pp. 460-469
-
-
Zhao, X.1
Ou, Z.2
Grotta, J.C.3
Waxham, N.4
Aronowski, J.5
-
35
-
-
0018777312
-
Neoplastic and nonneoplastic lesions in aging F344 rats
-
Goodman DG, Ward JM, Squire RA, Chu KC, Linhart MS (1979) Neoplastic and nonneoplastic lesions in aging F344 rats. Toxicol Appl Pharmacol 48: 237-248.
-
(1979)
Toxicol Appl Pharmacol
, vol.48
, pp. 237-248
-
-
Goodman, D.G.1
Ward, J.M.2
Squire, R.A.3
Chu, K.C.4
Linhart, M.S.5
-
38
-
-
0029822574
-
Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner
-
Moyer JR, Jr., Thompson LT, Disterhoft JF (1996) Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. J Neurosci 16: 5536-5546.
-
(1996)
J Neurosci
, vol.16
, pp. 5536-5546
-
-
Moyer Jr., J.R.1
Thompson, L.T.2
Disterhoft, J.F.3
-
39
-
-
33645450459
-
Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release
-
Gant JC, Sama MM, Landfield PW, Thibault O (2006) Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release. J Neurosci 26: 3482-3490.
-
(2006)
J Neurosci
, vol.26
, pp. 3482-3490
-
-
Gant, J.C.1
Sama, M.M.2
Landfield, P.W.3
Thibault, O.4
-
40
-
-
0022461612
-
Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation
-
Larson J, Wong D, Lynch G (1986) Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation. Brain Res 368: 347-350.
-
(1986)
Brain Res
, vol.368
, pp. 347-350
-
-
Larson, J.1
Wong, D.2
Lynch, G.3
-
41
-
-
0024162989
-
Age-dependent alterations in hippocampal synaptic plasticity: Relation to memory disorders
-
deToledo-Morrell L, Geinisman Y, Morrell F (1988) Age-dependent alterations in hippocampal synaptic plasticity: relation to memory disorders. Neurobiol Aging 9: 581-590.
-
(1988)
Neurobiol Aging
, vol.9
, pp. 581-590
-
-
Detoledo-Morrell, L.1
Geinisman, Y.2
Morrell, F.3
-
42
-
-
21344438141
-
Long-term potentiation is impaired in middle-aged rats: Regional specificity and reversal by adenosine receptor antagonists
-
Rex CS, Kramar EA, Colgin LL, Lin B, Gall CM, et al. (2005) Long-term potentiation is impaired in middle-aged rats: regional specificity and reversal by adenosine receptor antagonists. J Neurosci 25: 5956-5966.
-
(2005)
J Neurosci
, vol.25
, pp. 5956-5966
-
-
Rex, C.S.1
Kramar, E.A.2
Colgin, L.L.3
Lin, B.4
Gall, C.M.5
-
43
-
-
0037112195
-
Theta-frequency synaptic potentiation in CA1 in vitro distinguishes cognitively impaired from unimpaired aged Fischer 344 rats
-
Tombaugh GC, Rowe WB, Chow AR, Michael TH, Rose GM (2002) Theta-frequency synaptic potentiation in CA1 in vitro distinguishes cognitively impaired from unimpaired aged Fischer 344 rats. J Neurosci 22: 9932-9940.
-
(2002)
J Neurosci
, vol.22
, pp. 9932-9940
-
-
Tombaugh, G.C.1
Rowe, W.B.2
Chow, A.R.3
Michael, T.H.4
Rose, G.M.5
-
44
-
-
0031893277
-
Aging differentially alters forms of long-term potentiation in rat hippocampal area CA1
-
Shankar S, Teyler TJ, Robbins N (1998) Aging differentially alters forms of long-term potentiation in rat hippocampal area CA1. J Neurophysiol 79: 334-341.
-
(1998)
J Neurophysiol
, vol.79
, pp. 334-341
-
-
Shankar, S.1
Teyler, T.J.2
Robbins, N.3
-
45
-
-
0029976891
-
Functional integrity of NMDA-dependent LTP induction mechanisms across the lifespan of F-344 rats
-
Barnes CA, Rao G, McNaughton BL (1996) Functional integrity of NMDA-dependent LTP induction mechanisms across the lifespan of F-344 rats. Learn Mem 3: 124-137.
-
(1996)
Learn Mem
, vol.3
, pp. 124-137
-
-
Barnes, C.A.1
Rao, G.2
McNaughton, B.L.3
-
46
-
-
0027193830
-
Age-related alterations in potentiation in the CA1 region in F344 rats
-
Deupree DL, Bradley J, Turner DA (1993) Age-related alterations in potentiation in the CA1 region in F344 rats. Neurobiol Aging 14: 249-258.
-
(1993)
Neurobiol Aging
, vol.14
, pp. 249-258
-
-
Deupree, D.L.1
Bradley, J.2
Turner, D.A.3
-
47
-
-
33947534891
-
Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats
-
Rowe WB, Blalock EM, Chen KC, Kadish I, Wang D, et al. (2007) Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J Neurosci 27: 3098-3110.
-
(2007)
J Neurosci
, vol.27
, pp. 3098-3110
-
-
Rowe, W.B.1
Blalock, E.M.2
Chen, K.C.3
Kadish, I.4
Wang, D.5
-
48
-
-
60849111389
-
Hippocampal and cognitive aging across the lifespan: A bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment
-
Kadish I, Thibault O, Blalock EM, Chen KC, Gant JC, et al. (2009) Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. J Neurosci 29: 1805-1816.
-
(2009)
J Neurosci
, vol.29
, pp. 1805-1816
-
-
Kadish, I.1
Thibault, O.2
Blalock, E.M.3
Chen, K.C.4
Gant, J.C.5
-
49
-
-
1242341923
-
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
-
Blalock EM, Geddes JW, Chen KC, Porter NM, Markesbery WR, et al. (2004) Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc Natl Acad Sci U S A 101: 2173-2178.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2173-2178
-
-
Blalock, E.M.1
Geddes, J.W.2
Chen, K.C.3
Porter, N.M.4
Markesbery, W.R.5
-
50
-
-
0038206578
-
Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment
-
Blalock EM, Chen KC, Sharrow K, Herman JP, Porter NM, et al. (2003) Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci 23: 3807-3819.
-
(2003)
J Neurosci
, vol.23
, pp. 3807-3819
-
-
Blalock, E.M.1
Chen, K.C.2
Sharrow, K.3
Herman, J.P.4
Porter, N.M.5
-
51
-
-
33645274977
-
Quality Assessment of Affymetrix GeneChip Data
-
Gentleman R, Carey V, Huber W, Irizarry R, Dudoit S, eds, Springer
-
Bolstad BM, Collin F, Brettschneider J, Simpson K, Cope L, et al. (2005) Quality Assessment of Affymetrix GeneChip Data. In: Gentleman R, Carey V, Huber W, Irizarry R, Dudoit S, eds. Bioinformatics and Computational Biology Solutions Using R and Bioconductor Springer.
-
(2005)
Bioinformatics and Computational Biology Solutions Using R and Bioconductor
-
-
Bolstad, B.M.1
Collin, F.2
Brettschneider, J.3
Simpson, K.4
Cope, L.5
-
52
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80.
-
(2004)
Genome Biol
, vol.5
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
Bolstad, B.4
Dettling, M.5
-
53
-
-
0037311919
-
TM4: A free, open-source system for microarray data management and analysis
-
Saeed AI, Sharov V, White J, Li J, Liang W, et al. (2003) TM4: a free, open-source system for microarray data management and analysis. Biotechniques 34: 374-378.
-
(2003)
Biotechniques
, vol.34
, pp. 374-378
-
-
Saeed, A.I.1
Sharov, V.2
White, J.3
Li, J.4
Liang, W.5
-
54
-
-
41349115432
-
The DAVID Gene Functional Classification Tool: A novel biological module-centric algorithm to functionally analyze large gene lists
-
Huang da W, Sherman BT, Tan Q, Collins JR, Alvord WG, et al. (2007) The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biol 8: R183.
-
(2007)
Genome Biol
, vol.8
-
-
Huang, W.D.1
Sherman, B.T.2
Tan, Q.3
Collins, J.R.4
Alvord, W.G.5
-
55
-
-
0035829361
-
Controlling the false discovery rate in behavior genetics research
-
Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I (2001) Controlling the false discovery rate in behavior genetics research. Behav Brain Res 125: 279-284.
-
(2001)
Behav Brain Res
, vol.125
, pp. 279-284
-
-
Benjamini, Y.1
Drai, D.2
Elmer, G.3
Kafkafi, N.4
Golani, I.5
-
56
-
-
0036203666
-
Effects of pioglitazone and rosiglitazone on blood lipid levels and glycemic control in patients with type 2 diabetes mellitus: A retrospective review of randomly selected medical records
-
Boyle PJ, King AB, Olansky L, Marchetti A, Lau H, et al. (2002) Effects of pioglitazone and rosiglitazone on blood lipid levels and glycemic control in patients with type 2 diabetes mellitus: a retrospective review of randomly selected medical records. Clin Ther 24: 378-396.
-
(2002)
Clin Ther
, vol.24
, pp. 378-396
-
-
Boyle, P.J.1
King, A.B.2
Olansky, L.3
Marchetti, A.4
Lau, H.5
-
57
-
-
35148837113
-
Pioglitazone and rosiglitazone have different effects on serum lipoprotein particle concentrations and sizes in patients with type 2 diabetes and dyslipidemia
-
Deeg MA, Buse JB, Goldberg RB, Kendall DM, Zagar AJ, et al. (2007) Pioglitazone and rosiglitazone have different effects on serum lipoprotein particle concentrations and sizes in patients with type 2 diabetes and dyslipidemia. Diabetes Care 30: 2458-2464.
-
(2007)
Diabetes Care
, vol.30
, pp. 2458-2464
-
-
Deeg, M.A.1
Buse, J.B.2
Goldberg, R.B.3
Kendall, D.M.4
Zagar, A.J.5
-
58
-
-
21544466158
-
A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia
-
Goldberg RB, Kendall DM, Deeg MA, Buse JB, Zagar AJ, et al. (2005) A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia. Diabetes Care 28: 1547-1554.
-
(2005)
Diabetes Care
, vol.28
, pp. 1547-1554
-
-
Goldberg, R.B.1
Kendall, D.M.2
Deeg, M.A.3
Buse, J.B.4
Zagar, A.J.5
-
59
-
-
33644826717
-
Effects of pioglitazone on lipoproteins, inflammatory markers, and adipokines in nondiabetic patients with metabolic syndrome
-
Szapary PO, Bloedon LT, Samaha FF, Duffy D, Wolfe ML, et al. (2006) Effects of pioglitazone on lipoproteins, inflammatory markers, and adipokines in nondiabetic patients with metabolic syndrome. Arterioscler Thromb Vasc Biol 26: 182-188.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 182-188
-
-
Szapary, P.O.1
Bloedon, L.T.2
Samaha, F.F.3
Duffy, D.4
Wolfe, M.L.5
-
60
-
-
67649354213
-
Long-term lipid effects of pioglitazone by baseline anti-hyperglycemia medication therapy and statin use from the PROactive experience (PROactive 14)
-
Spanheimer R, Betteridge DJ, Tan MH, Ferrannini E, Charbonnel B (2009) Long-term lipid effects of pioglitazone by baseline anti-hyperglycemia medication therapy and statin use from the PROactive experience (PROactive 14). Am J Cardiol 104: 234-239.
-
(2009)
Am J Cardiol
, vol.104
, pp. 234-239
-
-
Spanheimer, R.1
Betteridge, D.J.2
Tan, M.H.3
Ferrannini, E.4
Charbonnel, B.5
-
61
-
-
37149034178
-
Thiazolidinediones and cardiovascular outcomes in older patients with diabetes
-
Lipscombe LL, Gomes T, Levesque LE, Hux JE, Juurlink DN, et al. (2007) Thiazolidinediones and cardiovascular outcomes in older patients with diabetes. Jama 298: 2634-2643.
-
(2007)
Jama
, vol.298
, pp. 2634-2643
-
-
Lipscombe, L.L.1
Gomes, T.2
Levesque, L.E.3
Hux, J.E.4
Juurlink, D.N.5
-
62
-
-
0027214025
-
Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze
-
Gallagher M, Burwell R, Burchinal M (1993) Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze. Behav Neurosci 107: 618-626.
-
(1993)
Behav Neurosci
, vol.107
, pp. 618-626
-
-
Gallagher, M.1
Burwell, R.2
Burchinal, M.3
-
63
-
-
0027070788
-
Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age-and concentration-dependent manner
-
Moyer JR, Jr., Thompson LT, Black JP, Disterhoft JF (1992) Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age-and concentration-dependent manner. J Neurophysiol 68: 2100-2109.
-
(1992)
J Neurophysiol
, vol.68
, pp. 2100-2109
-
-
Moyer Jr., J.R.1
Thompson, L.T.2
Black, J.P.3
Disterhoft, J.F.4
-
64
-
-
0021645626
-
Prolonged Ca2+-dependent afterhyperpolar-izations in hippocampal neurons of aged rats
-
Landfield PW, Pitler TA (1984) Prolonged Ca2+-dependent afterhyperpolar-izations in hippocampal neurons of aged rats. Science 226: 1089-1092.
-
(1984)
Science
, vol.226
, pp. 1089-1092
-
-
Landfield, P.W.1
Pitler, T.A.2
-
65
-
-
0030567767
-
Calcium-dependent afterhyperpolarization and learning in young and aging hippocam-pus
-
Disterhoft JF, Thompson LT, Moyer JR, Jr., Mogul DJ (1996) Calcium-dependent afterhyperpolarization and learning in young and aging hippocam-pus. Life Sci 59: 413-420.
-
(1996)
Life Sci
, vol.59
, pp. 413-420
-
-
Disterhoft, J.F.1
Thompson, L.T.2
Moyer Jr., J.R.3
Mogul, D.J.4
-
67
-
-
34249051111
-
Calcium homeostasis and modulation of synaptic plasticity in the aged brain
-
Foster TC (2007) Calcium homeostasis and modulation of synaptic plasticity in the aged brain. Aging Cell 6: 319-325.
-
(2007)
Aging Cell
, vol.6
, pp. 319-325
-
-
Foster, T.C.1
-
68
-
-
36348947406
-
Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons
-
Storozhevykh TP, Senilova YE, Persiyantseva NA, Pinelis VG, Pomytkin IA (2007) Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons. BMC Neurosci 8: 84.
-
(2007)
BMC Neurosci
, vol.8
, pp. 84
-
-
Storozhevykh, T.P.1
Senilova, Y.E.2
Persiyantseva, N.A.3
Pinelis, V.G.4
Pomytkin, I.A.5
-
69
-
-
0000847978
-
Gene-expression profile of the ageing brain in mice
-
Lee CK, Weindruch R, Prolla TA (2000) Gene-expression profile of the ageing brain in mice. Nat Genet 25: 294-297.
-
(2000)
Nat Genet
, vol.25
, pp. 294-297
-
-
Lee, C.K.1
Weindruch, R.2
Prolla, T.A.3
-
70
-
-
33750522659
-
Changes in transcription within the CA1 field of the hippocampus are associated with age-related spatial learning impairments
-
Burger C, Lopez MC, Feller JA, Baker HV, Muzyczka N, et al. (2007) Changes in transcription within the CA1 field of the hippocampus are associated with age-related spatial learning impairments. Neurobiol Learn Mem 87: 21-41.
-
(2007)
Neurobiol Learn Mem
, vol.87
, pp. 21-41
-
-
Burger, C.1
Lopez, M.C.2
Feller, J.A.3
Baker, H.V.4
Muzyczka, N.5
-
71
-
-
0031057599
-
Disposition of the new antidiabetic agent pioglitazone in rats, dogs, and monkeys
-
Maeshiba Y, Kiyota Y, Yamashita K, Yoshimura Y, Motohashi M, et al. (1997) Disposition of the new antidiabetic agent pioglitazone in rats, dogs, and monkeys. Arzneimittelforschung 47: 29-35.
-
(1997)
Arzneimittelforschung
, vol.47
, pp. 29-35
-
-
Maeshiba, Y.1
Kiyota, Y.2
Yamashita, K.3
Yoshimura, Y.4
Motohashi, M.5
-
72
-
-
3042699619
-
Attenuated inhibition of L-type calcium currents by troglitazone in fructose-fed rat cardiac ventricular myocytes
-
Arikawa M, Takahashi N, Kira T, Hara M, Yoshimatsu H, et al. (2004) Attenuated inhibition of L-type calcium currents by troglitazone in fructose-fed rat cardiac ventricular myocytes. J Cardiovasc Pharmacol 44: 109-116.
-
(2004)
J Cardiovasc Pharmacol
, vol.44
, pp. 109-116
-
-
Arikawa, M.1
Takahashi, N.2
Kira, T.3
Hara, M.4
Yoshimatsu, H.5
-
73
-
-
0032727040
-
Troglitazone and pioglitazone attenuate agonist-dependent Ca2+ mobilization and cell proliferation in vascular smooth muscle cells
-
Asano M, Nakajima T, Iwasawa K, Morita T, Nakamura F, et al. (1999) Troglitazone and pioglitazone attenuate agonist-dependent Ca2+ mobilization and cell proliferation in vascular smooth muscle cells. Br J Pharmacol 128: 673-683.
-
(1999)
Br J Pharmacol
, vol.128
, pp. 673-683
-
-
Asano, M.1
Nakajima, T.2
Iwasawa, K.3
Morita, T.4
Nakamura, F.5
-
74
-
-
10844281766
-
Novel PPARgamma agonists GI 262570, GW 7845, GW 1929, and pioglitazone decrease calcium channel function and myogenic tone in rat mesenteric arteries
-
Heppner TJ, Bonev AD, Eckman DM, Gomez MF, Petkov GV, et al. (2005) Novel PPARgamma agonists GI 262570, GW 7845, GW 1929, and pioglitazone decrease calcium channel function and myogenic tone in rat mesenteric arteries. Pharmacology 73: 15-22.
-
(2005)
Pharmacology
, vol.73
, pp. 15-22
-
-
Heppner, T.J.1
Bonev, A.D.2
Eckman, D.M.3
Gomez, M.F.4
Petkov, G.V.5
-
75
-
-
0032544632
-
Effects of troglitazone and pioglitazone on the action potentials and membrane currents of rabbit ventricular myocytes
-
Ikeda S, Watanabe T (1998) Effects of troglitazone and pioglitazone on the action potentials and membrane currents of rabbit ventricular myocytes. Eur J Pharmacol 357: 243-250.
-
(1998)
Eur J Pharmacol
, vol.357
, pp. 243-250
-
-
Ikeda, S.1
Watanabe, T.2
-
76
-
-
0033536075
-
Troglitazone inhibits voltage-dependent calcium currents in guinea pig cardiac myocytes
-
Nakajima T, Iwasawa K, Oonuma H, Imuta H, Hazama H, et al. (1999) Troglitazone inhibits voltage-dependent calcium currents in guinea pig cardiac myocytes. Circulation 99: 2942-2950.
-
(1999)
Circulation
, vol.99
, pp. 2942-2950
-
-
Nakajima, T.1
Iwasawa, K.2
Oonuma, H.3
Imuta, H.4
Hazama, H.5
-
77
-
-
0030989050
-
Troglitazone reduces contraction by inhibition of vascular smooth muscle cell Ca2+ currents and not endothelial nitric oxide production
-
Song J, Walsh MF, Igwe R, Ram JL, Barazi M, et al. (1997) Troglitazone reduces contraction by inhibition of vascular smooth muscle cell Ca2+ currents and not endothelial nitric oxide production. Diabetes 46: 659-664.
-
(1997)
Diabetes
, vol.46
, pp. 659-664
-
-
Song, J.1
Walsh, M.F.2
Igwe, R.3
Ram, J.L.4
Barazi, M.5
-
78
-
-
34249075140
-
Alterations in intrinsic neuronal excitability during normal aging
-
Disterhoft JF, Oh MM (2007) Alterations in intrinsic neuronal excitability during normal aging. Aging Cell 6: 327-336.
-
(2007)
Aging Cell
, vol.6
, pp. 327-336
-
-
Disterhoft, J.F.1
Oh, M.M.2
-
79
-
-
33947493213
-
Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: Minding the store
-
Thibault O, Gant JC, Landfield PW (2007) Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell 6: 307-317.
-
(2007)
Aging Cell
, vol.6
, pp. 307-317
-
-
Thibault, O.1
Gant, J.C.2
Landfield, P.W.3
-
80
-
-
0029782113
-
Increase in single L-type calcium channels in hippocampal neurons during aging
-
Thibault O, Landfield PW (1996) Increase in single L-type calcium channels in hippocampal neurons during aging. Science 272: 1017-1020.
-
(1996)
Science
, vol.272
, pp. 1017-1020
-
-
Thibault, O.1
Landfield, P.W.2
-
81
-
-
0035988192
-
Diabetes-induced alterations in calcium homeostasis in sensory neurones of streptozotocin-diabetic rats are restricted to lumbar ganglia and are prevented by neurotrophin-3
-
Huang TJ, Sayers NM, Fernyhough P, Verkhratsky A (2002) Diabetes-induced alterations in calcium homeostasis in sensory neurones of streptozotocin-diabetic rats are restricted to lumbar ganglia and are prevented by neurotrophin-3. Diabetologia 45: 560-570.
-
(2002)
Diabetologia
, vol.45
, pp. 560-570
-
-
Huang, T.J.1
Sayers, N.M.2
Fernyhough, P.3
Verkhratsky, A.4
-
82
-
-
10644221251
-
Insulin enhances mitochon-drial inner membrane potential and increases ATP levels through phospho-inositide 3-kinase in adult sensory neurons
-
Huang TJ, Verkhratsky A, Fernyhough P (2005) Insulin enhances mitochon-drial inner membrane potential and increases ATP levels through phospho-inositide 3-kinase in adult sensory neurons. Mol Cell Neurosci 28: 42-54.
-
(2005)
Mol Cell Neurosci
, vol.28
, pp. 42-54
-
-
Huang, T.J.1
Verkhratsky, A.2
Fernyhough, P.3
-
83
-
-
0037426572
-
Increased spike broadening and slow afterhyperpolarization in CA1 pyramidal cells of streptozotocin-induced diabetic rats
-
Kamal A, Artola A, Biessels GJ, Gispen WH, Ramakers GM (2003) Increased spike broadening and slow afterhyperpolarization in CA1 pyramidal cells of streptozotocin-induced diabetic rats. Neuroscience 118: 577-583.
-
(2003)
Neuroscience
, vol.118
, pp. 577-583
-
-
Kamal, A.1
Artola, A.2
Biessels, G.J.3
Gispen, W.H.4
Ramakers, G.M.5
-
84
-
-
3442902549
-
Diabetes-induced abnormalities in ER calcium mobilization in primary and secondary nociceptive neurons
-
Kruglikov I, Gryshchenko O, Shutov L, Kostyuk E, Kostyuk P, et al. (2004) Diabetes-induced abnormalities in ER calcium mobilization in primary and secondary nociceptive neurons. Pflugers Arch 448: 395-401.
-
(2004)
Pflugers Arch
, vol.448
, pp. 395-401
-
-
Kruglikov, I.1
Gryshchenko, O.2
Shutov, L.3
Kostyuk, E.4
Kostyuk, P.5
-
85
-
-
0024428429
-
Mechanism of insulin resistance induced by sustained levels of cytosolic free calcium in rat adipocytes
-
Draznin B, Lewis D, Houlder N, Sherman N, Adamo M, et al. (1989) Mechanism of insulin resistance induced by sustained levels of cytosolic free calcium in rat adipocytes. Endocrinology 125: 2341-2349.
-
(1989)
Endocrinology
, vol.125
, pp. 2341-2349
-
-
Draznin, B.1
Lewis, D.2
Houlder, N.3
Sherman, N.4
Adamo, M.5
-
86
-
-
58149485983
-
Rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an Alzheimer's disease mouse model
-
Escribano L, Simon AM, Perez-Mediavilla A, Salazar-Colocho P, Del Rio J, et al. (2009) Rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an Alzheimer's disease mouse model. Biochem Biophys Res Commun 379: 406-410.
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 406-410
-
-
Escribano, L.1
Simon, A.M.2
Perez-Mediavilla, A.3
Salazar-Colocho, P.4
Rio, J.D.5
-
87
-
-
0024433594
-
Corticosteroid modulation of hippocampal potentials: Increased effect with aging
-
Kerr DS, Campbell LW, Hao SY, Landfield PW (1989) Corticosteroid modulation of hippocampal potentials: increased effect with aging. Science 245: 1505-1509.
-
(1989)
Science
, vol.245
, pp. 1505-1509
-
-
Kerr, D.S.1
Campbell, L.W.2
Hao, S.Y.3
Landfield, P.W.4
-
88
-
-
0028825920
-
Compensatory alterations for insulin signal transduction and glucose transport in insulin-resistant diabetes
-
Bonini JA, Colca JR, Dailey C, White M, Hofmann C (1995) Compensatory alterations for insulin signal transduction and glucose transport in insulin-resistant diabetes. Am J Physiol 269: E759-765.
-
(1995)
Am J Physiol
, vol.269
-
-
Bonini, J.A.1
Colca, J.R.2
Dailey, C.3
White, M.4
Hofmann, C.5
-
89
-
-
33748755428
-
Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease
-
de la Monte SM, Tong M, Lester-Coll N, Plater M, Jr., Wands JR (2006) Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease. J Alzheimers Dis 10: 89-109.
-
(2006)
J Alzheimers Dis
, vol.10
, pp. 89-109
-
-
Monte, S.M.D.L.1
Tong, M.2
Lester-Coll, N.3
Plater Jr., M.4
Wands, J.R.5
-
90
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?
-
Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, et al. (2005) Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimers Dis 7: 63-80.
-
(2005)
J Alzheimers Dis
, vol.7
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
Cannon, J.L.4
Neely, T.R.5
-
91
-
-
0037221379
-
The role of insulin resistance in the pathogenesis of Alzheimer's disease: Implications for treatment
-
Watson GS, Craft S (2003) The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment. CNS Drugs 17: 27-45.
-
(2003)
CNS Drugs
, vol.17
, pp. 27-45
-
-
Watson, G.S.1
Craft, S.2
-
92
-
-
0028887744
-
Relationship between changes in body composition and insulin responsiveness in models of the aging rat
-
Barzilai N, Rossetti L (1995) Relationship between changes in body composition and insulin responsiveness in models of the aging rat. Am J Physiol 269: E591-597.
-
(1995)
Am J Physiol
, vol.269
-
-
Barzilai, N.1
Rossetti, L.2
-
93
-
-
0020826161
-
Relationship between sympathetic activity and diet-induced obesity in two rat strains
-
Levin BE, Triscari J, Sullivan AC (1983) Relationship between sympathetic activity and diet-induced obesity in two rat strains. Am J Physiol 245: R364-371.
-
(1983)
Am J Physiol
, vol.245
-
-
Levin, B.E.1
Triscari, J.2
Sullivan, A.C.3
-
94
-
-
0033551134
-
Cyclopentenone prostaglandins suppress activation of microglia: Down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2
-
Petrova TV, Akama KT, Van Eldik LJ (1999) Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2. Proc Natl Acad Sci U S A 96: 4668-4673.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 4668-4673
-
-
Petrova, T.V.1
Akama, K.T.2
van Eldik, L.J.3
-
95
-
-
0034651101
-
Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists
-
Combs CK, Johnson DE, Karlo JC, Cannady SB, Landreth GE (2000) Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. J Neurosci 20: 558-567.
-
(2000)
J Neurosci
, vol.20
, pp. 558-567
-
-
Combs, C.K.1
Johnson, D.E.2
Karlo, J.C.3
Cannady, S.B.4
Landreth, G.E.5
-
96
-
-
0033378706
-
Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase
-
Heneka MT, Feinstein DL, Galea E, Gleichmann M, Wullner U, et al. (1999) Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase. J Neuroimmunol 100: 156-168.
-
(1999)
J Neuroimmunol
, vol.100
, pp. 156-168
-
-
Heneka, M.T.1
Feinstein, D.L.2
Galea, E.3
Gleichmann, M.4
Wullner, U.5
-
97
-
-
0031888958
-
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
-
Jiang C, Ting AT, Seed B (1998) PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391: 82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
98
-
-
0034121698
-
Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene
-
Li M, Pascual G, Glass CK (2000) Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene. Mol Cell Biol 20: 4699-4707.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4699-4707
-
-
Li, M.1
Pascual, G.2
Glass, C.K.3
-
99
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK (1998) The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391: 79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
100
-
-
33947204503
-
Peroxisome proliferator-activated receptor-gamma agonists induce neuropro-tection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents
-
Tureyen K, Kapadia R, Bowen KK, Satriotomo I, Liang J, et al. (2007) Peroxisome proliferator-activated receptor-gamma agonists induce neuropro-tection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. J Neurochem 101: 41-56.
-
(2007)
J Neurochem
, vol.101
, pp. 41-56
-
-
Tureyen, K.1
Kapadia, R.2
Bowen, K.K.3
Satriotomo, I.4
Liang, J.5
-
101
-
-
77956403679
-
Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema
-
Morgenweck J, Abdel-Aleem OS, McNamara KC, Donahue RR, Badr MZ, et al. (2009) Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema. Neuropharmacology.
-
(2009)
Neuropharmacology
-
-
Morgenweck, J.1
Abdel-Aleem, O.S.2
McNamara, K.C.3
Donahue, R.R.4
Badr, M.Z.5
-
102
-
-
45549087654
-
Intrathecal rosiglitazone acts at peroxisome proliferator-activated receptor-gamma to rapidly inhibit neuropathic pain in rats
-
Churi SB, Abdel-Aleem OS, Tumber KK, Scuderi-Porter H, Taylor BK (2008) Intrathecal rosiglitazone acts at peroxisome proliferator-activated receptor-gamma to rapidly inhibit neuropathic pain in rats. J Pain 9: 639-649.
-
(2008)
J Pain
, vol.9
, pp. 639-649
-
-
Churi, S.B.1
Abdel-Aleem, O.S.2
Tumber, K.K.3
Scuderi-Porter, H.4
Taylor, B.K.5
-
103
-
-
0038153961
-
Neuroprotective effects of PPARgamma agonists against oxidative insults in HT-22 cells
-
Aoun P, Watson DG, Simpkins JW (2003) Neuroprotective effects of PPARgamma agonists against oxidative insults in HT-22 cells. Eur J Pharmacol 472: 65-71.
-
(2003)
Eur J Pharmacol
, vol.472
, pp. 65-71
-
-
Aoun, P.1
Watson, D.G.2
Simpkins, J.W.3
-
104
-
-
16844374020
-
Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats
-
Garcia-Bueno B, Madrigal JL, Lizasoain I, Moro MA, Lorenzo P, et al. (2005) Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats. Biol Psychiatry 57: 885-894.
-
(2005)
Biol Psychiatry
, vol.57
, pp. 885-894
-
-
Garcia-Bueno, B.1
Madrigal, J.L.2
Lizasoain, I.3
Moro, M.A.4
Lorenzo, P.5
-
105
-
-
0034666289
-
Peroxisome proliferatoractivated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo
-
Heneka MT, Klockgether T, Feinstein DL (2000) Peroxisome proliferatoractivated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. J Neurosci 20: 6862-6867.
-
(2000)
J Neurosci
, vol.20
, pp. 6862-6867
-
-
Heneka, M.T.1
Klockgether, T.2
Feinstein, D.L.3
-
106
-
-
39149116014
-
Protective properties afforded by pioglitazone against intrastriatal LPS in Sprague-Dawley rats
-
Hunter RL, Choi DY, Ross SA, Bing G (2008) Protective properties afforded by pioglitazone against intrastriatal LPS in Sprague-Dawley rats. Neurosci Lett 432: 198-201.
-
(2008)
Neurosci Lett
, vol.432
, pp. 198-201
-
-
Hunter, R.L.1
Choi, D.Y.2
Ross, S.A.3
Bing, G.4
-
107
-
-
34250741677
-
Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection
-
Romera C, Hurtado O, Mallolas J, Pereira MP, Morales JR, et al. (2007) Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection. J Cereb Blood Flow Metab 27: 1327-1338.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1327-1338
-
-
Romera, C.1
Hurtado, O.2
Mallolas, J.3
Pereira, M.P.4
Morales, J.R.5
-
108
-
-
0036326074
-
Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease
-
Breidert T, Callebert J, Heneka MT, Landreth G, Launay JM, et al. (2002) Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. J Neurochem 82: 615-624.
-
(2002)
J Neurochem
, vol.82
, pp. 615-624
-
-
Breidert, T.1
Callebert, J.2
Heneka, M.T.3
Landreth, G.4
Launay, J.M.5
-
109
-
-
33748909537
-
Altered PPARgamma expression and activation after transient focal ischemia in rats
-
Victor NA, Wanderi EW, Gamboa J, Zhao X, Aronowski J, et al. (2006) Altered PPARgamma expression and activation after transient focal ischemia in rats. Eur J Neurosci 24: 1653-1663.
-
(2006)
Eur J Neurosci
, vol.24
, pp. 1653-1663
-
-
Victor, N.A.1
Wanderi, E.W.2
Gamboa, J.3
Zhao, X.4
Aronowski, J.5
-
110
-
-
0347087323
-
Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation
-
Dehmer T, Heneka MT, Sastre M, Dichgans J, Schulz JB (2004) Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. J Neurochem 88: 494-501.
-
(2004)
J Neurochem
, vol.88
, pp. 494-501
-
-
Dehmer, T.1
Heneka, M.T.2
Sastre, M.3
Dichgans, J.4
Schulz, J.B.5
-
111
-
-
38449085356
-
Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists
-
Kapadia R, Yi JH, Vemuganti R (2008) Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists. Front Biosci 13: 1813-1826.
-
(2008)
Front Biosci
, vol.13
, pp. 1813-1826
-
-
Kapadia, R.1
Yi, J.H.2
Vemuganti, R.3
-
112
-
-
10044289268
-
Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia
-
Sundararajan S, Gamboa JL, Victor NA, Wanderi EW, Lust WD, et al. (2005) Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia. Neuroscience 130: 685-696.
-
(2005)
Neuroscience
, vol.130
, pp. 685-696
-
-
Sundararajan, S.1
Gamboa, J.L.2
Victor, N.A.3
Wanderi, E.W.4
Lust, W.D.5
-
113
-
-
9644268167
-
Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease
-
Pedersen WA, Flynn ER (2004) Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease. Neurobiol Dis 17: 500-506.
-
(2004)
Neurobiol Dis
, vol.17
, pp. 500-506
-
-
Pedersen, W.A.1
Flynn, E.R.2
-
114
-
-
0041921071
-
Antiinflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease
-
Yan Q, Zhang J, Liu H, Babu-Khan S, Vassar R, et al. (2003) Antiinflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease. J Neurosci 23: 7504-7509.
-
(2003)
J Neurosci
, vol.23
, pp. 7504-7509
-
-
Yan, Q.1
Zhang, J.2
Liu, H.3
Babu-Khan, S.4
Vassar, R.5
-
115
-
-
6344273111
-
Rosiglitazone improves contextual fear conditioning in aged rats
-
Gemma C, Stellwagen H, Fister M, Coultrap SJ, Mesches MH, et al. (2004) Rosiglitazone improves contextual fear conditioning in aged rats. Neuroreport 15: 2255-2259.
-
(2004)
Neuroreport
, vol.15
, pp. 2255-2259
-
-
Gemma, C.1
Stellwagen, H.2
Fister, M.3
Coultrap, S.J.4
Mesches, M.H.5
-
116
-
-
65249171482
-
Estrogen effects on cognition and hippocampal transcription in middle-aged mice
-
Aenlle KK, Kumar A, Cui L, Jackson TC, Foster TC (2009) Estrogen effects on cognition and hippocampal transcription in middle-aged mice. Neurobiol Aging 30: 932-945.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 932-945
-
-
Aenlle, K.K.1
Kumar, A.2
Cui, L.3
Jackson, T.C.4
Foster, T.C.5
-
117
-
-
41649089292
-
Genomewide analysis of aging and learning-related genes in the hippocampal dentate gyrus
-
Burger C, Lopez MC, Baker HV, Mandel RJ, Muzyczka N (2008) Genomewide analysis of aging and learning-related genes in the hippocampal dentate gyrus. Neurobiol Learn Mem 89: 379-396.
-
(2008)
Neurobiol Learn Mem
, vol.89
, pp. 379-396
-
-
Burger, C.1
Lopez, M.C.2
Baker, H.V.3
Mandel, R.J.4
Muzyczka, N.5
-
118
-
-
35148863154
-
Inflammatory changes parallel the early stages of Alzheimer disease
-
Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, et al. (2007) Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiol Aging 28: 1821-1833.
-
(2007)
Neurobiol Aging
, vol.28
, pp. 1821-1833
-
-
Parachikova, A.1
Agadjanyan, M.G.2
Cribbs, D.H.3
Blurton-Jones, M.4
Perreau, V.5
-
119
-
-
72449196408
-
Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice
-
Stranahan AM, Lee K, Becker KG, Zhang Y, Maudsley S, et al. (2008) Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice. Neurobiol Aging.
-
(2008)
Neurobiol Aging
-
-
Stranahan, A.M.1
Lee, K.2
Becker, K.G.3
Zhang, Y.4
Maudsley, S.5
-
120
-
-
64549158079
-
Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress
-
Wang X, Zaidi A, Pal R, Garrett AS, Braceras R, et al. (2009) Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress. BMC Neurosci 10: 12.
-
(2009)
BMC Neurosci
, vol.10
, pp. 12
-
-
Wang, X.1
Zaidi, A.2
Pal, R.3
Garrett, A.S.4
Braceras, R.5
-
121
-
-
67651166868
-
Pioglitazone inhibits Toll-like receptor expression and activity in human monocytes and db/db mice
-
Dasu MR, Park S, Devaraj S, Jialal I (2009) Pioglitazone inhibits Toll-like receptor expression and activity in human monocytes and db/db mice. Endocrinology 150: 3457-3464.
-
(2009)
Endocrinology
, vol.150
, pp. 3457-3464
-
-
Dasu, M.R.1
Park, S.2
Devaraj, S.3
Jialal, I.4
|