메뉴 건너뛰기




Volumn 379, Issue 2, 2009, Pages 406-410

Rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an Alzheimer's disease mouse model

Author keywords

Alzheimer's disease; Glucocorticoids; Hippocampus; Memory; Peroxisome proliferator activated receptor

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE;

EID: 58149485983     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.12.071     Document Type: Article
Times cited : (124)

References (30)
  • 1
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297 (2002) 353-356
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 2
    • 5344277556 scopus 로고    scopus 로고
    • Deciphering the molecular basis of memory failure in Alzheimer's disease
    • Walsh D.M., and Selkoe D.J. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 44 (2004) 181-193
    • (2004) Neuron , vol.44 , pp. 181-193
    • Walsh, D.M.1    Selkoe, D.J.2
  • 3
    • 27844472159 scopus 로고    scopus 로고
    • Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology?
    • Biessels G.J., and Kappelle L.J. Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology?. Biochem. Soc. Trans. 33 (2005) 1041-1044
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 1041-1044
    • Biessels, G.J.1    Kappelle, L.J.2
  • 4
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann J.M., Moore L.B., Smith-Oliver T.A., Wilkison W.O., Willson T.M., and Kliewer S.A. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J. Biol. Chem. 270 (1995) 12953-12956
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 8
    • 55249125525 scopus 로고    scopus 로고
    • Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist
    • Nicolakakis N., Aboulkassim T., Ongali B., Lecrux C., Fernandes P., Rosa-Neto P., Tong X.K., and Hamel E. Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist. J. Neurosci. 28 (2008) 9287-9296
    • (2008) J. Neurosci. , vol.28 , pp. 9287-9296
    • Nicolakakis, N.1    Aboulkassim, T.2    Ongali, B.3    Lecrux, C.4    Fernandes, P.5    Rosa-Neto, P.6    Tong, X.K.7    Hamel, E.8
  • 11
    • 0242609178 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase
    • Sastre M., Dewachter I., Landreth G.E., Willson T.M., Klockgether T., van Leuven F., and Heneka M.T. Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. J. Neurosci. 23 (2003) 9796-9804
    • (2003) J. Neurosci. , vol.23 , pp. 9796-9804
    • Sastre, M.1    Dewachter, I.2    Landreth, G.E.3    Willson, T.M.4    Klockgether, T.5    van Leuven, F.6    Heneka, M.T.7
  • 12
    • 10044225937 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide
    • Camacho I.E., Serneels L., Spittaels K., Merchiers P., Dominguez D., and De Strooper B. Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide. J. Neurosci. 24 (2004) 10908-10917
    • (2004) J. Neurosci. , vol.24 , pp. 10908-10917
    • Camacho, I.E.1    Serneels, L.2    Spittaels, K.3    Merchiers, P.4    Dominguez, D.5    De Strooper, B.6
  • 15
    • 30944457675 scopus 로고    scopus 로고
    • Cognitive dysfunction, hippocampal atrophy and glucocorticoid feedback in Alzheimer's disease
    • Elgh E., Lindqvist Astot A., Fagerlund M., Eriksson S., Olsson T., and Nasman B. Cognitive dysfunction, hippocampal atrophy and glucocorticoid feedback in Alzheimer's disease. Biol. Psychiatry 59 (2006) 155-161
    • (2006) Biol. Psychiatry , vol.59 , pp. 155-161
    • Elgh, E.1    Lindqvist Astot, A.2    Fagerlund, M.3    Eriksson, S.4    Olsson, T.5    Nasman, B.6
  • 16
    • 0026352497 scopus 로고
    • Inhibition of glucocorticoid secretion by the hippocampal formation in the primate
    • Sapolsky R.M., Zola-Morgan S., and Squire L.R. Inhibition of glucocorticoid secretion by the hippocampal formation in the primate. J. Neurosci. 11 (1991) 3695-3704
    • (1991) J. Neurosci. , vol.11 , pp. 3695-3704
    • Sapolsky, R.M.1    Zola-Morgan, S.2    Squire, L.R.3
  • 17
    • 17844371033 scopus 로고    scopus 로고
    • Mechanism of the anti-inflammatory effect of thiazolidinediones: relationship with the glucocorticoid pathway
    • Ialenti A., Grassia G., Di Meglio P., Maffia P., Di Rosa M., and Ianaro A. Mechanism of the anti-inflammatory effect of thiazolidinediones: relationship with the glucocorticoid pathway. Mol. Pharmacol. 67 (2005) 1620-1628
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1620-1628
    • Ialenti, A.1    Grassia, G.2    Di Meglio, P.3    Maffia, P.4    Di Rosa, M.5    Ianaro, A.6
  • 18
    • 58149461547 scopus 로고    scopus 로고
    • L. Matthews, A. Berry, M. Tersigni, F. D'Acquisto, A. Ianaro, D. Ray, Thiazolidinediones are partial agonists for the glucocorticoid receptor, Endocrinology, (2008). [Epub ahead of print, doi: 10.1210/en.2008-0196].
    • L. Matthews, A. Berry, M. Tersigni, F. D'Acquisto, A. Ianaro, D. Ray, Thiazolidinediones are partial agonists for the glucocorticoid receptor, Endocrinology, (2008). [Epub ahead of print, doi: 10.1210/en.2008-0196].
  • 20
    • 33646677275 scopus 로고    scopus 로고
    • Opposing effects of AMPA and 5-HT1A receptor blockade on passive avoidance and object recognition performance: correlation with AMPA receptor subunit expression in rat hippocampus
    • Schiapparelli L., Simón A., Del Río J., and Frechilla D. Opposing effects of AMPA and 5-HT1A receptor blockade on passive avoidance and object recognition performance: correlation with AMPA receptor subunit expression in rat hippocampus. Neuropharmacology 50 (2006) 897-907
    • (2006) Neuropharmacology , vol.50 , pp. 897-907
    • Schiapparelli, L.1    Simón, A.2    Del Río, J.3    Frechilla, D.4
  • 22
    • 0035666488 scopus 로고    scopus 로고
    • Do glucocorticoids contribute to brain aging?
    • Nichols N.R., Zieba M., and Bye N. Do glucocorticoids contribute to brain aging?. Brain Res. Rev. 37 (2001) 273-286
    • (2001) Brain Res. Rev. , vol.37 , pp. 273-286
    • Nichols, N.R.1    Zieba, M.2    Bye, N.3
  • 23
    • 33748253471 scopus 로고    scopus 로고
    • Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease
    • Green K.N., Billings L.M., Roozendaal B., McGaugh J.L., and LaFerla F.M. Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease. J. Neurosci. 26 (2006) 9047-9056
    • (2006) J. Neurosci. , vol.26 , pp. 9047-9056
    • Green, K.N.1    Billings, L.M.2    Roozendaal, B.3    McGaugh, J.L.4    LaFerla, F.M.5
  • 24
    • 33646227916 scopus 로고    scopus 로고
    • Chronic stress accelerates learning memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model
    • Jeong Y.H., Park C.H., Yoo J., Shin K.Y., Ahn S.M., Kim H.S., Lee S.H., Emson P.C., and Suh Y.H. Chronic stress accelerates learning memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model. FASEB J. 20 (2006) 729-731
    • (2006) FASEB J. , vol.20 , pp. 729-731
    • Jeong, Y.H.1    Park, C.H.2    Yoo, J.3    Shin, K.Y.4    Ahn, S.M.5    Kim, H.S.6    Lee, S.H.7    Emson, P.C.8    Suh, Y.H.9
  • 26
    • 36949038203 scopus 로고    scopus 로고
    • The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications
    • Jiang Q., Heneka M., and Landreth G.E. The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications. CNS Drugs 22 (2008) 1-14
    • (2008) CNS Drugs , vol.22 , pp. 1-14
    • Jiang, Q.1    Heneka, M.2    Landreth, G.E.3
  • 27
    • 0031437277 scopus 로고    scopus 로고
    • Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption
    • Oitzl M.S., de Kloet E.R., Joels M., Schmid W., and Cole T.J. Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption. Eur. J. Neurosci. 9 (1997) 2284-2296
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 2284-2296
    • Oitzl, M.S.1    de Kloet, E.R.2    Joels, M.3    Schmid, W.4    Cole, T.J.5
  • 28
    • 0023870756 scopus 로고
    • Antiglucocorticoid RU 38486 attenuates retention of a behaviour and disinhibits the hypothalamic-pituitary adrenal axis at different brain sites
    • De Kloet E.R., De Kock S., Schild V., and Veldhuis H.D. Antiglucocorticoid RU 38486 attenuates retention of a behaviour and disinhibits the hypothalamic-pituitary adrenal axis at different brain sites. Neuroendocrinology 47 (1988) 109-115
    • (1988) Neuroendocrinology , vol.47 , pp. 109-115
    • De Kloet, E.R.1    De Kock, S.2    Schild, V.3    Veldhuis, H.D.4
  • 29
    • 0036019156 scopus 로고    scopus 로고
    • Reduction of neuronal intranuclear rodlets immunoreactive for tubulin and glucocorticoid receptor in Alzheimer's disease
    • Woulfe J.M., Hammond R., Richardson B., Sooriabalan D., Parks W., Rippstein P., and Muñoz D.G. Reduction of neuronal intranuclear rodlets immunoreactive for tubulin and glucocorticoid receptor in Alzheimer's disease. Brain Pathol. 12 (2002) 300-307
    • (2002) Brain Pathol. , vol.12 , pp. 300-307
    • Woulfe, J.M.1    Hammond, R.2    Richardson, B.3    Sooriabalan, D.4    Parks, W.5    Rippstein, P.6    Muñoz, D.G.7
  • 30
    • 0036218016 scopus 로고    scopus 로고
    • Decrements in nuclear glucocorticoid receptor (GR) protein levels and DNA binding in aged rat hippocampus
    • Murphy E.K., Spencer R.L., Sipe K.J., and Herman J.P. Decrements in nuclear glucocorticoid receptor (GR) protein levels and DNA binding in aged rat hippocampus. Endocrinology 143 (2002) 1362-1370
    • (2002) Endocrinology , vol.143 , pp. 1362-1370
    • Murphy, E.K.1    Spencer, R.L.2    Sipe, K.J.3    Herman, J.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.