-
1
-
-
0035584857
-
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
-
Nordberg J Arnér ES (2001) Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 31, 1287 1312.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1287-1312
-
-
Nordberg, J.1
Arnér, E.S.2
-
2
-
-
0036219486
-
A review of the French maritime pine bark extract (Pycnogenol®), a herbal medication with a diverse clinical pharmacology
-
Rohdewald P (2002) A review of the French maritime pine bark extract (Pycnogenol®), a herbal medication with a diverse clinical pharmacology. Int J Clin Pharmacol Ther 40, 158 168.
-
(2002)
Int J Clin Pharmacol Ther
, vol.40
, pp. 158-168
-
-
Rohdewald, P.1
-
3
-
-
0032839592
-
Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol
-
Packer L, Rimbach G Virgili F (1999) Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol. Free Radic Biol Med 27, 704 724.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 704-724
-
-
Packer, L.1
Rimbach, G.2
Virgili, F.3
-
4
-
-
20444495261
-
Pycnogenol® protects DNA against oxidative damage in vivo
-
Rohdewald P (2005) Pycnogenol® protects DNA against oxidative damage in vivo. Phytother Res 19, 262.
-
(2005)
Phytother Res
, vol.19
, pp. 262
-
-
Rohdewald, P.1
-
5
-
-
0035005680
-
Treatment of vascular retinopathies with Pycnogenol®
-
Spadea L Balestrazzi E (2001) Treatment of vascular retinopathies with Pycnogenol®. Phytother Res 15, 219 223.
-
(2001)
Phytother Res
, vol.15
, pp. 219-223
-
-
Spadea, L.1
Balestrazzi, E.2
-
6
-
-
0345059061
-
Pycnogenol®, French maritime pine bark extract, improves endothelial function of hypertensive patients
-
Liu X, Wei J, Tan F, Zhou S, Wurthwein G Rohdewald P (2004) Pycnogenol®, French maritime pine bark extract, improves endothelial function of hypertensive patients. Life Sci 74, 855 862.
-
(2004)
Life Sci
, vol.74
, pp. 855-862
-
-
Liu, X.1
Wei, J.2
Tan, F.3
Zhou, S.4
Wurthwein, G.5
Rohdewald, P.6
-
7
-
-
1442324389
-
French maritime pine bark extract Pycnogenol® dose-dependently lowers glucose in type 2 diabetic patients
-
Liu X, Zhou HJ Rohdewald P (2004) French maritime pine bark extract Pycnogenol® dose-dependently lowers glucose in type 2 diabetic patients. Diabetes Care 27, 839.
-
(2004)
Diabetes Care
, vol.27
, pp. 839
-
-
Liu, X.1
Zhou, H.J.2
Rohdewald, P.3
-
8
-
-
34250318625
-
From selenium to selenoproteins: Synthesis, identity, and their role in human health
-
Papp LV, Lu J, Holmgren A Khanna KK (2007) From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid Redox Signal 9, 775 806.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 775-806
-
-
Papp, L.V.1
Lu, J.2
Holmgren, A.3
Khanna, K.K.4
-
9
-
-
0029031370
-
Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols
-
Björnstedt M, Hamberg M, Kumar S, Xue J Holmgren A (1995) Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. J Biol Chem 270, 11761 11764.
-
(1995)
J Biol Chem
, vol.270
, pp. 11761-11764
-
-
Björnstedt, M.1
Hamberg, M.2
Kumar, S.3
Xue, J.4
Holmgren, A.5
-
10
-
-
0034845193
-
Evolution of selenocysteine-containing proteins: Significance of identification and functional characterization of selenoproteins
-
Gladyshev VN Kryukov GV (2001) Evolution of selenocysteine-containing proteins: significance of identification and functional characterization of selenoproteins. Biofactors 14, 87 92.
-
(2001)
Biofactors
, vol.14
, pp. 87-92
-
-
Gladyshev, V.N.1
Kryukov, G.V.2
-
11
-
-
0033775891
-
Physiological functions of thioredoxin and thioredoxin reductase
-
Arnér ES Holmgren A (2000) Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem 267, 6102 6109.
-
(2000)
Eur J Biochem
, vol.267
, pp. 6102-6109
-
-
Arnér, E.S.1
Holmgren, A.2
-
12
-
-
0031229845
-
Selenium and the thioredoxin and glutaredoxin systems
-
Björnstedt M, Kumar S, Björkhem L, Spyrou G Holmgren A (1997) Selenium and the thioredoxin and glutaredoxin systems. Biomed Environ Sci 10, 271 279.
-
(1997)
Biomed Environ Sci
, vol.10
, pp. 271-279
-
-
Björnstedt, M.1
Kumar, S.2
Björkhem, L.3
Spyrou, G.4
Holmgren, A.5
-
13
-
-
0037462640
-
The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. a novel mechanism for defense against oxidative stress
-
Xia L, Nordman T, Olsson JM, Damdimopoulos A, Björkhem-Bergman L, Nalvarte I, Eriksson LC, Arnér ES, Spyrou G Björnstedt M (2003) The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress. J Biol Chem 278, 2141 2146.
-
(2003)
J Biol Chem
, vol.278
, pp. 2141-2146
-
-
Xia, L.1
Nordman, T.2
Olsson, J.M.3
Damdimopoulos, A.4
Björkhem-Bergman, L.5
Nalvarte, I.6
Eriksson, L.C.7
Arnér, E.S.8
Spyrou, G.9
Björnstedt, M.10
-
14
-
-
0029973142
-
Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene
-
Gladyshev VN, Jeang KT Stadtman TC (1996) Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene. Proc Natl Acad Sci USA 93, 6146 6151.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6146-6151
-
-
Gladyshev, V.N.1
Jeang, K.T.2
Stadtman, T.C.3
-
15
-
-
0030020576
-
A new selenoprotein from human lung adenocarcinoma cells: Purification, properties, and thioredoxin reductase activity
-
Tamura T Stadtman TC (1996) A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity. Proc Natl Acad Sci USA 93, 1006 1011.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1006-1011
-
-
Tamura, T.1
Stadtman, T.C.2
-
16
-
-
0032502720
-
Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue
-
Zhong L, Arnér ES, Ljung J, Aslund F Holmgren A (1998) Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue. J Biol Chem 273, 8581 8591.
-
(1998)
J Biol Chem
, vol.273
, pp. 8581-8591
-
-
Zhong, L.1
Arnér, E.S.2
Ljung, J.3
Aslund, F.4
Holmgren, A.5
-
17
-
-
0034674566
-
Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations
-
Zhong L Holmgren A (2000) Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations. J Biol Chem 275, 18121 18128.
-
(2000)
J Biol Chem
, vol.275
, pp. 18121-18128
-
-
Zhong, L.1
Holmgren, A.2
-
18
-
-
0017653811
-
Bovine thioredoxin system. Purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction
-
Holmgren A (1977) Bovine thioredoxin system. Purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction. J Biol Chem 252, 4600 4606.
-
(1977)
J Biol Chem
, vol.252
, pp. 4600-4606
-
-
Holmgren, A.1
-
20
-
-
4644318801
-
An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling
-
Damdimopoulos AE, Miranda-Vizuete A, Treuter E, Gustafsson JA Spyrou G (2004) An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling. J Biol Chem 279, 38721 38729.
-
(2004)
J Biol Chem
, vol.279
, pp. 38721-38729
-
-
Damdimopoulos, A.E.1
Miranda-Vizuete, A.2
Treuter, E.3
Gustafsson, J.A.4
Spyrou, G.5
-
21
-
-
0035793630
-
Heterogeneity within animal thioredoxin reductases. Evidence for alternative first exon splicing
-
Sun QA, Zappacosta F, Factor VM, Wirth PJ, Hatfield DL Gladyshev VN (2001) Heterogeneity within animal thioredoxin reductases. Evidence for alternative first exon splicing. J Biol Chem 276, 3106 3114.
-
(2001)
J Biol Chem
, vol.276
, pp. 3106-3114
-
-
Sun, Q.A.1
Zappacosta, F.2
Factor, V.M.3
Wirth, P.J.4
Hatfield, D.L.5
Gladyshev, V.N.6
-
22
-
-
0033621335
-
Novel selenoproteins identified in silico and in vivo by using a conserved RNA structural motif
-
Lescure A, Gautheret D, Carbon P Krol A (1999) Novel selenoproteins identified in silico and in vivo by using a conserved RNA structural motif. J Biol Chem 274, 38147 38154.
-
(1999)
J Biol Chem
, vol.274
, pp. 38147-38154
-
-
Lescure, A.1
Gautheret, D.2
Carbon, P.3
Krol, A.4
-
23
-
-
0242277285
-
The thioredoxin system - From science to clinic
-
Gromer S, Urig S Becker K (2004) The thioredoxin system - from science to clinic. Med Res Rev 24, 40 89.
-
(2004)
Med Res Rev
, vol.24
, pp. 40-89
-
-
Gromer, S.1
Urig, S.2
Becker, K.3
-
24
-
-
34548067718
-
Thioredoxin signaling as a target for cancer therapy
-
Powis G Kirkpatrick DL (2007) Thioredoxin signaling as a target for cancer therapy. Curr Opin Pharmacol 7, 392 397.
-
(2007)
Curr Opin Pharmacol
, vol.7
, pp. 392-397
-
-
Powis, G.1
Kirkpatrick, D.L.2
-
25
-
-
33751181030
-
On the potential of thioredoxin reductase inhibitors for cancer therapy
-
Urig S Becker K (2006) On the potential of thioredoxin reductase inhibitors for cancer therapy. Semin Cancer Biol 16, 452 465.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 452-465
-
-
Urig, S.1
Becker, K.2
-
26
-
-
33746430147
-
Thioredoxin reductase as a novel molecular target for cancer therapy
-
Nguyen P, Awwad RT, Smart DD, Spitz DR Gius D (2006) Thioredoxin reductase as a novel molecular target for cancer therapy. Cancer Lett 236, 164 174.
-
(2006)
Cancer Lett
, vol.236
, pp. 164-174
-
-
Nguyen, P.1
Awwad, R.T.2
Smart, D.D.3
Spitz, D.R.4
Gius, D.5
-
27
-
-
0029740378
-
Selenite and selenate inhibit human lymphocyte growth via different mechanisms
-
Spyrou G, Björnstedt M, Skog S Holmgren A (1996) Selenite and selenate inhibit human lymphocyte growth via different mechanisms. Cancer Res 56, 4407 4412.
-
(1996)
Cancer Res
, vol.56
, pp. 4407-4412
-
-
Spyrou, G.1
Björnstedt, M.2
Skog, S.3
Holmgren, A.4
-
28
-
-
0030570764
-
Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase
-
Arnér ES, Nordberg J Holmgren A (1996) Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase. Biochem Biophys Res Commun 225, 268 274.
-
(1996)
Biochem Biophys Res Commun
, vol.225
, pp. 268-274
-
-
Arnér, E.S.1
Nordberg, J.2
Holmgren, A.3
-
29
-
-
0026694318
-
Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen
-
Kumar S, Björnstedt M Holmgren A (1992) Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen. Eur J Biochem 207, 435 439.
-
(1992)
Eur J Biochem
, vol.207
, pp. 435-439
-
-
Kumar, S.1
Björnstedt, M.2
Holmgren, A.3
-
30
-
-
0026739327
-
Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase
-
Björnstedt M, Kumar S Holmgren A (1992) Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase. J Biol Chem 267, 8030 8034.
-
(1992)
J Biol Chem
, vol.267
, pp. 8030-8034
-
-
Björnstedt, M.1
Kumar, S.2
Holmgren, A.3
-
31
-
-
31544439083
-
Selenium bioavailability from buckwheat bran in rats fed a modified AIN-93G torula yeast-based diet
-
Reeves PG, Leary PD, Gregoire BR, Finley JW, Lindlauf JE Johnson LK (2005) Selenium bioavailability from buckwheat bran in rats fed a modified AIN-93G torula yeast-based diet. J Nutr 135, 2627 2633.
-
(2005)
J Nutr
, vol.135
, pp. 2627-2633
-
-
Reeves, P.G.1
Leary, P.D.2
Gregoire, B.R.3
Finley, J.W.4
Lindlauf, J.E.5
Johnson, L.K.6
-
32
-
-
27644506592
-
Insights into the hierarchy of selenium incorporation
-
Berry MJ (2005) Insights into the hierarchy of selenium incorporation. Nat Genet 37, 1162 1163.
-
(2005)
Nat Genet
, vol.37
, pp. 1162-1163
-
-
Berry, M.J.1
-
33
-
-
33750683907
-
Metabolism of 76Se-methylselenocysteine compared with that of 77Se-selenomethionine and 82Se-selenite
-
Suzuki KT, Doi C Suzuki N (2006) Metabolism of 76Se-methylselenocysteine compared with that of 77Se-selenomethionine and 82Se-selenite. Toxicol Appl Pharmacol 217, 185 195.
-
(2006)
Toxicol Appl Pharmacol
, vol.217
, pp. 185-195
-
-
Suzuki, K.T.1
Doi, C.2
Suzuki, N.3
-
34
-
-
0042920821
-
Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by sulforaphane and other electrophiles via an antioxidant response element
-
Hintze KJ, Wald KA, Zeng H, Jeffery EH Finley JW (2003) Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by sulforaphane and other electrophiles via an antioxidant response element. J Nutr 133, 2721 2727.
-
(2003)
J Nutr
, vol.133
, pp. 2721-2727
-
-
Hintze, K.J.1
Wald, K.A.2
Zeng, H.3
Jeffery, E.H.4
Finley, J.W.5
-
35
-
-
0033775650
-
Thioredoxin reductase as a pathophysiological factor and drug target
-
Becker K, Gromer S, Schirmer RH Muller S (2000) Thioredoxin reductase as a pathophysiological factor and drug target. Eur J Biochem 267, 6118 6125.
-
(2000)
Eur J Biochem
, vol.267
, pp. 6118-6125
-
-
Becker, K.1
Gromer, S.2
Schirmer, R.H.3
Muller, S.4
-
36
-
-
0037094345
-
Drug-resistant human lung cancer cells are more sensitive to selenium cytotoxicity. Effects on thioredoxin reductase and glutathione reductase
-
Björkhem-Bergman L, Jonsson K, Eriksson LC, Olsson JM, Lehmann S, Paul C Björnstedt M (2002) Drug-resistant human lung cancer cells are more sensitive to selenium cytotoxicity. Effects on thioredoxin reductase and glutathione reductase. Biochem Pharmacol 63, 1875 1884.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 1875-1884
-
-
Björkhem-Bergman, L.1
Jonsson, K.2
Eriksson, L.C.3
Olsson, J.M.4
Lehmann, S.5
Paul, C.6
Björnstedt, M.7
-
37
-
-
29744466425
-
Determination of serum proteins by means of the biuret reaction
-
Gornall AG, Bardawill CJ David MM (1949) Determination of serum proteins by means of the biuret reaction. J Biol Chem 177, 751 766.
-
(1949)
J Biol Chem
, vol.177
, pp. 751-766
-
-
Gornall, A.G.1
Bardawill, C.J.2
David, M.M.3
-
38
-
-
0029187491
-
Thioredoxin and thioredoxin reductase
-
Holmgren A Björnstedt M (1995) Thioredoxin and thioredoxin reductase. Methods Enzymol 252, 199 208.
-
(1995)
Methods Enzymol
, vol.252
, pp. 199-208
-
-
Holmgren, A.1
Björnstedt, M.2
-
39
-
-
0017067418
-
Glutathione peroxidase activity in selenium-deficient rat liver
-
Lawrence RA Burk RF (1976) Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 71, 952 958.
-
(1976)
Biochem Biophys Res Commun
, vol.71
, pp. 952-958
-
-
Lawrence, R.A.1
Burk, R.F.2
-
40
-
-
33846952526
-
Quantification of alternative mRNA species and identification of thioredoxin reductase 1 isoforms in human tumor cells
-
Rundlöf AK, Fernandes AP, Selenius M, Babic M, Shariatgorji M, Nilsonne G, Ilag LL, Dobra K Björnstedt M (2007) Quantification of alternative mRNA species and identification of thioredoxin reductase 1 isoforms in human tumor cells. Differentiation 75, 123 132.
-
(2007)
Differentiation
, vol.75
, pp. 123-132
-
-
Rundlöf, A.K.1
Fernandes, A.P.2
Selenius, M.3
Babic, M.4
Shariatgorji, M.5
Nilsonne, G.6
Ilag, L.L.7
Dobra, K.8
Björnstedt, M.9
|