Synthesis and anticonvulsant activity of certain substituted furochromone, benzofuran and flavone derivatives

Chemical and Pharmaceutical Bulletin

Volumn 58, Issue 9, 2010, Pages 1148-1156

  Ragab, Fatma Abdel Fattah ^a   El Sayed, Nehad Aboul Magd ^a   Eissa, Amal Abdel Haleem Mohamed ^a   El Kerdawy, Ahmed Mahmoud ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Anticonvulsant; Benzofuran; Chromone; Flavone; Neuroprotective activity

Indexed keywords

2 [(4,9 DIMETHOXY 5 OXO 5H FURO[3,2 G]CHROMEN 6 YL)METHYLENE] N ETHYLHYDRAZINECARBOTHIOAMIDE; 2 [(4,9 DIMETHOXY 5 OXO 5H FURO[3,2 G]CHROMEN 6 YL)METHYLENE] N METHYLHYDRAZINECARBOTHIOAMIDE; 2 [(4,9 DIMETHOXY 5 OXO 5H FURO[3,2 G]CHROMEN 6 YL)METHYLENE] N PHENYLHYDRAZINECARBOTHIOAMIDE; 2 [(4,9 DIMETHOXY 5 OXO 5H FURO[3,2 G]CHROMEN 6 YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE; 2 [(7 HYDROXY 5 METHOXY 4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE] N METHYLHYDRAZINECARBOTHIOAMIDE; 2 [(7 HYDROXY 5 METHOXY 4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE] N PHENYLHYDRAZINECARBOTHIOAMIDE; 2 [(7 HYDROXY 5 METHOXY 4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE; 2 [1 (6 HYDROXY 4 METHOXY 1 BENZOFURAN 5 YL)ETHYLIDENE] N METHYLHYDRAZINECARBOTHIOAMIDE; 2 [1 (6 HYDROXY 4 METHOXY 1 BENZOFURAN 5 YL)ETHYLIDENE]HYDRAZINECARBOTHIOAMIDE; 2 [1 (6 HYDROXY 4,7 DIMETHOXY 1 BENZOFURAN 5 YL)ETHYLIDENE] N METHYLHYDRAZINECARBOTHIOAMIDE; 2 [1 (6 HYDROXY 4,7 DIMETHOXY 1 BENZOFURAN 5 YL)ETHYLIDENE]HYDRAZINECARBOTHIOAMIDE; 2 [[(4,9 DIMETHOXY 5 OXO 5H FURO[3,2 G]CHROMEN 6 YL)METHYLENE]HYDRAZONO] 3 METHYL 1,3 THIAZOLIDIN 4 ONE; 2 [[(4,9 DIMETHOXY 5 OXO 5H FURO[3,2 G]CHROMEN-6-YL)METHYLENE]HYDRAZONO] 3 ETHYL 1,3 THIAZOLIDIN 4 ONE; 2 [[(7 HYDROXY 5 METHOXY 4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE]HYDRAZONO] 1,3 THIAZOLIDIN 4 ONE; 2 [[(7 HYDROXY 5 METHOXY 4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE]HYDRAZONO] 3 METHYL 1,3 THIAZOLIDIN 4 ONE; 3 ALLYL 2 [[(4,9 DIMETHOXY 5 OXO 5H FURO[3,2 G]CHROMEN 6 YL)METHYLENE]HYDRAZONO] 1,3 THIAZOLIDIN 4 ONE; ANTICONVULSIVE AGENT; BENZOFURAN DERIVATIVE; FLAVONE DERIVATIVE; FUROCHROMONE DERIVATIVE; N ALLYL 2 [(4,9 DIMETHOXY 5 OXO 5H FURO[3,2 G]CHROMEN 6 YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE; N ALLYL 2 [(7 HYDROXY 5 METHOXY 4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE; N ALLYL 2 [1 (6 HYDROXY 4 METHOXY 1 BENZOFURAN 5 YL)ETHYLIDENE]HYDRAZINECARBOTHIOAMIDE; N ALLYL 2 [1 (6 HYDROXY 4,7 DIMETHOXY 1 BENZOFURAN 5 YL)ETHYLIDENE]HYDRAZINECARBOTHIOAMIDE; N ETHYL 2 [(7 HYDROXY 5 METHOXY 4 OXO 2 PHENYL 4H CHROMEN 6 YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE; N ETHYL 2 [1 (6 HYDROXY 4 METHOXY 1 BENZOFURAN 5 YL)ETHYLIDENE]HYDRAZINECARBOTHIOAMIDE; N ETHYL 2 [1 (6 HYDROXY 4,7 DIMETHOXY 1 BENZOFURAN 5 YL)ETHYLIDENE]HYDRAZINECARBOTHIOAMIDE; PHENYTOIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CLONIC SEIZURE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC SHOCK; FEMALE; LETHALITY; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; STRUCTURE ACTIVITY RELATION; TONIC SEIZURE;

ANIMALS; ANTICONVULSANTS; BENZOFURANS; CHROMONES; ELECTROSHOCK; FEMALE; FLAVONES; MALE; MICE; MOLECULAR STRUCTURE; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77956320912     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.58.1148     Document Type: Article

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